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Term:SREBP-SCAP-Insig complex
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Accession:GO:0032937 term browser browse the term
Definition:A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.

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SREBP-SCAP-Insig complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07060293.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:67,330,588...67,331,346 JBrowse link
G Insig1 insulin induced gene 1 part_of ISO
(PMID:12202038), (PMID:15899885)
RGD PMID:12202038 PMID:15899885 PMID:21873635 RGD:13792537 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 part_of ISO
RGD PMID:12242332 PMID:21873635 RGD:13792537 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 part_of IEA
(PMID:12202038), (PMID:12242332)
PMID:12202038 PMID:12242332 GO_REF:0000107 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      endoplasmic reticulum protein-containing complex 138
        SREBP-SCAP-Insig complex 4
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      organelle 13017
        intracellular organelle 12666
          intracellular membrane-bounded organelle 11161
            endoplasmic reticulum 1756
              endoplasmic reticulum subcompartment 959
                endoplasmic reticulum membrane 949
                  intrinsic component of endoplasmic reticulum membrane 151
                    integral component of endoplasmic reticulum membrane 143
                      SREBP-SCAP-Insig complex 4
paths to the root