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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation


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receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:1624291
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:1624291
RGD:1600115
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:1624291
G Kif16b kinesin family member 16B JBrowse link 3 136,596,621 136,936,809 RGD:1624291
G Lgmn legumain JBrowse link 6 126,282,246 126,308,207 RGD:1600115
RGD:1624291
G Mvb12a multivesicular body subunit 12A JBrowse link 16 19,973,611 19,978,479 RGD:13792537
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link 8 79,323,408 79,408,842 RGD:1600115
RGD:13792537
RGD:1624291
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 JBrowse link 8 114,300,248 114,350,686 RGD:1624291
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 JBrowse link 2 250,709,812 250,744,216 RGD:1624291
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 12 11,433,815 11,526,465 RGD:1624291
G Snx25 sorting nexin 25 JBrowse link 16 49,328,958 49,432,415 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Uvrag UV radiation resistance associated JBrowse link 1 163,844,804 164,101,568 RGD:1624291
G protein-coupled receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn2 beclin 2 JBrowse link 13 93,971,720 93,974,467 RGD:1624291
G Gprasp1 G protein-coupled receptor associated sorting protein 1 JBrowse link X 106,306,795 106,313,904 RGD:1624291
RGD:1600115
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1600115
RGD:1624291
RGD:629554
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:1624291
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291
RGD:1600115
negative regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:1600115
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
positive regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtx3l deltex E3 ubiquitin ligase 3L JBrowse link 11
11
67,758,093
67,768,542
67,767,623
67,772,428
RGD:1624291
G Git1 GIT ArfGAP 1 JBrowse link 10 62,656,000 62,664,467 RGD:13513208
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Itch itchy E3 ubiquitin protein ligase JBrowse link 3 150,660,665 150,752,016 RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mylip myosin regulatory light chain interacting protein JBrowse link 17 19,682,040 19,703,681 RGD:1624291
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
Wnt receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf43 ring finger protein 43 JBrowse link 10 74,956,411 75,028,951 RGD:1624291
RGD:13792537
G Znrf3 zinc and ring finger 3 JBrowse link 14 85,527,099 85,586,294 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19676
    metabolic process 11952
      catabolic process 2500
        cellular catabolic process 2140
          receptor catabolic process 29
            G protein-coupled receptor catabolic process 2
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 6
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 8
            regulation of receptor catabolic process + 12
Path 2
Term Annotations click to browse term
  biological_process 19676
    metabolic process 11952
      organic substance metabolic process 11358
        macromolecule metabolic process 9814
          cellular macromolecule metabolic process 8270
            receptor metabolic process 218
              receptor catabolic process 29
                G protein-coupled receptor catabolic process 2
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 6
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 8
                regulation of receptor catabolic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.