secretion by cell - Ontology Report

GO_REF:0000107

NCBI chr37:22,136,732...22,306,917
Ensembl chr37:22,138,245...22,405,736

AQP1

aquaporin 1

involved_in
acts_upstream_of_or_within

(MGI:3805139|PMID:18511498)

PMID:18511498

GO_REF:0000107 MGI:3805139

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

AXL

AXL receptor tyrosine kinase

involved_in
acts_upstream_of_or_within

(MGI:3528131|PMID:15650770)

PMID:15650770

GO_REF:0000107 MGI:3528131

NCBI chr 1:112,699,679...112,727,434
Ensembl chr 1:112,700,365...112,726,960

CKLF

chemokine like factor

involved_in

GO_REF:0000107

NCBI chr 5:82,709,791...82,726,866
Ensembl chr 5:82,709,851...82,726,778

FURIN

furin, paired basic amino acid cleaving enzyme

involved_in

GO_REF:0000107

NCBI chr 3:53,357,491...53,368,285
Ensembl chr 3:53,358,045...53,365,423

MERTK

MER proto-oncogene, tyrosine kinase

involved_in
acts_upstream_of_or_within

(MGI:3528131|PMID:15650770)

PMID:15650770

GO_REF:0000107 MGI:3528131

NCBI chr17:36,336,787...36,445,796
Ensembl chr17:36,336,861...36,445,380

PCSK6

proprotein convertase subtilisin/kexin type 6

involved_in

GO_REF:0000107

NCBI chr 3:39,582,804...39,768,838
Ensembl chr 3:39,582,819...39,767,929

SERPINE2

serpin family E member 2

acts_upstream_of_or_within

(MGI:3654805|PMID:16319172)

PMID:16319172

MGI:3654805

NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228

syntaxin 1A

involved_in

(PMID:12130530)

PMID:12130530

NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833

TYRO3

TYRO3 protein tyrosine kinase

involved_in
acts_upstream_of_or_within

(MGI:3528131|PMID:15650770)

PMID:15650770

GO_REF:0000107 MGI:3528131

NCBI chr30:8,571,230...8,602,655
Ensembl chr30:8,571,475...8,598,721

acetylcholine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC44A4

solute carrier family 44 member 4

involved_in

GO_REF:0000107

NCBI chr12:1,328,276...1,340,752
Ensembl chr12:1,328,399...1,340,778

acrosomal vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EQTN

equatorin

acts_upstream_of_or_within
involved_in

(MGI:5293452|PMID:19285662)

MGI
InterPro

PMID:19285662

GO_REF:0000002 MGI:5293452

NCBI chr11:45,417,579...45,431,255

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692

RIMS1

regulating synaptic membrane exocytosis 1

involved_in

GO_REF:0000107

NCBI chr12:34,473,974...34,661,893
Ensembl chr12:34,474,033...34,659,410

SYT6

synaptotagmin 6

involved_in

GO_REF:0000107

NCBI chr17:51,859,564...51,923,044
Ensembl chr17:51,864,774...51,924,676

unc-13 homolog B

involved_in

(PMID:22248876)

PMID:22248876

NCBI chr11:51,707,968...51,941,148
Ensembl chr11:51,708,302...51,940,955

ZP4

zona pellucida glycoprotein 4

involved_in

GO_REF:0000107

NCBI chr 4:2,324,657...2,332,357
Ensembl chr 4:2,324,226...2,331,470

aldosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGT

angiotensinogen

involved_in
acts_upstream_of_or_within

(MGI:5426321|PMID:22550170)
(MGI:3618038|PMID:9557921)

PMID:9557921 PMID:22550170

MGI:3618038 MGI:5426321

NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880

VPS25

vacuolar protein sorting 25 homolog

involved_in

(MGI:5426321|PMID:22550170)

PMID:22550170

MGI:5426321

NCBI chr 9:20,242,230...20,247,396

WNK4

WNK lysine deficient protein kinase 4

involved_in

GO_REF:0000107

NCBI chr 9:20,224,726...20,241,214
Ensembl chr 9:20,157,410...20,241,376

amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKAP5

A-kinase anchoring protein 5

acts_upstream_of_or_within

(MGI:4442128|PMID:20164376)

PMID:20164376

MGI:4442128

NCBI chr 8:38,891,637...38,902,390
Ensembl chr 8:38,896,840...38,898,126

basolateral protein secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC4A8

solute carrier family 4 member 8

involved_in

PMID:21195699

NCBI chr27:3,398,776...3,460,562
Ensembl chr27:3,403,804...3,460,583

basophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PI4K2A

phosphatidylinositol 4-kinase type 2 alpha

NCBI chr28:10,890,654...10,921,898
Ensembl chr28:10,720,094...10,930,286

calcium ion regulated lysosome exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARL8B

ADP ribosylation factor like GTPase 8B

involved_in

GO_REF:0000107

NCBI chr20:12,479,680...12,525,330
Ensembl chr20:12,481,860...12,525,499

SYT11

synaptotagmin 11

involved_in

GO_REF:0000107

NCBI chr 7:41,910,102...41,929,020
Ensembl chr 7:41,912,920...41,929,617

synaptotagmin 7

involved_in

PMID:10725327
(MGI:3690533|PMID:16982801), (MGI:3798323|PMID:18539119)
PMID:11511344

PMID:10725327 PMID:11511344 PMID:16982801 PMID:18539119

MGI:3690533 MGI:3798323 RGD:11041027 RGD:2311145

NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367

calcium ion-regulated exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1A

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

(MGI:1353373|PMID:10670432)

PMID:10670432

MGI:1353373

NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032

DOC2B

double C2 domain beta

involved_in

PMID:17124501 PMID:21873635

GO_REF:0000107

NCBI chr 9:45,450,270...45,488,638
Ensembl chr 9:45,450,302...45,485,247

RIMS1

regulating synaptic membrane exocytosis 1

acts_upstream_of_or_within
involved_in

ISO
IBA

(MGI:3703478|PMID:17124501)
(PMID:21873635)

MGI
GO_Central

MGI:3703478

NCBI chr12:34,473,974...34,661,893
Ensembl chr12:34,474,033...34,659,410

PMID:17124501 PMID:21873635

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within
involved_in

ISO
IBA
IEA

(MGI:3703478|PMID:17124501)
(PMID:21873635)

MGI
GO_Central
InterPro

GO_REF:0000002 MGI:3703478

NCBI chr13:4,928,518...5,499,258
Ensembl chr13:4,927,121...5,496,629

RIMS3

regulating synaptic membrane exocytosis 3

involved_in

(PMID:21873635)

NCBI chr15:2,353,876...2,391,742
Ensembl chr15:2,353,693...2,404,431

SNAP25

synaptosome associated protein 25

NCBI chr24:12,003,005...12,081,385
Ensembl chr24:12,004,117...12,081,329

STX1B

syntaxin 1B

involved_in

GO_REF:0000107

NCBI chr 6:17,209,972...17,219,903
Ensembl chr 6:17,210,433...17,241,363

synaptotagmin 1

acts_upstream_of_or_within
involved_in

PMID:21521611 PMID:21873635

(MGI:5141208|PMID:21521611)
(PMID:21873635)

MGI
Ensembl
GO_Central

GO_REF:0000107 MGI:5141208

NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732

SYT5

synaptotagmin 5

involved_in

(PMID:21873635)

NCBI chr 1:102,456,767...102,463,750
Ensembl chr 1:102,456,782...102,463,749

synaptotagmin 7

involved_in

(MGI:5707519|PMID:26738595)

PMID:26738595

MGI:5707519

NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367

SYT8

synaptotagmin 8

involved_in

(PMID:21873635)

NCBI chr18:46,069,380...46,075,477
Ensembl chr18:46,072,495...46,075,480

calcium-dependent activation of synaptic vesicle fusion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DOC2A

double C2 domain alpha

involved_in

GO_REF:0000107

NCBI chr 6:18,041,551...18,046,779
Ensembl chr 6:18,041,296...18,046,265

DOC2B

double C2 domain beta

involved_in

GO_REF:0000107

NCBI chr 9:45,450,270...45,488,638
Ensembl chr 9:45,450,302...45,485,247

synaptotagmin 1

involved_in

GO_REF:0000107

NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732

SYT2

synaptotagmin 2

involved_in

(MGI:3695515|PMID:17192432)

PMID:17192432

MGI:3695515

NCBI chr 7:497,387...509,338
Ensembl chr 7:497,394...502,952

synaptotagmin 7

involved_in

(MGI:5554634|PMID:24267651)

PMID:24267651

MGI:5554634

NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367

SYT9

synaptotagmin 9

involved_in

(MGI:3714434|PMID:17521570)

PMID:17521570

MGI:3714434

NCBI chr21:30,985,059...31,123,986
Ensembl chr21:30,986,521...31,162,414

calcium-ion regulated exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARHGAP17

Rho GTPase activating protein 17

acts_upstream_of_or_within

PMID:10967100

NCBI chr 6:21,081,965...21,176,685
Ensembl chr 6:21,073,912...21,176,205

CACNA1A

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

(MGI:2180460|PMID:12065603)

PMID:12065603

MGI:2180460

NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

(MGI:2670808|PMID:12881419)

PMID:12881419

MGI:2670808

NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429

CLEC19A

C-type lectin domain containing 19A

involved_in

(PMID:21873635)

NCBI chr 6:26,082,725...26,103,129

CLTRN

collectrin, amino acid transport regulator

acts_upstream_of_positive_effect
involved_in

(PMID:16330323)

PMID:16330323

GO_REF:0000107

NCBI chr X:11,863,479...11,908,361
Ensembl chr X:11,798,839...11,900,594

LOC489080

synaptotagmin 15

involved_in

(PMID:21873635)

NCBI chr 4:34,754,250...34,763,273

NOTCH1

notch receptor 1

acts_upstream_of
involved_in

(MGI:3841508|PMID:19251639)

PMID:19251639

GO_REF:0000107 MGI:3841508

NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277

OLFML1

olfactomedin like 1

involved_in

(PMID:21873635)

NCBI chr21:31,136,218...31,162,405
Ensembl chr21:30,986,521...31,162,414

PPP3CB

protein phosphatase 3 catalytic subunit beta

involved_in

GO_REF:0000107

NCBI chr 4:23,976,023...24,028,139
Ensembl chr 4:23,977,317...24,028,153

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692

RAP1B

RAP1B, member of RAS oncogene family

acts_upstream_of
involved_in

(MGI:5490391|PMID:23616533)

PMID:23616533

GO_REF:0000107 MGI:5490391

NCBI chr10:10,805,359...10,816,839
Ensembl chr10:10,805,357...10,815,575

RAPGEF4

Rap guanine nucleotide exchange factor 4

acts_upstream_of_or_within
involved_in

(MGI:2151174|PMID:11056535)

PMID:11056535

GO_REF:0000107 MGI:2151174

NCBI chr36:17,087,488...17,323,504
Ensembl chr36:17,087,488...17,323,220

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within

(MGI:2151174|PMID:11056535)

PMID:11056535

MGI:2151174

NCBI chr13:4,928,518...5,499,258
Ensembl chr13:4,927,121...5,496,629

RIMS3

regulating synaptic membrane exocytosis 3

NCBI chr15:2,353,876...2,391,742
Ensembl chr15:2,353,693...2,404,431

SDF4

stromal cell derived factor 4

involved_in

(PMID:21873635)

NCBI chr 5:56,407,506...56,421,515
Ensembl chr 5:56,407,807...56,421,430

syntaxin 1A

acts_upstream_of_or_within

(MGI:3703420|PMID:10468580)

PMID:10468580

MGI:3703420

NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833

SYN2

synapsin II

involved_in

GO_REF:0000107

NCBI chr20:6,368,348...6,569,355
Ensembl chr20:6,369,122...6,568,508

synaptotagmin 1

involved_in

(PMID:21873635)

NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732

SYT10

synaptotagmin 10

involved_in

(PMID:21873635)

NCBI chr27:15,593,709...15,657,184
Ensembl chr27:15,593,649...15,687,920

SYT11

synaptotagmin 11

involved_in

(PMID:21873635)

NCBI chr 7:41,910,102...41,929,020
Ensembl chr 7:41,912,920...41,929,617

SYT12

synaptotagmin 12

involved_in

(PMID:21873635)

NCBI chr18:50,334,779...50,358,113
Ensembl chr18:50,336,042...50,351,333

SYT13

synaptotagmin 13

involved_in

(PMID:21873635)

NCBI chr18:44,061,220...44,105,742
Ensembl chr18:44,061,271...44,102,382

SYT3

synaptotagmin 3

involved_in

(PMID:21873635)

NCBI chr 1:106,145,524...106,160,942
Ensembl chr 1:106,145,356...106,160,942

synaptotagmin 4

involved_in

(PMID:21873635)

NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714

SYT5

synaptotagmin 5

involved_in

(PMID:21873635)

NCBI chr 1:102,456,767...102,463,750
Ensembl chr 1:102,456,782...102,463,749

SYT6

synaptotagmin 6

involved_in

(PMID:21873635)

NCBI chr17:51,859,564...51,923,044
Ensembl chr17:51,864,774...51,924,676

synaptotagmin 7

involved_in

(PMID:21873635)

NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367

SYT8

synaptotagmin 8

involved_in

(PMID:21873635)

NCBI chr18:46,069,380...46,075,477
Ensembl chr18:46,072,495...46,075,480

SYT9

synaptotagmin 9

involved_in

(PMID:21873635)

