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Term:CAF-1 complex
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Accession:GO:0033186 term browser browse the term
Definition:A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.
Comment:In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90.
Synonyms:exact_synonym: chromatin assembly factor 1 complex

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CAF-1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chaf1a chromatin assembly factor 1 subunit A part_of IBA
RGD PMID:8858152, PMID:21873635 RGD:13792537 NCBI chr 9:11,000,869...11,027,631
Ensembl chr 9:11,001,129...11,027,506
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G Chaf1b chromatin assembly factor 1 subunit B part_of ISO
RGD PMID:8858152, PMID:21873635 RGD:13792537 NCBI chr11:34,101,248...34,121,371
Ensembl chr11:34,101,197...34,121,378
JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor part_of ISO (PMID:8858152) RGD PMID:8858152 NCBI chr 5:147,499,880...147,535,240
Ensembl chr 5:147,499,882...147,535,240
JBrowse link

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  cellular_component 20142
    protein-containing complex 6031
      CAF-1 complex 3
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