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ONTOLOGY REPORT - ANNOTATIONS


Term:mast cell homeostasis
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Accession:GO:0033023 term browser browse the term
Definition:The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Comment:Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus.



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mast cell homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:6112943|PMID:29155995)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:29155995 GO_REF:0000024 GO_REF:0000107 MGI:6112943 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480
JBrowse link
negative regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (MGI:2670544|PMID:12714518) RGD PMID:12714518 MGI:2670544 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (MGI:2670544|PMID:12714518) RGD PMID:12714518 MGI:2670544 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (MGI:3605581|PMID:15947484) RGD PMID:15947484 MGI:3605581 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:3828408|PMID:14625290) RGD PMID:14625290 MGI:3828408 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    immune system process 2829
      myeloid cell homeostasis 199
        mast cell homeostasis 6
          mast cell apoptotic process + 5
Path 2
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological quality 4205
        homeostatic process 2024
          homeostasis of number of cells 364
            leukocyte homeostasis 118
              mast cell homeostasis 6
                mast cell apoptotic process + 5
paths to the root