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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol trisphosphate metabolic process
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Accession:GO:0032957 term browser browse the term
Definition:The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
Synonyms:exact_synonym: IP3 metabolic process;   IP3 metabolism;   inositol trisphosphate metabolism
 narrow_synonym: myo-inositol trisphosphate metabolic process


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inositol trisphosphate metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inppl1 inositol polyphosphate phosphatase-like 1 IDA RGD PMID:12933696 RGD:1626126 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524
JBrowse link
G Ipmk inositol polyphosphate multikinase ISO (PMID:30624931) RGD PMID:30624931 NCBI chr20:18,457,309...18,489,884
Ensembl chr20:18,457,310...18,489,833
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B ISO
ISS
(PMID:1654894)
GO_REF:0000024
RGD
UniProt
PMID:1654894 GO_REF:0000024 NCBI chr13:98,615,287...98,710,426
Ensembl chr13:98,615,287...98,708,149
JBrowse link
G Plcb1 phospholipase C beta 1 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Plcb3 phospholipase C beta 3 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910
JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:16973916 RGD:2299886 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Plcg2 phospholipase C, gamma 2 ISO
IEA
(MGI:MGI:85738|PMID:9013981)
GO_REF:0000107
RGD
Ensembl
PMID:9013981 GO_REF:0000107, MGI:MGI:85738 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Ptafr platelet-activating factor receptor ISO (MGI:MGI:85738|PMID:9013981) RGD PMID:9013981 MGI:MGI:85738 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Scp2 sterol carrier protein 2 ISO (PMID:12641450) RGD PMID:12641450 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IEA
ISO
ISS
GO_REF:0000107
(PMID:15705806)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15705806 GO_REF:0000024, GO_REF:0000107 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO
IEA
(MGI:MGI:5318037|PMID:10493819)
GO_REF:0000107
RGD
Ensembl
PMID:10493819 GO_REF:0000107, MGI:MGI:5318037 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G P2ry1 purinergic receptor P2Y1 IDA PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 ISO (PMID:8670200) RGD PMID:8670200 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Pou1f1 POU class 1 homeobox 1 ISO MGI:MGI:1856024|MGI:MGI:1856025 (MGI:MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:MGI:2135699 NCBI chr11:2,645,659...2,662,581
Ensembl chr11:2,645,865...2,662,579
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptk2b protein tyrosine kinase 2 beta ISO
ISS
(MGI:MGI:3583523|PMID:12960403)
GO_REF:0000024
RGD
UniProt
PMID:12960403 GO_REF:0000024, MGI:MGI:3583523 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        organophosphate metabolic process 971
          inositol phosphate metabolic process 62
            inositol trisphosphate metabolic process 18
              inositol trisphosphate biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        organic hydroxy compound metabolic process 538
          alcohol metabolic process 358
            polyol metabolic process 124
              inositol phosphate metabolic process 62
                inositol trisphosphate metabolic process 18
                  inositol trisphosphate biosynthetic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.