regulation of actin filament-based process - Ontology Report

(MGI:5086051|PMID:21685893)

PMID:21685893

MGI:5086051

NCBI chr14:32,093,017...32,334,665
Ensembl chr14:50,540,193...50,620,955

PARD3

par-3 family cell polarity regulator

acts_upstream_of_or_within

(MGI:5086051|PMID:21685893)

PMID:21685893

MGI:5086051

NCBI chr10:34,225,791...34,933,907
Ensembl chr10:34,808,380...35,393,287

ROCK1

Rho associated coiled-coil containing protein kinase 1

involved_in
acts_upstream_of_or_within

(MGI:5086051|PMID:21685893)

Ensembl
MGI

PMID:21685893

GO_REF:0000107 MGI:5086051

NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086

actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AVIL

advillin

involved_in

GO_REF:0000043

NCBI chr12:31,108,569...31,129,307
Ensembl chr12:31,369,872...31,389,847

CAPZA1

capping actin protein of muscle Z-line subunit alpha 1

involved_in

GO_REF:0000043

NCBI chr 1:115,273,497...115,324,353
Ensembl chr 1:125,028,519...125,078,892

CAPZA2

capping actin protein of muscle Z-line subunit alpha 2

involved_in

GO_REF:0000043

NCBI chr 7:108,835,083...108,889,112
Ensembl chr 7:121,551,401...121,584,566

CAPZA3

capping actin protein of muscle Z-line subunit alpha 3

involved_in

GO_REF:0000043

NCBI chr12:18,733,149...18,734,224
Ensembl chr12:19,119,771...19,120,670

CAPZB

capping actin protein of muscle Z-line subunit beta

involved_in

GO_REF:0000043

NCBI chr 1:18,297,434...18,444,011
Ensembl chr 1:19,344,154...19,488,133

gelsolin

involved_in

Ensembl
UniProt

GO_REF:0000043 GO_REF:0000107

NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831

MYH9

myosin heavy chain 9

NOT|involved_in

(MGI:5619440|PMID:23325791)

PMID:23325791

MGI:5619440

NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618

SCIN

scinderin

involved_in

GO_REF:0000107

NCBI chr 7:13,269,361...13,351,854
Ensembl chr 7:12,613,996...12,696,244

SPTA1

spectrin alpha, erythrocytic 1

involved_in

GO_REF:0000043

NCBI chr 1:133,969,717...134,045,301
Ensembl chr 1:137,760,942...137,835,927

SPTAN1

spectrin alpha, non-erythrocytic 1

involved_in

GO_REF:0000043

NCBI chr 9:99,674,819...99,755,973
Ensembl chr 9:128,341,739...128,422,971

SPTB

spectrin beta, erythrocytic

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr14:45,329,658...45,466,597
Ensembl chr14:64,209,453...64,288,851

SPTBN1

spectrin beta, non-erythrocytic 1

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr2A:54,608,711...54,816,083
Ensembl chr2A:55,822,415...55,961,925

SPTBN2

spectrin beta, non-erythrocytic 2

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr11:62,042,617...62,086,634
Ensembl chr11:65,365,588...65,409,207

SPTBN4

spectrin beta, non-erythrocytic 4

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr19:37,515,420...37,621,473
Ensembl chr19:46,042,387...46,127,429

tropomyosin 1

NCBI chr15:41,989,239...42,018,520
Ensembl chr15:60,286,587...60,315,530

villin 1

involved_in

UniProt
Ensembl

GO_REF:0000043 GO_REF:0000107

NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550

VILL

villin like

involved_in

GO_REF:0000043

NCBI chr 3:37,883,869...37,906,054
Ensembl chr 3:38,172,789...38,189,188

actin filament uncapping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN2

actinin alpha 2

involved_in

GO_REF:0000107

NCBI chr 1:212,245,742...212,323,387
Ensembl chr 1:217,272,597...217,321,103

barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADD1

adducin 1

involved_in

(PMID:8626479)

PMID:8626479

NCBI chr 4:2,986,301...3,072,590
Ensembl chr 4:2,920,781...2,975,012

ADD2

adducin 2

involved_in

GO_REF:0000107

NCBI chr2A:70,724,454...70,831,248
Ensembl chr2A:71,839,470...71,895,106

CAPZA1

capping actin protein of muscle Z-line subunit alpha 1

acts_upstream_of_or_within
involved_in

(MGI:3758397|PMID:17656356)

MGI
UniProt
InterPro

PMID:17656356

GO_REF:0000002 GO_REF:0000104 MGI:3758397

NCBI chr 1:115,273,497...115,324,353
Ensembl chr 1:125,028,519...125,078,892

CAPZA2

capping actin protein of muscle Z-line subunit alpha 2

involved_in

InterPro
UniProt

GO_REF:0000002 GO_REF:0000104

NCBI chr 7:108,835,083...108,889,112
Ensembl chr 7:121,551,401...121,584,566

CAPZA3

capping actin protein of muscle Z-line subunit alpha 3

involved_in

UniProt
InterPro

GO_REF:0000002 GO_REF:0000104

NCBI chr12:18,733,149...18,734,224
Ensembl chr12:19,119,771...19,120,670

CAPZB

capping actin protein of muscle Z-line subunit beta

acts_upstream_of_or_within
involved_in

(MGI:3758397|PMID:17656356)

MGI
InterPro
UniProt

PMID:17656356

GO_REF:0000002 GO_REF:0000104 MGI:3758397

NCBI chr 1:18,297,434...18,444,011
Ensembl chr 1:19,344,154...19,488,133

DBNL

drebrin like

NOT|acts_upstream_of_or_within

(MGI:1353214|PMID:10637315)

PMID:10637315

MGI:1353214

NCBI chr 7:44,753,062...44,775,717
Ensembl chr 7:44,824,608...44,845,891

EPS8

epidermal growth factor receptor pathway substrate 8

involved_in

GO_REF:0000107

NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117

gelsolin

involved_in

GO_REF:0000104

NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831

radixin

NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557

twinfilin actin binding protein 1

involved_in

GO_REF:0000107

NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404

villin 1

involved_in

GO_REF:0000107

NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550

barbed-end actin filament uncapping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

capping protein regulator and myosin 1 linker 1

involved_in

GO_REF:0000107

NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092

negative regulation of actin cytoskeleton reorganization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TJP1

tight junction protein 1

involved_in

(PMID:25753039)

ARUK-UCL

PMID:25753039

NCBI chr15:981,198...1,249,292
Ensembl chr15:26,344,878...26,598,878

negative regulation of actin filament bundle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cofilin 1

NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806

drebrin 1

NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872

MAP3K1

mitogen-activated protein kinase kinase kinase 1

prevents phenylephrine-induced actin organization

PMID:9155015

RGD:2293527

NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959

profilin 1

involved_in

(PMID:23153535)

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

PRKN

parkin RBR E3 ubiquitin protein ligase

involved_in

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

SHANK1

SH3 and multiple ankyrin repeat domains 1

acts_upstream_of_or_within

(MGI:3846509|PMID:19208628)

PMID:19208628

MGI:3846509

NCBI chr19:47,623,474...47,684,476
Ensembl chr19:56,526,577...56,580,442

SHANK3

SH3 and multiple ankyrin repeat domains 3

acts_upstream_of_or_within

(MGI:3846509|PMID:19208628)

PMID:19208628

MGI:3846509

NCBI chr22:30,951,866...30,973,608

negative regulation of actin filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cofilin 1

NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806

LIMA1

LIM domain and actin binding 1

involved_in

GO_REF:0000107

NCBI chr12:38,473,223...38,580,511
Ensembl chr12:39,399,611...39,476,142

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977

PLEKHH2

pleckstrin homology, MyTH4 and FERM domain containing H2

involved_in

GO_REF:0000107

NCBI chr2A:43,723,791...43,852,380
Ensembl chr2A:44,570,356...44,700,272

SHROOM2

shroom family member 2

acts_upstream_of_or_within

(MGI:3723326|PMID:17666436)

PMID:17666436

MGI:3723326

NCBI chr X:2,418,883...2,580,853
Ensembl chr X:9,755,524...9,832,733

SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1 like

acts_upstream_of_or_within

(MGI:5433266|PMID:21703590)

PMID:21703590

MGI:5433266

NCBI chr22:5,078,435...5,224,090
Ensembl chr22:21,943,630...22,089,686

SWAP70

switching B cell complex subunit SWAP70

involved_in

GO_REF:0000107

NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422

negative regulation of actin filament polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adducin 1

NCBI chr 4:2,986,301...3,072,590
Ensembl chr 4:2,920,781...2,975,012

ARFGEF1

ADP ribosylation factor guanine nucleotide exchange factor 1

involved_in

GO_REF:0000107

NCBI chr 8:63,740,512...63,884,189
Ensembl chr 8:65,403,386...65,545,789

BBS4

Bardet-Biedl syndrome 4

acts_upstream_of_or_within
involved_in

(MGI:5510934|PMID:23716571)

GO_REF:0000107 MGI:5510934

NCBI chr15:51,601,526...51,656,460
Ensembl chr15:70,362,261...70,416,964

calpain 1

NCBI chr11:60,545,837...60,576,631
Ensembl chr11:63,886,015...63,916,021

CYRIB

CYFIP related Rac1 interactor B

involved_in

(PMID:30250061)

PMID:30250061

NCBI chr 8:126,478,020...126,653,936
Ensembl chr 8:129,209,655...129,272,844

FHOD3

formin homology 2 domain containing 3

acts_upstream_of_or_within
involved_in

(MGI:4422153|PMID:19706596)

PMID:19706596

GO_REF:0000107 MGI:4422153

NCBI chr18:29,550,049...30,033,130
Ensembl chr18:33,165,819...33,590,154

HIP1R

huntingtin interacting protein 1 related

involved_in

GO_REF:0000107

NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726

KANK1

KN motif and ankyrin repeat domains 1

involved_in
acts_upstream_of_or_within

PMID:17996375 PMID:18458160

(PMID:18458160)
(PMID:17996375)

UniProt
MGI

NCBI chr 9:550,713...556,230

KANK2

KN motif and ankyrin repeat domains 2

involved_in

GO_REF:0000002

NCBI chr19:10,713,582...10,746,371
Ensembl chr19:11,426,149...11,457,359

KANK4

KN motif and ankyrin repeat domains 4

involved_in

GO_REF:0000002

NCBI chr 1:61,489,350...61,578,025
Ensembl chr 1:63,307,644...63,350,546

LOC100986336

twinfilin-2

involved_in

Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743

MKKS

MKKS centrosomal shuttling protein

acts_upstream_of_or_within
involved_in

(MGI:5510934|PMID:23716571)