NCBI chr21:30,985,059...31,123,986
Ensembl chr21:30,986,521...31,162,414

TSPAN18

tetraspanin 18

acts_upstream_of_or_within
involved_in

(MGI:6459621|PMID:30573509)

PMID:30573509

GO_REF:0000107 MGI:6459621

NCBI chr18:44,386,676...44,539,859
Ensembl chr18:44,388,761...44,445,847

vesicle associated membrane protein 2

acts_upstream_of_or_within

(MGI:2384381|PMID:12145198)
(MGI:3589987|PMID:15920476)

PMID:12145198 PMID:15920476

MGI:2384381 MGI:3589987

NCBI chr 5:32,975,372...32,977,967

VAMP3

vesicle associated membrane protein 3

acts_upstream_of_or_within
involved_in

(MGI:3589987|PMID:15920476)

PMID:15920476

GO_REF:0000107 MGI:3589987

NCBI chr 5:61,430,711...61,440,626
Ensembl chr 5:61,430,740...61,439,063

vesicle associated membrane protein 7

involved_in

PMID:14993220

NCBI chr X:123,717,524...123,783,781
Ensembl chr X:123,717,446...123,783,014

catecholamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CADPS

calcium dependent secretion activator

acts_upstream_of_or_within
involved_in

(MGI:3583730|PMID:15820695)

PMID:15820695

GO_REF:0000107 MGI:3583730

NCBI chr20:28,221,150...28,680,844
Ensembl chr20:28,221,843...28,680,131

MECP2

methyl-CpG binding protein 2

acts_upstream_of

(MGI:3686581|PMID:17050729)

PMID:17050729

MGI:3686581

NCBI chr X:121,866,721...121,876,088
Ensembl chr X:121,873,218...121,932,994

MECP2

methyl-CpG binding protein 2

involved_in

GO_REF:0000107

PINK1

PTEN induced kinase 1

acts_upstream_of
involved_in

(MGI:3715376|PMID:17563363)

PMID:17563363

GO_REF:0000107 MGI:3715376

NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123

constitutive secretory pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB11B

RAB11B, member RAS oncogene family

involved_in

(PMID:21873635)

NCBI chr20:52,955,949...52,966,279
Ensembl chr20:52,956,529...52,965,383

TMEM167A

transmembrane protein 167A

involved_in

GO_REF:0000107

NCBI chr 3:24,547,518...24,569,624
Ensembl chr 3:24,547,630...24,566,947

TMEM167B

transmembrane protein 167B

involved_in

(PMID:19942856)

PMID:19942856

NCBI chr 6:42,696,240...42,702,135
Ensembl chr 6:42,698,543...42,701,986

TRAPPC11

trafficking protein particle complex subunit 11

involved_in

GO_REF:0000107

NCBI chr16:46,687,514...46,735,909
Ensembl chr16:46,687,516...46,733,001

cortical granule exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYH9

myosin heavy chain 9

involved_in

UniProt
Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr10:28,063,626...28,122,953
Ensembl chr10:28,063,624...28,122,953

NLRP5

NLR family pyrin domain containing 5

involved_in

(MGI:6323780|PMID:31118423)

PMID:31118423

MGI:6323780

NCBI chr 1:101,813,449...101,842,643
Ensembl chr 1:101,813,449...101,842,633

corticosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KCNQ1

potassium voltage-gated channel subfamily Q member 1

involved_in

GO_REF:0000107

NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043

SELENOM

selenoprotein M

acts_upstream_of_or_within
involved_in

(MGI:5527224|PMID:23880772)

PMID:23880772

GO_REF:0000107 MGI:5527224

NCBI chr26:24,108,342...24,111,005
Ensembl chr26:24,108,344...24,111,005

corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AQP1

aquaporin 1

acts_upstream_of_or_within
involved_in

(MGI:3805139|PMID:18511498)

PMID:18511498

GO_REF:0000107 MGI:3805139

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

CRHR1

corticotropin releasing hormone receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402

cortisol secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

POMC

proopiomelanocortin

involved_in

(PMID:15201064)

PMID:15201064

NCBI chr17:19,431,396...19,438,247
Ensembl chr17:19,431,585...19,434,440

cytotoxic T cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB27A, member RAS oncogene family

involved_in
acts_upstream_of_or_within

(MGI:3653524|PMID:11266473)

PMID:11266473

GO_REF:0000107 MGI:3653524

NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521

STX11

syntaxin 11

acts_upstream_of_or_within

(MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531)

PMID:23042080 PMID:23190531

MGI:5460953 MGI:5471188

NCBI chr 1:35,600,440...35,645,421
Ensembl chr 1:35,601,133...35,644,819

dense core granule docking

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

UNC13A

unc-13 homolog A

NOT|involved_in

(MGI:5819330|PMID:26575293)

SynGO-UCL

PMID:26575293

MGI:5819330

NCBI chr20:45,179,275...45,237,544
Ensembl chr20:45,188,750...45,238,115

unc-13 homolog B

NOT|involved_in

(MGI:5819330|PMID:26575293)

SynGO-UCL

PMID:26575293

MGI:5819330

NCBI chr11:51,707,968...51,941,148
Ensembl chr11:51,708,302...51,940,955

dense core granule exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CADPS

calcium dependent secretion activator

involved_in

GO_REF:0000002

NCBI chr20:28,221,150...28,680,844
Ensembl chr20:28,221,843...28,680,131

CADPS2

calcium dependent secretion activator 2

involved_in

GO_REF:0000002

NCBI chr14:60,109,253...60,465,982
Ensembl chr14:60,107,538...60,556,817

dense core granule priming

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

UNC13A

unc-13 homolog A

involved_in

(PMID:21873635)

NCBI chr20:45,179,275...45,237,544
Ensembl chr20:45,188,750...45,238,115

unc-13 homolog B

involved_in

(PMID:21873635)

NCBI chr11:51,707,968...51,941,148
Ensembl chr11:51,708,302...51,940,955

UNC13C

unc-13 homolog C

involved_in

(PMID:21873635)

NCBI chr30:19,519,177...20,096,633
Ensembl chr30:19,518,232...20,095,094

UNC13D

unc-13 homolog D

involved_in

PMID:26575293

NCBI chr 9:4,753,300...4,766,751
Ensembl chr 9:4,753,166...4,766,756

dopamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHRNB2

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of

(MGI:1194464|PMID:9428762)

PMID:9428762

MGI:1194464

NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722

KPNA4

karyopherin subunit alpha 4

involved_in
acts_upstream_of_positive_effect

(PMID:32273471)

Ensembl
UniProt

PMID:32273471

GO_REF:0000107

NCBI chr34:26,549,071...26,614,537
Ensembl chr34:26,555,507...26,614,542

PINK1

PTEN induced kinase 1

acts_upstream_of
involved_in

(MGI:3715376|PMID:17563363)

PMID:17563363

GO_REF:0000107 MGI:3715376

NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123

TGM2

transglutaminase 2

involved_in
acts_upstream_of_positive_effect

(PMID:32273471)

Ensembl
UniProt

PMID:32273471

GO_REF:0000107

NCBI chr24:26,631,339...26,662,723
Ensembl chr24:26,628,009...26,663,840

eosinophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCL3

chemokine (C-C motif) ligand 3

involved_in

GO_REF:0000024

NCBI chr 9:37,693,711...37,695,137
Ensembl chr 9:37,686,480...37,695,573

FCER1A

Fc epsilon receptor Ia

involved_in

(PMID:8114916)

PMID:8114916

NCBI chr38:22,683,478...22,688,842
Ensembl chr38:22,683,477...22,690,763

vesicle associated membrane protein 2

involved_in

GO_REF:0000107

NCBI chr 5:32,975,372...32,977,967

vesicle associated membrane protein 7

involved_in

PMID:14993220
(PMID:16677249)

PMID:14993220 PMID:16677249

RGD:8553828

NCBI chr X:123,717,524...123,783,781
Ensembl chr X:123,717,446...123,783,014

VAMP8

vesicle associated membrane protein 8

NOT|involved_in

(PMID:16677249)

PMID:16677249

NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739

epinephrine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LY6E

lymphocyte antigen 6 family member E

acts_upstream_of_or_within

(MGI:2157257|PMID:11784869)

PMID:11784869

MGI:2157257

NCBI chr13:36,926,776...36,930,265
Ensembl chr13:36,925,980...36,974,979

evoked neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692

exocytic insertion of neurotransmitter receptor to postsynaptic membrane

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SACM1L

SAC1 like phosphatidylinositide phosphatase

involved_in

(MGI:6705856|PMID:32931550)

PMID:32931550

MGI:6705856

NCBI chr20:42,731,674...42,791,455
Ensembl chr20:42,720,249...42,791,402

SNAP23

synaptosome associated protein 23

involved_in

PMID:26839408

NCBI chr30:9,453,931...9,493,506
Ensembl chr30:9,456,084...9,492,329

SNAP25

synaptosome associated protein 25

involved_in

GO_REF:0000107

NCBI chr24:12,003,005...12,081,385
Ensembl chr24:12,004,117...12,081,329

SNAP47

synaptosome associated protein 47

involved_in

(MGI:5494785|PMID:23395379)

PMID:23395379

MGI:5494785

NCBI chr14:1,058,891...1,104,568
Ensembl chr14:1,056,802...1,104,574

STX1B

syntaxin 1B

involved_in

(PMID:21873635)

NCBI chr 6:17,209,972...17,219,903
Ensembl chr 6:17,210,433...17,241,363

STX3

syntaxin 3

involved_in

(PMID:21873635)

NCBI chr21:50,298,040...50,322,773
Ensembl chr21:50,298,158...50,318,663

STX4

syntaxin 4

involved_in

PMID:20434989

NCBI chr 6:17,184,044...17,189,481
Ensembl chr 6:17,184,399...17,189,370

vesicle associated membrane protein 2

involved_in

PMID:26839408
(MGI:5494785|PMID:23395379)

PMID:23395379 PMID:26839408

MGI:5494785 RGD:12050145

NCBI chr 5:32,975,372...32,977,967

exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARFGEF2

ADP ribosylation factor guanine nucleotide exchange factor 2

NCBI chr24:35,648,650...35,744,815
Ensembl chr24:35,648,431...35,744,584

BAIAP3

BAI1 associated protein 3

involved_in

GO_REF:0000043

NCBI chr 6:39,421,019...39,434,539
Ensembl chr 6:39,427,520...39,435,596

calcium voltage-gated channel subunit alpha1 C

NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429

CADPS

calcium dependent secretion activator

NOT|acts_upstream_of_or_within
involved_in

PMID:15820695 PMID:21873635

(MGI:3583730|PMID:15820695)
(PMID:21873635)

MGI
UniProt
GO_Central

GO_REF:0000043 MGI:3583730

NCBI chr20:28,221,150...28,680,844
Ensembl chr20:28,221,843...28,680,131

CADPS2

calcium dependent secretion activator 2

involved_in

(PMID:21873635)

GO_Central
UniProt

GO_REF:0000043

NCBI chr14:60,109,253...60,465,982
Ensembl chr14:60,107,538...60,556,817

CCL3

chemokine (C-C motif) ligand 3

involved_in

GO_REF:0000024

NCBI chr 9:37,693,711...37,695,137
Ensembl chr 9:37,686,480...37,695,573

CCL5

C-C motif chemokine ligand 5

involved_in

(PMID:10734056)

PMID:10734056

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

CCL8

C-C motif chemokine ligand 8

involved_in

GO_REF:0000107

NCBI chr 9:38,949,184...38,950,702
Ensembl chr 9:38,948,184...38,950,803

CCR1

chemokine (C-C motif) receptor 1

involved_in

GO_REF:0000107

NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958

CDK16

cyclin dependent kinase 16

involved_in

(PMID:21873635)

NCBI chr X:40,810,107...40,822,130
Ensembl chr X:40,810,500...40,842,700

CDK5

cyclin dependent kinase 5

NCBI chr16:15,105,177...15,113,085
Ensembl chr16:15,101,230...15,109,269

CKM

creatine kinase, M-type

involved_in

GO_REF:0000002

NCBI chr 1:110,210,158...110,218,937
Ensembl chr 1:110,210,152...110,343,383

CLEC19A

C-type lectin domain containing 19A

involved_in

GO_REF:0000002

NCBI chr 6:26,082,725...26,103,129

CPLANE2

ciliogenesis and planar polarity effector complex subunit 2

involved_in

GO_REF:0000043

NCBI chr 2:81,468,095...81,473,646
Ensembl chr 2:81,469,802...81,473,947

CPLX1

complexin 1

involved_in

GO_REF:0000043

NCBI chr 3:91,635,953...91,658,084
Ensembl chr 3:91,638,515...91,656,737

CPLX2

complexin 2

involved_in

GO_REF:0000043

NCBI chr 4:37,203,003...37,275,938
Ensembl chr 4:37,206,082...37,275,954

involved_in

GO_REF:0000043

complexin 3

involved_in

GO_REF:0000043

NCBI chr30:37,888,770...37,893,168
Ensembl chr30:37,888,076...37,893,182

CPLX4

complexin 4

involved_in

GO_REF:0000043

NCBI chr 1:16,900,078...16,922,914
Ensembl chr 1:16,900,826...16,922,140

DOC2B

double C2 domain beta

NCBI chr 9:45,450,270...45,488,638
Ensembl chr 9:45,450,302...45,485,247

EXOC1

exocyst complex component 1

involved_in

GO_Central
InterPro
UniProt

(PMID:21873635)

