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ONTOLOGY REPORT - ANNOTATIONS

Term:secretion by tissue
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Accession:GO:0032941 term browser browse the term
Definition:The controlled release of a substance by a tissue.
Synonyms:exact_synonym: tissue secretion
 related_synonym: expulsion of gland contents


show annotations for term's descendants           Sort by:
cerebrospinal fluid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEP (PMID:16814974) UniProt PMID:16814974 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G AQP4 aquaporin 4 involved_in ISO (MGI:6277731|PMID:30293570) CACAO PMID:30293570 MGI:6277731 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G CELSR2 cadherin EGF LAG seven-pass G-type receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20473291) Ensembl
MGI		 PMID:20473291 GO_REF:0000107 NCBI chr 1:109,249,539...109,275,751
Ensembl chr 1:109,249,539...109,275,751 		JBrowse link
G SLC4A5 solute carrier family 4 member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21705333) Ensembl
MGI		 PMID:21705333 GO_REF:0000107 NCBI chr 2:74,216,242...74,343,416
Ensembl chr 2:74,216,242...74,343,416 		JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (PMID:10716451) MGI PMID:10716451 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
milk ejection reflex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20089884) Ensembl
MGI		 PMID:20089884 GO_REF:0000107 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15240734)
(PMID:15240734), (PMID:15630442)
(PMID:15630442)		 Ensembl
MGI		 PMID:15240734 PMID:15630442 GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADORA1 adenosine A1 receptor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15630442) Ensembl
MGI		 PMID:15630442 GO_REF:0000107 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G ADORA3 adenosine A3 receptor acts_upstream_of ISO (PMID:15240734) MGI PMID:15240734 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:19359471) UniProt
MGI
Ensembl		 PMID:19359471 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G ANO1 anoctamin 1 involved_in ISS
IMP		 (PMID:33026825) UniProt PMID:33026825 GO_REF:0000024 NCBI chr11:69,965,997...70,189,530
Ensembl chr11:69,985,907...70,189,530 		JBrowse link
G ATG5 autophagy related 5 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:24185898) Ensembl
MGI		 PMID:24185898 GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of ISO (PMID:24185898) MGI PMID:24185898 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in
acts_upstream_of		 IEA
ISO		 (PMID:24185898) Ensembl
MGI		 PMID:24185898 GO_REF:0000107 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:27959908) MGI PMID:27959908 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30233597) Ensembl
MGI		 PMID:30233597 GO_REF:0000107 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:148,451,032...148,654,527
Ensembl chr 5:148,446,042...148,677,235 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta acts_upstream_of ISO (PMID:24185898) MGI PMID:24185898 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming involved_in IMP (PMID:17058067) UniProt PMID:17058067 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G P2RY2 purinergic receptor P2Y2 acts_upstream_of ISO (PMID:17728398) MGI PMID:17728398 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17728398) Ensembl
MGI		 PMID:17728398 GO_REF:0000107 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22419116) Ensembl
MGI		 PMID:22419116 GO_REF:0000107 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G VAMP2 vesicle associated membrane protein 2 NOT|involved_in IMP (PMID:22144578) UniProt PMID:22144578 NCBI chr17:8,159,147...8,162,948
Ensembl chr17:8,159,149...8,163,546 		JBrowse link
G VAMP3 vesicle associated membrane protein 3 NOT|involved_in IMP (PMID:22144578) UniProt PMID:22144578 NCBI chr 1:7,771,296...7,781,432
Ensembl chr 1:7,771,296...7,781,432 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in IMP
IBA		 (PMID:22144578) UniProt
GO_Central		 PMID:22144578 GO_REF:0000033 NCBI chr 2:85,577,586...85,582,031
Ensembl chr 2:85,561,562...85,582,031 		JBrowse link
negative regulation of mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15240734), (PMID:15630442)
(PMID:15630442)		 Ensembl