GO_REF:0000107 MGI:5510934

NCBI chr20:10,346,252...10,380,180
Ensembl chr20:10,351,309...10,366,863

MYADM

myeloid associated differentiation marker

involved_in

GO_REF:0000107

NCBI chr19:50,807,615...50,817,196
Ensembl chr19:59,663,790...59,664,758

PECAM1

platelet and endothelial cell adhesion molecule 1

NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067

profilin 1

involved_in

(PMID:7758455)

PMID:7758455

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

profilin 2

involved_in
acts_upstream_of_or_within

PMID:7758455 PMID:18001770

(PMID:7758455)
(MGI:4844066|PMID:18001770)

UniProt
MGI

MGI:4844066

NCBI chr 3:146,986,364...146,992,558

PRKCD

protein kinase C delta

involved_in

GO_REF:0000107

NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910

SLIT2

slit guidance ligand 2

involved_in

GO_REF:0000107

NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656

SSH1

slingshot protein phosphatase 1

involved_in

GO_REF:0000002

NCBI chr12:106,357,147...106,432,295
Ensembl chr12:109,758,399...109,823,444

SSH2

slingshot protein phosphatase 2

involved_in

GO_REF:0000002

NCBI chr17:26,845,369...27,148,615
Ensembl chr17:27,363,861...27,665,630

SSH3

slingshot protein phosphatase 3

involved_in

GO_REF:0000002

NCBI chr11:62,661,752...62,670,869
Ensembl chr11:65,975,486...65,983,716

TLR2

toll like receptor 2

involved_in

(MGI:5307186|PMID:22198949)

ARUK-UCL

PMID:22198949

MGI:5307186

NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331

twinfilin actin binding protein 1

involved_in

Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404

negative regulation of actin filament severing

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CSRP3

cysteine and glycine rich protein 3

acts_upstream_of_or_within

(PMID:24860983)

PMID:24860983

NCBI chr11:19,208,025...19,228,000
Ensembl chr11:19,121,234...19,140,820

MYH9

myosin heavy chain 9

involved_in

GO_REF:0000107

NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618

negative regulation of actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AP3S2

adaptor related protein complex 3 subunit sigma 2

involved_in

GO_REF:0000002

NCBI chr15:68,524,982...68,583,917

ARPIN

actin related protein 2/3 complex inhibitor

involved_in

GO_REF:0000002

NCBI chr15:68,585,634...68,602,105

coronin 1A

involved_in

GO_REF:0000107

Ensembl chr16:30,550,383...30,556,196

negative regulation of Arp2/3 complex-mediated actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CORO1B

coronin 1B

involved_in

GO_REF:0000107

NCBI chr11:62,796,461...62,802,204
Ensembl chr11:66,108,924...66,113,175

CTNNA2

catenin alpha 2

involved_in

GO_REF:0000107

NCBI chr2A:79,594,694...80,745,885
Ensembl chr2A:81,303,559...82,307,258

DNAI3

dynein axonemal intermediate chain 3

involved_in

GO_REF:0000107

NCBI chr 1:117,617,609...117,690,284
Ensembl chr 1:86,474,457...86,547,080

GMFG

glia maturation factor gamma

acts_upstream_of_or_within
involved_in

(MGI:5505367|PMID:23727094)

PMID:23727094

GO_REF:0000107 MGI:5505367

NCBI chr19:36,426,652...36,440,031
Ensembl chr19:44,974,435...44,982,209

HIP1R

huntingtin interacting protein 1 related

involved_in

GO_REF:0000107

NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726

LOC100972387

DNA-directed RNA polymerases I, II, and III subunit RPABC2

involved_in

PMID:18297063

NCBI chr22:18,868,872...18,988,918
Ensembl chr22:36,796,015...36,814,469

negative regulation of barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

capping protein regulator and myosin 1 linker 1

involved_in

GO_REF:0000107

NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092

CARMIL2

capping protein regulator and myosin 1 linker 2

involved_in

GO_REF:0000107

NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709

CRACD

capping protein inhibiting regulator of actin dynamics

involved_in

GO_REF:0000107

NCBI chr 4:67,598,880...67,880,269
Ensembl chr 4:74,167,488...74,199,802

negative regulation of cardiac myofibril assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SMAD4

SMAD family member 4

involved_in

GO_REF:0000107

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

negative regulation of hepatic stellate cell contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NOS1

nitric oxide synthase 1

NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005

negative regulation of muscle filament sliding

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

drebrin 1

NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872

negative regulation of sarcomere organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAV3

caveolin 3

involved_in

GO_REF:0000107

NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942

mitofusin 2

NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077

negative regulation of stress fiber assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

involved_in

GO_REF:0000107

NCBI chr11:67,763,944...67,831,728
Ensembl chr11:70,985,926...71,028,342

ARHGAP28

Rho GTPase activating protein 28

acts_upstream_of_or_within
involved_in

(MGI:5644775|PMID:25211221)

PMID:25211221

GO_REF:0000107 MGI:5644775

NCBI chr18:7,366,986...7,548,782
Ensembl chr18:9,690,107...9,775,270

ARHGAP6

Rho GTPase activating protein 6

involved_in

GO_REF:0000107

NCBI chr X:3,767,259...4,291,738
Ensembl chr X:11,058,207...11,582,115

CGNL1

cingulin like 1

involved_in

GO_REF:0000107

NCBI chr15:36,344,222...36,518,235
Ensembl chr15:54,669,190...54,831,595

CLASP1

cytoplasmic linker associated protein 1

involved_in

(PMID:24859005)

PMID:24859005

NCBI chr2B:8,265,626...8,574,282
Ensembl chr2B:121,840,484...122,102,793

CLASP2

cytoplasmic linker associated protein 2

involved_in

(PMID:24859005)

PMID:24859005

NCBI chr 3:33,418,300...33,640,185
Ensembl chr 3:33,721,153...33,938,560

CORO2B

coronin 2B

acts_upstream_of_or_within
involved_in

(MGI:6110508|PMID:29162887)

PMID:29162887

GO_REF:0000107 MGI:6110508

NCBI chr15:47,536,641...47,685,357
Ensembl chr15:66,370,374...66,452,545

DLC1

DLC1 Rho GTPase activating protein

involved_in

GO_REF:0000107

NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233

F11R

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890

FRMD7

FERM domain containing 7

acts_upstream_of_or_within
involved_in

(MGI:5546532|PMID:23967341)

PMID:23967341

GO_REF:0000107 MGI:5546532

NCBI chr X:121,208,961...121,259,708
Ensembl chr X:131,516,484...131,567,394

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

GO_REF:0000107

NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

MYOC

myocilin

involved_in

GO_REF:0000107

NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628

PAK2

p21 (RAC1) activated kinase 2

involved_in

GO_REF:0000107

NCBI chr 3:194,084,037...194,174,010
Ensembl chr 3:204,023,357...204,111,507

profilin 1

involved_in

(PMID:23153535)

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

PHLDB2

pleckstrin homology like domain family B member 2

involved_in

GO_REF:0000107

NCBI chr 3:108,878,798...109,120,501
Ensembl chr 3:115,745,634...116,044,586

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

involved_in

GO_REF:0000107

NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960

PPFIA1

PTPRF interacting protein alpha 1

acts_upstream_of_or_within
involved_in

(MGI:5492034|PMID:22266902)
(PMID:22266902)

PMID:22266902

GO_REF:0000107 MGI:5492034

NCBI chr11:65,368,262...65,486,023
Ensembl chr11:68,657,638...68,769,464

PPP1R9A

protein phosphatase 1 regulatory subunit 9A

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

RHPN1

rhophilin Rho GTPase binding protein 1

acts_upstream_of_or_within

(MGI:6316493|PMID:25071083)

PMID:25071083

MGI:6316493

NCBI chr 8:140,115,455...140,131,070
Ensembl chr 8:143,135,016...143,150,235

RHPN2

rhophilin Rho GTPase binding protein 2

acts_upstream_of_or_within
involved_in

(PMID:25071083)

PMID:25071083

GO_REF:0000107

NCBI chr19:29,901,608...29,988,476
Ensembl chr19:38,646,620...38,713,626

S1PR1

sphingosine-1-phosphate receptor 1

NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987

STMN1

stathmin 1

involved_in

(PMID:25198505)

PMID:25198505

NCBI chr 1:25,159,241...25,165,535
Ensembl chr 1:26,208,731...26,230,925

TACSTD2

tumor associated calcium signal transducer 2

involved_in

(MGI:5315060|PMID:22194864)

PMID:22194864

MGI:5315060

NCBI chr 1:57,838,661...57,841,444
Ensembl chr 1:59,545,625...59,546,596

TJP1

tight junction protein 1

involved_in

GO_REF:0000107

NCBI chr15:981,198...1,249,292
Ensembl chr15:26,344,878...26,598,878

TMEFF2

transmembrane protein with EGF like and two follistatin like domains 2

acts_upstream_of_or_within
involved_in

(PMID:24632071)

PMID:24632071

GO_REF:0000107

NCBI chr2B:79,242,825...79,489,113
Ensembl chr2B:197,158,689...197,396,254

WAS

WASP actin nucleation promoting factor

involved_in

GO_REF:0000107

NCBI chr X:40,982,132...40,989,767
Ensembl chr X:48,842,765...48,850,380

WASF2

WASP family member 2

involved_in

GO_REF:0000107

NCBI chr 1:26,665,853...26,750,618
Ensembl chr 1:27,717,538...27,737,316

negative regulation of ventricular cardiac muscle cell action potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BIN1

bridging integrator 1

involved_in

GO_REF:0000107

NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378

pointed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LMOD1

leiomodin 1

involved_in

GO_REF:0000002

NCBI chr 1:177,493,627...177,543,853
Ensembl chr 1:181,798,304...181,845,295

LMOD2

leiomodin 2

involved_in

GO_REF:0000002

NCBI chr 7:115,649,102...115,657,174
Ensembl chr 7:128,331,803...128,340,263

LMOD3

leiomodin 3

involved_in

GO_REF:0000002

NCBI chr 3:69,042,870...69,058,704
Ensembl chr 3:70,410,288...70,424,702

TMOD1

tropomodulin 1

involved_in

GO_REF:0000002

NCBI chr 9:68,592,195...68,692,001
Ensembl chr 9:96,714,237...96,813,936

TMOD2

tropomodulin 2

involved_in

GO_REF:0000002

NCBI chr15:30,690,641...30,757,960
Ensembl chr15:49,035,929...49,079,570

TMOD3

tropomodulin 3

involved_in

GO_REF:0000002

NCBI chr15:30,771,245...30,853,473
Ensembl chr15:49,100,716...49,182,218

TMOD4

tropomodulin 4

involved_in

GO_REF:0000002

NCBI chr 1:126,519,159...126,525,502
Ensembl chr 1:130,167,570...130,173,663

positive regulation of actin cytoskeleton reorganization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

