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ONTOLOGY REPORT - ANNOTATIONS


Term:extrathymic T cell differentiation
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Accession:GO:0033078 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: extrathymic T cell development



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extrathymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btnl3 butyrophilin-like 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,474,056...4,489,024
Ensembl chr20:4,474,056...4,489,024
JBrowse link
G Il15 interleukin 15 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2136897 (PMID:10704459)
Ensembl
RGD
PMID:10704459 GO_REF:0000107 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
regulation of extrathymic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prdm1 PR/SET domain 1 involved_in ISO (MGI:5779429|PMID:27102484) RGD PMID:27102484 MGI:5779429 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Zfp683 zinc finger protein 683 involved_in ISO (MGI:5779429|PMID:27102484) RGD PMID:27102484 MGI:5779429 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      leukocyte activation 1052
        lymphocyte activation 851
          lymphocyte differentiation 448
            T cell differentiation 324
              extrathymic T cell differentiation 4
                extrathymic T cell selection + 2
                negative regulation of extrathymic T cell differentiation 0
                positive regulation of extrathymic T cell differentiation 0
                regulation of extrathymic T cell differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      cellular developmental process 4768
        cell differentiation 4767
          cell development 3311
            hemopoiesis 1064
              leukocyte differentiation 676
                mononuclear cell differentiation 545
                  lymphocyte differentiation 448
                    T cell differentiation 324
                      extrathymic T cell differentiation 4
                        extrathymic T cell selection + 2
                        negative regulation of extrathymic T cell differentiation 0
                        positive regulation of extrathymic T cell differentiation 0
                        regulation of extrathymic T cell differentiation + 2
paths to the root