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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mast cell activation
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Accession:GO:0033003 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell activation.

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regulation of mast cell activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISS
ISO		 GO_REF:0000024
(MGI:3703139|PMID:16272347)		 UniProt
RGD		 PMID:16272347 GO_REF:0000024 MGI:3703139 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Plscr1 phospholipid scramblase 1 IMP PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217 		JBrowse link
G Ptpre protein tyrosine phosphatase, receptor type, E ISO (MGI:4412219|PMID:19508371) RGD PMID:19508371 MGI:4412219 NCBI chr 1:207,820,719...207,987,123
Ensembl chr 1:207,887,209...207,987,136 		JBrowse link
negative regulation of mast cell activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300lf Cd300 molecule-like family member F ISO
ISS		 (PMID:24035150)
(MGI:5451118|PMID:23123064)
GO_REF:0000024		 RGD
UniProt		 PMID:23123064 PMID:24035150 GO_REF:0000024 MGI:5451118 NCBI chr10:103,669,781...103,690,584
Ensembl chr10:103,670,028...103,687,425 		JBrowse link
G Cd84 CD84 molecule ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865 		JBrowse link
G Cnr1 cannabinoid receptor 1 IDA RGD PMID:18552882 RGD:2316220 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 IDA RGD PMID:18552882 RGD:2316220 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 ISS
ISO
IEA		 GO_REF:0000024
(MGI:4461821|PMID:20526344)
GO_REF:0000002		 UniProt
RGD
InterPro		 PMID:20526344 GO_REF:0000002 GO_REF:0000024 MGI:4461821 NCBI chr10:94,944,243...94,961,795
Ensembl chr10:94,944,436...94,961,791 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO MGI:3051384 (MGI:3050742|PMID:15235600) RGD PMID:15235600 MGI:3050742 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959 		JBrowse link
negative regulation of mast cell activation involved in immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (PMID:16339535) RGD PMID:16339535 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 ISS
ISO		 GO_REF:0000024
(MGI:5660449|PMID:25692702)		 UniProt
RGD		 PMID:25692702 GO_REF:0000024 MGI:5660449 NCBI chr 1:21,613,148...21,684,483
Ensembl chr 1:21,613,148...21,684,480 		JBrowse link
G Fer FER tyrosine kinase IEA
ISO
ISS		 GO_REF:0000107
(MGI:3694314|PMID:16731527)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16731527 GO_REF:0000024 GO_REF:0000107 MGI:3694314 NCBI chr 9:111,557,804...111,868,583
Ensembl chr 9:111,597,037...111,862,670 		JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (PMID:16339535)
(MGI:3721168|PMID:12874256)		 RGD PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947 		JBrowse link
G Cd84 CD84 molecule ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865 		JBrowse link
G Foxf1 forkhead box F1 ISO MGI:2179135 (MGI:4367570|PMID:18421012) RGD PMID:18421012 MGI:4367570 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 IEA
ISO		 GO_REF:0000107
MGI:2653910 (MGI:3589858|PMID:15944273)		 Ensembl
RGD		 PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061 		JBrowse link
G Lgals9 galectin 9 ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO MGI:3051384 (MGI:3050742|PMID:15235600) RGD PMID:15235600 MGI:3050742 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Pla2g3 phospholipase A2, group III ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)		 RGD PMID:23624557 MGI:5492190 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614 		JBrowse link
G Snx4 sorting nexin 4 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:70,693,381...70,753,620
Ensembl chr11:70,693,366...70,753,632 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IEA
ISO		 GO_REF:0000107
(PMID:18253931)		 Ensembl
RGD		 PMID:18253931 GO_REF:0000107 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755 		JBrowse link
positive regulation of mast cell activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032888.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr18:87,415,531...87,415,884 JBrowse link
G Cd226 CD226 molecule ISO
IBA		 (PMID:16831868)
PMID:21873635		 RGD PMID:16831868, PMID:21873635 RGD:13792537 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765 		JBrowse link
G Cd300lb CD300 molecule-like family member b ISO (MGI:4821898|PMID:20566714) RGD PMID:20566714 MGI:4821898 NCBI chr10:103,471,082...103,481,071
Ensembl chr10:103,467,725...103,481,153 		JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:11781380 RGD:11567226 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 ISO (PMID:17242164) RGD PMID:17242164 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543 		JBrowse link
G Dppa1 developmental pluripotency associated 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:31,693,219...31,712,924
Ensembl chr10:31,693,219...31,712,924 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO
IBA		 (MGI:4821898|PMID:20566714)
PMID:21873635		 RGD PMID:20566714, PMID:21873635 MGI:4821898, RGD:13792537 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379 		JBrowse link
G LOC100359777 mCG12681-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:31,603,613...31,620,449
Ensembl chr10:31,603,613...31,620,443 		JBrowse link