(PMID:24863063)

PMID:24863063

NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

involved_in

GO_REF:0000107

NCBI chr 7:6,158,306...6,230,903
Ensembl chr 7:103,758,479...103,828,874

BCAS3

BCAS3 microtubule associated cell migration factor

involved_in

(MGI:5582152|PMID:22300583)

PMID:22300583

MGI:5582152

NCBI chr17:54,776,768...55,494,917
Ensembl chr17:59,901,453...60,613,732

cell division cycle 42

involved_in

(PMID:26051942)

PMID:26051942

NCBI chr 1:21,245,970...21,286,210

CSF3

colony stimulating factor 3

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729

FES

FES proto-oncogene, tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr15:69,576,936...69,588,834
Ensembl chr15:88,774,965...88,786,965

HAX1

HCLS1 associated protein X-1

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr 1:129,627,564...129,630,920
Ensembl chr 1:133,241,077...133,244,431

HCK

HCK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr20:28,346,244...28,395,370
Ensembl chr20:29,474,737...29,523,399

HRAS

HRas proto-oncogene, GTPase

involved_in

(PMID:23027131)

PMID:23027131

NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078

NRP1

neuropilin 1

involved_in

(PMID:24863063), (PMID:26051942)

PMID:24863063 PMID:26051942

NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648

NTF3

neurotrophin 3

involved_in

(PMID:23027130)

PMID:23027130

NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989

NTRK3

neurotrophic receptor tyrosine kinase 3

involved_in

(PMID:23027130)

PMID:23027130

NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204

TEK

TEK receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572

positive regulation of actin filament bundle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CX3CL1

C-X3-C motif chemokine ligand 1

involved_in

GO_REF:0000107

NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760

filamin A

NCBI chr X:143,799,088...143,825,282

ID1

inhibitor of DNA binding 1, HLH protein

NCBI chr20:27,895,177...27,896,414
Ensembl chr20:28,535,582...28,536,311

LIMK1

LIM domain kinase 1

involved_in

GO_REF:0000107

Ensembl chr 7:81,231,876...81,271,282

LOC100970287

synaptopodin

involved_in

(MGI:3577135|PMID:15841212)

PMID:15841212

MGI:3577135

NCBI chr 5:146,048,956...146,083,490
Ensembl chr 5:152,046,207...152,085,595

MTSS1

MTSS I-BAR domain containing 1

acts_upstream_of_or_within

(MGI:5317250|PMID:21406566)

PMID:21406566

MGI:5317250

NCBI chr 8:121,235,545...121,413,037
Ensembl chr 8:123,987,577...124,032,339

profilin 2

involved_in

(PMID:23153535)

NCBI chr 3:146,986,364...146,992,558

PLEK

pleckstrin

involved_in

GO_REF:0000107

NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393

SWAP70

switching B cell complex subunit SWAP70

involved_in

GO_REF:0000107

NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422

SYNPO2

synaptopodin 2

involved_in

(PMID:24005909)

PMID:24005909

NCBI chr 4:111,045,007...111,280,880
Ensembl chr 4:121,635,110...121,806,647

villin 1

involved_in

GO_REF:0000107

NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550

positive regulation of actin filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CFL1

cofilin 1

involved_in
acts_upstream_of_or_within

PMID:15548599 PMID:23921380

(MGI:5554982|PMID:23921380)
(MGI:3575233|PMID:15548599)

CACAO
MGI

MGI:3575233 MGI:5554982

NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806

CFL2

cofilin 2

involved_in

GO_REF:0000107

NCBI chr14:15,468,532...15,473,094
Ensembl chr14:33,655,744...33,659,473

DSTN

destrin, actin depolymerizing factor

acts_upstream_of_or_within

(MGI:3575233|PMID:15548599)

PMID:15548599

MGI:3575233

NCBI chr20:17,528,574...17,566,925
Ensembl chr20:17,506,262...17,545,331

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265

PLEK

pleckstrin

involved_in

GO_REF:0000107

NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393

SEMA5A

semaphorin 5A

involved_in

(MGI:5526935|PMID:19850054)

PMID:19850054

MGI:5526935

NCBI chr 5:9,349,473...9,852,183
Ensembl chr 5:9,168,549...9,564,356

villin 1

involved_in

GO_REF:0000107

NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550

WDR1

WD repeat domain 1

acts_upstream_of_or_within
involved_in

(MGI:5574550|PMID:24840128)

PMID:24840128

GO_REF:0000107 MGI:5574550

NCBI chr 4:4,487,054...4,516,732
Ensembl chr 4:9,805,164...9,848,032

positive regulation of actin filament polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTR3

actin related protein 3

NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729

ALOX15

arachidonate 15-lipoxygenase

involved_in

(MGI:5508294|PMID:11278875)

PMID:11278875

MGI:5508294

NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669

ARF6

ADP ribosylation factor 6

involved_in

GO_REF:0000107

NCBI chr14:30,482,191...30,486,741
Ensembl chr14:48,789,329...48,789,856

ARPC2

actin related protein 2/3 complex subunit 2

acts_upstream_of_or_within
involved_in

(MGI:3818245|PMID:18836449)

PMID:18836449

GO_REF:0000107 MGI:3818245

NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643

BAG4

BAG cochaperone 4

involved_in

(MGI:5292318|PMID:21712384)

PMID:21712384

MGI:5292318

NCBI chr 8:37,479,231...37,515,303
Ensembl chr 8:34,656,000...34,692,666

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

involved_in

GO_REF:0000107

NCBI chr 7:6,158,306...6,230,903
Ensembl chr 7:103,758,479...103,828,874

BIN1

bridging integrator 1

involved_in

GO_REF:0000107

NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378

capping protein regulator and myosin 1 linker 1

involved_in

GO_REF:0000107

NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092

CCL11

C-C motif chemokine ligand 11

involved_in

GO_REF:0000107

NCBI chr17:22,495,737...22,515,144
Ensembl chr17:22,806,076...22,808,345
Ensembl chr17:22,806,076...22,808,345

CCL21

C-C motif chemokine ligand 21

involved_in

GO_REF:0000107

NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924

CCL24

C-C motif chemokine ligand 24

involved_in

GO_REF:0000107

NCBI chr 7:68,206,688...68,210,343
Ensembl chr 7:82,263,310...82,265,480

CCL26

C-C motif chemokine ligand 26

involved_in

GO_REF:0000107

NCBI chr 7:68,230,804...68,251,369
Ensembl chr 7:82,221,846...82,242,874

CDC42EP2

CDC42 effector protein 2

involved_in

GO_REF:0000107

NCBI chr11:60,679,582...60,686,763
Ensembl chr11:64,024,281...64,024,913

CDC42EP5

CDC42 effector protein 5

involved_in

(PMID:11035016)

PMID:11035016

NCBI chr19:51,411,848...51,419,686

CRACD

capping protein inhibiting regulator of actin dynamics

involved_in

GO_REF:0000107

NCBI chr 4:67,598,880...67,880,269
Ensembl chr 4:74,167,488...74,199,802

CSF3

colony stimulating factor 3

involved_in

GO_REF:0000107

NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729

CTTN

cortactin

involved_in

GO_REF:0000107

NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857

DLG1

discs large MAGUK scaffold protein 1

acts_upstream_of_or_within
involved_in

(MGI:3528803|PMID:15699074)

PMID:15699074

GO_REF:0000107 MGI:3528803

NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987

EVL

Enah/Vasp-like

involved_in

(MGI:5545940|PMID:23153535)

MGI:5545940

NCBI chr14:80,594,889...80,767,652
Ensembl chr14:100,005,645...100,084,598

FCHSD1

FCH and double SH3 domains 1

involved_in

(MGI:6233193|PMID:23437151)

PMID:23437151

MGI:6233193

NCBI chr 5:137,000,158...137,012,379

FCHSD2

FCH and double SH3 domains 2

involved_in

(MGI:6233193|PMID:23437151)

PMID:23437151

MGI:6233193

NCBI chr11:67,915,796...68,219,482

FER

FER tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 5:104,099,620...104,548,077
Ensembl chr 5:109,964,823...110,350,576

FMN1

formin 1

acts_upstream_of_or_within
involved_in

(MGI:3027450|PMID:14647292)

PMID:14647292

GO_REF:0000107 MGI:3027450

NCBI chr15:11,271,794...11,698,539
Ensembl chr15:30,114,113...30,495,909

GRB2

growth factor receptor bound protein 2

acts_upstream_of_or_within
involved_in

(MGI:3768467|PMID:17923684)

GO_REF:0000107 MGI:3768467

NCBI chr17:69,265,307...69,352,835
Ensembl chr17:74,817,471...74,903,796

ICAM1

intercellular adhesion molecule 1

NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605

KIRREL1

kirre like nephrin family adhesion molecule 1

acts_upstream_of_or_within

(MGI:3768467|PMID:17923684)

MGI:3768467

NCBI chr 1:133,363,880...133,465,717
Ensembl chr 1:137,233,701...137,255,927

LMOD1

leiomodin 1

involved_in

GO_REF:0000107

NCBI chr 1:177,493,627...177,543,853
Ensembl chr 1:181,798,304...181,845,295

LMOD2

leiomodin 2

involved_in

GO_REF:0000107

NCBI chr 7:115,649,102...115,657,174
Ensembl chr 7:128,331,803...128,340,263

MAP3K1

mitogen-activated protein kinase kinase kinase 1

acts_upstream_of_or_within

(MGI:2674169|PMID:12941696), (MGI:5608927|PMID:25224220)

PMID:12941696 PMID:25224220

MGI:2674169 MGI:5608927

NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959

MLST8

MTOR associated protein, LST8 homolog

acts_upstream_of_or_within
involved_in

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr16:1,063,534...1,067,706
Ensembl chr16:2,306,451...2,310,828

MTOR

mechanistic target of rapamycin kinase

acts_upstream_of_or_within
involved_in

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

myosin IC

NCBI chr17:1,446,506...1,475,634
Ensembl chr17:1,345,143...1,375,540

NCK1

NCK adaptor protein 1

involved_in
acts_upstream_of_or_within

(MGI:3768467|PMID:17923684)

