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ONTOLOGY REPORT - ANNOTATIONS


Term:V(D)J recombination
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Accession:GO:0033151 term browser browse the term
Definition:The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
Synonyms:exact_synonym: V(D)J joining;   V-J joining;   V-J recombination
 xref: Wikipedia:V(D)J_recombination


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V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Dcaf1 DDB1 and CUL4 associated factor 1 JBrowse link 8 115,538,365 115,615,282 RGD:1624291
G Dclre1c DNA cross-link repair 1C JBrowse link 17 78,782,512 78,812,140 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Lig1 DNA ligase 1 JBrowse link 1 75,356,212 75,394,757 RGD:1624291
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:1624291
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
RGD:13792537
G Rag2 recombination activating 2 JBrowse link 3 91,191,837 91,200,134 RGD:1624291
RGD:13792537
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:1624291
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Polb DNA polymerase beta JBrowse link 16 74,237,001 74,260,272 RGD:1624291
immunoglobulin V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
RGD:13792537
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
RGD:13792537
G Tcf3 transcription factor 3 JBrowse link 7 12,146,642 12,168,400 RGD:1624291
RGD:13792537
RGD:1600115
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
RGD:13792537
T cell receptor V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:1600115
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Tcf7 transcription factor 7 JBrowse link 10 37,616,033 37,646,027 RGD:1624291
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    immune system process 2692
      somatic diversification of immune receptors 81
        somatic diversification of immune receptors via germline recombination within a single locus 74
          V(D)J recombination 19
            T cell receptor V(D)J recombination 6
            immunoglobulin V(D)J recombination + 6
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      cellular metabolic process 10737
        cellular aromatic compound metabolic process 5503
          nucleobase-containing compound metabolic process 5276
            nucleic acid metabolic process 4782
              DNA metabolic process 887
                DNA recombination 309
                  somatic cell DNA recombination 74
                    somatic diversification of immune receptors via germline recombination within a single locus 74
                      V(D)J recombination 19
                        T cell receptor V(D)J recombination 6
                        immunoglobulin V(D)J recombination + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.