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ONTOLOGY REPORT - ANNOTATIONS


Term:low-density lipoprotein particle receptor catabolic process
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Accession:GO:0032802 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: LDL receptor breakdown;   LDL receptor catabolic process;   LDL receptor degradation;   low-density lipoprotein receptor breakdown;   low-density lipoprotein receptor catabolic process;   low-density lipoprotein receptor catabolism;   low-density lipoprotein receptor degradation
 related_synonym: LDL receptor catabolism


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low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1600115
RGD:1624291
RGD:629554
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:1624291
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291
RGD:1600115
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:1600115
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mylip myosin regulatory light chain interacting protein JBrowse link 17 19,682,040 19,703,681 RGD:1624291
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      catabolic process 2516
        cellular catabolic process 2149
          receptor catabolic process 29
            low-density lipoprotein particle receptor catabolic process 6
              negative regulation of low-density lipoprotein particle receptor catabolic process 2
              positive regulation of low-density lipoprotein particle receptor catabolic process 3
              regulation of low-density lipoprotein particle receptor catabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      catabolic process 2516
        organic substance catabolic process 2072
          macromolecule catabolic process 1322
            protein catabolic process 977
              cellular protein catabolic process 814
                low-density lipoprotein particle receptor catabolic process 6
                  negative regulation of low-density lipoprotein particle receptor catabolic process 2
                  positive regulation of low-density lipoprotein particle receptor catabolic process 3
                  regulation of low-density lipoprotein particle receptor catabolic process + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.