MGI		 PMID:15240734 PMID:15630442 GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADORA1 adenosine A1 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15630442) Ensembl
MGI		 PMID:15630442 GO_REF:0000107 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
negative regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MADD MAP kinase activating death domain ISO RGD PMID:23702376 RGD:9588639 NCBI chr11:47,269,188...47,330,031
Ensembl chr11:47,269,161...47,330,031 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:167,954,022...168,247,595
Ensembl chr 2:167,954,020...168,247,595 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21317537) Ensembl
MGI		 PMID:21317537 GO_REF:0000107 NCBI chr12:752,579...911,452
Ensembl chr12:752,579...911,452 		JBrowse link
G WNK3 WNK lysine deficient protein kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:54,192,823...54,358,900
Ensembl chr  X:54,192,823...54,358,642 		JBrowse link
G WNK4 WNK lysine deficient protein kinase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21317537) Ensembl
MGI		 PMID:21317537 GO_REF:0000107 NCBI chr17:42,780,610...42,797,066
Ensembl chr17:42,780,610...42,797,066 		JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCANP1 dendritic cell associated nuclear protein 1 involved_in IGI (PMID:23419067) CAFA PMID:23419067 NCBI chr 5:135,444,214...135,447,348
Ensembl chr 5:135,444,214...135,447,348 		JBrowse link
G NEUROG1 neurogenin 1 involved_in IGI (PMID:23419067) CAFA PMID:23419067 NCBI chr 5:135,534,282...135,535,964
Ensembl chr 5:135,534,282...135,535,964 		JBrowse link
G TIFAB TIFA inhibitor involved_in IGI (PMID:23419067) CAFA PMID:23419067 NCBI chr 5:135,444,226...135,452,351
Ensembl chr 5:135,444,226...135,452,351 		JBrowse link
pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IEP (PMID:12801959) UniProt PMID:12801959 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G AQP5 aquaporin 5 involved_in IEP (PMID:12801959) UniProt PMID:12801959 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682 		JBrowse link
G CEL carboxyl ester lipase involved_in IDA
IEA
IBA		 (PMID:1854805) UniProt
TreeGrafter
GO_Central		 PMID:1854805 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861 		JBrowse link
G COPA COPI coat complex subunit alpha acts_upstream_of_or_within IDA (PMID:1429581) MGI PMID:1429581 NCBI chr 1:160,288,594...160,343,250
Ensembl chr 1:160,288,594...160,343,566 		JBrowse link
G SCT secretin involved_in NAS (PMID:11060443) UniProt PMID:11060443 NCBI chr11:626,309...627,181
Ensembl chr11:626,309...627,181 		JBrowse link
positive regulation of mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA3 adenosine A3 receptor acts_upstream_of_or_within ISO (PMID:15240734) MGI PMID:15240734 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in IMP (PMID:22441738) UniProt PMID:22441738 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716 		JBrowse link
G ATG5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24185898) Ensembl
MGI		 PMID:24185898 GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:24185898) MGI PMID:24185898 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24185898) Ensembl
MGI		 PMID:24185898 GO_REF:0000107 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO
IEA		 RGD
Ensembl		 PMID:29183867 GO_REF:0000107 RGD:38676259 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta acts_upstream_of_or_within ISO (PMID:24185898) MGI PMID:24185898 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G P2RY2 purinergic receptor P2Y2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17728398) InterPro
MGI		 PMID:17728398 GO_REF:0000002 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17728398) Ensembl
MGI		 PMID:17728398 GO_REF:0000107 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11991626 PMID:18254372 RGD:10003046 RGD:10003093 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
G SYTL2 synaptotagmin like 2 involved_in ISO (MGI:3693417|PMID:16716193) UniProt PMID:16716193 MGI:3693417 NCBI chr11:85,694,229...85,854,870
Ensembl chr11:85,694,224...85,811,159 		JBrowse link
positive regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VAMP8 vesicle associated membrane protein 8 acts_upstream_of_or_within ISO (PMID:18535671) MGI PMID:18535671 NCBI chr 2:85,577,586...85,582,031
