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ONTOLOGY REPORT - ANNOTATIONS

Term:mast cell homeostasis
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Accession:GO:0033023 term browser browse the term
Definition:The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Comment:Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus.


show annotations for term's descendants           Sort by:
mast cell homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig acts_upstream_of ISO (PMID:14764707) MGI PMID:14764707 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G IL3 interleukin 3 acts_upstream_of ISO (PMID:12714518) MGI PMID:12714518 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G KITLG KIT ligand involved_in
acts_upstream_of		 IEA
ISO		 (PMID:12714518) Ensembl
MGI		 PMID:12714518 GO_REF:0000107 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15039234) Ensembl
MGI		 PMID:15039234 GO_REF:0000107 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of ISO (PMID:15947484) MGI PMID:15947484 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
negative regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (PMID:12714518) MGI PMID:12714518 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G KITLG KIT ligand involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12714518) Ensembl
MGI		 PMID:12714518 GO_REF:0000107 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:15947484) MGI PMID:15947484 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
positive regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15039234) Ensembl
MGI		 PMID:15039234 GO_REF:0000107 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISS (PMID:10433800) BHF-UCL PMID:10433800 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    immune system process 3226
      leukocyte homeostasis 140
        mast cell homeostasis 7
          mast cell apoptotic process + 6
Path 2
Term Annotations click to browse term
  biological_process 19669
    homeostatic process 2069
      multicellular organismal-level homeostasis 998
        homeostasis of number of cells 424
          leukocyte homeostasis 140
            mast cell homeostasis 7
              mast cell apoptotic process + 6
paths to the root