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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of natural killer cell differentiation
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Accession:GO:0032823 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of natural killer cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: regulation of NK cell differentiation
 related_synonym: regulation of natural killer cell development



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regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Prdm1 PR/SET domain 1 involved_in ISO
IEA
(PMID:27102484)
GO_REF:0000107
RGD
Ensembl
PMID:27102484 GO_REF:0000107 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:27102484) RGD PMID:27102484 NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:146,278,978...146,285,000
JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 acts_upstream_of_or_within ISO MGI:2670590 (PMID:20709292) RGD PMID:20709292 NCBI chr 1:87,659,863...87,665,048
Ensembl chr 1:78,531,815...78,537,001
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within ISO
IEA
MGI:5297105 (PMID:20709292)
GO_REF:0000107
RGD
Ensembl
PMID:20709292 GO_REF:0000107 NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:11,418,880...11,427,773
JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:180,174,931...180,186,007
Ensembl chr 2:177,477,407...177,490,736
Ensembl chr 2:177,477,407...177,490,736
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:178,500,238...178,669,328
Ensembl chr 2:176,218,519...176,242,251
JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:18840707) RGD PMID:18840707 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO MGI:2158499 (PMID:14607906) RGD PMID:14607906 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:18840707)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18840707 GO_REF:0000024 GO_REF:0000107 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO
IEA
MGI:1931086|MGI:2136897 (PMID:14607906), (PMID:17318811)
GO_REF:0000107
RGD
Ensembl
PMID:14607906 PMID:17318811 GO_REF:0000107 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha acts_upstream_of_or_within ISO
IEA
MGI:1934016 (PMID:14607906)
GO_REF:0000107
RGD
Ensembl
PMID:14607906 GO_REF:0000107 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:66,802,334...66,832,278
JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21957144)
Ensembl
RGD
PMID:21957144 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO
IEA
MGI:1857249 (PMID:9841920)
GO_REF:0000107
RGD
Ensembl
PMID:9841920 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within ISO
IEA
MGI:2181592 (PMID:9841920)
GO_REF:0000107
RGD
Ensembl
PMID:9841920 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Tox thymocyte selection-associated high mobility group box acts_upstream_of_or_within ISO
IEA
MGI:3773716 (PMID:20818394)
GO_REF:0000107
RGD
Ensembl
PMID:20818394 GO_REF:0000107 NCBI chr 5:24,672,487...24,968,754
Ensembl chr 5:19,874,467...20,171,272
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO
IEA
(PMID:22753936)
GO_REF:0000107
RGD
Ensembl
PMID:22753936 GO_REF:0000107 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:22885984) RGD PMID:22885984 NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:146,278,978...146,285,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3132
      leukocyte activation 1084
        lymphocyte activation 878
          lymphocyte differentiation 455
            natural killer cell differentiation 35
              regulation of natural killer cell differentiation 18
                negative regulation of natural killer cell differentiation + 4
                positive regulation of natural killer cell differentiation + 11
                regulation of natural killer cell differentiation involved in immune response + 5
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      cellular developmental process 4838
        cell differentiation 4837
          cell development 3352
            hemopoiesis 1084
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 455
                    regulation of lymphocyte differentiation 217
                      regulation of natural killer cell differentiation 18
                        negative regulation of natural killer cell differentiation + 4
                        positive regulation of natural killer cell differentiation + 11
                        regulation of natural killer cell differentiation involved in immune response + 5
paths to the root