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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol trisphosphate biosynthetic process
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Accession:GO:0032959 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
Synonyms:exact_synonym: IP3 biosynthesis;   IP3 biosynthetic process;   inositol trisphosphate anabolism;   inositol trisphosphate biosynthesis;   inositol trisphosphate formation;   inositol trisphosphate synthesis
 narrow_synonym: myo-inositol trisphosphate biosynthetic process


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inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG1 phospholipase C gamma 1 ISO RGD PMID:16973916 RGD:2299886 NCBI chr20:37,477,077...37,515,854
Ensembl chr20:38,572,709...38,615,145
JBrowse link
G PLCG2 phospholipase C gamma 2 ISO (MGI:MGI:85738|PMID:9013981) MGI PMID:9013981 MGI:MGI:85738 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G PTAFR platelet activating factor receptor ISO (MGI:MGI:85738|PMID:9013981) MGI PMID:9013981 MGI:MGI:85738 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861
JBrowse link
G SCP2 sterol carrier protein 2 ISO (PMID:12641450) UniProtKB PMID:12641450 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO (MGI:MGI:5318037|PMID:10493819) BHF-UCL PMID:10493819 MGI:MGI:5318037 NCBI chr2A:48,808,822...48,879,021 JBrowse link
G LOC100967334 G-protein coupled estrogen receptor 1 ISO (PMID:15705806) UniProtKB PMID:15705806 NCBI chr 7:1,245,873...1,251,915 JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618
JBrowse link
G P2RY1 purinergic receptor P2Y1 ISO PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813
JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 ISO (PMID:8670200) ARUK-UCL PMID:8670200 NCBI chr11:68,341,722...68,375,923
Ensembl chr11:71,594,250...71,595,236
JBrowse link
G PLCD1 phospholipase C delta 1 ISO RGD PMID:16709602 RGD:2300424 NCBI chr 3:37,906,359...37,928,564
Ensembl chr 3:38,189,496...38,206,886
JBrowse link
G POU1F1 POU class 1 homeobox 1 ISO (MGI:MGI:2135699|PMID:11371619) MGI PMID:11371619 MGI:MGI:2135699 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTK2B protein tyrosine kinase 2 beta ISO (MGI:MGI:3583523|PMID:12960403) UniProtKB PMID:12960403 MGI:MGI:3583523 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    metabolic process 7977
      biosynthetic process 4028
        organic substance biosynthetic process 3942
          organophosphate biosynthetic process 322
            inositol phosphate biosynthetic process 25
              inositol trisphosphate biosynthetic process 12
                negative regulation of inositol trisphosphate biosynthetic process 0
                positive regulation of inositol trisphosphate biosynthetic process 7
                regulation of inositol trisphosphate biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 12561
    metabolic process 7977
      organic substance metabolic process 7668
        organic hydroxy compound metabolic process 412
          organic hydroxy compound biosynthetic process 179
            alcohol biosynthetic process 102
              polyol biosynthetic process 49
                inositol phosphate biosynthetic process 25
                  inositol trisphosphate biosynthetic process 12
                    negative regulation of inositol trisphosphate biosynthetic process 0
                    positive regulation of inositol trisphosphate biosynthetic process 7
                    regulation of inositol trisphosphate biosynthetic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.