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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of activin receptor signaling pathway
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Accession:GO:0032926 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
Synonyms:exact_synonym: down regulation of activin receptor signaling pathway;   downregulation of activin receptor signaling pathway;   negative regulation of activin receptor signalling pathway
 narrow_synonym: inhibition of activin receptor signaling pathway
 related_synonym: negative regulation of activin signaling pathway;   negative regulation of activin signalling pathway



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negative regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:9884026)
GO_REF:0000107
RGD
Ensembl
PMID:9884026 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO (PMID:9660951)
(MGI:1858315|PMID:10748465)
RGD PMID:9660951 PMID:10748465 MGI:1858315 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:16720724) RGD PMID:16720724 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fst follistatin involved_in ISO
IBA
(PMID:11948405), (PMID:12697670), (PMID:12702211)
GO_REF:0000033
RGD
GO_Central
PMID:11948405 PMID:12697670 PMID:12702211 GO_REF:0000033 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fstl3 follistatin like 3 involved_in ISO
IEA
IBA
(PMID:11948405), (PMID:12697670)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:11948405 PMID:12697670 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Igsf1 immunoglobulin superfamily, member 1 involved_in ISO
IEA
(PMID:11266516)
GO_REF:0000107
RGD
Ensembl
PMID:11266516 GO_REF:0000107 NCBI chr  X:129,069,891...129,085,331
Ensembl chr  X:129,069,896...129,085,139
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:56,415,053...56,499,047
Ensembl chr 7:56,305,448...56,502,474
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:1353670|PMID:10681527)
UniProt
RGD
PMID:10681527 GO_REF:0000024 MGI:1353670 NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240
JBrowse link
G Mir210 microRNA 210 acts_upstream_of_or_within ISO (PMID:19520079) RGD PMID:19520079 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Ski Ski proto-oncogene involved_in ISO (PMID:14699069) RGD PMID:14699069 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:16720724) RGD PMID:16720724 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:16720724)
GO_REF:0000107
RGD
Ensembl
PMID:16720724 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:16720724) RGD PMID:16720724 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
negative regulation of nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dact2 dishevelled-binding antagonist of beta-catenin 2 involved_in ISO
IBA
(MGI:3809364|PMID:18716284), (MGI:5437437|PMID:17197390)
GO_REF:0000033
RGD
GO_Central
PMID:17197390 PMID:18716284 GO_REF:0000033 MGI:3809364 MGI:5437437 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Lefty1 left right determination factor 1 involved_in ISO (MGI:3042530|PMID:15062104) RGD PMID:15062104 MGI:3042530 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    negative regulation of biological process 5812
      negative regulation of response to stimulus 1888
        negative regulation of signal transduction 1466
          negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 183
            negative regulation of activin receptor signaling pathway 17
              negative regulation of nodal signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of cellular process 12748
          signal transduction 7209
            cell surface receptor signaling pathway 2886
              enzyme-linked receptor protein signaling pathway 1053
                cell surface receptor protein serine/threonine kinase signaling pathway 434
                  transforming growth factor beta receptor superfamily signaling pathway 398
                    activin receptor signaling pathway 52
                      regulation of activin receptor signaling pathway 28
                        negative regulation of activin receptor signaling pathway 17
                          negative regulation of nodal signaling pathway + 3
paths to the root