GO_REF:0000002 GO_REF:0000043

NCBI chr13:48,109,773...48,177,070
Ensembl chr13:48,109,810...48,176,177

EXOC1L

exocyst complex component 1 like

involved_in

(PMID:21873635)

NCBI chr13:48,073,183...48,090,042
Ensembl chr13:48,073,596...48,089,911

EXOC2

exocyst complex component 2

involved_in

GO_Central
UniProt
UniProt

(PMID:21873635)

GO_REF:0000043

NCBI chr35:859,158...1,084,228
Ensembl chr35:859,837...1,084,228

EXOC3

exocyst complex component 3

involved_in

(PMID:21873635)

GO_REF:0000002

NCBI chr34:11,790,927...11,811,566
Ensembl chr34:11,791,926...11,811,561

EXOC3L1

exocyst complex component 3 like 1

involved_in

GO_Central
Ensembl
InterPro

(PMID:21873635)

GO_REF:0000002 GO_REF:0000107

NCBI chr 5:82,176,552...82,182,423
Ensembl chr 5:82,176,960...82,190,214

EXOC3L2

exocyst complex component 3 like 2

involved_in

(PMID:21873635)

GO_REF:0000002

NCBI chr 1:110,265,054...110,277,895
Ensembl chr 1:110,265,043...110,277,519

EXOC3L4

exocyst complex component 3 like 4

involved_in

GO_REF:0000002

NCBI chr 8:70,943,515...70,956,211
Ensembl chr 8:70,946,994...70,955,867

EXOC4

exocyst complex component 4

involved_in

(PMID:21873635)

GO_Central
UniProt

GO_REF:0000043 GO_REF:0000104

NCBI chr14:3,334,286...4,077,478
Ensembl chr14:3,334,220...4,077,411

EXOC5

exocyst complex component 5

involved_in

(PMID:21873635)

GO_REF:0000002

NCBI chr 8:32,789,311...32,848,045
Ensembl chr 8:32,778,715...32,848,050

EXOC6

exocyst complex component 6

involved_in

GO_Central
UniProt
GO_Central

(PMID:21873635)

GO_REF:0000043

NCBI chr28:7,190,918...7,414,367
Ensembl chr28:7,207,194...7,414,362

EXOC6B

exocyst complex component 6B

involved_in

(PMID:21873635)

GO_Central
UniProt

GO_REF:0000043

NCBI chr17:49,986,330...50,607,658
Ensembl chr17:49,986,390...50,604,451

EXOC7

exocyst complex component 7

involved_in

GO_Central
InterPro
UniProt
UniProt

(PMID:21873635)

GO_REF:0000002 GO_REF:0000043

NCBI chr 9:4,538,017...4,554,341
Ensembl chr 9:4,537,944...4,554,328

EXOC8

exocyst complex component 8

acts_upstream_of_or_within
involved_in

(PMID:14525976)

MGI
Ensembl
UniProt
InterPro
Ensembl

PMID:14525976

GO_REF:0000002 GO_REF:0000043 GO_REF:0000107

NCBI chr 4:8,133,526...8,138,185
Ensembl chr 4:8,133,670...8,135,853

EXOC8

exocyst complex component 8

involved_in

InterPro
Ensembl
UniProt

GO_REF:0000002 GO_REF:0000043 GO_REF:0000107

glucagon receptor

NCBI chr 9:455,744...463,070
Ensembl chr 9:344,438...459,925

HRH2

histamine receptor H2

involved_in

GO_REF:0000043

NCBI chr 4:37,333,843...37,407,146
Ensembl chr 4:37,275,852...37,386,072

KCNB1

potassium voltage-gated channel subfamily B member 1

involved_in

GO_REF:0000043

NCBI chr24:36,016,800...36,118,873
Ensembl chr24:36,025,472...36,117,934

LIN7A

lin-7 homolog A, crumbs cell polarity complex component

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr15:23,101,524...23,186,343
Ensembl chr15:23,111,944...23,187,354

LIN7B

lin-7 homolog B, crumbs cell polarity complex component

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 1:107,332,623...107,336,099
Ensembl chr 1:107,332,623...107,336,302
Ensembl chr 1:107,332,623...107,336,302

LIN7C

lin-7 homolog C, crumbs cell polarity complex component

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr21:48,061,446...48,071,458
Ensembl chr21:48,064,929...48,071,429

LLGL1

LLGL scribble cell polarity complex component 1

involved_in

GO_REF:0000043

NCBI chr 5:41,314,807...41,332,687
Ensembl chr 5:41,315,152...41,332,896

LLGL2

LLGL scribble cell polarity complex component 2

involved_in

GO_REF:0000043

NCBI chr 9:4,975,309...5,008,383
Ensembl chr 9:4,975,660...4,996,775

LOC119864910

protein lin-7 homolog C

involved_in

GO_REF:0000043 GO_REF:0000104

MIA3

MIA SH3 domain ER export factor 3

involved_in

GO_REF:0000107

NCBI chr38:16,880,411...16,936,368
Ensembl chr38:16,879,740...16,935,844

MICAL3

microtubule associated monooxygenase, calponin and LIM domain containing 3

involved_in

GO_REF:0000043

NCBI chr27:45,399,370...45,618,306
Ensembl chr27:45,403,392...45,550,055

MYH10

myosin heavy chain 10

acts_upstream_of_or_within

(MGI:3042318|PMID:14617807)

PMID:14617807

MGI:3042318

NCBI chr 5:33,239,800...33,360,459
Ensembl chr 5:33,241,266...33,360,934

MYO1G

myosin IG

acts_upstream_of_or_within
involved_in

(MGI:5566942|PMID:24310084)

PMID:24310084

GO_REF:0000107 MGI:5566942

MYO5A

myosin VA

acts_upstream_of_or_within

(MGI:3589494|PMID:15788565)

PMID:15788565

MGI:3589494

NCBI chr30:17,990,521...18,122,160
Ensembl chr30:17,888,419...18,213,061

NLRP5

NLR family pyrin domain containing 5

involved_in

(MGI:5553206|PMID:24374158)

PMID:24374158

MGI:5553206

NCBI chr 1:101,813,449...101,842,643
Ensembl chr 1:101,813,449...101,842,633

PRSS12

serine protease 12

involved_in

GO_REF:0000107

NCBI chr32:37,509,662...37,586,933
Ensembl chr32:37,509,124...37,587,155

RAB11A

RAB11A, member RAS oncogene family

involved_in

(PMID:21873635)

GO_Central
GO_Central

NCBI chr30:30,200,831...30,218,412
Ensembl chr30:30,200,831...30,218,411

RAB11B

RAB11B, member RAS oncogene family

involved_in

(PMID:21873635)

NCBI chr20:52,955,949...52,966,279
Ensembl chr20:52,956,529...52,965,383

RAB25

RAB25, member RAS oncogene family

involved_in

(PMID:21873635)

GO_Central
GO_Central

NCBI chr 7:41,752,975...41,758,954
Ensembl chr 7:41,752,975...41,758,906

RAB27A, member RAS oncogene family

involved_in

UniProt
Ensembl

GO_REF:0000043 GO_REF:0000107

NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692

RAB3IL1

RAB3A interacting protein like 1

involved_in

(PMID:21873635)

NCBI chr18:54,483,669...54,528,199
Ensembl chr18:54,484,177...54,547,523

RAB3IP

RAB3A interacting protein

involved_in

(PMID:21873635)

NCBI chr10:11,673,749...11,714,282
Ensembl chr10:11,673,777...11,714,281

RIMS1

regulating synaptic membrane exocytosis 1

involved_in

GO_REF:0000002

NCBI chr12:34,473,974...34,661,893
Ensembl chr12:34,474,033...34,659,410

regulating synaptic membrane exocytosis 2

involved_in

GO_REF:0000002

NCBI chr13:4,928,518...5,499,258
Ensembl chr13:4,927,121...5,496,629

RIMS3

regulating synaptic membrane exocytosis 3

involved_in

GO_REF:0000002

NCBI chr15:2,353,876...2,391,742
Ensembl chr15:2,353,693...2,404,431

RIMS4

regulating synaptic membrane exocytosis 4

involved_in

GO_REF:0000002

NCBI chr24:32,199,068...32,256,474
Ensembl chr24:32,203,410...32,256,480

SCAMP1

secretory carrier membrane protein 1

involved_in
acts_upstream_of_or_within

(MGI:1347371|PMID:10551807)

PMID:10551807

GO_REF:0000107 MGI:1347371

NCBI chr 3:28,296,229...28,417,398
Ensembl chr 3:28,274,205...28,417,496

SNAP23

synaptosome associated protein 23

involved_in
acts_upstream_of_or_within

PMID:18505797 PMID:21873635

(PMID:21873635)
(MGI:3810032|PMID:18505797)

GO_Central
MGI

MGI:3810032

NCBI chr30:9,453,931...9,493,506
Ensembl chr30:9,456,084...9,492,329

SNAP25

synaptosome associated protein 25

involved_in

(PMID:21873635)

NCBI chr24:12,003,005...12,081,385
Ensembl chr24:12,004,117...12,081,329

SNAP29

synaptosome associated protein 29

involved_in

(PMID:21873635)

NCBI chr26:30,606,195...30,630,441
Ensembl chr26:30,609,158...30,630,262

SNAP47

synaptosome associated protein 47

involved_in

(PMID:21873635)

NCBI chr14:1,058,891...1,104,568
Ensembl chr14:1,056,802...1,104,574

STX11

syntaxin 11

involved_in

(PMID:21873635)

NCBI chr 1:35,600,440...35,645,421
Ensembl chr 1:35,601,133...35,644,819

STX17

syntaxin 17

involved_in

(PMID:21873635)

NCBI chr11:56,885,874...56,951,714
Ensembl chr11:56,885,174...56,945,767

STX19

syntaxin 19

involved_in

(PMID:21873635)

NCBI chr33:1,726,019...1,736,949
Ensembl chr33:1,726,695...1,727,579

syntaxin 1A

involved_in

(PMID:21873635)

NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833

STX1B

syntaxin 1B

involved_in

(PMID:21873635)

NCBI chr 6:17,209,972...17,219,903
Ensembl chr 6:17,210,433...17,241,363

STX2

syntaxin 2

involved_in

(PMID:21873635)

NCBI chr26:1,459,110...1,494,801
Ensembl chr26:1,454,189...1,494,823

STX3

syntaxin 3

acts_upstream_of_or_within
involved_in

PMID:18505797 PMID:21873635

(MGI:3810032|PMID:18505797)
(PMID:21873635)

MGI
InterPro
GO_Central

GO_REF:0000002 MGI:3810032

NCBI chr21:50,298,040...50,322,773
Ensembl chr21:50,298,158...50,318,663

STX4

syntaxin 4

involved_in

(PMID:21873635)

NCBI chr 6:17,184,044...17,189,481
Ensembl chr 6:17,184,399...17,189,370

STXBP1

syntaxin binding protein 1

acts_upstream_of_or_within
involved_in

(MGI:3621672|PMID:11545717)

PMID:11545717

GO_REF:0000107 MGI:3621672

NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680

STXBP2

syntaxin binding protein 2

acts_upstream_of_or_within
involved_in

(MGI:3810032|PMID:18505797)

PMID:18505797

GO_REF:0000107 MGI:3810032

NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517

STXBP3

syntaxin binding protein 3

acts_upstream_of_or_within
involved_in

(MGI:4352814|PMID:19188424)

PMID:19188424

GO_REF:0000107 MGI:4352814

NCBI chr 6:42,947,639...42,998,297
Ensembl chr 6:42,948,236...43,053,027

STXBP5

syntaxin binding protein 5

involved_in
acts_upstream_of_or_within

(MGI:3050225|PMID:12832401)

UniProt
Ensembl
UniProt
MGI

PMID:12832401

GO_REF:0000043 GO_REF:0000107 MGI:3050225

NCBI chr 1:38,271,238...38,439,088
Ensembl chr 1:38,271,154...38,434,042

STXBP5L

syntaxin binding protein 5L

involved_in

GO_REF:0000043

NCBI chr33:24,320,625...24,702,782
Ensembl chr33:24,320,650...24,697,153

STXBP6

syntaxin binding protein 6

involved_in

(PMID:21873635)

NCBI chr 8:4,638,376...4,877,589
Ensembl chr 8:4,641,460...4,877,030

SYCN

syncollin

involved_in

GO_REF:0000002

NCBI chr 1:113,987,711...113,989,112
Ensembl chr 1:113,987,739...113,989,111

SYT16

synaptotagmin 16

involved_in

GO_REF:0000002

NCBI chr 8:36,820,031...36,945,267
Ensembl chr 8:36,839,334...36,934,378

SYT17

synaptotagmin 17

involved_in

GO_REF:0000002

NCBI chr 6:26,004,113...26,076,161

synaptotagmin 4

involved_in

GO_REF:0000002

NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714

synaptotagmin 7

involved_in

InterPro
Ensembl
GO_Central

GO_REF:0000002

NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367

SYTL1

synaptotagmin like 1

involved_in

IEA
IBA

(PMID:21873635)

GO_REF:0000002 GO_REF:0000107

NCBI chr 2:72,916,445...72,925,219
Ensembl chr 2:72,916,445...72,925,147

SYTL2

synaptotagmin like 2

involved_in

(PMID:21873635)

