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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotrophin production
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Accession:GO:0032898 term browser browse the term
Definition:The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.


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negative regulation of nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme NOT|involved_in IDA (PMID:10567353) BHF-UCL PMID:10567353 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564 		JBrowse link
negative regulation of neurotrophin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor involved_in ISO
IEA		 RGD
Ensembl		 PMID:19524026 GO_REF:0000107 RGD:2317915 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IDA (PMID:8615794) BHF-UCL PMID:8615794 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564 		JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 involved_in IDA (PMID:8615794) BHF-UCL PMID:8615794 NCBI chr15:101,303,933...101,489,707
Ensembl chr15:101,289,784...101,525,202 		JBrowse link
positive regulation of neurotrophin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAP1 huntingtin associated protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:41,717,739...41,734,646
Ensembl chr17:41,717,742...41,734,644 		JBrowse link
G SHH sonic hedgehog signaling molecule ISO RGD PMID:23237228 RGD:12832758 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
regulation of nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPY neuropeptide Y ISO RGD PMID:22860197 RGD:10448933 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    multicellular organismal process 8501
      neurotrophin production 6
        negative regulation of neurotrophin production + 2
        nerve growth factor production + 3
        positive regulation of neurotrophin production 2
        regulation of neurotrophin production + 5
paths to the root