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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of intracellular steroid hormone receptor signaling pathway
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Accession:GO:0033143 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
Synonyms:exact_synonym: regulation of steroid hormone receptor signalling pathway
 broad_synonym: regulation of steroid hormone receptor signaling pathway


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regulation of intracellular steroid hormone receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10459853) Ensembl
MGI		 PMID:10459853 GO_REF:0000107 NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200 		JBrowse link
negative regulation of androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G ESR2 estrogen receptor 2 acts_upstream_of_or_within ISO (PMID:12370428) MGI PMID:12370428 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303 		JBrowse link
G FOXH1 forkhead box H1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:141,240,691...141,244,381
Ensembl chr 8:144,225,933...144,232,736 		JBrowse link
G FOXP1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173 		JBrowse link
G HDAC1 histone deacetylase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,578,373...31,619,970
Ensembl chr 1:32,585,791...32,626,410 		JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:38,913,549...38,929,798
Ensembl chr 1:40,240,118...40,256,933 		JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:18827067) MGI PMID:18827067 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in ISO (PMID:20812024) UniProt PMID:20812024 NCBI chr17:34,934,452...35,121,195 JBrowse link
G NCOR2 nuclear receptor corepressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:121,913,368...122,155,031
Ensembl chr12:126,201,779...126,372,745 		JBrowse link
G NODAL nodal growth differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972 		JBrowse link
G PHB1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790 		JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:40,067,901...40,196,078
Ensembl chr18:43,622,455...43,728,675 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in ISO (PMID:19277043) UniProt PMID:19277043 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952 		JBrowse link
G TCF21 transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:131,656,582...131,662,983
Ensembl chr 6:135,754,896...135,761,294 		JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in ISO (PMID:20812024) UniProt PMID:20812024 NCBI chr19:3,066,554...3,090,285 JBrowse link
negative regulation of glucocorticoid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISO (MGI:5567887|PMID:24378737) UniProt PMID:24378737 MGI:5567887 NCBI chr11:13,436,580...13,547,135
Ensembl chr11:13,163,028...13,240,376 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,391,310...68,509,813
Ensembl chr 4:75,018,898...75,066,726 		JBrowse link
G CRY1 cryptochrome circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:104,558,874...104,658,833
Ensembl chr12:107,954,262...108,052,484 		JBrowse link
G CRY2 cryptochrome circadian regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,801,504...45,837,357
Ensembl chr11:46,293,717...46,329,759 		JBrowse link
G PER1 period circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,502,080...43,518,098
Ensembl chr17:48,234,360...48,250,391 		JBrowse link
G PHB1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790 		JBrowse link
negative regulation of intracellular estrogen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G CNOT1 CCR4-NOT transcription complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:38,793,212...38,902,686
Ensembl chr16:57,919,283...58,027,472 		JBrowse link
G CNOT2 CCR4-NOT transcription complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:67,753,703...67,865,375
Ensembl chr12:70,520,722...70,633,149 		JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:105,826,633...105,854,415
Ensembl chr2B:224,422,467...224,450,133 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12370428) Ensembl
MGI		 PMID:12370428 GO_REF:0000107 NCBI chr 8:61,135,307...61,335,838
Ensembl chr 8:62,806,637...63,006,386 		JBrowse link
G FOXH1 forkhead box H1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:141,240,691...141,244,381
Ensembl chr 8:144,225,933...144,232,736 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in ISO PMID:11043578 BHF-UCL PMID:11043578 RGD:8554127 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674 		JBrowse link
G KANK2 KN motif and ankyrin repeat domains 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:10,713,582...10,746,371
Ensembl chr19:11,426,149...11,457,359 		JBrowse link
G LBH LBH regulator of WNT signaling pathway involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:30,244,474...30,273,048
Ensembl chr2A:30,320,249...30,411,779 		JBrowse link