GO_Central
Ensembl
InterPro
MGI

GO_REF:0000002

NCBI chr21:13,639,054...13,756,332
Ensembl chr21:13,688,338...13,755,414

SYTL3

synaptotagmin like 3

involved_in
acts_upstream_of_or_within

IBA
IEA
ISO

(PMID:21873635)
(MGI:2657090|PMID:12590134)

PMID:12590134 PMID:21873635

GO_REF:0000002 GO_REF:0000107 MGI:2657090

NCBI chr 1:48,066,449...48,159,980
Ensembl chr 1:48,067,612...48,159,936

SYTL4

synaptotagmin like 4

acts_upstream_of_or_within
involved_in

MGI
Ensembl
InterPro
GO_Central

(MGI:2657090|PMID:12590134)
(PMID:21873635)

PMID:12590134 PMID:21873635

GO_REF:0000002 GO_REF:0000107 MGI:2657090

NCBI chr X:74,537,937...74,617,580
Ensembl chr X:74,539,183...74,565,753

SYTL5

synaptotagmin like 5

acts_upstream_of_or_within
involved_in

ISO
IBA

(MGI:2657090|PMID:12590134)
(PMID:21873635)

MGI
GO_Central

PMID:12590134 PMID:21873635

MGI:2657090

NCBI chr X:32,652,389...32,886,793
Ensembl chr X:32,651,968...32,879,525

TNFAIP2

TNF alpha induced protein 2

involved_in

(PMID:21873635)

GO_REF:0000002

NCBI chr 8:70,965,776...70,977,807
Ensembl chr 8:70,967,741...70,976,396

TRIM72

tripartite motif containing 72

involved_in

GO_REF:0000043

NCBI chr 6:17,031,175...17,053,399
Ensembl chr 6:17,031,913...17,039,556

UNC13A

unc-13 homolog A

involved_in

GO_REF:0000043

NCBI chr20:45,179,275...45,237,544
Ensembl chr20:45,188,750...45,238,115

unc-13 homolog B

involved_in

GO_REF:0000043

NCBI chr11:51,707,968...51,941,148
Ensembl chr11:51,708,302...51,940,955

UNC13C

unc-13 homolog C

involved_in

GO_REF:0000043

NCBI chr30:19,519,177...20,096,633
Ensembl chr30:19,518,232...20,095,094

UNC13D

unc-13 homolog D

involved_in

GO_REF:0000043

NCBI chr 9:4,753,300...4,766,751
Ensembl chr 9:4,753,166...4,766,756

USP11

ubiquitin specific peptidase 11

involved_in

(PMID:21873635)

NCBI chr X:40,826,648...40,842,700
Ensembl chr X:40,810,500...40,842,700

vesicle associated membrane protein 7

involved_in

(PMID:21873635)

NCBI chr X:123,717,524...123,783,781
Ensembl chr X:123,717,446...123,783,014

WASHC1

WASH complex subunit 1

involved_in

(PMID:24344185)

PMID:24344185

NCBI chr27:42,102,694...42,118,850
Ensembl chr27:42,099,886...42,116,339

WASHC3

WASH complex subunit 3

involved_in

(PMID:21873635)

NCBI chr15:40,871,793...40,916,534

exosomal secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COPS5

COP9 signalosome subunit 5

involved_in

GO_REF:0000107

NCBI chr29:16,562,234...16,579,082
Ensembl chr29:16,562,234...16,578,847

RAB11A

RAB11A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr30:30,200,831...30,218,412
Ensembl chr30:30,200,831...30,218,411

RAB27A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521

STEAP3

STEAP3 metalloreductase

acts_upstream_of_or_within

(MGI:4367682|PMID:18617898)

PMID:18617898

MGI:4367682

NCBI chr19:30,745,910...30,795,310
Ensembl chr19:30,747,921...30,795,338

TSG101

tumor susceptibility 101

involved_in

GO_REF:0000107

NCBI chr21:40,910,870...40,952,922
Ensembl chr21:40,910,874...40,952,808

extracellular matrix constituent secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCN2

cellular communication network factor 2

positive regulation

NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145

CREB3L1

cAMP responsive element binding protein 3 like 1

involved_in

(MGI:4438316|PMID:19767743)

PMID:19767743

MGI:4438316

NCBI chr18:43,138,779...43,173,535
Ensembl chr18:43,139,453...43,173,420

endoglin

NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064

TMEM38B

transmembrane protein 38B

acts_upstream_of_or_within
involved_in

(MGI:6141091|PMID:27188440)

PMID:27188440

GO_REF:0000107 MGI:6141091

NCBI chr11:61,511,756...61,561,987
Ensembl chr11:61,511,750...61,560,556

ZNF469

zinc finger protein 469

acts_upstream_of_or_within

(MGI:6765278|PMID:34368841)

PMID:34368841

MGI:6765278

NCBI chr 5:64,887,534...64,903,553

fast, calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 1

involved_in

GO_REF:0000107

NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732

follicle-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CGA

glycoprotein hormones, alpha polypeptide

acts_upstream_of_or_within

(MGI:1316794|PMID:12114718)

PMID:12114718

MGI:1316794

NCBI chr12:46,610,801...46,629,322
Ensembl chr12:46,610,973...46,636,640

TBX3

T-box transcription factor 3

involved_in

GO_REF:0000107

NCBI chr26:11,694,885...11,709,594
Ensembl chr26:11,696,565...11,708,918

gamma-aminobutyric acid secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NF1

neurofibromin 1

acts_upstream_of_or_within
involved_in

(MGI:5620820|PMID:25242307)

GO_REF:0000107 MGI:5620820

NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382

PAK1

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

(MGI:5620820|PMID:25242307)

MGI:5620820

NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416

ghrelin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FFAR4

free fatty acid receptor 4

involved_in

GO_REF:0000107

NCBI chr28:7,801,713...7,820,048
Ensembl chr28:7,801,713...7,820,048

growth hormone secretagogue receptor

NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312

glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL6

interleukin 6

involved_in

(MGI:3807360|PMID:18719127)

PMID:18719127

MGI:3807360

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

glutamate secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APBA1

amyloid beta precursor protein binding family A member 1

acts_upstream_of_or_within
involved_in

(MGI:3691953|PMID:17167098)

PMID:17167098

GO_REF:0000107 MGI:3691953

NCBI chr 1:87,787,039...87,980,204
Ensembl chr 1:87,786,836...87,980,194

BDNF

brain derived neurotrophic factor

acts_upstream_of_or_within

(MGI:3654775|PMID:16819522)

MGI:3654775

NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480

GIPC1

GIPC PDZ domain containing family member 1

acts_upstream_of_or_within
involved_in

(MGI:3654775|PMID:16819522)

GO_REF:0000107 MGI:3654775

NCBI chr20:48,144,076...48,155,069
Ensembl chr20:48,150,498...48,157,191

GJA1

gap junction protein alpha 1

involved_in

(MGI:6368305|PMID:26200696)

PMID:26200696

MGI:6368305

NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936

GRM2

glutamate metabotropic receptor 2

involved_in

PMID:15993439

NCBI chr20:37,915,178...37,926,276
Ensembl chr20:37,915,665...37,924,296

MYO6

myosin VI

acts_upstream_of_or_within

(MGI:3654775|PMID:16819522)

MGI:3654775

NCBI chr12:37,359,200...37,502,342
Ensembl chr12:37,413,570...37,500,724

NTRK2

neurotrophic receptor tyrosine kinase 2

acts_upstream_of_or_within
involved_in

(MGI:3654775|PMID:16819522)

GO_REF:0000107 MGI:3654775

NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032

P2RX7

purinergic receptor P2X 7

acts_upstream_of
involved_in

(MGI:3610634|PMID:15640761)
(MGI:3700006|PMID:17306762)

PMID:15640761 PMID:17306762

GO_REF:0000107 MGI:3610634 MGI:3700006

NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740

PTGER1

prostaglandin E receptor 1

involved_in

GO_REF:0000107

NCBI chr20:48,156,055...48,159,838
Ensembl chr20:48,157,973...48,159,921

TRPV1

transient receptor potential cation channel subfamily V member 1

NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926

glutamate secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NF1

neurofibromin 1

acts_upstream_of_or_within
involved_in

(MGI:5620820|PMID:25242307)

GO_REF:0000107 MGI:5620820

NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382

PAK1

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

(MGI:5620820|PMID:25242307)

MGI:5620820

NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416

glutamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC1A5

solute carrier family 1 member 5

NCBI chr 1:109,150,205...109,161,375
Ensembl chr 1:109,150,205...109,161,141

SLC38A3

solute carrier family 38 member 3

involved_in

GO_REF:0000107

NCBI chr20:39,108,387...39,122,526
Ensembl chr20:39,109,211...39,114,849

glycine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC6A9

solute carrier family 6 member 9

acts_upstream_of_or_within

(MGI:5523768|PMID:22988142)

PMID:22988142

MGI:5523768

NCBI chr15:16,235,342...16,267,161
Ensembl chr15:16,235,482...16,267,933

gonadotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NIBAN2

niban apoptosis regulator 2

involved_in

GO_REF:0000107

NCBI chr 9:55,802,010...55,853,960
Ensembl chr 9:55,802,014...55,852,540

growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

(MGI:51674|PMID:1385406)

PMID:1385406

MGI:51674

NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429

CDK16

cyclin dependent kinase 16

involved_in

(MGI:5447616|PMID:16461345)

PMID:16461345

MGI:5447616

NCBI chr X:40,810,107...40,822,130
Ensembl chr X:40,810,500...40,842,700

GHRH

growth hormone releasing hormone

involved_in
acts_upstream_of_or_within

(MGI:1098976|PMID:9348175)
(PMID:2857452)
(MGI:3607618|PMID:15985453)
(MGI:3039217|PMID:15070777)

PMID:2857452 PMID:9348175 PMID:15070777 PMID:15985453

GO_REF:0000107 MGI:1098976 MGI:3039217 MGI:3607618

NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712

GHRHR

growth hormone releasing hormone receptor

involved_in
acts_upstream_of

(MGI:56721|PMID:3008329)

PMID:3008329

GO_REF:0000107 MGI:56721

NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753

growth hormone secretagogue receptor

involved_in
acts_upstream_of_or_within

(MGI:3039217|PMID:15070777)

PMID:15070777

GO_REF:0000107 MGI:3039217

NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312

RAB1A

RAB1A, member RAS oncogene family

involved_in

IEA
ISS

Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr10:64,564,351...64,590,654
Ensembl chr10:64,564,298...64,590,705

histamine secretion by mast cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA3

adenosine A3 receptor

acts_upstream_of_or_within

(MGI:2664591|PMID:12817016)

PMID:12817016

MGI:2664591

NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666

BTK

Bruton tyrosine kinase

NCBI chr X:75,270,952...75,302,663
Ensembl chr X:75,270,979...75,302,562

LYN

LYN proto-oncogene, Src family tyrosine kinase

NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507

RAB44

RAB44, member RAS oncogene family

acts_upstream_of_or_within
involved_in

(MGI:6693988|PMID:32238914)

PMID:32238914

GO_REF:0000107 MGI:6693988

NCBI chr12:5,769,056...5,804,963
Ensembl chr12:5,770,882...5,804,949

SLC18A2

solute carrier family 18 member A2

involved_in

GO_REF:0000107

NCBI chr28:27,731,709...27,809,341
Ensembl chr28:27,731,004...27,767,993

SNAP23

synaptosome associated protein 23

involved_in

GO_REF:0000107

NCBI chr30:9,453,931...9,493,506
Ensembl chr30:9,456,084...9,492,329

YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

NCBI chr13:2,729,404...2,764,422

histamine secretion mediated by IgE immunoglobulin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB44

RAB44, member RAS oncogene family

acts_upstream_of_or_within
involved_in

(MGI:6693988|PMID:32238914)

PMID:32238914

GO_REF:0000107 MGI:6693988

NCBI chr12:5,769,056...5,804,963
Ensembl chr12:5,770,882...5,804,949

hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CREB1

cAMP responsive element binding protein 1

involved_in
acts_upstream_of

(MGI:3611103|PMID:16141355)

PMID:15619630 PMID:21873635

PMID:16141355

GO_REF:0000107 MGI:3611103

NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556

FFAR4

free fatty acid receptor 4

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

(MGI:3526005|PMID:15619630)
(PMID:21873635)

Ensembl
MGI
GO_Central

GO_REF:0000107 MGI:3526005

NCBI chr28:7,801,713...7,820,048
Ensembl chr28:7,801,713...7,820,048

GHRH

growth hormone releasing hormone

involved_in
acts_upstream_of

(MGI:3607618|PMID:15985453), (MGI:3695097|PMID:16246898)

PMID:15985453 PMID:16246898

GO_REF:0000107 MGI:3607618 MGI:3695097

NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712

GHRHR

growth hormone releasing hormone receptor

involved_in
acts_upstream_of

(MGI:52244|PMID:7679139)

PMID:7679139

GO_REF:0000107 MGI:52244

NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753

GLP1R

glucagon like peptide 1 receptor

acts_upstream_of_or_within_positive_effect
involved_in

PMID:8828468 PMID:23542788

(MGI:5496464|PMID:23542788)
PMID:8828468

MGI
UniProt

MGI:5496464 RGD:8554483

NCBI chr12:7,999,963...8,030,335
Ensembl chr12:7,999,997...8,025,048

LTBP4

latent transforming growth factor beta binding protein 4

involved_in
acts_upstream_of_or_within

(MGI:2386340|PMID:12208849)

