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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation


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receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link NW_004936490 17,518,100 17,531,126 RGD:9068941
G Capn1 calpain 1 JBrowse link NW_004936599 4,178,963 4,201,037 RGD:9068941
G Cdk5 cyclin dependent kinase 5 JBrowse link NW_004936527 6,478,934 6,483,848 RGD:9068941
G Kif16b kinesin family member 16B JBrowse link NW_004936485 3,443,878 3,728,613 RGD:9068941
G Lgmn legumain JBrowse link NW_004936733 772,764 792,792 RGD:9068941
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link NW_004936471 17,254,777 17,374,725 RGD:9068941
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 JBrowse link NW_004936529 4,162,276 4,232,471 RGD:9068941
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link NW_004936732 2,066,848 2,097,947 RGD:9068941
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link NW_004936750 1,381,864 1,406,736 RGD:9068941
G Snx25 sorting nexin 25 JBrowse link NW_004936554 3,982,755 4,093,143 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Uvrag UV radiation resistance associated JBrowse link NW_004936498 4,555,325 4,869,099 RGD:9068941
G protein-coupled receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn2 beclin 2 JBrowse link NW_004936526 8,532,991 8,534,271 RGD:9068941
G Gprasp1 G protein-coupled receptor associated sorting protein 1 JBrowse link NW_004936813 1,208,018 1,213,224 RGD:9068941
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link NW_004936522 6,271,339 6,300,202 RGD:9068941
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link NW_004936471 21,274,112 21,329,286 RGD:9068941
G Furin furin, paired basic amino acid cleaving enzyme JBrowse link NW_004936483 16,136,099 16,147,945 RGD:9068941
negative regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtmr2 myotubularin related protein 2 JBrowse link NW_004936700 1,790,592 1,873,019 RGD:9068941
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link NW_004936669 922,978 941,996 RGD:9068941
G Apoe apolipoprotein E JBrowse link NW_004936706 1,512,438 1,516,805 RGD:9068941
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link NW_004936522 6,271,339 6,300,202 RGD:9068941
positive regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtx3l deltex E3 ubiquitin ligase 3L JBrowse link NW_004936536 8,844,778 8,853,442 RGD:9068941
G Git1 GIT ArfGAP 1 JBrowse link NW_004936538 5,684,660 5,694,779 RGD:9068941
G Hamp hepcidin antimicrobial peptide JBrowse link NW_004936570 1,009,344 1,010,654 RGD:9068941
G Itch itchy E3 ubiquitin protein ligase JBrowse link NW_004936561 6,140,236 6,265,734 RGD:9068941
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 JBrowse link NW_004936514 4,065,455 4,083,847 RGD:9068941
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mylip myosin regulatory light chain interacting protein JBrowse link NW_004936552 2,325,161 2,341,356 RGD:9068941
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link NW_004936522 6,271,339 6,300,202 RGD:9068941
Wnt receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf43 ring finger protein 43 JBrowse link NW_004936490 4,660,904 4,742,669 RGD:9068941
G Znrf3 zinc and ring finger 3 JBrowse link NW_004936657 3,064,199 3,119,903 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11933
    metabolic process 7631
      catabolic process 1620
        cellular catabolic process 1421
          receptor catabolic process 28
            G protein-coupled receptor catabolic process 2
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 6
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 8
            regulation of receptor catabolic process + 12
Path 2
Term Annotations click to browse term
  biological_process 11933
    metabolic process 7631
      organic substance metabolic process 7329
        macromolecule metabolic process 6362
          cellular macromolecule metabolic process 5494
            receptor metabolic process 204
              receptor catabolic process 28
                G protein-coupled receptor catabolic process 2
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 6
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 8
                regulation of receptor catabolic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.