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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol trisphosphate biosynthetic process
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Accession:GO:0032959 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
Synonyms:exact_synonym: IP3 biosynthesis;   IP3 biosynthetic process;   inositol trisphosphate anabolism;   inositol trisphosphate biosynthesis;   inositol trisphosphate formation;   inositol trisphosphate synthesis
 narrow_synonym: myo-inositol trisphosphate biosynthetic process


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inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C gamma 1 ISO RGD PMID:16973916 RGD:2299886 NCBI chrNW_004936561:598,372...631,575 JBrowse link
G Plcg2 phospholipase C gamma 2 ISO (MGI:MGI:85738|PMID:9013981) MGI PMID:9013981 MGI:MGI:85738 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Ptafr platelet activating factor receptor ISO (MGI:MGI:85738|PMID:9013981) MGI PMID:9013981 MGI:MGI:85738 NCBI chrNW_004936474:12,333,905...12,337,140 JBrowse link
G Scp2 sterol carrier protein 2 ISO (PMID:12641450) UniProtKB PMID:12641450 NCBI chrNW_004936522:8,004,503...8,110,995 JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 ISO (PMID:15705806) UniProtKB PMID:15705806 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO (MGI:MGI:5318037|PMID:10493819) BHF-UCL PMID:10493819 MGI:MGI:5318037 NCBI chrNW_004936508:3,928,467...3,983,481 JBrowse link
G Myh9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chrNW_004936492:4,384,215...4,466,229 JBrowse link
G P2ry1 purinergic receptor P2Y1 ISO PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chrNW_004936519:865,756...872,466 JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 ISO (PMID:8670200) ARUK-UCL PMID:8670200 NCBI chrNW_004936498:2,468,020...2,501,344 JBrowse link
G Plcd1 phospholipase C delta 1 ISO RGD PMID:16709602 RGD:2300424 NCBI chrNW_004936473:27,364,404...27,387,337 JBrowse link
G Pou1f1 POU class 1 homeobox 1 ISO (MGI:MGI:2135699|PMID:11371619) MGI PMID:11371619 MGI:MGI:2135699 NCBI chrNW_004936610:2,262,715...2,279,098 JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptk2b protein tyrosine kinase 2 beta ISO (MGI:MGI:3583523|PMID:12960403) UniProtKB PMID:12960403 MGI:MGI:3583523 NCBI chrNW_004936675:216,970...325,670 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    metabolic process 7668
      biosynthetic process 3913
        organic substance biosynthetic process 3831
          organophosphate biosynthetic process 320
            inositol phosphate biosynthetic process 24
              inositol trisphosphate biosynthetic process 12
                negative regulation of inositol trisphosphate biosynthetic process 0
                positive regulation of inositol trisphosphate biosynthetic process 7
                regulation of inositol trisphosphate biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 11998
    metabolic process 7668
      organic substance metabolic process 7372
        organic hydroxy compound metabolic process 390
          organic hydroxy compound biosynthetic process 175
            alcohol biosynthetic process 100
              polyol biosynthetic process 49
                inositol phosphate biosynthetic process 24
                  inositol trisphosphate biosynthetic process 12
                    negative regulation of inositol trisphosphate biosynthetic process 0
                    positive regulation of inositol trisphosphate biosynthetic process 7
                    regulation of inositol trisphosphate biosynthetic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.