PMID:12208849

GO_REF:0000107 MGI:2386340

NCBI chr 1:113,124,109...113,152,283
Ensembl chr 1:113,124,109...113,150,442

RAPGEF4

Rap guanine nucleotide exchange factor 4

involved_in
acts_upstream_of_or_within_positive_effect

(MGI:5496464|PMID:23542788)

PMID:23542788

GO_REF:0000107 MGI:5496464

NCBI chr36:17,087,488...17,323,504
Ensembl chr36:17,087,488...17,323,220

syntaxin 1A

involved_in

(MGI:5916295|PMID:28596237)

PMID:28596237

MGI:5916295

NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833

vesicle associated membrane protein 2

involved_in

(MGI:6294198|PMID:24356748)

PMID:24356748

MGI:6294198

NCBI chr 5:32,975,372...32,977,967

induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1D

calcium voltage-gated channel subunit alpha1 D

involved_in

GOC

GO_REF:0000108

NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686

insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR1C

activin A receptor type 1C

acts_upstream_of
involved_in

(MGI:3796011|PMID:18480258)

PMID:18480258

GO_REF:0000107 MGI:3796011

NCBI chr36:3,534,231...3,583,310
Ensembl chr36:3,541,248...3,613,384

ACVR2B

activin A receptor type 2B

acts_upstream_of_or_within

(MGI:3758991|PMID:17849440)

PMID:17849440

MGI:3758991

NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894

ADCYAP1

adenylate cyclase activating polypeptide 1

involved_in

GO_REF:0000002

NCBI chr 7:67,682,421...67,691,035

ANXA1

annexin A1

involved_in

PMID:12459455 PMID:21873635

(PMID:21873635)

GO_Central
RGD

RGD:628365

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

ANXA7

annexin A7

acts_upstream_of

(MGI:4459350|PMID:20440069)

PMID:20440069

MGI:4459350

NCBI chr 4:23,933,959...23,961,968
Ensembl chr 4:23,934,234...23,961,880

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

(MGI:2670808|PMID:12881419)

PMID:12881419

MGI:2670808

NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429

CCKAR

cholecystokinin A receptor

NCBI chr 3:84,010,700...84,019,066
Ensembl chr 3:84,010,205...84,021,293

CPLX1

complexin 1

involved_in

(MGI:3688343|PMID:15126625)

PMID:15126625

MGI:3688343

NCBI chr 3:91,635,953...91,658,084
Ensembl chr 3:91,638,515...91,656,737

CPLX3

complexin 3

involved_in

GO_REF:0000107

NCBI chr30:37,888,770...37,893,168
Ensembl chr30:37,888,076...37,893,182

CYB5R4

cytochrome b5 reductase 4

acts_upstream_of_or_within
involved_in

(MGI:3047191|PMID:15247412)

PMID:15247412

GO_REF:0000107 MGI:3047191

NCBI chr12:44,170,571...44,247,494
Ensembl chr12:44,141,582...44,247,493

DGAT1

diacylglycerol O-acyltransferase 1

NCBI chr13:37,745,395...37,761,337
Ensembl chr13:37,741,706...37,756,916

FAM3B

FAM3 metabolism regulating signaling molecule B

involved_in

GO_Central
Ensembl
InterPro

(PMID:21873635)

GO_REF:0000002 GO_REF:0000107

NCBI chr31:35,805,981...35,844,258
Ensembl chr31:35,806,217...35,844,263

FFAR1

free fatty acid receptor 1

acts_upstream_of_or_within
involved_in

(MGI:3713161|PMID:17395749)

PMID:17395749

GO_REF:0000107 MGI:3713161

NCBI chr 1:117,257,005...117,258,799

FKBP1B

FKBP prolyl isomerase 1B

involved_in
acts_upstream_of_or_within

(MGI:3795616|PMID:18466757)

Ensembl
MGI
Ensembl

PMID:18466757

GO_REF:0000107 MGI:3795616

NCBI chr17:18,534,295...18,544,973
Ensembl chr17:18,534,741...18,544,943

GLP1R

glucagon like peptide 1 receptor

involved_in

PMID:10362617

NCBI chr12:7,999,963...8,030,335
Ensembl chr12:7,999,997...8,025,048

GPR119

G protein-coupled receptor 119

acts_upstream_of_or_within
involved_in

(MGI:3522385|PMID:15607732)

PMID:15607732

GO_REF:0000107 MGI:3522385

NCBI chr X:101,518,313...101,520,677
Ensembl chr X:101,518,977...101,519,984

GPR39

G protein-coupled receptor 39

acts_upstream_of

(MGI:4355293|PMID:19213841)

PMID:19213841

MGI:4355293

NCBI chr19:35,385,835...35,585,953
Ensembl chr19:35,385,829...35,586,507

GPR68

G protein-coupled receptor 68

acts_upstream_of
involved_in

(MGI:5444590|PMID:22733973)

PMID:22733973

GO_REF:0000107 MGI:5444590

NCBI chr 8:62,090,050...62,108,922
Ensembl chr 8:62,092,135...62,093,217

HNF1A

HNF1 homeobox A

involved_in
acts_upstream_of_or_within

PMID:9566924 PMID:9593777 PMID:9733737 PMID:15142986

(MGI:1202489|PMID:9566924), (MGI:1298140|PMID:9733737)
(MGI:1266996|PMID:9593777), (MGI:3047439|PMID:15142986)

Ensembl
Ensembl
InterPro
MGI

GO_REF:0000002 GO_REF:0000107 MGI:1202489 MGI:1266996 MGI:1298140 MGI:3047439

NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790

HNF1B

HNF1 homeobox B

involved_in
acts_upstream_of_or_within

(MGI:3047439|PMID:15142986)

Ensembl
InterPro
Ensembl
InterPro
MGI

PMID:15142986

GO_REF:0000002 GO_REF:0000107 MGI:3047439

NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993

HTT

huntingtin

acts_upstream_of_or_within

(MGI:1333401|PMID:10078572)

PMID:10078572

MGI:1333401

NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290

IL1RN

interleukin 1 receptor antagonist

acts_upstream_of_or_within
involved_in

(MGI:2675567|PMID:12975454)

PMID:12975454

GO_REF:0000107 MGI:2675567

NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329

ILDR2

immunoglobulin like domain containing receptor 2

acts_upstream_of_or_within
involved_in

(MGI:3804573|PMID:18654634)

PMID:18654634

GO_REF:0000107 MGI:3804573

NCBI chr 7:31,409,015...31,469,741
Ensembl chr 7:31,408,814...31,464,943

IRS1

insulin receptor substrate 1

NOT|acts_upstream_of_or_within

(MGI:86285|PMID:9062343)

PMID:9062343

MGI:86285

NCBI chr25:39,624,554...39,687,991

LEP

leptin

acts_upstream_of_or_within
involved_in

(MGI:3770192|PMID:16141392)

PMID:16141392

GO_REF:0000107 MGI:3770192

NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395

LOC119869900

small nucleolar RNA Z195/SNORD33/SNORD32 family

acts_upstream_of_or_within

(MGI:5816855|PMID:27820699)

small nucleolar RNA SNORD34

acts_upstream_of_or_within

(MGI:5816855|PMID:27820699)

small nucleolar RNA SNORD35

acts_upstream_of_or_within

(MGI:5816855|PMID:27820699)

peptidyl-prolyl cis-trans isomerase FKBP1B

involved_in

GO_REF:0000107

MAFA

MAF bZIP transcription factor A

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr13:37,122,653...37,123,895
Ensembl chr13:37,122,731...37,123,771

MC4R

melanocortin 4 receptor

involved_in
acts_upstream_of_or_within

(MGI:3770192|PMID:16141392)

PMID:16141392

GO_REF:0000107 MGI:3770192

NCBI chr 1:16,131,829...16,132,827
Ensembl chr 1:16,131,589...16,133,079

MYO5A

myosin VA

acts_upstream_of_or_within

(MGI:3589494|PMID:15788565)

PMID:15788565

MGI:3589494

NCBI chr30:17,990,521...18,122,160
Ensembl chr30:17,888,419...18,213,061

NEUROD1

neuronal differentiation 1

involved_in

(PMID:17941991)

PMID:17941991

NCBI chr36:24,853,591...24,857,886

NNAT

neuronatin

acts_upstream_of

(MGI:3614320|PMID:15793245)

PMID:15793245

MGI:3614320

NCBI chr24:26,119,153...26,121,573
Ensembl chr24:26,118,991...26,120,906

PARK7

Parkinsonism associated deglycase

involved_in

(MGI:5908331|PMID:22611253)

PMID:22611253

MGI:5908331

NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303

PCLO

piccolo presynaptic cytomatrix protein

acts_upstream_of_or_within

(MGI:2447935|PMID:12401793)

PMID:12401793

MGI:2447935

NCBI chr18:22,385,102...22,701,944
Ensembl chr18:22,385,100...22,706,793

PDX1

pancreatic and duodenal homeobox 1

involved_in

GO_REF:0000107

NCBI chr25:11,741,863...11,746,885
Ensembl chr25:11,741,863...11,746,885

PRKCE

protein kinase C epsilon

acts_upstream_of
involved_in

(MGI:2675178|PMID:12837755)

PMID:12837755

GO_REF:0000107 MGI:2675178

NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296

PTPRN

protein tyrosine phosphatase receptor type N

involved_in

GO_REF:0000107

NCBI chr37:25,835,590...25,854,050
Ensembl chr37:25,836,118...25,869,931

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692

RAPGEF4

Rap guanine nucleotide exchange factor 4

acts_upstream_of_or_within
involved_in

(MGI:2154654|PMID:11598134), (MGI:2447935|PMID:12401793)

PMID:11598134 PMID:12401793

GO_REF:0000107 MGI:2154654 MGI:2447935

NCBI chr36:17,087,488...17,323,504
Ensembl chr36:17,087,488...17,323,220

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within
involved_in

(MGI:4821020|PMID:20674857)
(MGI:2154654|PMID:11598134)

PMID:11598134 PMID:20674857

MGI:2154654 MGI:4821020

NCBI chr13:4,928,518...5,499,258
Ensembl chr13:4,927,121...5,496,629

SERP1

stress associated endoplasmic reticulum protein 1

acts_upstream_of
involved_in

(MGI:3619104|PMID:16415102)

PMID:19479076 PMID:21873635

PMID:16415102

GO_REF:0000107 MGI:3619104

SLC18A2

solute carrier family 18 member A2

NCBI chr28:27,731,709...27,809,341
Ensembl chr28:27,731,004...27,767,993

SLC30A8

solute carrier family 30 member 8

involved_in

IBA
IEA
ISO

(PMID:21873635)

GO_Central
Ensembl
RGD

GO_REF:0000107 RGD:2315022

NCBI chr13:16,602,255...16,637,299
Ensembl chr13:16,601,912...16,635,880

SMAD2

SMAD family member 2

acts_upstream_of_or_within
involved_in

(MGI:3758991|PMID:17849440)

PMID:17849440

GO_REF:0000107 MGI:3758991

NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983

SNX19

sorting nexin 19

acts_upstream_of_or_within
involved_in

(MGI:5605377|PMID:24843546)
(PMID:24843546)

MGI
GO_Central

PMID:24843546

MGI:5605377

NCBI chr 5:4,044,597...4,085,438
Ensembl chr 5:4,045,097...4,084,363

SREBF1

sterol regulatory element binding transcription factor 1

acts_upstream_of
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776

syntaxin 1A

involved_in

(MGI:3789566|PMID:17502420)

PMID:17502420

MGI:3789566

NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833

STXBP3

syntaxin binding protein 3

involved_in
acts_upstream_of_or_within

(MGI:4352814|PMID:19188424)

PMID:19188424

GO_REF:0000107 MGI:4352814

NCBI chr 6:42,947,639...42,998,297
Ensembl chr 6:42,948,236...43,053,027

SYTL4

synaptotagmin like 4

acts_upstream_of
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr X:74,537,937...74,617,580
Ensembl chr X:74,539,183...74,565,753

VGF

VGF nerve growth factor inducible

acts_upstream_of_or_within
involved_in

(MGI:3770192|PMID:16141392)

PMID:16141392

GO_REF:0000107 MGI:3770192

NCBI chr 6:8,701,289...8,704,386
Ensembl chr 6:8,700,667...8,704,397

insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATG7

autophagy related 7

acts_upstream_of

(MGI:5544155|PMID:24105478)

PMID:24105478

MGI:5544155

NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800

CCDC186

coiled-coil domain containing 186

acts_upstream_of_or_within
involved_in

(MGI:6102228|PMID:27293546)

PMID:27293546

GO_REF:0000107 MGI:6102228

NCBI chr28:24,963,035...25,022,996
Ensembl chr28:24,976,959...25,011,955

CLTRN

collectrin, amino acid transport regulator

acts_upstream_of_positive_effect
involved_in

(PMID:16330323)

PMID:16330323

GO_REF:0000107

NCBI chr X:11,863,479...11,908,361
Ensembl chr X:11,798,839...11,900,594

FKBP1B

FKBP prolyl isomerase 1B

acts_upstream_of
involved_in

(MGI:4421103|PMID:19805579)

