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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol trisphosphate biosynthetic process
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Accession:GO:0032959 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
Synonyms:exact_synonym: IP3 biosynthesis;   IP3 biosynthetic process;   inositol trisphosphate anabolism;   inositol trisphosphate biosynthesis;   inositol trisphosphate formation;   inositol trisphosphate synthesis
 narrow_synonym: myo-inositol trisphosphate biosynthetic process


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inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG1 phospholipase C gamma 1 ISO RGD PMID:16973916 RGD:2299886 NCBI chr20:41,137,519...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G PLCG2 phospholipase C gamma 2 IEA Ensembl GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,739,097...81,962,685
JBrowse link
G PTAFR platelet activating factor receptor IEA Ensembl GO_REF:0000107 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936
JBrowse link
G SCP2 sterol carrier protein 2 IDA (PMID:12641450) UniProtKB PMID:12641450 NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 IDA (PMID:15705806) UniProtKB PMID:15705806 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
JBrowse link
G HRH1 histamine receptor H1 ISS BHF-UCL GO_REF:0000024 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISS BHF-UCL GO_REF:0000024 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,277...36,388,067
Ensembl chr22:36,281,277...36,388,067
JBrowse link
G P2RY1 purinergic receptor P2Y1 IEA Ensembl GO_REF:0000107 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 TAS
IDA
(PMID:17410128)
(PMID:8670200)
ARUK-UCL PMID:8670200, PMID:17410128 NCBI chr11:73,264,503...73,298,625
Ensembl chr11:73,264,505...73,298,625
Ensembl chr11:73,264,505...73,298,625
JBrowse link
G PLCD1 phospholipase C delta 1 ISO RGD PMID:16709602 RGD:2300424 NCBI chr 3:38,007,496...38,029,642
Ensembl chr 3:38,007,496...38,029,642
Ensembl chr 3:38,007,496...38,029,642
JBrowse link
G POU1F1 POU class 1 homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTK2B protein tyrosine kinase 2 beta ISS UniProtKB GO_REF:0000024 NCBI chr 8:27,311,478...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      biosynthetic process 6521
        organic substance biosynthetic process 6421
          organophosphate biosynthetic process 627
            inositol phosphate biosynthetic process 34
              inositol trisphosphate biosynthetic process 13
                negative regulation of inositol trisphosphate biosynthetic process 0
                positive regulation of inositol trisphosphate biosynthetic process 8
                regulation of inositol trisphosphate biosynthetic process + 9
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      organic substance metabolic process 11733
        organic hydroxy compound metabolic process 613
          organic hydroxy compound biosynthetic process 273
            alcohol biosynthetic process 162
              polyol biosynthetic process 71
                inositol phosphate biosynthetic process 34
                  inositol trisphosphate biosynthetic process 13
                    negative regulation of inositol trisphosphate biosynthetic process 0
                    positive regulation of inositol trisphosphate biosynthetic process 8
                    regulation of inositol trisphosphate biosynthetic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.