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ONTOLOGY REPORT - ANNOTATIONS


Term:collagen metabolic process
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Accession:GO:0032963 term browser browse the term
Definition:The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
Synonyms:exact_synonym: collagen metabolism



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collagen metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A2 collagen type I alpha 2 chain involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5468210|PMID:22910579) Ensembl
Ensembl
MGI
PMID:22910579 GO_REF:0000107 MGI:5468210 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in ISS
IEA
(PMID:18037992) BHF-UCL
BHF-UCL
Ensembl
PMID:18037992 GO_REF:0000107 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein acts_upstream_of_or_within ISO (MGI:3759000|PMID:17717145) MGI PMID:17717145 MGI:3759000 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
JBrowse link
G MIR21 microRNA 21 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3796378|PMID:16969386) MGI
Ensembl
Ensembl
PMID:16969386 GO_REF:0000107 MGI:3796378 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G P3H1 prolyl 3-hydroxylase 1 involved_in ISS
IEA
IBA
(PMID:15044469)
(PMID:21873635)
UniProt
UniProt
InterPro
GO_Central
GO_Central
InterPro
PMID:15044469 PMID:21873635 GO_REF:0000002 NCBI chr 1:42,746,374...42,767,028
Ensembl chr 1:42,746,335...42,767,084
JBrowse link
G P3H2 prolyl 3-hydroxylase 2 involved_in IDA
IBA
IEA
(PMID:18487197)
(PMID:21873635)
UniProt
UniProt
GO_Central
Ensembl
InterPro
GO_Central
InterPro
PMID:18487197 PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:189,956,728...190,122,278
Ensembl chr 3:189,956,728...190,122,437
JBrowse link
G P3H3 prolyl 3-hydroxylase 3 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr12:6,828,407...6,839,847
Ensembl chr12:6,828,407...6,839,847
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5804716|PMID:27435297) Ensembl
Ensembl
MGI
PMID:27435297 GO_REF:0000107 MGI:5804716 NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
JBrowse link
G PRKCD protein kinase C delta ISO RGD PMID:17728702 RGD:1642520 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5468210|PMID:22910579) Ensembl
Ensembl
MGI
PMID:22910579 GO_REF:0000107 MGI:5468210 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:5688831|PMID:22960625) BHF-UCL PMID:22960625 MGI:5688831 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TNS2 tensin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3761416|PMID:10823724) Ensembl
Ensembl
MGI
PMID:10823724 GO_REF:0000107 MGI:3761416 NCBI chr12:53,046,991...53,064,379
Ensembl chr12:53,046,969...53,064,379
JBrowse link
G TNXB tenascin XB involved_in IMP (PMID:15102077) UniProt
UniProt
PMID:15102077 NCBI chr 6:32,041,153...32,109,338
Ensembl chr 6:32,041,153...32,115,334
JBrowse link
G VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog acts_upstream_of_or_within
involved_in
IMP
IEA
(PMID:27435297) MGI
MGI
Ensembl
PMID:27435297 GO_REF:0000107 NCBI chr14:77,426,675...77,457,601
Ensembl chr14:77,426,675...77,457,952
JBrowse link
G VPS33B VPS33B late endosome and lysosome associated acts_upstream_of_or_within
involved_in
IMP
IEA
(PMID:27435297) MGI
Ensembl
MGI
PMID:27435297 GO_REF:0000107 NCBI chr15:90,998,416...91,022,621
Ensembl chr15:90,998,673...91,022,603
JBrowse link
collagen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 involved_in IDA (PMID:11408482) BHF-UCL
BHF-UCL
PMID:11408482 NCBI chr 4:72,280,969...72,569,221
Ensembl chr 4:72,280,969...72,569,221
JBrowse link
G ARG1 arginase 1 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:20107769 GO_REF:0000107 RGD:4143276 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in IMP (PMID:15095409) UniProt
UniProt
PMID:15095409 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL5A1 collagen type V alpha 1 chain involved_in IMP (PMID:11278977), (PMID:15095409) UniProt
UniProt
PMID:11278977 PMID:15095409 NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
JBrowse link
G P3H3 prolyl 3-hydroxylase 3 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr12:6,828,407...6,839,847
Ensembl chr12:6,828,407...6,839,847
JBrowse link