PMID:19805579

GO_REF:0000107 MGI:4421103

NCBI chr17:18,534,295...18,544,973
Ensembl chr17:18,534,741...18,544,943

GPR39

G protein-coupled receptor 39

acts_upstream_of

(MGI:4437975|PMID:19213833)

PMID:19213833

MGI:4437975

NCBI chr19:35,385,835...35,585,953
Ensembl chr19:35,385,829...35,586,507

HIF1A

hypoxia inducible factor 1 subunit alpha

acts_upstream_of
involved_in

(MGI:4459348|PMID:20440072)

PMID:20440072

GO_REF:0000107 MGI:4459348

NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692

LOC119880472

peptidyl-prolyl cis-trans isomerase FKBP1B

involved_in

GO_REF:0000107

PTPRN

protein tyrosine phosphatase receptor type N

involved_in

(MGI:3624867|PMID:12031972), (MGI:5141326|PMID:21732083)

PMID:12031972 PMID:21732083

MGI:3624867 MGI:5141326

NCBI chr37:25,835,590...25,854,050
Ensembl chr37:25,836,118...25,869,931

PTPRN2

protein tyrosine phosphatase receptor type N2

involved_in

(MGI:5141326|PMID:21732083)

PMID:21732083

MGI:5141326

NCBI chr16:19,904,468...20,562,585
Ensembl chr16:19,905,473...20,602,680

RAB11B

RAB11B, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:52,955,949...52,966,279
Ensembl chr20:52,956,529...52,965,383

RAB11FIP2

RAB11 family interacting protein 2

involved_in

GO_REF:0000107

NCBI chr28:28,415,139...28,457,215
Ensembl chr28:28,415,639...28,457,286

RAB11FIP5

RAB11 family interacting protein 5

involved_in

(MGI:4352608|PMID:19335615)

PMID:19335615

MGI:4352608

NCBI chr17:49,735,511...49,772,228
Ensembl chr17:49,735,097...49,803,741

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

involved_in
acts_upstream_of_or_within

(MGI:5306883|PMID:21817126)

PMID:21817126

GO_REF:0000107 MGI:5306883

NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090

SELENOT

selenoprotein T

acts_upstream_of_or_within
involved_in

(MGI:5525944|PMID:23913443)

PMID:23913443

GO_REF:0000107 MGI:5525944

NCBI chr23:45,247,088...45,271,229
Ensembl chr23:45,247,088...45,271,228

luteinizing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CGA

glycoprotein hormones, alpha polypeptide

acts_upstream_of_or_within

(MGI:1316794|PMID:12114718)

PMID:12114718

MGI:1316794

NCBI chr12:46,610,801...46,629,322
Ensembl chr12:46,610,973...46,636,640

FOXD1

forkhead box D1

involved_in

(MGI:5484943|PMID:23284914)

T-box transcription factor 3

involved_in

GO_REF:0000107

NCBI chr26:11,694,885...11,709,594
Ensembl chr26:11,696,565...11,708,918

TMF1

TATA element modulatory factor 1

acts_upstream_of_or_within
involved_in

(MGI:5469555|PMID:23000399)

PMID:23000399

GO_REF:0000107 MGI:5469555

NCBI chr20:22,684,150...22,716,107
Ensembl chr20:22,684,159...22,714,432

mast cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2B

adenosine A2b receptor

acts_upstream_of

(MGI:3776334|PMID:11454903)

PMID:11454903

MGI:3776334

NCBI chr 5:39,884,375...39,908,214

ADORA3

adenosine A3 receptor

acts_upstream_of

(MGI:2664591|PMID:12817016)

PMID:12817016

MGI:2664591

NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666

C10orf99

chromosome 10 open reading frame 99

involved_in

GO_REF:0000107

Ensembl chr 4:32,424,531...32,431,812

Cbl proto-oncogene

NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956

CD300A

CD300a molecule

acts_upstream_of

(MGI:3721168|PMID:12874256)

PMID:12874256

MGI:3721168

NCBI chr 9:5,952,428...5,976,328

CHGA

chromogranin A

involved_in

(PMID:21214543)

PMID:21214543

NCBI chr 8:1,970,966...1,973,511

CLNK

cytokine dependent hematopoietic cell linker

involved_in

GO_REF:0000107

NCBI chr 3:68,929,239...69,083,777
Ensembl chr 3:68,881,358...69,080,263

FCER1A

Fc epsilon receptor Ia

acts_upstream_of
involved_in

PMID:8551243 PMID:9000133

(MGI:85068|PMID:9000133)
(PMID:8551243)

MGI
UniProt

MGI:85068

NCBI chr38:22,683,478...22,688,842
Ensembl chr38:22,683,477...22,690,763

FCER1G

Fc epsilon receptor Ig

acts_upstream_of

(MGI:3029067|PMID:14764707)

PMID:14764707

MGI:3029067

NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940

GPR15LG

G protein-coupled receptor 15 ligand

involved_in

GO_REF:0000107

NCBI chr 4:32,426,663...32,432,103

GRP

gastrin releasing peptide

involved_in

UniProt
Ensembl

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr 1:16,974,818...16,987,578
Ensembl chr 1:16,975,113...16,987,531

KIT

KIT proto-oncogene, receptor tyrosine kinase

involved_in

UniProt
Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029

MILR1

mast cell immunoglobulin like receptor 1

involved_in

GO_REF:0000002

NCBI chr 9:12,251,085...12,266,608
Ensembl chr 9:12,251,186...12,266,605

MRGPRX

MAS related GPR family member X

involved_in

(PMID:22069323)

PMID:22069323

NCBI chr21:41,195,255...41,235,734

NR4A3

nuclear receptor subfamily 4 group A member 3

involved_in

(MGI:5586645|PMID:24586680)

PMID:24586680

MGI:5586645

NCBI chr11:56,806,506...56,846,997
Ensembl chr11:56,812,804...56,847,689

PLA2G3

phospholipase A2 group III

involved_in
acts_upstream_of_or_within

(MGI:5492190|PMID:23624557)

PMID:23624557

GO_REF:0000107 MGI:5492190

NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508

PTGDS

prostaglandin D2 synthase

involved_in

GO_REF:0000043

NCBI chr 9:48,647,334...48,650,608
Ensembl chr 9:48,646,255...48,669,814

RAB44

RAB44, member RAS oncogene family

acts_upstream_of_or_within
involved_in

(MGI:6693988|PMID:32238914)

PMID:32238914

GO_REF:0000107 MGI:6693988

NCBI chr12:5,769,056...5,804,963
Ensembl chr12:5,770,882...5,804,949

RABGEF1

RAB guanine nucleotide exchange factor 1

acts_upstream_of

(MGI:3050742|PMID:15235600)

PMID:15235600

MGI:3050742

NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547

RASGRP1

RAS guanyl releasing protein 1

acts_upstream_of_or_within
involved_in

(MGI:3758152|PMID:17190838)

PMID:17190838

GO_REF:0000107 MGI:3758152

NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810

SCN11A

sodium voltage-gated channel alpha subunit 11

involved_in

GO_REF:0000107

NCBI chr23:8,559,804...8,651,448
Ensembl chr23:8,559,952...8,651,500

SYK

spleen associated tyrosine kinase

acts_upstream_of
involved_in

(MGI:85068|PMID:9000133)

PMID:9000133

GO_REF:0000107 MGI:85068

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

natural killer cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CORO1A

coronin 1A

involved_in

GO_REF:0000107

NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818

LOC478984

low affinity immunoglobulin gamma Fc region receptor III

involved_in

(PMID:25786175), (PMID:28652325)

PMID:25786175 PMID:28652325

NCBI chr38:21,054,870...21,060,948

NKG7

natural killer cell granule protein 7

involved_in

(MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019)

PMID:32839608 PMID:33911019

MGI:6506882 MGI:6810811

NCBI chr 1:105,607,558...105,608,870

RAB27A, member RAS oncogene family

involved_in
acts_upstream_of_or_within

(MGI:3653524|PMID:11266473)

PMID:11266473

GO_REF:0000107 MGI:3653524

NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521

STX11

syntaxin 11

acts_upstream_of_or_within

(MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531)

PMID:23042080 PMID:23190531

MGI:5460953 MGI:5471188

NCBI chr 1:35,600,440...35,645,421
Ensembl chr 1:35,601,133...35,644,819

UNC13D

unc-13 homolog D

involved_in
acts_upstream_of_or_within

(MGI:3703574|PMID:17420270)

PMID:17420270

GO_REF:0000107 MGI:3703574

NCBI chr 9:4,753,300...4,766,751
Ensembl chr 9:4,753,166...4,766,756

vesicle associated membrane protein 2

NOT|involved_in

(PMID:18042464)

PMID:18042464

NCBI chr 5:32,975,372...32,977,967

vesicle associated membrane protein 7

involved_in

(PMID:18042464)

PMID:18042464

NCBI chr X:123,717,524...123,783,781
Ensembl chr X:123,717,446...123,783,014

negative regulation of acetylcholine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HTR6

5-hydroxytryptamine receptor 6

NCBI chr 2:79,022,790...79,033,975
Ensembl chr 2:79,022,775...79,033,975

negative regulation of adiponectin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL1B

interleukin 1 beta

involved_in

(MGI:3828398|PMID:16865359)

PMID:16865359

MGI:3828398

NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458

RAB11FIP1

RAB11 family interacting protein 1

involved_in

GO_REF:0000107

NCBI chr16:27,503,051...27,534,123
Ensembl chr16:27,503,113...27,531,935

RAB11FIP3

RAB11 family interacting protein 3

involved_in

GO_REF:0000107

NCBI chr 6:40,020,673...40,100,229
Ensembl chr 6:40,021,805...40,047,273

RAB11FIP5

RAB11 family interacting protein 5

involved_in

(PMID:24040321)

CACAO

PMID:24040321

NCBI chr17:49,735,511...49,772,228
Ensembl chr17:49,735,097...49,803,741

negative regulation of BMP secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MIR140

microRNA mir-140

acts_upstream_of

(PMID:24928442)

PMID:24928442

NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326

MIR17

microRNA mir-17

acts_upstream_of

(PMID:23399447)

PMID:23399447

NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083

MIR214

microRNA mir-214

acts_upstream_of

(PMID:30703347)

PMID:30703347

NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670

MIR93

microRNA mir-93

acts_upstream_of

(PMID:28797104)

PMID:28797104

NCBI chr 6:9,498,780...9,498,840

MIR98

microRNA mir-98

acts_upstream_of

(PMID:27860183)

PMID:27860183

NCBI chr X:45,253,693...45,253,772
Ensembl chr X:45,253,696...45,253,775

negative regulation of calcium ion-dependent exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADRA2A

adrenoceptor alpha 2A

involved_in

PMID:19965390

NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684

CBARP

CACN subunit beta associated regulatory protein

involved_in

(PMID:21873635)

NCBI chr20:57,554,162...57,559,126
Ensembl chr20:57,554,032...57,559,612

GNAI2

G protein subunit alpha i2

NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697

LOC481709

POU domain, class 5, transcription factor 1

involved_in

GO_REF:0000107

NCBI chr12:860,702...866,099

NOTCH1

notch receptor 1

acts_upstream_of_or_within
involved_in

(MGI:3841508|PMID:19251639)

PMID:19251639

GO_REF:0000107 MGI:3841508

NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277

POU5F1

POU class 5 homeobox 1

acts_upstream_of_or_within

(MGI:59016|PMID:2357966)

RAP1B, member of RAS oncogene family

acts_upstream_of_or_within
involved_in

(MGI:5490391|PMID:23616533)

PMID:23616533

GO_REF:0000107 MGI:5490391

NCBI chr10:10,805,359...10,816,839
Ensembl chr10:10,805,357...10,815,575

REST

RE1 silencing transcription factor

involved_in

GO_REF:0000024

NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388

STXBP3

syntaxin binding protein 3

involved_in

GO_REF:0000107

NCBI chr 6:42,947,639...42,998,297
Ensembl chr 6:42,948,236...43,053,027

synaptotagmin 4

NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714

TRIM9

tripartite motif containing 9

NCBI chr 8:27,334,045...27,441,238
Ensembl chr 8:27,336,063...27,441,445

negative regulation of catecholamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHGA

chromogranin A

involved_in

(PMID:15326220)

PMID:15326220

NCBI chr 8:1,970,966...1,973,511

synaptotagmin 4

involved_in

GO_REF:0000107

NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714

negative regulation of constitutive secretory pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB33B

RAB33B, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr19:3,256,790...3,273,198
Ensembl chr19:3,259,119...3,274,153

negative regulation of corticosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

neuregulin 1

NCBI chr16:31,697,958...32,771,888
Ensembl chr16:31,706,851...32,771,932

translocator protein

NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297

negative regulation of corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CRHBP

corticotropin releasing hormone binding protein

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 3:29,726,316...29,737,748
Ensembl chr 3:29,705,031...29,758,111

negative regulation of cortisol secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within
involved_in

(MGI:3513751|PMID:15520383)

GO_REF:0000107 MGI:3513751

NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481

negative regulation of cytotoxic T cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CEACAM1

CEA cell adhesion molecule 1

involved_in

(PMID:18424730)

PMID:18424730

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

NCKAP1L

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

negative regulation of dense core granule exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 4

involved_in

PMID:20303854

NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714

negative regulation of dopamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