UniProt
MGI
Ensembl

GO_REF:0000104 GO_REF:0000107 MGI:3768467

NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444

NCK2

NCK adaptor protein 2

involved_in

Ensembl
UniProt

GO_REF:0000104 GO_REF:0000107

NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363

NCKAP1

NCK associated protein 1

involved_in

(MGI:5897521|PMID:27927633)

PMID:27927633

MGI:5897521

NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710

NCKAP1L

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

NPHS1

NPHS1 adhesion molecule, nephrin

involved_in
acts_upstream_of_or_within

(MGI:3768467|PMID:17923684)

Ensembl
MGI

GO_REF:0000107 MGI:3768467

NCBI chr19:32,742,802...32,770,600
Ensembl chr19:41,492,444...41,518,471

profilin 1

involved_in

(PMID:23153535)

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

profilin 2

involved_in
acts_upstream_of_or_within

PMID:17541406 PMID:23153535

(PMID:23153535)
(MGI:3714870|PMID:17541406)

UniProt
MGI

MGI:3714870

NCBI chr 3:146,986,364...146,992,558

PRKCE

protein kinase C epsilon

involved_in

GO_REF:0000107

NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313

PTK2B

protein tyrosine kinase 2 beta

involved_in

GO_REF:0000107

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

PYCARD

PYD and CARD domain containing

involved_in

GO_REF:0000107

NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828

RAC1

Rac family small GTPase 1

acts_upstream_of_or_within

(MGI:2668778|PMID:12853475)

PMID:12853475

MGI:2668778

NCBI chr 7:7,039,379...7,068,866

ras homolog family member A

NCBI chr 3:49,282,009...49,339,887

RICTOR

RPTOR independent companion of MTOR complex 2

acts_upstream_of_or_within
involved_in

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr 5:71,299,215...71,435,290
Ensembl chr 5:76,389,130...76,469,830

SNX9

sorting nexin 9

involved_in

GO_REF:0000107

NCBI chr 6:155,724,026...155,844,553
Ensembl chr 6:157,824,918...157,903,357

TENM1

teneurin transmembrane protein 1

involved_in

(MGI:5465054|PMID:22698694)

PMID:22698694

MGI:5465054

NCBI chr X:113,568,341...114,399,131
Ensembl chr X:123,742,330...124,333,000

VASP

vasodilator stimulated phosphoprotein

involved_in

GO_REF:0000107

NCBI chr19:42,457,222...42,476,688
Ensembl chr19:51,053,567...51,072,553

positive regulation of actin filament severing

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CSRP3

cysteine and glycine rich protein 3

acts_upstream_of_or_within

(PMID:24860983)

PMID:24860983

NCBI chr11:19,208,025...19,228,000
Ensembl chr11:19,121,234...19,140,820

positive regulation of actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FMN1

formin 1

acts_upstream_of_or_within
involved_in

(MGI:3027450|PMID:14647292)

PMID:14647292

GO_REF:0000107 MGI:3027450

NCBI chr15:11,271,794...11,698,539
Ensembl chr15:30,114,113...30,495,909

gelsolin

involved_in

GO_REF:0000107

NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831

MAGEL2

MAGE family member L2

acts_upstream_of_or_within
involved_in

(MGI:5603599|PMID:23452853)

PMID:23452853

GO_REF:0000107 MGI:5603599

NCBI chr15:6,017,523...6,021,849
Ensembl chr15:21,134,857...21,138,576

SCIN

scinderin

involved_in

GO_REF:0000107

NCBI chr 7:13,269,361...13,351,854
Ensembl chr 7:12,613,996...12,696,244

TRIM27

tripartite motif containing 27

acts_upstream_of_or_within

(MGI:5603599|PMID:23452853)

PMID:23452853

MGI:5603599

NCBI chr 6:28,722,505...28,743,484
Ensembl chr 6:29,390,423...29,411,308

WHAMM

WASP homolog associated with actin, golgi membranes and microtubules

involved_in

(PMID:18614018)

PMID:18614018

NCBI chr15:62,763,534...62,788,639
Ensembl chr15:80,706,760...80,730,006

positive regulation of Arp2/3 complex-mediated actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABI2

abl interactor 2

involved_in

(PMID:21107423)

PMID:21107423

NCBI chr2B:90,561,708...90,663,072
Ensembl chr2B:208,702,092...208,797,499

BRK1

BRICK1 subunit of SCAR/WAVE actin nucleating complex

involved_in

GO_REF:0000107

NCBI chr 3:10,051,054...10,062,364
Ensembl chr 3:10,403,896...10,415,545

CYFIP1

cytoplasmic FMR1 interacting protein 1

involved_in

GO_REF:0000107

Ensembl chr15:20,462,811...20,573,684

FCHSD2

FCH and double SH3 domains 2

involved_in

(PMID:29887380)

PMID:29887380

NCBI chr11:67,915,796...68,219,482

NCKAP1

NCK associated protein 1

involved_in

GO_REF:0000107

NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710

WASF1

WASP family member 1

involved_in

GO_REF:0000107

NCBI chr 6:107,911,751...107,988,821
Ensembl chr 6:111,951,726...111,979,329

positive regulation of atrial cardiac muscle cell action potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TRPM4

transient receptor potential cation channel subfamily M member 4

NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464

positive regulation of barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARPC2

actin related protein 2/3 complex subunit 2

NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643

cofilin 1

NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806

positive regulation of cardiac muscle cell contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1H

calcium voltage-gated channel subunit alpha1 H

Ensembl chr16:1,195,364...1,222,917

STRIT1

small transmembrane regulator of ion transport 1

involved_in

(MGI:6304509|PMID:30299255)

PMID:30299255

MGI:6304509

NCBI chr 3:152,346,768...152,351,244
Ensembl chr 3:160,399,367...160,402,051

positive regulation of hepatic stellate cell contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTA2

actin alpha 2, smooth muscle

NCBI chr10:85,660,983...85,678,729
Ensembl chr10:89,164,344...89,182,080

positive regulation of myofibroblast contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PTGER3

prostaglandin E receptor 3

NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063

ZEB2

zinc finger E-box binding homeobox 2

NCBI chr2B:15,325,094...15,460,908
Ensembl chr2B:148,460,904...148,596,500

positive regulation of sarcomere organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP10

bone morphogenetic protein 10

involved_in

GO_REF:0000107

NCBI chr2A:68,901,944...68,912,559
Ensembl chr2A:70,023,655...70,034,420

EDN1

endothelin 1

involved_in

GO_REF:0000107

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

EP300

E1A binding protein p300

NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604

MYLK3

myosin light chain kinase 3

involved_in

PMID:17885681

NCBI chr16:26,966,653...27,029,413
Ensembl chr16:45,863,863...45,905,082

PROX1

prospero homeobox 1

involved_in

GO_REF:0000107

NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763

positive regulation of stress fiber assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941

APOA1

apolipoprotein A1

involved_in

GO_REF:0000107

NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122

ARHGEF10

Rho guanine nucleotide exchange factor 10

involved_in

GO_REF:0000107

NCBI chr 8:5,381,357...5,541,094
Ensembl chr 8:1,724,413...1,862,917

ARHGEF10L

Rho guanine nucleotide exchange factor 10 like

involved_in

GO_REF:0000107

NCBI chr 1:16,486,514...16,644,724
Ensembl chr 1:17,580,389...17,697,195

ARHGEF15

Rho guanine nucleotide exchange factor 15

involved_in

PMID:12775584

NCBI chr17:43,336,764...43,349,787
Ensembl chr17:48,070,223...48,082,499

ARHGEF5

Rho guanine nucleotide exchange factor 5

involved_in

GO_REF:0000107

NCBI chr 7:136,069,598...136,094,866
Ensembl chr 7:148,558,803...148,584,078

BAG4

BAG cochaperone 4

involved_in

(MGI:5292318|PMID:21712384)

PMID:21712384

MGI:5292318

NCBI chr 8:37,479,231...37,515,303
Ensembl chr 8:34,656,000...34,692,666

BRAF

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within

(MGI:3047520|PMID:15199148)

PMID:15199148

MGI:3047520

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

capping protein regulator and myosin 1 linker 1

involved_in

GO_REF:0000107

NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092

CCDC88A

coiled-coil domain containing 88A

involved_in

GO_REF:0000107

NCBI chr2A:55,445,060...55,576,479
Ensembl chr2A:56,589,221...56,715,362

CCN2

cellular communication network factor 2

involved_in

GO_REF:0000107

NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077

CD47

CD47 molecule

involved_in

PMID:12023387

NCBI chr 3:105,170,246...105,217,603
Ensembl chr 3:112,104,037...112,143,522

cell division cycle 42

involved_in

(PMID:26051942), (PMID:8625410)

PMID:8625410 PMID:26051942

NCBI chr 1:21,245,970...21,286,210

EPHA1

EPH receptor A1

involved_in

GO_REF:0000107

NCBI chr 7:135,385,894...135,403,632
Ensembl chr 7:147,875,363...147,892,745

EVL

Enah/Vasp-like

involved_in

GO_REF:0000107

NCBI chr14:80,594,889...80,767,652
Ensembl chr14:100,005,645...100,084,598

FERMT2

FERM domain containing kindlin 2

involved_in

GO_REF:0000107

NCBI chr14:33,453,983...33,547,721
Ensembl chr14:51,737,188...51,829,766

FHOD1

formin homology 2 domain containing 1

involved_in

GO_REF:0000107

NCBI chr16:47,574,949...47,593,022
Ensembl chr16:66,963,790...66,981,896

GPR65

G protein-coupled receptor 65

involved_in

GO_REF:0000107

NCBI chr14:68,617,219...68,624,158
Ensembl chr14:87,983,034...87,984,047

ITGB1BP1

integrin subunit beta 1 binding protein 1

involved_in

(MGI:5486551|PMID:17654484)

PMID:17654484

MGI:5486551

NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155

KISS1 receptor

NCBI chr19:211,563...215,332

LIMCH1

LIM and calponin homology domains 1

involved_in

(PMID:28228547)

PMID:28228547

NCBI chr 4:35,685,904...36,025,582
Ensembl chr 4:41,533,560...41,873,694

LIMK1

LIM domain kinase 1

acts_upstream_of_or_within
involved_in

(MGI:3047520|PMID:15199148)

PMID:15199148

GO_REF:0000107 MGI:3047520

Ensembl chr 7:81,231,876...81,271,282

LPAR1

lysophosphatidic acid receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:82,013,960...82,179,227
Ensembl chr 9:110,179,600...110,279,038