G P3H4 prolyl 3-hydroxylase family member 4 (inactive) involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr17:41,801,953...41,811,949
Ensembl chr17:41,801,947...41,812,604
JBrowse link
G PCOLCE procollagen C-endopeptidase enhancer involved_in TAS (PMID:7523404) PINC PMID:7523404 NCBI chr 7:100,602,363...100,608,175
Ensembl chr 7:100,602,363...100,608,175
JBrowse link
G RCN3 reticulocalbin 3 involved_in IMP (PMID:28939891) UniProt
UniProt
PMID:28939891 NCBI chr19:49,528,003...49,543,633
Ensembl chr19:49,528,003...49,546,962
JBrowse link
G SERPINH1 serpin family H member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1890100|PMID:10995453) Ensembl
Ensembl
MGI
PMID:10995453 GO_REF:0000107 MGI:1890100 NCBI chr11:75,562,253...75,572,783
Ensembl chr11:75,562,056...75,572,783
JBrowse link
G TRAM2 translocation associated membrane protein 2 involved_in IMP (PMID:14749390) UniProt
UniProt
PMID:14749390 NCBI chr 6:52,497,408...52,577,060
Ensembl chr 6:52,497,408...52,577,060
JBrowse link
collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM15 ADAM metallopeptidase domain 15 involved_in IEA UniProt
UniProt
GO_REF:0000043 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775
JBrowse link
G ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 involved_in IEA UniProt
UniProt
GO_REF:0000043 NCBI chr10:70,672,506...70,762,441
Ensembl chr10:70,672,506...70,762,441
JBrowse link
G ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 involved_in IEA UniProt
UniProt
GO_REF:0000043 NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461
JBrowse link
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 involved_in NAS (PMID:11408482) UniProt
UniProt
PMID:11408482 NCBI chr 4:72,280,969...72,569,221
Ensembl chr 4:72,280,969...72,569,221
JBrowse link
G CTSB cathepsin B involved_in IDA (PMID:22952693) BHF-UCL
BHF-UCL
PMID:22952693 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CTSK cathepsin K involved_in
acts_upstream_of_or_within
IDA
IEA
(PMID:22952693)
(PMID:19834056)
BHF-UCL
MGI
BHF-UCL
Ensembl
MGI
PMID:19834056 PMID:22952693 GO_REF:0000107 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577
JBrowse link
G CTSL cathepsin L involved_in IDA (PMID:10716919), (PMID:22952693) BHF-UCL
BHF-UCL
PMID:10716919 PMID:22952693 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
JBrowse link
G CTSS cathepsin S involved_in IDA (PMID:22952693) BHF-UCL
BHF-UCL
PMID:22952693 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in TAS Reactome
Reactome
Reactome:R-HSA-1442490 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564
JBrowse link
G KLK6 kallikrein related peptidase 6 involved_in NAS (PMID:12878203) UniProt
UniProt
PMID:12878203 NCBI chr19:50,958,631...50,969,591
Ensembl chr19:50,958,631...50,969,673
JBrowse link
G MMP1 matrix metallopeptidase 1 involved_in IBA
IEA
TAS
(PMID:21873635) GO_Central
UniProt
GO_Central
Reactome
Reactome
PMID:21873635 GO_REF:0000043 Reactome:R-HSA-1442490 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP10 matrix metallopeptidase 10 involved_in TAS
IEA
IBA
(PMID:21873635) Reactome
Reactome
UniProt
GO_Central
GO_Central
PMID:21873635 GO_REF:0000043 Reactome:R-HSA-1442490 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP11 matrix metallopeptidase 11 involved_in
acts_upstream_of_or_within
IBA
IEA
TAS
ISO
(PMID:21873635)
(MGI:3822602|PMID:18622425)
GO_Central
UniProt
Ensembl
GO_Central
Reactome
MGI
Reactome
PMID:18622425 PMID:21873635 GO_REF:0000043 GO_REF:0000107 MGI:3822602 Reactome:R-HSA-1442490 NCBI chr22:23,772,849...23,784,316
Ensembl chr22:23,768,226...23,784,316
JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IBA
TAS
(PMID:21873635) GO_Central
Reactome
GO_Central
Reactome
PMID:21873635 Reactome:R-HSA-1442490 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in
acts_upstream_of_or_within
IEA
IDA
IBA
TAS
ISO
(PMID:8576151), (PMID:9065415)
(PMID:21873635)
(MGI:3513736|PMID:15563592)
InterPro
UniProt
Ensembl
InterPro
GO_Central
Reactome
MGI
Reactome
UniProt
GO_Central
PMID:8576151 PMID:9065415 PMID:15563592 PMID:21873635 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 MGI:3513736 Reactome:R-HSA-1442490 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within
TAS
IBA
IEA
ISO
(PMID:21873635)
(MGI:3771253|PMID:18022611)
Reactome
GO_Central
Reactome
