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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotrophin production
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Accession:GO:0032898 term browser browse the term
Definition:The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.

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negative regulation of nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin, paired basic amino acid cleaving enzyme NOT|involved_in ISO (PMID:10567353) BHF-UCL PMID:10567353 NCBI chrNW_004936483:16,136,099...16,147,945
Ensembl chrNW_004936483:16,136,099...16,144,635 		JBrowse link
negative regulation of neurotrophin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:19524026 RGD:2317915 NCBI chrNW_004936567:1,430,128...1,508,626
Ensembl chrNW_004936567:1,429,817...1,462,532 		JBrowse link
nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:16,136,099...16,147,945
Ensembl chrNW_004936483:16,136,099...16,144,635 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:2,374,357...2,561,322
Ensembl chrNW_004936483:2,374,357...2,561,384 		JBrowse link
positive regulation of neurotrophin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin associated protein 1 involved_in ISO PMID:21357693
PMID:19996106		 UniProt PMID:19996106 PMID:21357693 RGD:10047154 RGD:10047187 NCBI chrNW_004936490:16,645,116...16,652,310
Ensembl chrNW_004936490:16,643,520...16,652,479 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO RGD PMID:23237228 RGD:12832758 NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599 		JBrowse link
regulation of nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npy neuropeptide Y ISO RGD PMID:22860197 RGD:10448933 NCBI chrNW_004936478:1,289,437...1,296,819
Ensembl chrNW_004936478:1,290,505...1,296,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    multicellular organismal process 7386
      neurotrophin production 6
        negative regulation of neurotrophin production + 2
        nerve growth factor production + 3
        positive regulation of neurotrophin production 2
        regulation of neurotrophin production + 5
paths to the root