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Term:DNA ligase IV complex
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Accession:GO:0032807 term browser browse the term
Definition:A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.
Synonyms:exact_synonym: DNA ligase IV-XRCC4 complex

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DNA ligase IV complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig4 DNA ligase 4 ISO
RGD PMID:9809069, PMID:21873635 RGD:13792537 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
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G Nhej1 nonhomologous end-joining factor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:82,230,230...82,327,923
Ensembl chr 9:82,230,232...82,327,534
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO
RGD PMID:9242410, PMID:21873635 RGD:13792537 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      DNA ligase IV complex 3
Path 2
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  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        membrane-bounded organelle 11449
          intracellular membrane-bounded organelle 10704
            nucleus 7183
              DNA ligase IV complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.