Ensembl chr 2:85,561,562...85,582,031 		JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPR3 natriuretic peptide receptor 3 ISO RGD PMID:12829435 RGD:1581460 NCBI chr 5:32,690,872...32,791,720
Ensembl chr 5:32,689,070...32,791,724 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G SCT secretin involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:11123201 GO_REF:0000033 GO_REF:0000107 RGD:9590235 NCBI chr11:626,309...627,181
Ensembl chr11:626,309...627,181 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:2755938 GO_REF:0000107 RGD:10044250 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671 		JBrowse link
positive regulation of pancreatic trypsinogen secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMP13 matrix metallopeptidase 13 ISO RGD PMID:12771515 RGD:724699 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
positive regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in IMP (PMID:15727941), (PMID:9096382) UniProt PMID:9096382 PMID:15727941 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G NEGR1 neuronal growth regulator 1 acts_upstream_of_or_within ISO (PMID:37216094) MGI PMID:37216094 NCBI chr 1:71,395,943...72,282,539
Ensembl chr 1:71,395,943...72,282,539 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G TAC4 tachykinin precursor 4 acts_upstream_of_or_within ISO (PMID:11062498) MGI PMID:11062498 NCBI chr17:49,838,300...49,848,069
Ensembl chr17:49,838,300...49,848,069 		JBrowse link
regulation of mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24581500) Ensembl
MGI		 PMID:24581500 GO_REF:0000107 NCBI chr11:278,407...285,388
Ensembl chr11:278,407...285,388 		JBrowse link
regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 involved_in IMP (PMID:19102732) UniProt PMID:19102732 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G OPRK1 opioid receptor kappa 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637 		JBrowse link
saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP5 aquaporin 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10400615), (PMID:10795927), (PMID:15647389) Ensembl
MGI		 PMID:10400615 PMID:10795927 PMID:15647389 GO_REF:0000107 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10944224) Ensembl
MGI
InterPro		 PMID:10944224 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO (PMID:16873365) MGI PMID:16873365 NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16873365) Ensembl
MGI		 PMID:16873365 GO_REF:0000107 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G SLC4A9 solute carrier family 4 member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:140,360,194...140,375,141
Ensembl chr 5:140,360,194...140,375,141 		JBrowse link
G STATH statherin involved_in NAS (PMID:1718282) UniProt PMID:1718282 NCBI chr 4:69,995,966...70,002,570
Ensembl chr 4:69,995,966...70,002,570 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 acts_upstream_of_or_within ISO (PMID:17956991) MGI PMID:17956991 NCBI chr 3:142,724,034...142,807,888
Ensembl chr 3:142,724,034...142,807,888 		JBrowse link
tear secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 involved_in IMP (PMID:19102732) UniProt PMID:19102732 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G LACRT lacritin involved_in IDA
NAS		 (PMID:25034600), (PMID:25481446)
(PMID:18840430)		 FlyBase
UniProt		 PMID:18840430 PMID:25034600 PMID:25481446 NCBI chr12:54,630,811...54,634,895
Ensembl chr12:54,630,811...54,634,895 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:42,456,757...42,589,746
Ensembl chr12:42,456,757...42,590,355 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    multicellular organismal process 8456
      secretion by tissue 62
        cerebrospinal fluid secretion 5
        milk ejection reflex 1
        mucus secretion + 25
        pancreatic juice secretion + 16
        saliva secretion + 17
        tear secretion 3
Path 2
Term Annotations click to browse term
  biological_process 19669
    localization 5869
      establishment of localization 5161
        transport 4818
          secretion 1244
            secretion by tissue 62
              cerebrospinal fluid secretion 5
              milk ejection reflex 1
              mucus secretion + 25
              pancreatic juice secretion + 16
              saliva secretion + 17
              tear secretion 3
paths to the root