G LOC689968 similar to kidney injury molecule 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:31,647,519...31,661,204
Ensembl chr10:31,647,898...31,661,344 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO
IBA		 (PMID:16831868)
PMID:21873635		 RGD PMID:16831868, PMID:21873635 RGD:13792537 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585 		JBrowse link
G Timd2 T-cell immunoglobulin and mucin domain containing 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:31,755,473...31,796,423
Ensembl chr10:31,755,510...31,790,263 		JBrowse link
G Tslp thymic stromal lymphopoietin ISO (PMID:17242164) RGD PMID:17242164 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISS
ISO		 GO_REF:0000024
(MGI:5586645|PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 MGI:5586645 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637 		JBrowse link
positive regulation of mast cell activation involved in immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277 		JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IEA
ISO		 GO_REF:0000107
(MGI:3776334|PMID:11454903)		 Ensembl
RGD		 PMID:11454903 GO_REF:0000107 MGI:3776334 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365 		JBrowse link
G Adora3 adenosine A3 receptor ISO MGI:2155986 (MGI:2664591|PMID:12817016) RGD PMID:12817016 MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISS
ISO		 GO_REF:0000024
(MGI:5294498|PMID:21746961)		 UniProt
RGD		 PMID:21746961 GO_REF:0000024 MGI:5294498 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745 		JBrowse link
G Gab2 GRB2-associated binding protein 2 ISS
ISO		 GO_REF:0000024
(MGI:2137187|PMID:11449275)		 UniProt
RGD		 PMID:11449275 GO_REF:0000024 MGI:2137187 NCBI chr 1:162,082,876...162,283,379
Ensembl chr 1:162,083,030...162,279,727 		JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066 		JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Il13 interleukin 13 ISO MGI:1931804|MGI:96556 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il4 interleukin 4 ISO
IBA		 MGI:1857195|MGI:96541 (MGI:3589858|PMID:15944273)
PMID:21873635		 RGD PMID:15944273, PMID:21873635 MGI:3589858, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il4r interleukin 4 receptor ISO MGI:1861951 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386 		JBrowse link
G Nppc natriuretic peptide C IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636 		JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730 		JBrowse link
G Sphk2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277 		JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175 		JBrowse link
G Syk spleen associated tyrosine kinase IMP
IBA
ISO
IEA		 PMID:21873635
MGI:2384078 (MGI:85068|PMID:9000133)
GO_REF:0000107		 RGD
Ensembl		 PMID:9000133, PMID:16861349, PMID:21873635 GO_REF:0000107 MGI:85068, RGD:2299903, RGD:13792537 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653 		JBrowse link
G Fer FER tyrosine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:111,557,804...111,868,583
Ensembl chr 9:111,597,037...111,862,670 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase ISO
IBA		 (PMID:19001085)
PMID:21873635		 RGD PMID:19001085, PMID:21873635 RGD:13792537 NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:3703139|PMID:16272347)		 UniProt
RGD		 PMID:16272347, PMID:21873635 GO_REF:0000024 MGI:3703139, RGD:13792537 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO (MGI:5298334|PMID:21063107) RGD PMID:21063107 MGI:5298334 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448 		JBrowse link
G Rac2 Rac family small GTPase 2 ISO (MGI:3655336|PMID:10843388) RGD PMID:10843388 MGI:3655336 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098 		JBrowse link
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed IDA
IBA		 PMID:25122211
PMID:21873635		 UniProt
GO_Central		 PMID:25122211, PMID:21873635 RGD:10047193, RGD:13792537 NCBI chr 4:159,483,089...159,518,387
Ensembl chr 4:159,483,131...159,515,447 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:12482918 RGD:2312429 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175 		JBrowse link
G Unc13d unc-13 homolog D IEA
ISO		 GO_REF:0000107
(PMID:15548590)		 Ensembl
RGD		 PMID:15548590 GO_REF:0000107 NCBI chr10:104,613,907...104,628,664
Ensembl chr10:104,613,928...104,628,676 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    immune system process 2842
      leukocyte activation 1058
        regulation of leukocyte activation 698
          regulation of mast cell activation 59
            negative regulation of mast cell activation + 13
            positive regulation of mast cell activation + 37
            regulation of mast cell activation involved in immune response + 40
Path 2
Term Annotations click to browse term
  biological_process 20030
    biological regulation 13774
      regulation of biological process 13076
        regulation of cellular process 12564
          regulation of cell activation 744
            regulation of leukocyte activation 698
              regulation of mast cell activation 59
                negative regulation of mast cell activation + 13
                positive regulation of mast cell activation + 37
                regulation of mast cell activation involved in immune response + 40
paths to the root