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ONTOLOGY REPORT - ANNOTATIONS


Term:carboxy-terminal domain protein kinase complex
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Accession:GO:0032806 term browser browse the term
Definition:A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.
Synonyms:exact_synonym: CTDK complex


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core TFIIH complex portion of holo TFIIH complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2h2 general transcription factor IIH subunit 2 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:30,494,718...30,522,716
Ensembl chr 2:30,494,825...30,522,727
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 ISO
ISS
(PMID:27193682)
GO_REF:0000024
RGD
UniProt
PMID:27193682 GO_REF:0000024 NCBI chr12:37,427,556...37,444,027
Ensembl chr12:37,427,546...37,444,282
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr20:3,582,688...3,588,373
Ensembl chr20:3,582,742...3,588,375
JBrowse link
cyclin-dependent protein kinase activating kinase holoenzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H ISO (PMID:23393140), (PMID:8692841), (PMID:8692842) RGD PMID:8692841 PMID:8692842 PMID:23393140 NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
JBrowse link
G Cdk7 cyclin-dependent kinase 7 IEA
ISO
GO_REF:0000107
(PMID:23393140), (PMID:8692841)
Ensembl
RGD
PMID:8692841 PMID:23393140 GO_REF:0000107 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase ISO (PMID:11445587), (PMID:8692841) RGD PMID:8692841 PMID:11445587 NCBI chr 6:95,995,341...96,153,331
Ensembl chr 6:96,007,805...96,153,330
JBrowse link
cyclin/CDK positive transcription elongation factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 ISO (MGI:5500979|PMID:23752591) RGD PMID:23752591 MGI:5500979 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Ccnk cyclin K IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557
JBrowse link
G Ccnt1 cyclin T1 ISO
IBA
(PMID:15905409), (PMID:9499409)
PMID:21873635
RGD PMID:9499409 PMID:15905409, PMID:21873635 RGD:13792537 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Ccnt2 cyclin T2 ISO
IBA
(PMID:9499409)
PMID:21873635
RGD PMID:9499409, PMID:21873635 RGD:13792537 NCBI chr13:44,475,959...44,516,892
Ensembl chr13:44,475,970...44,515,739
JBrowse link
G Cdk12 cyclin-dependent kinase 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,157,186...86,210,657
Ensembl chr10:86,157,608...86,222,707
JBrowse link
G Cdk13 cyclin-dependent kinase 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Cdk9 cyclin-dependent kinase 9 ISS
ISO
GO_REF:0000024
(MGI:5500979|PMID:23752591)
(PMID:15905409), (PMID:9499409)
UniProt
RGD
PMID:9499409 PMID:15905409 PMID:23752591 GO_REF:0000024 MGI:5500979 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G LOC103692976 cyclin-T1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:140,149,991...140,172,615
Ensembl chr 7:140,154,490...140,172,448
JBrowse link
G Rb1 RB transcriptional corepressor 1 colocalizes_with IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:12037672)
Ensembl
UniProt
RGD
PMID:12037672 GO_REF:0000024 GO_REF:0000107 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Snw1 SNW domain containing 1 colocalizes_with ISO (PMID:15905409) RGD PMID:15905409 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
P-TEFb complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt1 cyclin T1 ISO (PMID:18483487), (PMID:28431135) RGD PMID:18483487 PMID:28431135 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Cdk9 cyclin-dependent kinase 9 ISO (PMID:18483487) RGD PMID:18483487 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
transcription factor TFIIH holo complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063323.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:28,557,633...28,557,848 JBrowse link
G Ccnh cyclin H ISO
IBA
ISS
(PMID:9852112)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:9852112, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
JBrowse link
G Cdk7 cyclin-dependent kinase 7 IDA
ISS
ISO
GO_REF:0000024
(PMID:9852112)
UniProt
RGD
PMID:9852112, PMID:7553866 GO_REF:0000024, RGD:9590319 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO (PMID:9852112) RGD PMID:9852112 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit ISS
ISO
IBA
GO_REF:0000024
(PMID:9852112)
PMID:21873635
UniProt
RGD
PMID:9852112, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 IDA RGD PMID:7553866 RGD:9590319 NCBI chr15:57,942,057...58,068,892
Ensembl chr15:57,942,059...58,068,892
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 IDA
IBA
ISO
PMID:21873635
(PMID:9852112)
RGD PMID:9852112, PMID:7553866, PMID:21873635 RGD:9590319, RGD:13792537 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 ISS
IBA
GO_REF:0000024
PMID:21873635
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:30,494,718...30,522,716
Ensembl chr 2:30,494,825...30,522,727
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 ISO
IBA
ISS
(PMID:9852112)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:9852112, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:37,427,556...37,444,027
Ensembl chr12:37,427,546...37,444,282
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112, PMID:21873635 RGD:13792537 NCBI chr20:3,582,688...3,588,373
Ensembl chr20:3,582,742...3,588,375
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:46,978,345...46,985,032
Ensembl chr 1:46,978,458...46,985,032
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112, PMID:21873635 RGD:13792537 NCBI chr 6:95,995,341...96,153,331
Ensembl chr 6:96,007,805...96,153,330
JBrowse link
transcription factor TFIIK complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H IBA
ISO
PMID:21873635
(PMID:8692841)
RGD PMID:8692841, PMID:21873635 RGD:13792537 NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
JBrowse link
G Cdk7 cyclin-dependent kinase 7 IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:8692841)
Ensembl
RGD
PMID:8692841, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase ISO (PMID:8692841) RGD PMID:8692841 NCBI chr 6:95,995,341...96,153,331
Ensembl chr 6:96,007,805...96,153,330
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20615
    protein-containing complex 6107
      nuclear protein-containing complex 1237
        carboxy-terminal domain protein kinase complex 22
          cyclin-dependent protein kinase activating kinase holoenzyme complex 3
          cyclin/CDK positive transcription elongation factor complex + 10
          transcription factor TFIIH holo complex + 12
Path 2
Term Annotations click to browse term
  cellular_component 20615
    cellular anatomical entity 20304
      organelle 13278
        membrane-bounded organelle 11263
          intracellular membrane-bounded organelle 10518
            nucleus 6987
              nuclear protein-containing complex 1237
                carboxy-terminal domain protein kinase complex 22
                  cyclin-dependent protein kinase activating kinase holoenzyme complex 3
                  cyclin/CDK positive transcription elongation factor complex + 10
                  transcription factor TFIIH holo complex + 12
paths to the root