MTOR

mechanistic target of rapamycin kinase

acts_upstream_of_or_within
involved_in

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

MYOC

myocilin

involved_in

GO_REF:0000107

NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628

NF2

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

involved_in

GO_REF:0000107

NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013

NADPH oxidase 4

NCBI chr11:84,330,362...84,496,755

NRP1

neuropilin 1

involved_in

GO_REF:0000107

NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648

PAK1

p21 (RAC1) activated kinase 1

involved_in

GO_REF:0000107

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

PDLIM4

PDZ and LIM domain 4

involved_in

PMID:14729062
PMID:22659164

PMID:14729062 PMID:22659164

RGD:1300470 RGD:13432282

NCBI chr 5:127,680,339...127,696,172
Ensembl chr 5:133,843,313...133,857,935

profilin 1

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

profilin 2

involved_in

(PMID:23153535)
(MGI:5545940|PMID:23153535)

MGI:5545940

NCBI chr 3:146,986,364...146,992,558

PPM1E

protein phosphatase, Mg2+/Mn2+ dependent 1E

involved_in

GO_REF:0000107

NCBI chr17:52,832,291...53,057,157
Ensembl chr17:57,874,629...57,903,205

PPM1F

protein phosphatase, Mg2+/Mn2+ dependent 1F

involved_in

GO_REF:0000107

NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128

PRKCQ

protein kinase C theta

NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900

PXN

paxillin

involved_in

(PMID:24863063)

PMID:24863063

NCBI chr12:117,785,614...117,840,816
Ensembl chr12:121,160,295...121,176,667

RAC1

Rac family small GTPase 1

involved_in

PMID:8625410 PMID:23129259

(PMID:23129259)
(PMID:8625410)

UniProt
CAFA

NCBI chr 7:7,039,379...7,068,866

RAPGEF3

Rap guanine nucleotide exchange factor 3

involved_in

GO_REF:0000107

NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252

RGCC

regulator of cell cycle

involved_in

GO_REF:0000107

NCBI chr13:22,639,289...22,652,594
Ensembl chr13:41,228,643...41,241,909

ras homolog family member A

acts_upstream_of_or_within
involved_in

(MGI:6316493|PMID:25071083)
(PMID:15467718)

PMID:15467718 PMID:25071083

GO_REF:0000107 MGI:6316493

NCBI chr 3:49,282,009...49,339,887

RHOC

ras homolog family member C

involved_in

GO_REF:0000107

NCBI chr 1:115,353,868...115,360,036
Ensembl chr 1:124,993,063...125,001,708

ROCK2

Rho associated coiled-coil containing protein kinase 2

involved_in

GO_REF:0000107

NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986

S100A10

S100 calcium binding protein A10

involved_in

GO_REF:0000107

NCBI chr 1:127,341,974...127,353,054
Ensembl chr 1:130,985,312...130,995,130

syndecan 4

NCBI chr20:41,656,406...41,679,549
Ensembl chr20:42,746,281...42,769,737

SERPINF2

serpin family F member 2

involved_in

GO_REF:0000107

NCBI chr17:1,725,469...1,738,887
Ensembl chr17:1,618,549...1,631,570

SH3PXD2B

SH3 and PX domains 2B

involved_in

(MGI:5800302|PMID:27711054)

PMID:27711054

MGI:5800302

NCBI chr 5:167,678,633...167,807,960
Ensembl chr 5:174,591,759...174,719,957

SMAD3

SMAD family member 3

during transdifferentiation

PMID:15987742

RGD:2300418

NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185

SORBS3

sorbin and SH3 domain containing 3

involved_in

GO_REF:0000107

NCBI chr 8:21,794,805...21,825,675
Ensembl chr 8:18,733,776...18,763,861

SYNPO2L

synaptopodin 2 like

involved_in

(MGI:6102963|PMID:29206857)

PMID:29206857

MGI:6102963

NCBI chr10:70,192,289...70,204,008
Ensembl chr10:72,648,952...72,660,184

TAC1

tachykinin precursor 1

NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389

TACR1

tachykinin receptor 1

NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018

TESK1

testis associated actin remodelling kinase 1

involved_in

PMID:18216281

NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545

TGFB3

transforming growth factor beta 3

involved_in

GO_REF:0000107

NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412

TGFBR1

transforming growth factor beta receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748

TPM1

tropomyosin 1

involved_in

PMID:15897890

NCBI chr15:41,989,239...42,018,520
Ensembl chr15:60,286,587...60,315,530

TSC1

TSC complex subunit 1

NCBI chr 9:104,007,708...104,060,938
Ensembl chr 9:132,638,003...132,675,759

WNT11

Wnt family member 11

involved_in

GO_REF:0000107

NCBI chr11:71,239,781...71,263,915
Ensembl chr11:74,540,169...74,560,024

WNT4

Wnt family member 4

involved_in

GO_REF:0000107

NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801

regulation of actin cytoskeleton organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

acts_upstream_of_or_within
involved_in

(MGI:4840122|PMID:20980600)
(MGI:1327082|PMID:9883720)

PMID:9883720 PMID:20980600

GO_REF:0000107 MGI:1327082 MGI:4840122

NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941

ACTR3

actin related protein 3

positive regulation

NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729

ARHGAP18

Rho GTPase activating protein 18

involved_in

GO_REF:0000107

NCBI chr 6:127,368,377...127,558,136
Ensembl chr 6:131,477,383...131,609,221

ARHGAP35

Rho GTPase activating protein 35

involved_in

GO_REF:0000107

NCBI chr19:43,850,692...43,994,487
Ensembl chr19:52,435,379...52,521,104

ARHGAP44

Rho GTPase activating protein 44

involved_in

GO_REF:0000107

NCBI chr17:38,657,824...38,859,591
Ensembl chr17:43,357,438...43,453,457

ARHGEF19

Rho guanine nucleotide exchange factor 19

acts_upstream_of_or_within
involved_in

(PMID:20643356)

PMID:20643356

GO_REF:0000107

NCBI chr 1:15,334,564...15,354,061
Ensembl chr 1:16,327,135...16,342,009

ARHGEF5

Rho guanine nucleotide exchange factor 5

involved_in

GO_REF:0000107

NCBI chr 7:136,069,598...136,094,866
Ensembl chr 7:148,558,803...148,584,078

ARPC2

actin related protein 2/3 complex subunit 2

positive regulation

NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643

BAIAP2

BAR/IMD domain containing adaptor protein 2

involved_in

Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr17:75,460,491...75,542,700
Ensembl chr17:81,187,021...81,269,714

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

involved_in

(PMID:19366662)

PMID:19366662

NCBI chr 7:6,158,306...6,230,903
Ensembl chr 7:103,758,479...103,828,874

BCAS3

BCAS3 microtubule associated cell migration factor

involved_in

(MGI:5582152|PMID:22300583)

PMID:22300583

MGI:5582152

NCBI chr17:54,776,768...55,494,917
Ensembl chr17:59,901,453...60,613,732

BST1

bone marrow stromal cell antigen 1

involved_in

GO_REF:0000107

NCBI chr 4:10,154,453...10,183,448
Ensembl chr 4:15,451,958...15,480,195

BST2

bone marrow stromal cell antigen 2

involved_in

PMID:19273615

NCBI chr19:16,890,257...16,892,989
Ensembl chr19:17,863,991...17,866,728

CAPN10

calpain 10

involved_in

GO_REF:0000107

NCBI chr2B:127,838,477...127,851,334
Ensembl chr2B:246,645,630...246,679,169

CCDC88A

coiled-coil domain containing 88A

involved_in

GO_REF:0000107

NCBI chr2A:55,445,060...55,576,479
Ensembl chr2A:56,589,221...56,715,362

CD2AP

CD2 associated protein

acts_upstream_of_or_within
involved_in

(MGI:5297732|PMID:21911934)

PMID:21911934

GO_REF:0000107 MGI:5297732

NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163

cell division cycle 42

involved_in

(PMID:26051942)

PMID:26051942

NCBI chr 1:21,245,970...21,286,210

CDK10

cyclin dependent kinase 10

involved_in

GO_REF:0000107

NCBI chr16:70,445,200...70,455,476
Ensembl chr16:90,109,492...90,119,532

CDK5R1

cyclin dependent kinase 5 regulatory subunit 1

involved_in

GO_REF:0000107

NCBI chr17:24,285,069...24,289,311
Ensembl chr17:24,577,537...24,579,232

CELSR1

cadherin EGF LAG seven-pass G-type receptor 1

acts_upstream_of_or_within
involved_in

(MGI:4452277|PMID:20223754)

PMID:20223754

GO_REF:0000107 MGI:4452277

Ensembl chr22:45,428,159...45,604,453

CLASP2

cytoplasmic linker associated protein 2

involved_in

(PMID:24520051)

PMID:24520051

NCBI chr 3:33,418,300...33,640,185
Ensembl chr 3:33,721,153...33,938,560

coronin 1A

involved_in

GO_REF:0000107

Ensembl chr16:30,550,383...30,556,196

CORO2B

coronin 2B

acts_upstream_of_or_within
involved_in

(PMID:29162887)

PMID:29162887

GO_REF:0000107

NCBI chr15:47,536,641...47,685,357
Ensembl chr15:66,370,374...66,452,545

CRK

CRK proto-oncogene, adaptor protein

acts_upstream_of_or_within
involved_in

(MGI:4840122|PMID:20980600)

PMID:20980600

GO_REF:0000107 MGI:4840122

NCBI chr17:1,406,335...1,438,587
Ensembl chr17:1,306,509...1,336,569

CSF1R

colony stimulating factor 1 receptor

involved_in

(MGI:5294513|PMID:21610095)

PMID:21610095

MGI:5294513

NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415

CTSL

cathepsin L

acts_upstream_of_or_within

(MGI:5297732|PMID:21911934)

PMID:21911934

MGI:5297732

NCBI chr 9:58,851,899...58,857,170
Ensembl chr 9:86,903,006...86,908,303

DAAM2

dishevelled associated activator of morphogenesis 2

involved_in

GO_REF:0000107

NCBI chr 6:39,374,565...39,488,843
Ensembl chr 6:40,684,695...40,799,395

DAPK3

death associated protein kinase 3

involved_in

(PMID:23454120)

