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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of natural killer cell activation
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Accession:GO:0032814 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of natural killer cell activation.
Synonyms:exact_synonym: regulation of NK cell activation


show annotations for term's descendants           Sort by:
regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dcaf15 DDB1 and CUL4 associated factor 15 involved_in ISO
IEA 		(PMID:31452512)
GO_REF:0000107 		RGD
Ensembl		 PMID:31452512 GO_REF:0000107 NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277 		JBrowse link
G Lep leptin involved_in ISO
IEA
ISS 		(PMID:12504075)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:12504075 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO
IEA 		MGI:1922595 (PMID:19151721)
GO_REF:0000107 		RGD
Ensembl		 PMID:19151721 GO_REF:0000107 NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509 		JBrowse link
G Slamf7 SLAM family member 7 acts_upstream_of_or_within ISO MGI:3622649 (PMID:19151721) RGD PMID:19151721 NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105 		JBrowse link
negative regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec12a C-type lectin domain family 12, member A involved_in ISO (PMID:15238421), (PMID:31269448)
(PMID:31269448) 		RGD PMID:15238421 PMID:31269448 NCBI chr 4:164,484,162...164,502,793
Ensembl chr 4:162,798,125...162,816,753 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (PMID:15199160), (PMID:16439675) RGD PMID:15199160 PMID:16439675 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:16439675) RGD PMID:16439675 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:25337993) RGD PMID:25337993 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO
IEA 		(PMID:12516630)
GO_REF:0000107 		RGD
Ensembl		 PMID:12516630 GO_REF:0000107 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712 		JBrowse link
G Rhbdd3 rhomboid domain containing 3 acts_upstream_of_or_within ISO
IEA 		MGI:5516031 (PMID:23610400)
GO_REF:0000107 		RGD
Ensembl		 PMID:23610400 GO_REF:0000107 NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:37264229) RGD PMID:37264229 NCBI chr20:4,872,720...4,876,425 JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 acts_upstream_of_or_within ISO MGI:2670590 (PMID:20709292) RGD PMID:20709292 NCBI chr 1:87,659,863...87,665,048
Ensembl chr 1:78,531,815...78,537,001 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within ISO
IEA 		MGI:5297105 (PMID:20709292)
GO_REF:0000107 		RGD
Ensembl		 PMID:20709292 GO_REF:0000107 NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:11,418,880...11,427,773 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:180,174,931...180,186,007
Ensembl chr 2:177,477,407...177,490,736
Ensembl chr 2:177,477,407...177,490,736 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:178,500,238...178,669,328
Ensembl chr 2:176,218,519...176,242,251 		JBrowse link
positive regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 acts_upstream_of_or_within ISO
IEA 		MGI:1857021 (PMID:7089489)
GO_REF:0000107 		RGD
Ensembl		 PMID:7089489 GO_REF:0000107 NCBI chr 1:79,155,873...79,158,247
Ensembl chr 1:79,155,693...79,158,505 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO
IEA 		MGI:1856982 (PMID:7089489)
GO_REF:0000107 		RGD
Ensembl		 PMID:7089489 GO_REF:0000107 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO MGI:1856712 (PMID:7089489) RGD PMID:7089489 NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA 		(PMID:1674604)
GO_REF:0000107 		RGD
Ensembl		 PMID:1674604 GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:1674604)
GO_REF:0000107 		RGD
Ensembl		 PMID:1674604 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO MGI:1855968 (PMID:7089489) RGD PMID:7089489 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480 		JBrowse link
G Mir130a microRNA 130a involved_in ISO (PMID:31883616) RGD PMID:31883616 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO
IEA 		(PMID:21957144)
GO_REF:0000107 		RGD
Ensembl		 PMID:21957144 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:37264229) RGD PMID:37264229 NCBI chr20:4,872,720...4,876,425 JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3701472 (PMID:21059856) RGD PMID:21059856 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO 		GO_REF:0000033
(PMID:9647200) 		GO_Central
RGD		 PMID:9647200 GO_REF:0000033 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:18840707) RGD PMID:18840707 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO MGI:2158499 (PMID:14607906) RGD PMID:14607906 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:18840707)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18840707 GO_REF:0000024 GO_REF:0000107 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO
IEA 		MGI:1931086|MGI:2136897 (PMID:14607906), (PMID:17318811)
GO_REF:0000107 		RGD
Ensembl		 PMID:14607906 PMID:17318811 GO_REF:0000107 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha acts_upstream_of_or_within ISO
IEA 		MGI:1934016 (PMID:14607906)
GO_REF:0000107 		RGD
Ensembl		 PMID:14607906 GO_REF:0000107 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:66,802,334...66,832,278 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21957144) 		Ensembl
RGD		 PMID:21957144 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO
IEA 		MGI:1857249 (PMID:9841920)
GO_REF:0000107 		RGD
Ensembl		 PMID:9841920 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within ISO
IEA 		MGI:2181592 (PMID:9841920)
GO_REF:0000107 		RGD
Ensembl		 PMID:9841920 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Tox thymocyte selection-associated high mobility group box acts_upstream_of_or_within ISO
IEA 		MGI:3773716 (PMID:20818394)
GO_REF:0000107 		RGD
Ensembl		 PMID:20818394 GO_REF:0000107 NCBI chr 5:24,672,487...24,968,754
Ensembl chr 5:19,874,467...20,171,272 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO
IEA 		(PMID:22753936)
GO_REF:0000107 		RGD
Ensembl		 PMID:22753936 GO_REF:0000107 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:95,096,387...95,118,996 		JBrowse link
positive regulation of natural killer cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:15905190) RGD PMID:15905190 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:9916693) RGD PMID:9916693 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand IDA RGD PMID:16528542 RGD:11049499 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO
IEA 		(PMID:14607906)
GO_REF:0000107 		RGD
Ensembl		 PMID:14607906 GO_REF:0000107 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,872,720...4,876,425 JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within ISO
IEA 		MGI:2181592 (PMID:9841920)
GO_REF:0000107 		RGD
Ensembl		 PMID:9841920 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Prdm1 PR/SET domain 1 involved_in ISO
IEA 		(PMID:27102484)
GO_REF:0000107 		RGD
Ensembl		 PMID:27102484 GO_REF:0000107 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:27102484) RGD PMID:27102484 NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:146,278,978...146,285,000 		JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:22885984) RGD PMID:22885984 NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:146,278,978...146,285,000 		JBrowse link
regulation of natural killer cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lep leptin involved_in ISO
IEA
ISS 		(PMID:12504075)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:12504075 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO
ISS 		(PMID:20522204)
GO_REF:0000024 		RGD
BHF-UCL		 PMID:20522204 GO_REF:0000024 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3132
      regulation of immune system process 1746
        regulation of leukocyte activation 609
          regulation of lymphocyte activation 525
            regulation of natural killer cell activation 47
              negative regulation of natural killer cell activation + 13
              positive regulation of natural killer cell activation + 28
              regulation of natural killer cell differentiation + 18
              regulation of natural killer cell proliferation + 13
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of cellular process 13032
          regulation of cell activation 667
            regulation of leukocyte activation 609
              regulation of lymphocyte activation 525
                regulation of natural killer cell activation 47
                  negative regulation of natural killer cell activation + 13
                  positive regulation of natural killer cell activation + 28
                  regulation of natural killer cell differentiation + 18
                  regulation of natural killer cell proliferation + 13
paths to the root