NCBI chr 6:33,385,779...33,471,348
Ensembl chr 6:33,376,996...33,471,326

complement C5

NCBI chr11:73,953,727...74,029,919
Ensembl chr11:73,953,727...74,029,851

CNR1

cannabinoid receptor 1

NCBI chr12:47,537,240...47,560,723
Ensembl chr12:47,509,583...47,560,983

dopamine receptor D2

NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939

GABBR1

gamma-aminobutyric acid type B receptor subunit 1

NCBI chr35:26,212,274...26,243,910
Ensembl chr35:26,213,076...26,237,572

myosin VA

NCBI chr30:17,990,521...18,122,160
Ensembl chr30:17,888,419...18,213,061

SYT11

synaptotagmin 11

involved_in

GO_REF:0000107

NCBI chr 7:41,910,102...41,929,020
Ensembl chr 7:41,912,920...41,929,617

negative regulation of eosinophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCR2

C-C motif chemokine receptor 2

involved_in

GO_REF:0000107

NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698

negative regulation of epinephrine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone

involved_in

GO_Central
GO_Central
RGD

(PMID:21873635)

PMID:12606499 PMID:21873635

RGD:704397

NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384

CRHR1

corticotropin releasing hormone receptor 1

NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402

corticotropin releasing hormone receptor 2

NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142

GABBR1

gamma-aminobutyric acid type B receptor subunit 1

NCBI chr35:26,212,274...26,243,910
Ensembl chr35:26,213,076...26,237,572

GCK

glucokinase

down-regulation of the counterregulatory response to insulin-induced hypoglycemia

prostaglandin-endoperoxide synthase 1

NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819

negative regulation of exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

DDI2

DNA damage inducible 1 homolog 2

involved_in

GO_REF:0000002

NCBI chr 2:81,915,613...81,957,803

IL1RAPL1

interleukin 1 receptor accessory protein like 1

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr X:23,747,689...25,105,606
Ensembl chr X:23,943,871...25,099,377

SNCA

synuclein alpha

involved_in

GO_REF:0000107

NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383

TCP11

t-complex 11

involved_in

(MGI:1097498|PMID:9322250), (MGI:5816449|PMID:9820206)

PMID:9322250 PMID:9820206

MGI:1097498 MGI:5816449

NCBI chr12:4,286,863...4,306,152
Ensembl chr12:4,286,876...4,306,273

negative regulation of exosomal secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP9A

ATPase phospholipid transporting 9A (putative)

involved_in

GO_REF:0000107

NCBI chr24:37,797,150...37,912,031
Ensembl chr24:37,800,281...37,911,890

PRKN

parkin RBR E3 ubiquitin protein ligase

involved_in

GO_REF:0000107

NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764

RAB7A

RAB7A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr20:2,704,716...2,776,518
Ensembl chr20:2,704,752...2,826,636

VPS4B

vacuolar protein sorting 4 homolog B

involved_in

GO_REF:0000107

NCBI chr 1:13,638,965...13,673,295
Ensembl chr 1:13,639,004...13,669,072

negative regulation of extracellular matrix constituent secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADTRP

androgen dependent TFPI regulating protein

involved_in

GO_REF:0000107

NCBI chr35:11,300,186...11,362,893
Ensembl chr35:11,300,887...11,362,101

NOTCH1

notch receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277

TNFRSF1A

TNF receptor superfamily member 1A

involved_in

(MGI:6158728|PMID:26491108)

PMID:26491108

MGI:6158728

NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282

TNFRSF1B

TNF receptor superfamily member 1B

involved_in

GO_REF:0000107

NCBI chr 2:84,140,179...84,151,219
Ensembl chr 2:84,141,911...84,157,191

negative regulation of follicle-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone receptor 2

NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142

INHA

inhibin subunit alpha

immature male rats
female rats during diestrus-1

PMID:2500324 PMID:8015360

RGD:2290442 RGD:2290444

NCBI chr37:26,080,465...26,083,570
Ensembl chr37:26,080,510...26,083,391

INHBB

inhibin subunit beta B

involved_in

GO_REF:0000107

NCBI chr19:29,765,697...29,768,485
Ensembl chr19:29,767,682...29,768,077

urocortin 2

NCBI chr20:40,551,060...40,552,920

negative regulation of glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CART prepropeptide

NCBI chr 2:54,865,043...54,867,410
Ensembl chr 2:54,865,298...54,867,158

corticotropin releasing hormone

involved_in

GO_Central
GO_Central
RGD

(PMID:21873635)

PMID:12606499 PMID:21873635

RGD:704397

NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384

FAM3D

FAM3 metabolism regulating signaling molecule D

involved_in

GO_REF:0000002

NCBI chr20:32,013,920...32,040,599
Ensembl chr20:32,013,974...32,040,490

LEP

leptin

involved_in

GO_REF:0000107

NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395

nucleobindin 2

NCBI chr21:39,868,756...39,918,724
Ensembl chr21:39,874,781...39,918,689

negative regulation of glucocorticoid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CRY1

cryptochrome circadian regulator 1

involved_in

GO_REF:0000107

NCBI chr10:31,681,098...31,792,995
Ensembl chr10:31,681,288...31,780,306

CRY2

cryptochrome circadian regulator 2

involved_in

GO_REF:0000107

NCBI chr18:43,538,335...43,573,651
Ensembl chr18:43,539,612...43,573,875

negative regulation of glutamate secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA1

adenosine A1 receptor

K+-evoked glutamate release

PMID:16481441

RGD:1625231

NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051

GRM7

glutamate metabotropic receptor 7

PMID:11825890 PMID:12692128

RGD:2289010 RGD:728749

NCBI chr20:10,230,568...11,058,693
Ensembl chr20:10,230,557...11,058,703

HRH3

histamine receptor H3

NCBI chr24:46,239,883...46,243,123

HRH3

histamine receptor H3

involved_in

(PMID:21873635)

Ensembl chr24:46,240,971...46,243,281

HTR6

5-hydroxytryptamine receptor 6

NCBI chr 2:79,022,790...79,033,975
Ensembl chr 2:79,022,775...79,033,975

interleukin 1 beta

NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458

IL1RN

interleukin 1 receptor antagonist

NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329

NPY5R

neuropeptide Y receptor Y5

NCBI chr15:59,600,212...59,608,576
Ensembl chr15:59,606,902...59,608,273

PRKG1

protein kinase cGMP-dependent 1

NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729

TRH

thyrotropin releasing hormone

involved_in

PMID:16055093 PMID:21873635

(PMID:21873635)

GO_Central
RGD

RGD:1600422

NCBI chr20:5,219,495...5,222,914
Ensembl chr20:5,219,594...5,222,866

negative regulation of gonadotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GJA1

gap junction protein alpha 1

involved_in

GO_REF:0000107

NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936

NPVF

neuropeptide VF precursor

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr14:38,652,870...38,656,241
Ensembl chr14:38,652,870...38,656,241

negative regulation of growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KALRN

kalirin RhoGEF kinase

acts_upstream_of_or_within
involved_in

(MGI:5551307|PMID:23116210)

PMID:23116210

GO_REF:0000107 MGI:5551307

NCBI chr33:27,161,403...27,752,891
Ensembl chr33:27,161,504...27,746,497

MADD

MAP kinase activating death domain

NCBI chr18:42,290,226...42,332,237
Ensembl chr18:42,290,754...42,328,586

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within
involved_in

(MGI:3513751|PMID:15520383)

GO_REF:0000107 MGI:3513751

NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481

sirtuin 1

NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279

SSTR1

somatostatin receptor 1

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr 8:16,571,069...16,575,730

SSTR2

somatostatin receptor 2

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr 9:6,989,488...7,004,851
Ensembl chr 9:6,996,874...7,000,778

SSTR3

somatostatin receptor 3

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr10:27,324,067...27,332,570
Ensembl chr10:27,329,174...27,330,451

negative regulation of hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844

ADORA1

adenosine A1 receptor

gastrin

NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051

endothelin 1

NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383

endothelin 2

NCBI chr15:1,647,966...1,654,272
Ensembl chr15:1,648,077...1,654,272

endothelin 3

NCBI chr24:44,024,553...44,054,727
Ensembl chr24:44,033,419...44,054,050

FGF23

fibroblast growth factor 23

involved_in

PMID:17992255

NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766

IL11

interleukin 11

acts_upstream_of_or_within
involved_in

(PMID:7867561)

GO_REF:0000107

NCBI chr 1:102,311,960...102,319,102
Ensembl chr 1:102,316,105...102,318,653

IL6

interleukin 6

acts_upstream_of_or_within

(MGI:71439|PMID:7867561)

MGI:71439

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

LIF

LIF interleukin 6 family cytokine

acts_upstream_of_or_within
involved_in

(PMID:7867561)

GO_REF:0000107

NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851

NMB

neuromedin B

thyrotropin (TSH); anterior pituitary gland of euthyroid and hyperthyroid rats

PMID:1557409

RGD:1642347

NCBI chr 3:53,927,891...53,931,129
Ensembl chr 3:53,927,900...53,931,069

NPY1R

neuropeptide Y receptor Y1

NCBI chr15:59,580,546...59,587,753
Ensembl chr15:59,580,809...59,583,237

OSM

oncostatin M

acts_upstream_of_or_within
involved_in

(PMID:7867561)

GO_REF:0000107

NCBI chr26:23,421,787...23,439,332
Ensembl chr26:23,421,787...23,426,036

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within
involved_in

(MGI:3513751|PMID:15520383)

GO_REF:0000107 MGI:3513751

NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481

urocortin

ghrelin

NCBI chr17:21,278,512...21,280,404
Ensembl chr17:21,278,932...21,279,312

negative regulation of insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCC8

ATP binding cassette subfamily C member 8

involved_in

PMID:15163199 PMID:16924481 PMID:25771886

(MGI:3831492|PMID:16924481)
(MGI:7333031|PMID:25771886)

RGD
MGI

MGI:3831492 MGI:7333031 RGD:1598646

NCBI chr21:39,963,001...40,037,040
Ensembl chr21:39,962,947...40,036,981

ACVR1C

activin A receptor type 1C

acts_upstream_of_or_within
involved_in

(MGI:3796011|PMID:18480258)

PMID:18480258

GO_REF:0000107 MGI:3796011

NCBI chr36:3,534,231...3,583,310
Ensembl chr36:3,541,248...3,613,384

ADRA2A

adrenoceptor alpha 2A

involved_in

GO_REF:0000107

NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684

CCN3

cellular communication network factor 3

involved_in

GO_REF:0000107

NCBI chr13:18,507,586...18,515,755
Ensembl chr13:18,507,580...18,514,619

dopamine receptor D2

NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180

FAM3D

FAM3 metabolism regulating signaling molecule D

involved_in

UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr20:32,013,920...32,040,599
Ensembl chr20:32,013,974...32,040,490

FBN1

fibrillin 1

involved_in

(MGI:6442875|PMID:30997682)

PMID:30997682

MGI:6442875

NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151

FFAR2

free fatty acid receptor 2

involved_in

GO_REF:0000107

NCBI chr 1:117,197,535...117,201,613
Ensembl chr 1:117,198,289...117,199,284

FFAR3

free fatty acid receptor 3

involved_in

(MGI:5909396|PMID:26091414), (MGI:6450661|PMID:32073900)
(MGI:5704028|PMID:25581519)

PMID:25581519 PMID:26091414 PMID:32073900

MGI:5704028 MGI:5909396 MGI:6450661

NCBI chr 1:117,251,604...117,257,048

involved_in

GO_REF:0000107

forkhead box O1

involved_in

(MGI:2388494|PMID:12219087), (MGI:6101624|PMID:27457971)

PMID:12219087 PMID:27457971

MGI:2388494 MGI:6101624

NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825

GHRL

ghrelin and obestatin prepropeptide

involved_in
acts_upstream_of_or_within

ISS
IEA
ISO

PMID:17130496
(MGI:3709118|PMID:17130496)

UniProt
Ensembl
UniProt
MGI

PMID:17130496

GO_REF:0000024 GO_REF:0000107 MGI:3709118 RGD:8553721

NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510

growth hormone secretagogue receptor

acts_upstream_of_or_within

PMID:17130496

NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312

GNAO1

G protein subunit alpha o1

involved_in

(MGI:4887503|PMID:21220323)
(MGI:4941424|PMID:20622165)

PMID:20622165 PMID:21220323

MGI:4887503 MGI:4941424

NCBI chr 2:59,805,675...59,980,782
Ensembl chr 2:59,806,689...59,980,398

GNAZ

G protein subunit alpha z

involved_in

(MGI:3775331|PMID:18096703)

PMID:18096703

MGI:3775331

NCBI chr26:27,780,598...27,811,688
Ensembl chr26:27,781,704...27,810,188

HADH

hydroxyacyl-CoA dehydrogenase

NCBI chr32:28,460,445...28,506,141
Ensembl chr32:28,460,193...28,531,280

HDAC1

histone deacetylase 1

NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186

INHBB

inhibin subunit beta B

acts_upstream_of_or_within
involved_in

(MGI:3796011|PMID:18480258)