PMID:23454120

NCBI chr19:2,984,806...2,996,782
Ensembl chr19:3,934,496...3,946,011

DIXDC1

DIX domain containing 1

involved_in

GO_REF:0000107

NCBI chr11:106,813,905...106,908,898
Ensembl chr11:110,657,803...110,753,114

DLC1

DLC1 Rho GTPase activating protein

involved_in

GO_REF:0000107

NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233

DMTN

dematin actin binding protein

involved_in

GO_REF:0000107

NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229

EFNA5

ephrin A5

involved_in

GO_REF:0000107

NCBI chr 5:102,732,268...103,026,746
Ensembl chr 5:108,548,927...108,598,942

EPHA3

EPH receptor A3

involved_in

GO_REF:0000107

NCBI chr 3:89,261,166...89,629,010
Ensembl chr 3:91,369,239...91,739,056

EPHA5

EPH receptor A5

involved_in

(MGI:5294297|PMID:17448994)

PMID:17448994

MGI:5294297

NCBI chr 4:58,392,771...58,743,604

ESAM

endothelial cell adhesion molecule

involved_in

GO_REF:0000107

NCBI chr11:119,580,140...119,589,338
Ensembl chr11:123,495,779...123,504,938

EZR

ezrin

NOT|involved_in

(PMID:20551903)

PMID:20551903

NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102

F11R

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890

FAM107A

family with sequence similarity 107 member A

involved_in

GO_REF:0000107

NCBI chr 3:58,494,342...58,557,712
Ensembl chr 3:59,903,602...59,967,013

FSCN1

fascin actin-bundling protein 1

involved_in

(PMID:20137952)

PMID:20137952

NCBI chr 7:5,848,902...5,862,756

FZD10

frizzled class receptor 10

involved_in

(PMID:19137009)

PMID:19137009

NCBI chr12:127,775,141...127,778,420

GPM6B

glycoprotein M6B

involved_in

GO_REF:0000107

NCBI chr X:6,377,913...6,544,826
Ensembl chr X:13,666,192...13,711,964

GRHL3

grainyhead like transcription factor 3

acts_upstream_of_or_within
involved_in

(PMID:20643356)

PMID:20643356

GO_REF:0000107

NCBI chr 1:23,519,911...23,558,105
Ensembl chr 1:24,502,294...24,547,152

HCK

HCK proto-oncogene, Src family tyrosine kinase

involved_in

(PMID:11904303)

PMID:11904303

NCBI chr20:28,346,244...28,395,370
Ensembl chr20:29,474,737...29,523,399

HIP1R

huntingtin interacting protein 1 related

involved_in

GO_REF:0000107

NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726

HRAS

HRas proto-oncogene, GTPase

involved_in

GO_REF:0000107

NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078

HRG

histidine rich glycoprotein

involved_in

GO_REF:0000107

NCBI chr 3:183,701,069...183,712,365
Ensembl chr 3:192,168,299...192,180,539

interleukin 1 alpha

NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801

ILK

integrin linked kinase

positive regulation of alpha smooth muscle actin organization in aging cells

PMID:17234816

RGD:2301768

NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788

IQGAP2

IQ motif containing GTPase activating protein 2

involved_in

(PMID:12515716)

PMID:12515716

NCBI chr 5:38,593,574...38,900,327
Ensembl chr 5:39,138,359...39,516,596

ITGB3

integrin subunit beta 3

involved_in

GO_REF:0000107

NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382

LOC100968722

pyridoxal phosphate phosphatase

involved_in

GO_REF:0000107

NCBI chr22:18,552,737...18,585,014
Ensembl chr22:36,391,200...36,407,938

LOC100977215

uncharacterized LOC100977215

acts_upstream_of_or_within

(MGI:5515359|PMID:12133963)

PMID:12133963

MGI:5515359

NCBI chr 9:34,501,614...34,502,680

LOC100986336

twinfilin-2

involved_in

Ensembl
UniProt

GO_REF:0000107 GO_REF:0000117

NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743

LRP1

LDL receptor related protein 1

involved_in

(MGI:4365879|PMID:19742316)

PMID:19742316

MGI:4365879

NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979

MLST8

MTOR associated protein, LST8 homolog

involved_in

GO_REF:0000107

NCBI chr16:1,063,534...1,067,706
Ensembl chr16:2,306,451...2,310,828

MTOR

mechanistic target of rapamycin kinase

involved_in

GO_REF:0000107

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

MYO1F

myosin IF

acts_upstream_of_or_within

(MGI:3664353|PMID:17023661)

PMID:17023661

MGI:3664353

NCBI chr19:7,807,863...7,858,955
Ensembl chr19:8,656,082...8,705,107

NEDD9

neural precursor cell expressed, developmentally down-regulated 9

involved_in

GO_REF:0000107

NCBI chr 6:11,022,321...11,071,747
Ensembl chr 6:11,297,701...11,420,186

ODAM

odontogenic, ameloblast associated

involved_in

GO_REF:0000107

NCBI chr 4:54,019,039...54,028,085
Ensembl chr 4:60,362,655...60,370,747

PAK1

p21 (RAC1) activated kinase 1

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

PAK3

p21 (RAC1) activated kinase 3

NCBI chr X:100,060,647...100,345,491
Ensembl chr X:110,672,664...110,797,992

PAM

peptidylglycine alpha-amidating monooxygenase

NCBI chr 5:98,104,058...98,385,157
Ensembl chr 5:103,913,456...104,085,774

PDGFRB

platelet derived growth factor receptor beta

involved_in

(MGI:4365879|PMID:19742316)

PMID:19742316

MGI:4365879

NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530

PEAK3

PEAK family member 3

involved_in

GO_REF:0000107

NCBI chr19:1,284,060...1,292,131
Ensembl chr19:2,256,726...2,262,586

PRKCD

protein kinase C delta

involved_in

GO_REF:0000107

NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910

PTK2B

protein tyrosine kinase 2 beta

involved_in

(MGI:3583523|PMID:12960403)

PMID:12960403

MGI:3583523

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

RALA

RAS like proto-oncogene A

involved_in

GO_REF:0000107

NCBI chr 7:44,528,146...44,611,431
Ensembl chr 7:44,559,380...44,580,495

RAPGEF3

Rap guanine nucleotide exchange factor 3

involved_in

PMID:18323524 PMID:21840392

positive regulation
(PMID:21840392)

RGD
UniProt

RGD:9835356

NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252

ras homolog family member A

involved_in

GO_REF:0000107

NCBI chr 3:49,282,009...49,339,887

RHOD

ras homolog family member D

involved_in

(MGI:5512821|PMID:23454120)

PMID:23454120

MGI:5512821

NCBI chr11:62,418,466...62,433,453
Ensembl chr11:65,736,668...65,754,761

RICTOR

RPTOR independent companion of MTOR complex 2

involved_in

GO_REF:0000107

NCBI chr 5:71,299,215...71,435,290
Ensembl chr 5:76,389,130...76,469,830

ROCK1

Rho associated coiled-coil containing protein kinase 1

involved_in

GO_REF:0000107

NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086

ROCK2

Rho associated coiled-coil containing protein kinase 2

involved_in

GO_REF:0000002

NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986

SIGLEC15

sialic acid binding Ig like lectin 15

acts_upstream_of_or_within
involved_in

(MGI:5467208|PMID:22451653)

PMID:22451653

GO_REF:0000107 MGI:5467208

NCBI chr18:39,111,697...39,125,631
Ensembl chr18:42,658,534...42,663,773

SLC4A2

solute carrier family 4 member 2

involved_in

(MGI:5469753|PMID:23341620)

PMID:23341620

MGI:5469753

NCBI chr 7:142,646,413...142,663,376
Ensembl chr 7:154,799,256...154,815,919

SMIM22

small integral membrane protein 22

involved_in

(PMID:29765154)

PMID:29765154

NCBI chr16:3,719,356...3,720,380
Ensembl chr16:4,884,977...4,885,869

STAU2

staufen double-stranded RNA binding protein 2

NCBI chr 8:69,958,735...70,283,591
Ensembl chr 8:71,606,583...71,929,167

TAOK1

TAO kinase 1

involved_in

PMID:18216281

NCBI chr17:27,222,725...27,385,713
Ensembl chr17:27,746,797...27,840,623

TAOK2

TAO kinase 2

involved_in

GO_REF:0000107

Ensembl chr16:30,347,229...30,366,743

TESK1

testis associated actin remodelling kinase 1

involved_in

(MGI:6356246|PMID:30115939)

PMID:30115939

MGI:6356246

NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545

TGFB1

transforming growth factor beta 1

acts_upstream_of_or_within
involved_in

(MGI:5297732|PMID:21911934)

PMID:21911934

GO_REF:0000107 MGI:5297732

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

TGFB2

transforming growth factor beta 2

involved_in

(MGI:5688835|PMID:21984612)

PMID:21984612

MGI:5688835

NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041

twinfilin actin binding protein 1

involved_in

GO_REF:0000117

NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404

VANGL2

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

(MGI:4452277|PMID:20223754)

PMID:20223754

MGI:4452277

NCBI chr 1:135,754,897...135,783,031
Ensembl chr 1:139,683,745...139,704,281

regulation of actin cytoskeleton organization by cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

JAM3

junctional adhesion molecule 3

acts_upstream_of_or_within
involved_in

(MGI:3054279|PMID:15372036)

PMID:15372036

GO_REF:0000107 MGI:3054279

NCBI chr11:128,916,024...129,006,497
Ensembl chr11:132,783,580...132,864,657

regulation of actin cytoskeleton reorganization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARHGDIA

Rho GDP dissociation inhibitor alpha

involved_in

(PMID:8262133)

PMID:8262133

NCBI chr17:76,273,196...76,276,942
Ensembl chr17:81,975,340...81,978,447

ARHGDIB

Rho GDP dissociation inhibitor beta

involved_in

GO_REF:0000107

NCBI chr12:14,944,746...14,964,357
Ensembl chr12:15,341,491...15,361,160

CSF1R

colony stimulating factor 1 receptor

involved_in

GO_REF:0000107

NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415

DAPK3

death associated protein kinase 3

involved_in

GO_REF:0000107

NCBI chr19:2,984,806...2,996,782
Ensembl chr19:3,934,496...3,946,011

ESAM

endothelial cell adhesion molecule

involved_in

(PMID:20298433)

ARUK-UCL

PMID:20298433

NCBI chr11:119,580,140...119,589,338
Ensembl chr11:123,495,779...123,504,938

F11R

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890

IQGAP2

IQ motif containing GTPase activating protein 2

involved_in

GO_REF:0000107

NCBI chr 5:38,593,574...38,900,327
Ensembl chr 5:39,138,359...39,516,596

MDK

midkine

involved_in

GO_REF:0000107

NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254

NOTCH2

notch receptor 2

involved_in

GO_REF:0000107

NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840

PHPT1

phosphohistidine phosphatase 1

involved_in

(PMID:19344975)