G PHB2 prohibitin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17065319)
(PMID:17785450)		 Ensembl
MGI		 PMID:17065319 PMID:17785450 GO_REF:0000107 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053 		JBrowse link
G STRN3 striatin 3 ISO RGD PMID:18434427 RGD:2311258 NCBI chr14:11,668,426...11,798,776
Ensembl chr14:29,869,414...29,997,838 		JBrowse link
G TP63 tumor protein p63 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104 		JBrowse link
G VPS11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:31015428) FlyBase PMID:31015428 NCBI chr11:113,905,989...113,920,163
Ensembl chr11:117,835,557...117,849,389 		JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,836,707...19,846,231
Ensembl chr15:38,086,518...38,095,835 		JBrowse link
G ZNF366 zinc finger protein 366 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:42,805,429...42,873,109
Ensembl chr 5:43,404,640...43,471,868 		JBrowse link
negative regulation of intracellular steroid hormone receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALR calreticulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,501,013...12,506,909
Ensembl chr19:13,242,900...13,249,416 		JBrowse link
G HMGA2 high mobility group AT-hook 2 ISO RGD PMID:11390395 RGD:1601592 NCBI chr12:22,954,946...23,096,623 JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:22,903,403...22,908,527
Ensembl chr  X:30,459,527...30,464,652 		JBrowse link
G RHOA ras homolog family member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16254014) Ensembl
MGI		 PMID:16254014 GO_REF:0000107 NCBI chr 3:49,282,009...49,339,887 JBrowse link
positive regulation of glucocorticoid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor acts_upstream_of_or_within ISO PMID:23878391 MGI PMID:23878391 RGD:10047172 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239 		JBrowse link
G LMO3 LIM domain only 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,544,474...16,605,925
Ensembl chr12:16,902,025...16,997,809 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 ISO RGD PMID:17481888 RGD:5688226 NCBI chr 8:66,632,139...66,929,526
Ensembl chr 8:68,293,018...68,400,479 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:22001115 RGD:5686284 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 acts_upstream_of_or_within ISO PMID:23878391 MGI PMID:23878391 RGD:10047172 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit ISO RGD PMID:8943293 RGD:8694070 NCBI chr19:43,329,680...43,373,282
Ensembl chr19:51,865,317...51,909,027 		JBrowse link
positive regulation of intracellular estrogen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14676301) Ensembl
MGI		 PMID:14676301 GO_REF:0000107 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357 		JBrowse link
G FOXA1 forkhead box A1 involved_in ISO (PMID:16087863) UniProt PMID:16087863 NCBI chr14:18,347,284...18,352,705 JBrowse link
G FSHR follicle stimulating hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11089565) Ensembl
MGI		 PMID:11089565 GO_REF:0000107 NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258 		JBrowse link
G KMT2D lysine methyltransferase 2D involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,689,463...39,731,904
Ensembl chr12:40,575,083...40,608,661 		JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20351249) Ensembl
MGI		 PMID:20351249 GO_REF:0000107 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 ISO RGD PMID:11713241 RGD:727330 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549 		JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr16:30,186,326...30,190,654 JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23493398 RGD:10413906 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356 		JBrowse link
G SKP2 S-phase kinase associated protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17785450) Ensembl
MGI		 PMID:17785450 GO_REF:0000107 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311 		JBrowse link
G SRARP steroid receptor associated and regulated protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:15,141,681...15,144,147
Ensembl chr 1:16,134,435...16,136,875 		JBrowse link
G WBP2 WW domain binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:69,796,205...69,806,290
Ensembl chr17:75,346,204...75,356,463 		JBrowse link
positive regulation of intracellular steroid hormone receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NCOA3 nuclear receptor coactivator 3 ISO glucocorticoid receptor signaling in astrocytes RGD PMID:16179382 RGD:1642052 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549 		JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I ISO glucocorticoid receptor, independent of sumoylation activity or presence of a GME RGD PMID:11812797 RGD:2301354 Ensembl chr16:1,367,288...1,382,575 JBrowse link
regulation of androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,594,956...58,603,570