PMID:18480258

GO_REF:0000107 MGI:3796011

NCBI chr19:29,765,697...29,768,485
Ensembl chr19:29,767,682...29,768,077

IRS1

insulin receptor substrate 1

involved_in

GO_REF:0000107

NCBI chr25:39,624,554...39,687,991

KCNB1

potassium voltage-gated channel subfamily B member 1

involved_in

GO_REF:0000107

NCBI chr24:36,016,800...36,118,873
Ensembl chr24:36,025,472...36,117,934

KCNJ11

potassium inwardly rectifying channel subfamily J member 11

involved_in

GO_REF:0000107

NCBI chr21:39,953,461...39,957,615
Ensembl chr21:39,955,551...39,956,723

KCNQ1

potassium voltage-gated channel subfamily Q member 1

NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043

MIDN

midnolin

acts_upstream_of_or_within

PMID:24187134

NCBI chr20:57,535,165...57,543,014
Ensembl chr20:57,536,880...57,542,977

MTNR1A

melatonin receptor 1A

NCBI chr16:44,258,239...44,286,761

MTNR1B

melatonin receptor 1B

NCBI chr21:7,639,532...7,643,534
Ensembl chr21:7,640,317...7,641,498

NOS1

nitric oxide synthase 1

NCBI chr26:13,787,341...13,895,176
Ensembl chr26:13,786,309...13,962,332

phosphodiesterase 8B

NCBI chr 3:29,289,867...29,432,557
Ensembl chr 3:29,291,549...29,432,542

PFKL

phosphofructokinase, liver type

acts_upstream_of_or_within
involved_in

(MGI:1096000|PMID:9287040)

PMID:9287040

GO_REF:0000107 MGI:1096000

NCBI chr31:38,153,638...38,178,741
Ensembl chr31:38,156,451...38,178,507

PPP3CA

protein phosphatase 3 catalytic subunit alpha

involved_in

PMID:19965390

NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688

PRKN

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within
involved_in

(PMID:24187134)

PMID:24187134

GO_REF:0000107

NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764

PSMD9

proteasome 26S subunit, non-ATPase 9

involved_in

PMID:16099819

NCBI chr26:7,376,154...7,400,655
Ensembl chr26:7,377,413...7,400,573

PTGER3

prostaglandin E receptor 3

NCBI chr 6:74,932,789...74,986,573

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within
involved_in

(MGI:3513751|PMID:15520383)

GO_REF:0000107 MGI:3513751

NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481

REST

RE1 silencing transcription factor

involved_in

GO_REF:0000024

NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388

RPTOR

regulatory associated protein of MTOR complex 1

involved_in

(MGI:5619445|PMID:23092880)

CACAO

PMID:23092880

MGI:5619445

NCBI chr 9:1,012,512...1,345,872
Ensembl chr 9:1,013,603...1,344,148

SFRP1

secreted frizzled related protein 1

involved_in

GO_REF:0000107

NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964

SIRT4

sirtuin 4

acts_upstream_of_or_within
involved_in

(MGI:3769241|PMID:16959573)

PMID:16959573

GO_REF:0000107 MGI:3769241

NCBI chr26:16,228,831...16,244,104
Ensembl chr26:16,234,710...16,240,012

SREBF1

sterol regulatory element binding transcription factor 1

acts_upstream_of_or_within
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776

STXBP5L

syntaxin binding protein 5L

acts_upstream_of_or_within
involved_in

(MGI:5296997|PMID:21998599)

PMID:21998599

GO_REF:0000107 MGI:5296997

NCBI chr33:24,320,625...24,702,782
Ensembl chr33:24,320,650...24,697,153

SYTL4

synaptotagmin like 4

acts_upstream_of_or_within
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr X:74,537,937...74,617,580
Ensembl chr X:74,539,183...74,565,753

urotensin 2

NCBI chr 5:61,503,268...61,508,146

VSNL1

visinin like 1

acts_upstream_of_or_within
involved_in

(MGI:3694336|PMID:16731532)

PMID:16731532

GO_REF:0000107 MGI:3694336

NCBI chr17:13,022,232...13,109,590

negative regulation of insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADRA2A

adrenoceptor alpha 2A

involved_in

GO_REF:0000107

NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684

corticotropin releasing hormone receptor 2

NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142

ENY2

ENY2 transcription and export complex 2 subunit

NCBI chr13:9,895,537...9,905,081
Ensembl chr13:9,895,630...9,905,301

FKBP1B

FKBP prolyl isomerase 1B

acts_upstream_of_or_within
involved_in

(MGI:4421103|PMID:19805579)

PMID:19805579

GO_REF:0000107 MGI:4421103

NCBI chr17:18,534,295...18,544,973
Ensembl chr17:18,534,741...18,544,943

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294

jagunal homolog 1

NCBI chr20:8,372,981...8,376,089
Ensembl chr20:8,373,316...8,376,085

KLF7

KLF transcription factor 7

involved_in

GO_REF:0000107

NCBI chr37:15,515,563...15,607,345
Ensembl chr37:15,521,622...15,605,824

LOC119880472

peptidyl-prolyl cis-trans isomerase FKBP1B

involved_in

GO_REF:0000107

MAP4K4

mitogen-activated protein kinase kinase kinase kinase 4

NCBI chr10:41,088,020...41,276,801
Ensembl chr10:41,089,371...41,276,891

NDUFAF2

NADH:ubiquinone oxidoreductase complex assembly factor 2

involved_in
acts_upstream_of_or_within

(MGI:5467193|PMID:22587331)

PMID:22587331

GO_REF:0000107 MGI:5467193

NCBI chr 2:47,559,002...47,706,704
Ensembl chr 2:47,559,111...47,706,696

phosphodiesterase 1C

NCBI chr14:44,250,612...44,543,818
Ensembl chr14:44,145,534...44,644,937

phosphodiesterase 3B

NCBI chr21:37,364,940...37,532,152
Ensembl chr21:37,364,623...37,530,597

phosphodiesterase 4C

NCBI chr20:44,767,187...44,792,887
Ensembl chr20:44,742,161...44,791,053

phosphodiesterase 8B

NCBI chr 3:29,289,867...29,432,557
Ensembl chr 3:29,291,549...29,432,542

PIM3

Pim-3 proto-oncogene, serine/threonine kinase

involved_in

GO_REF:0000107

NCBI chr10:17,260,590...17,262,175

PTPMT1

protein tyrosine phosphatase mitochondrial 1

NCBI chr18:42,081,414...42,087,435
Ensembl chr18:42,081,262...42,087,423

TBC1D1

TBC1 domain family member 1

NCBI chr 3:74,077,477...74,316,725
Ensembl chr 3:73,992,452...74,316,894

uncoupling protein 2

NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128

negative regulation of luteinizing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone

NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384

corticotropin releasing hormone receptor 2

NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142

OPRK1

opioid receptor kappa 1

NCBI chr29:5,022,270...5,054,223
Ensembl chr29:5,025,786...5,051,919

TACR2

tachykinin receptor 2

NCBI chr 4:20,518,797...20,531,118
Ensembl chr 4:20,517,563...20,531,867

urocortin 2

NCBI chr20:40,551,060...40,552,920

negative regulation of mast cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD300A

CD300a molecule

involved_in
acts_upstream_of_or_within

PMID:12874256 PMID:16339535

(PMID:16339535)
(MGI:3721168|PMID:12874256)

UniProt
MGI

MGI:3721168

NCBI chr 9:5,952,428...5,976,328

CD84

CD84 molecule

involved_in

GO_REF:0000107

NCBI chr38:21,702,788...21,727,373
Ensembl chr38:21,702,494...21,759,668

FOXF1

forkhead box F1

acts_upstream_of_or_within
involved_in

(MGI:4367570|PMID:18421012)

PMID:18421012

GO_REF:0000107 MGI:4367570

NCBI chr 5:66,343,776...66,347,785
Ensembl chr 5:66,345,150...66,347,935

heme oxygenase 1

NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773

IL13RA2

interleukin 13 receptor subunit alpha 2

acts_upstream_of_or_within
involved_in

(MGI:3589858|PMID:15944273)

PMID:15944273

GO_REF:0000107 MGI:3589858

NCBI chr X:87,747,373...87,776,797
Ensembl chr X:87,747,373...87,776,798

LGALS9

galectin 9

involved_in

(PMID:24465902)

PMID:24465902

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

RABGEF1

RAB guanine nucleotide exchange factor 1

acts_upstream_of_or_within

(MGI:3050742|PMID:15235600)

PMID:15235600

MGI:3050742

NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547

negative regulation of matrix metallopeptidase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD200

CD200 molecule

involved_in

GO_REF:0000107

NCBI chr33:16,872,849...16,892,161
Ensembl chr33:16,873,048...16,890,954

IDH2

isocitrate dehydrogenase (NADP(+)) 2

NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496

MIR199-1

microRNA mir-199-1

involved_in

(PMID:28358369)

PMID:28358369

NCBI chr20:50,410,924...50,410,984
Ensembl chr20:50,410,913...50,410,994

MIR199-2

microRNA mir-199-2

involved_in

(PMID:28358369)

PMID:28358369

NCBI chr 7:26,812,766...26,812,824
Ensembl chr 7:26,812,735...26,812,838

MIR199-3

microRNA mir-199-3

involved_in

(PMID:28358369)

PMID:28358369

NCBI chr 9:55,262,354...55,262,412
Ensembl chr 9:55,262,328...55,262,437

MIR19A

microRNA mir-19a

acts_upstream_of

(PMID:28078022)
(PMID:22105995)

PMID:22105995 PMID:28078022

NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366

MIR19B-1

microRNA mir-19b-1

acts_upstream_of

(PMID:22105995)

PMID:22105995

NCBI chr22:42,478,598...42,478,656

MIR19B-2

microRNA mir-19b-2

acts_upstream_of

(PMID:22105995)

PMID:22105995

NCBI chr X:104,895,962...104,896,025
Ensembl chr X:104,895,962...104,896,025

negative regulation of natural killer cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DLA-79

MHC class Ib

involved_in

(PMID:24018270)

PMID:24018270

NCBI chr18:41,142,312...41,170,018
Ensembl chr18:41,142,307...41,170,100

LGALS9

galectin 9

involved_in

(MGI:5491117|PMID:23408620)

PMID:23408620

MGI:5491117

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

negative regulation of neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASIC1

acid sensing ion channel subunit 1

acts_upstream_of_or_within
involved_in

(MGI:3841883|PMID:18094106)

PMID:18094106

GO_REF:0000107 MGI:3841883

NCBI chr27:4,638,826...4,663,352
Ensembl chr27:4,638,812...4,648,038

NF1

neurofibromin 1

acts_upstream_of_or_within
involved_in

(MGI:3612345|PMID:16298082)

PMID:16298082

GO_REF:0000107 MGI:3612345

NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382

PNKD

PNKD metallo-beta-lactamase domain containing

acts_upstream_of_or_within
involved_in

(MGI:5634213|PMID:25730884)

PMID:25730884

GO_REF:0000107 MGI:5634213

NCBI chr37:24,948,763...25,008,542
Ensembl chr37:24,948,932...25,005,144

SLC30A1

solute carrier family 30 member 1

involved_in

PMID:16741752

NCBI chr 7:9,952,373...9,959,382
Ensembl chr 7:9,955,877...9,959,388

synaptotagmin 4

involved_in

PMID:10397765

NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714

negative regulation of neutrophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABR

ABR activator of RhoGEF and GTPase

acts_upstream_of_or_within

(MGI:4366690|PMID:19703997)

PMID:19703997

MGI:4366690

NCBI chr 9:44,634,117...44,821,454
Ensembl chr 9:44,681,411...44,819,249

BCR

BCR activator of RhoGEF and GTPase

acts_upstream_of_or_within
involved_in

(MGI:4366690|PMID:19703997)

PMID:19703997

GO_REF:0000107 MGI:4366690

NCBI chr26:27,856,280...27,980,923
Ensembl chr26:27,856,082...27,978,318

SPI1

Spi-1 proto-oncogene

involved_in

GO_REF:0000107

NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727

negative regulation of norepinephrine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGTR2

angiotensin II receptor type 2

NCBI chr X:88,703,551...88,708,451
Ensembl chr X:88,705,765...88,706,853

complement C5

NCBI chr11:73,953,727...74,029,919
Ensembl chr11:73,953,727...74,029,851

corticotropin releasing hormone

NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384

corticotropin releasing hormone receptor 2

NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142

growth hormone secretagogue receptor

NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312

P2RY1

purinergic receptor P2Y1

NCBI chr23:47,249,496...47,253,203
Ensembl chr23:47,249,496...47,253,203

P2RY12

purinergic receptor P2Y12

NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526

PTGER3

prostaglandin E receptor 3

NCBI chr 6:74,932,789...74,986,573

PTGS1

prostaglandin-endoperoxide synthase 1

NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819

negative regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MADD

MAP kinase activating death domain

NCBI chr18:42,290,226...42,332,237
Ensembl chr18:42,290,754...42,328,586

negative regulation of peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PPARG

peroxisome proliferator activated receptor gamma

involved_in

(MGI:5486574|PMID:11387233)

PMID:11387233

MGI:5486574

NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981

negative regulation of progesterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

microRNA mir-222

NCBI chr X:39,524,519...39,524,608
Ensembl chr X:39,524,519...39,524,608

TP53

tumor protein p53

involved_in

(PMID:18703674)

PMID:18703674

NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109

negative regulation of prolactin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A5

NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378

negative regulation of prostaglandin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACSL4

acyl-CoA synthetase long chain family member 4

involved_in

(PMID:21242590)

PMID:21242590

NCBI chr X:82,864,506...82,943,984
Ensembl chr X:82,866,823...82,916,789

ATP5PF

ATP synthase peripheral stalk subunit F6