Ensembl
MGI
GO_Central
PMID:18022611 PMID:21873635 GO_REF:0000107 MGI:3771253 Reactome:R-HSA-1442490 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G MMP15 matrix metallopeptidase 15 involved_in IBA
TAS
(PMID:21873635) GO_Central
Reactome
GO_Central
Reactome
PMID:21873635 Reactome:R-HSA-1442490 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901
JBrowse link
G MMP16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3771253|PMID:18022611)
GO_Central
UniProt
Ensembl
GO_Central
MGI
PMID:18022611 PMID:21873635 GO_REF:0000043 GO_REF:0000107 MGI:3771253 NCBI chr 8:88,032,011...88,327,483
Ensembl chr 8:88,032,011...88,328,025
JBrowse link
G MMP17 matrix metallopeptidase 17 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr12:131,828,393...131,851,771
Ensembl chr12:131,828,393...131,851,783
JBrowse link
G MMP19 matrix metallopeptidase 19 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
UniProt
PMID:21873635 GO_REF:0000043 NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966
JBrowse link
G MMP2 matrix metallopeptidase 2 involved_in
acts_upstream_of_or_within
TAS
IEA
IBA
ISO
(PMID:21873635)
(MGI:3710444|PMID:17440987)
Reactome
UniProt
GO_Central
Ensembl
Reactome
MGI
RGD
GO_Central
PMID:17440987 PMID:21873635 PMID:22410640 GO_REF:0000043 GO_REF:0000107 MGI:3710444 RGD:7207278 Reactome:R-HSA-1442490 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP20 matrix metallopeptidase 20 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr11:102,576,832...102,625,332
Ensembl chr11:102,576,832...102,625,332
JBrowse link
G MMP21 matrix metallopeptidase 21 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr10:125,766,453...125,775,821
Ensembl chr10:125,753,580...125,775,821
JBrowse link
G MMP23B matrix metallopeptidase 23B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:1,632,173...1,634,654
Ensembl chr 1:1,632,163...1,635,263
JBrowse link
G MMP24 matrix metallopeptidase 24 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:35,226,690...35,276,998
Ensembl chr20:35,226,690...35,276,998
JBrowse link
G MMP25 matrix metallopeptidase 25 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr16:3,046,561...3,060,726
Ensembl chr16:3,046,062...3,060,726
JBrowse link
G MMP26 matrix metallopeptidase 26 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
UniProt
PMID:21873635 GO_REF:0000043 NCBI chr11:4,704,784...4,992,429
Ensembl chr11:4,704,784...4,992,431
JBrowse link
G MMP27 matrix metallopeptidase 27 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
GO_Central
PMID:21873635 GO_REF:0000043 NCBI chr11:102,691,487...102,705,769
Ensembl chr11:102,691,487...102,705,769
JBrowse link
G MMP28 matrix metallopeptidase 28 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:35,756,249...35,795,641
Ensembl chr17:35,756,249...35,795,707
JBrowse link
G MMP3 matrix metallopeptidase 3 involved_in IBA
IEA
TAS
(PMID:21873635) GO_Central
UniProt
GO_Central
Reactome
Reactome
PMID:21873635 GO_REF:0000043 Reactome:R-HSA-1442490 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP7 matrix metallopeptidase 7 involved_in TAS
IEA
IBA
(PMID:21873635) Reactome
UniProt
GO_Central
Reactome
GO_Central
PMID:21873635 GO_REF:0000043 Reactome:R-HSA-1442490 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IBA
TAS
IEA
(PMID:21873635) GO_Central
Reactome
GO_Central
UniProt
Reactome
PMID:21873635 GO_REF:0000043 Reactome:R-HSA-1442490 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050
JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in
acts_upstream_of_or_within
IBA
IEA
TAS
ISO
(PMID:21873635)
(MGI:1096214|PMID:9291580)
GO_Central
GO_Central
InterPro
UniProt
Reactome
Ensembl
MGI
RGD
Reactome
PMID:9291580 PMID:21873635 PMID:22410640 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 MGI:1096214 RGD:7207278 Reactome:R-HSA-1442490 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MRC2 mannose receptor C type 2 involved_in IDA (PMID:12972549) UniProt
UniProt
PMID:12972549 NCBI chr17:62,627,670...62,693,597
Ensembl chr17:62,627,670...62,693,597
JBrowse link
G PEPD peptidase D involved_in IEA UniProt
UniProt
GO_REF:0000043 NCBI chr19:33,386,950...33,521,791
Ensembl chr19:33,386,950...33,521,791
JBrowse link
G PRSS2 serine protease 2 involved_in TAS
IDA
IMP
(PMID:12731883)