Ensembl chr17:63,689,082...63,696,142 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G KDM5D lysine demethylase 5D involved_in ISO (PMID:27185910) UniProt PMID:27185910
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 acts_upstream_of_or_within ISO PMID:9920921 MGI PMID:9920921 RGD:70792 NCBI chr18:40,067,901...40,196,078
Ensembl chr18:43,622,455...43,728,675 		JBrowse link
G PRMT2 protein arginine methyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:33,100,101...33,130,060
Ensembl chr21:46,233,951...46,263,570 		JBrowse link
G RNF14 ring finger protein 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:137,316,493...137,351,061
Ensembl chr 5:143,441,497...143,461,355 		JBrowse link
G RNF6 ring finger protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:7,505,669...7,515,542
Ensembl chr13:25,854,765...25,864,629 		JBrowse link
G SAFB2 scaffold attachment factor B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26092125) Ensembl
MGI
TreeGrafter		 PMID:26092125 GO_REF:0000107 GO_REF:0000118 NCBI chr19:4,604,150...4,639,991
Ensembl chr19:5,539,679...5,575,560 		JBrowse link
G TRIM68 tripartite motif containing 68 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:4,773,343...4,782,898
Ensembl chr11:4,438,329...4,447,899 		JBrowse link
G USP26 ubiquitin specific peptidase 26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,155,933...122,160,000
Ensembl chr  X:132,463,140...132,465,887 		JBrowse link
regulation of intracellular estrogen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARM1 coactivator associated arginine methyltransferase 1 involved_in ISO (MGI:4887320|PMID:19843527) UniProt PMID:19843527 MGI:4887320 NCBI chr19:10,424,993...10,476,702
Ensembl chr19:11,144,733...11,195,948 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:34,382,064...34,469,432
Ensembl chr15:52,711,349...52,791,281 		JBrowse link
G FSHR follicle stimulating hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18063689), (PMID:18676690) Ensembl
MGI		 PMID:18063689 PMID:18676690 GO_REF:0000107 NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258 		JBrowse link
G LOC100991443 katanin p60 ATPase-containing subunit A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:147,413,892...147,467,587
Ensembl chr 6:152,119,206...152,173,113
Ensembl chr 6:152,119,206...152,173,113 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16007215) Ensembl
MGI		 PMID:16007215 GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G UBA5 ubiquitin like modifier activating enzyme 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:129,732,314...129,752,579
Ensembl chr 3:137,209,715...137,227,147 		JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:94,356,440...94,389,920
Ensembl chr 6:98,242,756...98,274,377 		JBrowse link
G UFM1 ubiquitin fold modifier 1 involved_in ISO (PMID:25219498) UniProt PMID:25219498 NCBI chr13:19,571,114...19,584,259
Ensembl chr13:38,162,598...38,175,814 		JBrowse link
G UFSP2 UFM1 specific peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:177,562,642...177,589,312
Ensembl chr 4:189,779,242...189,805,572 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      signal transduction 5440
        regulation of signal transduction 3007
          regulation of intracellular steroid hormone receptor signaling pathway 79
            negative regulation of intracellular steroid hormone receptor signaling pathway + 40
            positive regulation of intracellular steroid hormone receptor signaling pathway + 19
            regulation of androgen receptor signaling pathway + 27
            regulation of ecdysone receptor-mediated signaling pathway + 0
            regulation of glucocorticoid receptor signaling pathway + 12
            regulation of intracellular estrogen receptor signaling pathway + 36
Path 2
Term Annotations click to browse term
  biological_process 16440
    response to stimulus 8500
      cellular response to stimulus 7062
        cellular response to chemical stimulus 2979
          cellular response to organic substance 2228
            cellular response to hormone stimulus 761
              hormone-mediated signaling pathway 185
                steroid hormone mediated signaling pathway 131
                  intracellular steroid hormone receptor signaling pathway 119
                    regulation of intracellular steroid hormone receptor signaling pathway 79
                      negative regulation of intracellular steroid hormone receptor signaling pathway + 40
                      positive regulation of intracellular steroid hormone receptor signaling pathway + 19
                      regulation of androgen receptor signaling pathway + 27
                      regulation of ecdysone receptor-mediated signaling pathway + 0
                      regulation of glucocorticoid receptor signaling pathway + 12
                      regulation of intracellular estrogen receptor signaling pathway + 36
paths to the root