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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotrophin production
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Accession:GO:0032898 term browser browse the term
Definition:The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.


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negative regulation of nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) NOT|involved_in ISO (PMID:10567353) RGD PMID:10567353 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
negative regulation of neurotrophin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IMP RGD PMID:19524026 RGD:2317915 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:8615794)
GO_REF:0000107		 RGD
Ensembl		 PMID:8615794 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 involved_in ISO
IEA		 (PMID:8615794)
GO_REF:0000107		 RGD
Ensembl		 PMID:8615794 GO_REF:0000107 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
positive regulation of neurotrophin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 involved_in IMP
IDA		 PMID:19996106
PMID:21357693		 UniProt PMID:19996106 PMID:21357693 RGD:10047154, RGD:10047187 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Shh sonic hedgehog signaling molecule IMP RGD PMID:23237228 RGD:12832758 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
regulation of nerve growth factor production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npy neuropeptide Y IDA RGD PMID:22860197 RGD:10448933 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    multicellular organismal process 9192
      neurotrophin production 6
        negative regulation of neurotrophin production + 2
        nerve growth factor production + 3
        positive regulation of neurotrophin production 2
        regulation of neurotrophin production + 5
paths to the root