(PMID:16192646)
Reactome
UniProt
Reactome
UniProt
PMID:12731883 PMID:16192646 Reactome:R-HSA-1442490 NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564
JBrowse link
G PRTN3 proteinase 3 involved_in IEA UniProt
UniProt
GO_REF:0000043 NCBI chr19:840,999...848,175
Ensembl chr19:840,999...848,175
JBrowse link
G RETREG1 reticulophagy regulator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6790058|PMID:34338405) MGI
Ensembl
PMID:34338405 GO_REF:0000107 MGI:6790058 NCBI chr 5:16,473,053...16,616,997
Ensembl chr 5:16,473,038...16,617,101
JBrowse link
G RETREG2 reticulophagy regulator family member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6790058|PMID:34338405) MGI
Ensembl
PMID:34338405 GO_REF:0000107 MGI:6790058 NCBI chr 2:219,178,275...219,185,475
Ensembl chr 2:219,176,225...219,185,475
JBrowse link
G RETREG3 reticulophagy regulator family member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6790058|PMID:34338405) MGI
Ensembl
PMID:34338405 GO_REF:0000107 MGI:6790058 NCBI chr17:42,579,508...42,609,427
Ensembl chr17:42,579,513...42,610,623
JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in TAS Reactome
Reactome
Reactome:R-HSA-1442490 NCBI chr22:37,065,436...37,110,536
Ensembl chr22:37,065,436...37,109,713
JBrowse link
negative regulation of collagen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO RGD PMID:9535419 RGD:2316149 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:21872885 RGD:7245949 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G CIITA class II major histocompatibility complex transactivator involved_in IC (PMID:19041327) BHF-UCL
BHF-UCL
PMID:19041327 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G CYGB cytoglobin involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:20719976 GO_REF:0000107 RGD:9685174 NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO RGD PMID:25840911 PMID:29656108 RGD:12904676 RGD:150520032 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:15521018 GO_REF:0000107 RGD:15045602 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in ISS
IEA
BHF-UCL
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:27,078,615...27,086,403
Ensembl chr 2:27,078,615...27,086,403
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:19204184 GO_REF:0000107 RGD:9685562 NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309
JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:15980055 RGD:1625201 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:26880260 RGD:13504840 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G IL6 interleukin 6 involved_in IDA (PMID:12419823) BHF-UCL
BHF-UCL
PMID:12419823 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor involved_in IDA (PMID:12419823) BHF-UCL
BHF-UCL
PMID:12419823 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G MIR218-1 microRNA 218-1 involved_in IDA (PMID:19913496) BHF-UCL PMID:19913496 NCBI chr 4:20,528,275...20,528,384
Ensembl chr 4:20,528,275...20,528,384
JBrowse link
G MIR218-2 microRNA 218-2 involved_in IDA (PMID:19913496) BHF-UCL PMID:19913496 NCBI chr 5:168,768,146...168,768,255
Ensembl chr 5:168,768,146...168,768,255
JBrowse link
G MIR29A microRNA 29a involved_in IDA (PMID:20067797) BHF-UCL PMID:20067797 NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810
JBrowse link
G MIR29B1 microRNA 29b-1 involved_in IDA
IGI
(PMID:19913496), (PMID:23221517)
(PMID:22269326)
BHF-UCL PMID:19913496 PMID:22269326 PMID:23221517 NCBI chr 7:130,877,459...130,877,539
Ensembl chr 7:130,877,459...130,877,539
JBrowse link
G MIR29B2 microRNA 29b-2 involved_in IGI
IDA
(PMID:22269326)
(PMID:19913496), (PMID:23221517)
BHF-UCL PMID:19913496 PMID:22269326 PMID:23221517 NCBI chr 1:207,802,443...207,802,523
Ensembl chr 1:207,802,443...207,802,523
JBrowse link
G MIR92A1 microRNA 92a-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr13:91,351,314...91,351,391
Ensembl chr13:91,351,314...91,351,391
JBrowse link
G MIR92A2 microRNA 92a-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr  X:134,169,538...134,169,612
Ensembl chr  X:134,169,538...134,169,612
JBrowse link