PMID:19344975

NCBI chr 9:107,906,160...107,908,130

PTK2B

protein tyrosine kinase 2 beta

involved_in

GO_REF:0000107

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

RAPGEF3

Rap guanine nucleotide exchange factor 3

involved_in

GO_REF:0000107

NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252

RHOD

ras homolog family member D

involved_in

(MGI:5512821|PMID:23454120)

PMID:23454120

MGI:5512821

NCBI chr11:62,418,466...62,433,453
Ensembl chr11:65,736,668...65,754,761

SEMA3E

semaphorin 3E

involved_in

GO_REF:0000107

NCBI chr 7:75,329,049...75,612,946
Ensembl chr 7:88,995,049...89,274,241

TRPM2

transient receptor potential cation channel subfamily M member 2

involved_in

GO_REF:0000107

NCBI chr21:30,606,825...30,737,313
Ensembl chr21:43,903,811...44,035,298

regulation of actin filament bundle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FLNA

filamin A

involved_in

(MGI:4838360|PMID:20713593)

PMID:20713593

MGI:4838360

NCBI chr X:143,799,088...143,825,282

RDX

radixin

involved_in

GO_REF:0000107

NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557

regulation of actin filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LOC100968722

pyridoxal phosphate phosphatase

involved_in

GO_REF:0000107

NCBI chr22:18,552,737...18,585,014
Ensembl chr22:36,391,200...36,407,938

WDR1

WD repeat domain 1

involved_in

GO_REF:0000107

NCBI chr 4:4,487,054...4,516,732
Ensembl chr 4:9,805,164...9,848,032

regulation of actin filament length

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EPS8

epidermal growth factor receptor pathway substrate 8

involved_in

GO_REF:0000107

NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117

MYO3A

myosin IIIA

acts_upstream_of_or_within

(MGI:5766107|PMID:26754646)

PMID:26754646

MGI:5766107

NCBI chr10:26,104,588...26,389,942
Ensembl chr10:26,469,742...26,754,989

MYO3B

myosin IIIB

acts_upstream_of_or_within

(MGI:5766107|PMID:26754646)

PMID:26754646

MGI:5766107

NCBI chr2B:57,458,046...57,940,039
Ensembl chr2B:174,975,796...175,398,203

regulation of actin filament organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C9orf72

C9orf72-SMCR8 complex subunit

involved_in

GO_REF:0000107

NCBI chr 9:27,395,054...27,422,282
Ensembl chr 9:28,001,813...28,022,066

CSF3

colony stimulating factor 3

involved_in

GO_REF:0000107

NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729

GJA1

gap junction protein alpha 1

NCBI chr 6:119,213,513...119,227,617

HAX1

HCLS1 associated protein X-1

involved_in

GO_REF:0000107

NCBI chr 1:129,627,564...129,630,920
Ensembl chr 1:133,241,077...133,244,431

profilin 1

involved_in

GO_REF:0000117

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977

RGS4

regulator of G protein signaling 4

NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225

regulation of actin filament polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABITRAM

actin binding transcription modulator

involved_in

GO_REF:0000107

NCBI chr 9:80,085,138...80,101,685
Ensembl chr 9:108,258,285...108,274,538

ARHGAP18

Rho GTPase activating protein 18

involved_in

GO_REF:0000107

NCBI chr 6:127,368,377...127,558,136
Ensembl chr 6:131,477,383...131,609,221

ARPC3

actin related protein 2/3 complex subunit 3

involved_in

GO_REF:0000002

NCBI chr12:108,007,884...108,023,386
Ensembl chr12:111,399,433...111,415,156

ARPC5

actin related protein 2/3 complex subunit 5

involved_in

GO_REF:0000002

NCBI chr 1:159,156,229...159,165,898
Ensembl chr 1:163,311,111...163,323,554

ARPC5L

actin related protein 2/3 complex subunit 5 like

involved_in

GO_REF:0000002

NCBI chr 9:95,989,650...95,998,340
Ensembl chr 9:124,505,769...124,515,396

CLEC2A

C-type lectin domain family 2 member A

acts_upstream_of_or_within

(MGI:3622591|PMID:16143319)

PMID:16143319

MGI:3622591

NCBI chr12:9,959,826...9,981,376
Ensembl chr12:10,195,862...10,229,273

coronin 1A

acts_upstream_of_or_within
involved_in

(MGI:3818245|PMID:18836449)

PMID:18836449

GO_REF:0000107 MGI:3818245

Ensembl chr16:30,550,383...30,556,196

CYFIP1

cytoplasmic FMR1 interacting protein 1

involved_in

GO_REF:0000002

Ensembl chr15:20,462,811...20,573,684

CYFIP2

cytoplasmic FMR1 interacting protein 2

involved_in

GO_REF:0000002

NCBI chr 5:152,667,136...152,796,575
Ensembl chr 5:159,292,029...159,418,077

CYRIA

CYFIP related Rac1 interactor A

involved_in

GO_REF:0000002

NCBI chr2A:16,532,230...16,642,397
Ensembl chr2A:16,660,469...16,728,797

CYRIB

CYFIP related Rac1 interactor B

involved_in

GO_REF:0000002

NCBI chr 8:126,478,020...126,653,936
Ensembl chr 8:129,209,655...129,272,844

DAAM2

dishevelled associated activator of morphogenesis 2

involved_in

GO_REF:0000107

NCBI chr 6:39,374,565...39,488,843
Ensembl chr 6:40,684,695...40,799,395

drebrin 1

NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872

ELN

elastin

acts_upstream_of_or_within

(MGI:3027647|PMID:14614988)

endothelial cell adhesion molecule

involved_in

GO_REF:0000107

NCBI chr11:119,580,140...119,589,338
Ensembl chr11:123,495,779...123,504,938

GBA2

glucosylceramidase beta 2

involved_in

GO_REF:0000107

NCBI chr 9:35,587,876...35,599,971
Ensembl chr 9:36,390,409...36,402,949

HAX1

HCLS1 associated protein X-1

involved_in

GO_REF:0000107

NCBI chr 1:129,627,564...129,630,920
Ensembl chr 1:133,241,077...133,244,431

HCLS1

hematopoietic cell-specific Lyn substrate 1

involved_in

GO_REF:0000107

NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095

LATS1

large tumor suppressor kinase 1

involved_in

GO_REF:0000107

NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276

PAK3

p21 (RAC1) activated kinase 3

involved_in

GO_REF:0000107

NCBI chr X:100,060,647...100,345,491
Ensembl chr X:110,672,664...110,797,992

profilin 2

NCBI chr 3:146,986,364...146,992,558

PIK3R2

phosphoinositide-3-kinase regulatory subunit 2

acts_upstream_of_or_within
involved_in

(MGI:5613738|PMID:25217619)

PMID:25217619

GO_REF:0000107 MGI:5613738

NCBI chr19:17,632,265...17,649,664
Ensembl chr19:18,611,179...18,624,177

PLEKHG2

pleckstrin homology and RhoGEF domain containing G2

involved_in

GO_REF:0000107

NCBI chr19:36,510,855...36,526,623
Ensembl chr19:45,058,562...45,071,940

PPP1R9A

protein phosphatase 1 regulatory subunit 9A

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

PREX1

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

NCBI chr20:44,965,850...45,169,891
Ensembl chr20:46,033,937...46,226,500

RASA1

RAS p21 protein activator 1

involved_in

GO_REF:0000107

NCBI chr 5:27,980,907...28,104,368
Ensembl chr 5:28,115,159...28,240,321

regulation of actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

villin 1

involved_in

GO_REF:0000107

NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550

WASHC5

WASH complex subunit 5

involved_in
acts_upstream_of_or_within

(MGI:5883184|PMID:27390154)

Ensembl
MGI

PMID:27390154

GO_REF:0000107 MGI:5883184

NCBI chr 8:121,710,118...121,777,977
Ensembl chr 8:124,461,424...124,529,262

regulation of actin phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

twinfilin actin binding protein 1

involved_in

GO_REF:0000107

NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404

regulation of actin polymerization or depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARHGAP35

Rho GTPase activating protein 35

involved_in

GO_REF:0000107

NCBI chr19:43,850,692...43,994,487
Ensembl chr19:52,435,379...52,521,104

CIT

citron rho-interacting serine/threonine kinase

NCBI chr12:117,264,627...117,456,069
Ensembl chr12:120,641,747...120,832,511

coronin 1A

acts_upstream_of_or_within
involved_in

(MGI:3654559|PMID:16902139)

PMID:16902139

GO_REF:0000107 MGI:3654559

Ensembl chr16:30,550,383...30,556,196

NAA80

N-alpha-acetyltransferase 80, NatH catalytic subunit

involved_in

GO_REF:0000107

NCBI chr 3:50,225,000...50,228,015
Ensembl chr 3:51,459,748...51,462,764

ras homolog family member A

NCBI chr 3:49,282,009...49,339,887

SWAP70

switching B cell complex subunit SWAP70

involved_in

GO_REF:0000107

NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422

WAS

WASP actin nucleation promoting factor

involved_in

GO_REF:0000107

NCBI chr X:40,982,132...40,989,767
Ensembl chr X:48,842,765...48,850,380

regulation of Arp2/3 complex-mediated actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AP1AR

adaptor related protein complex 1 associated regulatory protein

acts_upstream_of_or_within
involved_in

(MGI:5429457|PMID:22689987)

MGI
Ensembl
InterPro

PMID:22689987

GO_REF:0000002 GO_REF:0000107 MGI:5429457

NCBI chr 4:104,720,583...104,762,097
Ensembl chr 4:115,282,727...115,322,872

ARF1

ADP ribosylation factor 1

involved_in

PMID:23889934

NCBI chr 1:203,484,803...203,501,395
Ensembl chr 1:208,695,615...208,712,105

regulation of atrial cardiac muscle cell action potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANK2

ankyrin 2

involved_in

GO_REF:0000107

NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905

GJA5

gap junction protein alpha 5

involved_in

GO_REF:0000107

NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413

RYR2

ryanodine receptor 2

involved_in

GO_REF:0000107

NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509

regulation of barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MTPN

myotrophin

involved_in

GO_REF:0000107

NCBI chr 7:127,896,148...127,947,122
Ensembl chr 7:140,392,620...140,443,591

regulation of cardiac muscle cell action potential involved in regulation of contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKAP9

