Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:DNA recombinase mediator complex
go back to main search page
Accession:GO:0033061 term browser browse the term
Definition:A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange.
Comment:Many paralogs of Rad51 act as recombinase mediators. These paralogs dimerize (or occasionally form tetramers) amongst themselves to form complexes with ssDNA-binding activity, and which act as mediators of Rad51 presynaptic filament assembly.


show annotations for term's descendants           Sort by:
 
Rad51B-Rad51C-Rad51D-XRCC2 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad51b RAD51 paralog B ISO
IBA
(PMID:11751635)
PMID:21873635
RGD PMID:11751635, PMID:21873635 RGD:13792537 NCBI chr 6:102,473,978...103,018,185
Ensembl chr 6:102,477,036...102,512,505
JBrowse link
G Rad51c RAD51 paralog C ISO
IBA
(PMID:11751635)
PMID:21873635
RGD PMID:11751635, PMID:21873635 RGD:13792537 NCBI chr10:74,697,713...74,724,004
Ensembl chr10:74,697,716...74,724,472
JBrowse link
G Rad51d RAD51 paralog D ISO
IBA
(PMID:11751635)
PMID:21873635
RGD PMID:11751635, PMID:21873635 RGD:13792537 NCBI chr10:70,222,703...70,241,352
Ensembl chr10:70,227,163...70,241,254
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 ISO
IBA
(PMID:11751635)
PMID:21873635
RGD PMID:11751635, PMID:21873635 RGD:13792537 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
Rad51C-XRCC3 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad51c RAD51 paralog C ISO
IBA
(PMID:11751635)
PMID:21873635
RGD PMID:11751635, PMID:21873635 RGD:13792537 NCBI chr10:74,697,713...74,724,004
Ensembl chr10:74,697,716...74,724,472
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO
IBA
(PMID:11751635)
PMID:21873635
RGD PMID:11751635, PMID:21873635 RGD:13792537 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
Swi5-Sfr1 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07067300.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 9:38,799,881...38,800,143 JBrowse link
G AC134087.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:150,994,665...150,994,913 JBrowse link
G RGD1561465 similar to RIKEN cDNA 2900010J23 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:150,994,650...150,995,029 JBrowse link
G Sfr1 SWI5-dependent homologous recombination repair protein 1 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(MGI:MGI:4868525|PMID:20976249)
(PMID:21252223)
Ensembl
UniProt
RGD
PMID:20976249, PMID:21252223, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4868525, RGD:13792537 NCBI chr 1:267,505,336...267,509,350
Ensembl chr 1:267,483,145...267,509,350
JBrowse link
G Swi5 SWI5 homologous recombination repair protein ISO
IBA
ISS
(PMID:21252223)
PMID:21873635
GO_REF:0000024
(MGI:MGI:4868525|PMID:20976249)
RGD
UniProt
PMID:20976249, PMID:21252223, PMID:21873635 GO_REF:0000024, MGI:MGI:4868525, RGD:13792537 NCBI chr 3:11,307,981...11,317,049
Ensembl chr 3:11,307,981...11,317,049
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      DNA recombinase mediator complex 10
        Rad51B-Rad51C complex 0
        Rad51B-Rad51C-Rad51D-XRCC2 complex 4
        Rad51C-XRCC3 complex 2
        Rhp55-Rhp57 complex 0
        Swi5-Sfr1 complex 5
        XRCC2-RAD51D complex 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.