G NPPC natriuretic peptide C involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:12746286 GO_REF:0000107 RGD:1580115 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:15980055 RGD:1625201 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:17346664 GO_REF:0000107 RGD:2324888 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:16202214 GO_REF:0000107 RGD:8553021 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:22012077 RGD:9850086 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:22012077 RGD:9850086 NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
JBrowse link
negative regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C involved_in IEP (PMID:10545518) BHF-UCL
BHF-UCL
PMID:10545518 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473
JBrowse link
positive regulation of collagen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:27477354 RGD:151665478 NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078
JBrowse link
G AMELX amelogenin X-linked involved_in ISS (PMID:1734713) BHF-UCL
BHF-UCL
PMID:1734713 NCBI chr  X:11,293,413...11,309,588
Ensembl chr  X:11,293,413...11,300,761
JBrowse link
G ARRB2 arrestin beta 2 involved_in IEA
ISO
Ensembl
RGD
Ensembl
PMID:28274926 GO_REF:0000107 RGD:13506828 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IDA (PMID:17720811) BHF-UCL
BHF-UCL
PMID:17720811 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G CBX8 chromobox 8 ISO RGD PMID:23572236 RGD:9586727 NCBI chr17:79,792,132...79,797,077
Ensembl chr17:79,792,132...79,801,683
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:8663511 RGD:8549527 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCN2 cellular communication network factor 2 involved_in IEA
ISO
Ensembl
RGD
Ensembl
PMID:19570811 GO_REF:0000107 RGD:2314490 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 involved_in IDA (PMID:25310401) UniProt
UniProt
PMID:25310401 NCBI chr11:46,277,662...46,321,409
Ensembl chr11:46,277,662...46,321,409
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 involved_in ISO
IEA
RGD
Ensembl
PMID:24938620 PMID:26674152 GO_REF:0000107 RGD:11554781 RGD:150429973 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405
JBrowse link
G DICER1 dicer 1, ribonuclease III ISO RGD PMID:24337369 RGD:150340618 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G ENG endoglin involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:20156938 GO_REF:0000107 RGD:7257540 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:18292803 RGD:2312266 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G F2 coagulation factor II, thrombin involved_in IDA (PMID:9639571) BHF-UCL
BHF-UCL
PMID:9639571 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IDA (PMID:9639571) BHF-UCL
BHF-UCL
PMID:9639571 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
JBrowse link
G HDAC2 histone deacetylase 2 involved_in IC (PMID:19041327) BHF-UCL
BHF-UCL
PMID:19041327 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G IHH Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1335697|PMID:10208865) Ensembl
Ensembl
MGI
PMID:10208865 GO_REF:0000107 MGI:1335697 NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:20644901 RGD:4889158 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:27477354 RGD:151665478 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G ITGA2 integrin subunit alpha 2 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:10867645 GO_REF:0000107 RGD:2307406 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
JBrowse link
G LARP6 La ribonucleoprotein 6, translational regulator involved_in IMP (PMID:21746880) UniProt
UniProt
PMID:21746880 NCBI chr15:70,829,130...70,854,157
Ensembl chr15:70,829,130...70,854,157
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 ISO RGD PMID:9607192 RGD:10412058 NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509
JBrowse link
G MIR149 microRNA 149 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:240,456,001...240,456,089
Ensembl chr 2:240,456,001...240,456,089
JBrowse link
G MIR21 microRNA 21 ISO RGD PMID:29084974 RGD:41404715 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MKX mohawk homeobox acts_upstream_of_or_within ISO (MGI:4457966|PMID:20498044) MGI PMID:20498044 MGI:4457966 NCBI chr10:27,672,874...27,745,819
Ensembl chr10:27,672,874...27,746,060
JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO RGD PMID:15534927 RGD:11532676 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO RGD PMID:15358192 RGD:10449487 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:15978205 GO_REF:0000107 RGD:2292205 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PRDX5 peroxiredoxin 5 involved_in IDA (PMID:15276323) UniProt
UniProt
PMID:15276323 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
JBrowse link
G RGCC regulator of cell cycle involved_in IDA (PMID:19158077) BHF-UCL
BHF-UCL
PMID:19158077 NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871
JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SCX scleraxis bHLH transcription factor involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:144,266,453...144,268,481
Ensembl chr 8:144,266,453...144,268,481
JBrowse link
G SERPINB7 serpin family B member 7 involved_in IEA
ISO
Ensembl
RGD
Ensembl
PMID:21945418 GO_REF:0000107 RGD:7207383 NCBI chr18:63,753,057...63,805,370
Ensembl chr18:63,752,935...63,805,376
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:15828931 RGD:13208547 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SERPINF2 serpin family F member 2 involved_in IDA
IEA
(PMID:17958745) BHF-UCL
Ensembl
BHF-UCL
Ensembl
PMID:17958745 GO_REF:0000107 NCBI chr17:1,742,871...1,755,265
Ensembl chr17:1,742,836...1,755,265
JBrowse link
G SUCO SUN domain containing ossification factor involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:172,532,349...172,611,833
Ensembl chr 1:172,532,349...172,611,833
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IGI
IEA
IDA
IMP
ISO
(PMID:22269326)
(PMID:19734317), (PMID:22269326), (PMID:25310401)
(PMID:11158066)
BHF-UCL
Ensembl
RGD
BHF-UCL
Ensembl
PMID:11158066 PMID:19734317 PMID:22269326 PMID:25310401 PMID:26923362 GO_REF:0000107 RGD:11073665 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB3 transforming growth factor beta 3 involved_in IMP (PMID:11158066) BHF-UCL
BHF-UCL
PMID:11158066 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
JBrowse link
G UCN urocortin involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:11087261 GO_REF:0000107 RGD:1642796 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:17184580 PMID:18475149 RGD:2306811 RGD:2306814 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512
JBrowse link
G VIM vimentin involved_in IMP (PMID:21746880) UniProt
UniProt
PMID:21746880 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G WNT4 Wnt family member 4 involved_in IDA (PMID:17720811) BHF-UCL
BHF-UCL
PMID:17720811 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
positive regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (MGI:4397742|PMID:19834056) MGI PMID:19834056 MGI:4397742 NCBI chr 4:986,997...1,008,351
Ensembl chr 4:986,997...1,004,564
JBrowse link
G VSIR V-set immunoregulatory receptor involved_in IDA (PMID:20666777) UniProt
UniProt
PMID:20666777 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
positive regulation of collagen metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RETN resistin ISO RGD PMID:20795947 RGD:7207234 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
regulation of collagen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR145 microRNA 145 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAP fibroblast activation protein alpha involved_in IDA (PMID:10455171) UniProt
UniProt
PMID:10455171 NCBI chr 2:162,170,684...162,243,445
Ensembl chr 2:162,170,684...162,245,151
JBrowse link
G ITGB1 integrin subunit beta 1 involved_in IDA (PMID:10455171) UniProt
UniProt
PMID:10455171 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
regulation of collagen metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (MGI:4437389|PMID:20053668) MGI PMID:20053668 MGI:4437389 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G MFAP4 microfibril associated protein 4 involved_in IDA (PMID:22355679) BHF-UCL
BHF-UCL
PMID:22355679 NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19643
    metabolic process 13096
      collagen metabolic process 139
        collagen biosynthetic process + 77
        collagen catabolic process + 46
        negative regulation of collagen metabolic process + 26
        positive regulation of collagen metabolic process + 44
        regulation of collagen metabolic process + 75
paths to the root