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ONTOLOGY REPORT - ANNOTATIONS


Term:carboxy-terminal domain protein kinase complex
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Accession:GO:0032806 term browser browse the term
Definition:A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.
Synonyms:exact_synonym: CTDK complex



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core TFIIH complex portion of holo TFIIH complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2h2 general transcription factor IIH subunit 2 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 part_of ISO
ISS
(PMID:27193682)
GO_REF:0000024
RGD
UniProt
PMID:27193682 GO_REF:0000024 NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 part_of ISO (PMID:27193682) RGD PMID:27193682 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
JBrowse link
cyclin-dependent protein kinase activating kinase holoenzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H part_of ISO (PMID:23393140), (PMID:8692841), (PMID:8692842) RGD PMID:8692841 PMID:8692842 PMID:23393140 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of ISO
IEA
(PMID:23393140), (PMID:8692841)
GO_REF:0000107
RGD
Ensembl
PMID:8692841 PMID:23393140 GO_REF:0000107 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO (PMID:11445587), (PMID:8692841) RGD PMID:8692841 PMID:11445587 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
JBrowse link
cyclin/CDK positive transcription elongation factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 part_of ISO (MGI:5500979|PMID:23752591) RGD PMID:23752591 MGI:5500979 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Ccnk cyclin K part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
JBrowse link
G Ccnt1 cyclin T1 part_of
located_in
ISO
IBA
(PMID:15905409), (PMID:9499409)
(PMID:18566585)
PMID:21873635
RGD PMID:9499409 PMID:15905409 PMID:18566585 PMID:21873635 RGD:13792537 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Ccnt2 cyclin T2 part_of
located_in
ISO
IBA
(PMID:9499409)
PMID:21873635
RGD PMID:9499409 PMID:21873635 RGD:13792537 NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019
JBrowse link
G Cdk12 cyclin-dependent kinase 12 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
JBrowse link
G Cdk13 cyclin-dependent kinase 13 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
JBrowse link
G Cdk9 cyclin-dependent kinase 9 part_of
located_in
ISO
ISS
(PMID:15905409), (PMID:9499409)
(PMID:18566585), (PMID:9499409)
(MGI:5500979|PMID:23752591)
GO_REF:0000024
RGD
UniProt
PMID:9499409 PMID:15905409 PMID:18566585 PMID:23752591 GO_REF:0000024 MGI:5500979 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Rb1 RB transcriptional corepressor 1 colocalizes_with
part_of
ISO
IEA
ISS
(PMID:12037672)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12037672 GO_REF:0000024 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Snw1 SNW domain containing 1 colocalizes_with
part_of
ISO
IEA
(PMID:15905409)
GO_REF:0000107
RGD
Ensembl
PMID:15905409 GO_REF:0000107 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
P-TEFb complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt1 cyclin T1 part_of ISO (PMID:18483487), (PMID:28431135) RGD PMID:18483487 PMID:28431135 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Cdk9 cyclin-dependent kinase 9 part_of ISO (PMID:18483487) RGD PMID:18483487 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
transcription factor TFIIH holo complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063323.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:27,111,331...27,111,546 JBrowse link
G Ccnh cyclin H part_of ISS
ISO
GO_REF:0000024
(PMID:9852112)
UniProt
RGD
PMID:9852112 GO_REF:0000024 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of IDA
ISO
ISS
(PMID:9852112)
GO_REF:0000024
RGD
UniProt
PMID:9852112 PMID:7553866 GO_REF:0000024, RGD:9590319 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit part_of ISO (PMID:9852112) RGD PMID:9852112 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit part_of IBA
ISO
ISS
PMID:21873635
(PMID:9852112)
GO_REF:0000024
RGD
UniProt
PMID:9852112 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 IDA RGD PMID:7553866 RGD:9590319 NCBI chr15:51,206,027...51,327,166
Ensembl chr15:51,206,031...51,327,253
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 part_of IDA
ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112 PMID:7553866 PMID:21873635 RGD:9590319, RGD:13792537 NCBI chr 1:97,321,401...97,349,455
Ensembl chr 1:97,321,394...97,349,455
JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 part_of IBA
ISS
PMID:21873635
GO_REF:0000024
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 part_of ISO
ISS
IBA
(PMID:9852112)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:9852112 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 part_of ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112 PMID:21873635 RGD:13792537 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO
IBA
(PMID:9852112)
PMID:21873635
RGD PMID:9852112 PMID:21873635 RGD:13792537 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
JBrowse link
transcription factor TFIIK complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H part_of IBA
ISO
PMID:21873635
(PMID:8692841)
RGD PMID:8692841 PMID:21873635 RGD:13792537 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:8692841)
Ensembl
RGD
PMID:8692841 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO (PMID:8692841) RGD PMID:8692841 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    protein-containing complex 6165
      nuclear protein-containing complex 1289
        carboxy-terminal domain protein kinase complex 21
          cyclin-dependent protein kinase activating kinase holoenzyme complex 3
          cyclin/CDK positive transcription elongation factor complex + 9
          transcription factor TFIIH holo complex + 12
Path 2
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      organelle 13088
        membrane-bounded organelle 11697
          intracellular membrane-bounded organelle 11218
            nucleus 7051
              nuclear protein-containing complex 1289
                carboxy-terminal domain protein kinase complex 21
                  cyclin-dependent protein kinase activating kinase holoenzyme complex 3
                  cyclin/CDK positive transcription elongation factor complex + 9
                  transcription factor TFIIH holo complex + 12
paths to the root