A-kinase anchoring protein 9

involved_in

GO_REF:0000107

NCBI chr 7:83,942,590...84,108,648
Ensembl chr 7:97,540,356...97,705,608

ATP2A2

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

involved_in

PMID:9851937

NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923

CAV3

caveolin 3

involved_in

GO_REF:0000107

NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942

FGF13

fibroblast growth factor 13

involved_in

GO_REF:0000107

NCBI chr X:127,764,648...128,353,928
Ensembl chr X:138,023,016...138,103,217

HCN4

hyperpolarization activated cyclic nucleotide gated potassium channel 4

involved_in

GO_REF:0000107

NCBI chr15:52,231,906...52,285,220
Ensembl chr15:70,997,020...71,042,285

RANGRF

RAN guanine nucleotide release factor

involved_in

GO_REF:0000107

NCBI chr17:43,369,556...43,371,025
Ensembl chr17:48,101,744...48,103,394

regulation of cardiac muscle cell contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA1

adenosine A1 receptor

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

ADRB1

adrenoceptor beta 1

PMID:19525381 PMID:22216755

RGD:2317914 RGD:6893639

NCBI chr10:110,642,491...110,646,595

AKAP6

A-kinase anchoring protein 6

involved_in

PMID:11179196

NCBI chr14:12,978,221...13,602,732
Ensembl chr14:31,395,026...31,792,166

ANK2

ankyrin 2

involved_in

GO_REF:0000107

NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905

ATP1A1

ATPase Na+/K+ transporting subunit alpha 1

NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099

ATP1A2

ATPase Na+/K+ transporting subunit alpha 2

NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303

CASQ2

calsequestrin 2

involved_in

PMID:17569730

NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311

FXYD1

FXYD domain containing ion transport regulator 1

NCBI chr19:32,080,180...32,089,141
Ensembl chr19:40,824,448...40,827,039

GATA4

GATA binding protein 4

NCBI chr 8:7,442,921...7,526,731

KCNJ2

potassium inwardly rectifying channel subfamily J member 2

NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129

MYH7B

myosin heavy chain 7B

NCBI chr20:31,284,197...31,330,893
Ensembl chr20:32,428,870...32,455,569

PDE4B

phosphodiesterase 4B

involved_in

GO_REF:0000107

NCBI chr 1:65,038,120...65,620,764
Ensembl chr 1:67,045,911...67,506,291

PDE4D

phosphodiesterase 4D

involved_in

PMID:19801680 PMID:21670503 PMID:21903937

(MGI:5286798|PMID:21670503), (MGI:5442270|PMID:21903937)
PMID:19801680

RGD
BHF-UCL

MGI:5286798 MGI:5442270 RGD:7327160

NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111

PLN

phospholamban

acts_upstream_of_or_within
involved_in

(MGI:3655311|PMID:8620604)

PMID:8620604

GO_REF:0000107 MGI:3655311

NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668

SCN5A

sodium voltage-gated channel alpha subunit 5

acts_upstream_of_or_within
involved_in

(MGI:3695100|PMID:16172272)

PMID:16172272

GO_REF:0000107 MGI:3695100

NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202

SRI

sorcin

involved_in

GO_REF:0000107

NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029

STC1

stanniocalcin 1

involved_in

GO_REF:0000107

NCBI chr 8:23,089,339...23,102,245
Ensembl chr 8:20,023,469...20,036,321

SUMO1

small ubiquitin like modifier 1

involved_in

GO_REF:0000107

NCBI chr2B:89,461,773...89,493,879
Ensembl chr2B:207,613,654...207,645,590

regulation of cytokinesis, actomyosin contractile ring assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ECT2

epithelial cell transforming 2

involved_in

GO_REF:0000002

NCBI chr 3:169,756,885...169,828,087
Ensembl chr 3:177,938,164...178,008,381

regulation of muscle filament sliding

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYLK2

myosin light chain kinase 2

involved_in

GO_REF:0000107

NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508

regulation of muscle filament sliding speed

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNNC1

troponin C1, slow skeletal and cardiac type

involved_in

GO_REF:0000107

NCBI chr 3:52,393,106...52,396,076
Ensembl chr 3:53,621,749...53,624,726

TNNT2

troponin T2, cardiac type

involved_in

PMID:10747195

NCBI chr 1:176,957,298...176,976,033

regulation of myofibroblast contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PDPN

podoplanin

involved_in

(MGI:5644359|PMID:25347465)

PMID:25347465

MGI:5644359

NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584

regulation of myosin II filament organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTR3

actin related protein 3

NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729

DAPK3

death associated protein kinase 3

involved_in

GO_REF:0000107

NCBI chr19:2,984,806...2,996,782
Ensembl chr19:3,934,496...3,946,011

regulation of sarcomere organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKAP13

A-kinase anchoring protein 13

involved_in

(MGI:5308772|PMID:20139090)

PMID:20139090

MGI:5308772

NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362

ANKRD23

ankyrin repeat domain 23

acts_upstream_of_or_within
involved_in

(MGI:3760007|PMID:17392382)

PMID:17392382

GO_REF:0000107 MGI:3760007

NCBI chr2A:102,469,784...102,476,991
Ensembl chr2A:97,756,775...97,763,360

HDAC2

histone deacetylase 2

acts_upstream_of_or_within

(MGI:3711360|PMID:17322895)

PMID:17322895

MGI:3711360

NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004

MEF2C

myocyte enhancer factor 2C

acts_upstream_of_or_within

(MGI:3768576|PMID:17875930)

PMID:17875930

MGI:3768576

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

regulation of stress fiber assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTG1

actin gamma 1

involved_in

GO_REF:0000107

NCBI chr17:75,965,911...75,968,822
Ensembl chr17:81,668,221...81,671,087

ALMS1

ALMS1 centrosome and basal body associated protein

acts_upstream_of_or_within
involved_in

(PMID:22693585)

PMID:22693585

GO_REF:0000107

NCBI chr2A:73,438,657...73,671,313
Ensembl chr2A:74,926,650...75,152,139

ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

involved_in

GO_REF:0000107

NCBI chr 1:22,620,812...22,676,755
Ensembl chr 1:23,606,579...23,662,472

BBS4

Bardet-Biedl syndrome 4

acts_upstream_of_or_within
involved_in

(MGI:5510934|PMID:23716571)

GO_REF:0000107 MGI:5510934

NCBI chr15:51,601,526...51,656,460
Ensembl chr15:70,362,261...70,416,964

cell division cycle 42

involved_in

(PMID:8625410)

PMID:8625410

NCBI chr 1:21,245,970...21,286,210

FHOD1

formin homology 2 domain containing 1

involved_in

GO_REF:0000107

NCBI chr16:47,574,949...47,593,022
Ensembl chr16:66,963,790...66,981,896

LOC100970287

synaptopodin

involved_in

(MGI:3577135|PMID:15841212)

PMID:15841212

MGI:3577135

NCBI chr 5:146,048,956...146,083,490
Ensembl chr 5:152,046,207...152,085,595

MKKS

MKKS centrosomal shuttling protein

acts_upstream_of_or_within
involved_in

(MGI:5510934|PMID:23716571)

GO_REF:0000107 MGI:5510934

NCBI chr20:10,346,252...10,380,180
Ensembl chr20:10,351,309...10,366,863

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

acts_upstream_of_or_within
involved_in

(MGI:5613738|PMID:25217619)

PMID:25217619

GO_REF:0000107 MGI:5613738

NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960

PIK3R2

phosphoinositide-3-kinase regulatory subunit 2

acts_upstream_of_or_within
involved_in

(MGI:5613738|PMID:25217619)

PMID:25217619

GO_REF:0000107 MGI:5613738

NCBI chr19:17,632,265...17,649,664
Ensembl chr19:18,611,179...18,624,177

PTGER4

prostaglandin E receptor 4

involved_in

GO_REF:0000107

NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148

RAC1

Rac family small GTPase 1

involved_in

(PMID:8625410)

PMID:8625410

NCBI chr 7:7,039,379...7,068,866

TSC1

TSC complex subunit 1

involved_in

GO_REF:0000107

NCBI chr 9:104,007,708...104,060,938
Ensembl chr 9:132,638,003...132,675,759

TTC8

tetratricopeptide repeat domain 8

acts_upstream_of_or_within
involved_in

(MGI:5510934|PMID:23716571)

GO_REF:0000107 MGI:5510934

NCBI chr14:69,446,355...69,502,351
Ensembl chr14:88,802,812...88,857,055

WAS

WASP actin nucleation promoting factor

involved_in

GO_REF:0000107

NCBI chr X:40,982,132...40,989,767
Ensembl chr X:48,842,765...48,850,380

regulation of ventricular cardiac muscle cell action potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1C

calcium voltage-gated channel subunit alpha1 C

involved_in

GO_REF:0000107

NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826

CAV1

caveolin 1

involved_in

GO_REF:0000107

NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655

CTNNA3

catenin alpha 3

involved_in

GO_REF:0000107

NCBI chr10:62,388,454...64,177,116
Ensembl chr10:64,712,576...66,442,238

DLG1

discs large MAGUK scaffold protein 1

involved_in

GO_REF:0000107

NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987

DSC2

desmocollin 2

involved_in

GO_REF:0000107

NCBI chr18:24,296,505...24,332,997
Ensembl chr18:27,894,603...27,930,843

DSG2

desmoglein 2

involved_in

(PMID:16505173), (PMID:23381804)

PMID:16505173 PMID:23381804

NCBI chr18:24,716,181...24,766,837
Ensembl chr18:28,313,223...28,363,786

DSP

desmoplakin

involved_in

GO_REF:0000107

NCBI chr 6:7,381,046...7,426,408
Ensembl chr 6:7,664,211...7,709,391

JUP

junction plakoglobin

involved_in

GO_REF:0000107

NCBI chr17:15,527,115...15,559,251
Ensembl chr17:15,747,163...15,777,479

PKP2

plakophilin 2

involved_in

GO_REF:0000107

NCBI chr12:53,322,227...53,428,747
Ensembl chr12:55,925,174...56,030,998

RYR2

ryanodine receptor 2

involved_in

GO_REF:0000107

NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509

TRPM4

transient receptor potential cation channel subfamily M member 4

involved_in

GO_REF:0000107

NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464

sequestering of actin monomers

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

gelsolin

involved_in

GO_REF:0000107

NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831

SCIN

scinderin

involved_in

GO_REF:0000107

NCBI chr 7:13,269,361...13,351,854
Ensembl chr 7:12,613,996...12,696,244

TMSB4X

thymosin beta 4 X-linked

involved_in

(PMID:1447300), (PMID:1999398)

PMID:1447300 PMID:1999398

NCBI chr X:5,587,242...5,589,417

twinfilin actin binding protein 1

involved_in