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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation


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receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BECN1 beclin 1 JBrowse link 12 20,041,914 20,054,249 RGD:14298760
G CAPN1 calpain 1 JBrowse link 2 6,997,513 7,024,410 RGD:14298760
G CDK5 cyclin dependent kinase 5 JBrowse link 18 6,166,914 6,171,157 RGD:14298760
G KIF16B kinesin family member 16B JBrowse link 17 24,882,139 25,188,990 RGD:9068941
G LGMN legumain JBrowse link 7 114,176,217 114,210,096 RGD:14298760
G MVB12A multivesicular body subunit 12A JBrowse link 2 60,271,020 60,275,972 RGD:14298760
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 1 115,941,945 116,069,884 RGD:14298760
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 JBrowse link 13 1,730,988 1,815,555 RGD:14298760
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 4 129,361,596 129,395,790 RGD:9068941
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 3 6,037,732 6,142,569 RGD:9068941
G SNX25 sorting nexin 25 JBrowse link 15 46,306,967 46,388,404 RGD:14298760
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:14298760
G UVRAG UV radiation resistance associated JBrowse link 9 10,088,779 10,370,857 RGD:14298760
G protein-coupled receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BECN2 beclin 2 JBrowse link 10 15,388,712 15,390,250 RGD:14298760
G GPRASP1 G protein-coupled receptor associated sorting protein 1 JBrowse link X 83,765,210 83,810,090 RGD:9068941
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCSK9 proprotein convertase subtilisin/kexin type 9 JBrowse link 6 157,388,370 157,409,620 RGD:14298760
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA2 annexin A2 JBrowse link 1 111,588,721 111,635,064 RGD:14298760
G FURIN furin, paired basic amino acid cleaving enzyme JBrowse link 7 53,455,634 53,472,791 RGD:14298760
negative regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTMR2 myotubularin related protein 2 JBrowse link 9 27,864,335 27,974,448 RGD:9068941
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA2 ATP binding cassette subfamily A member 2 RGD:9068941
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:14298760
G PCSK9 proprotein convertase subtilisin/kexin type 9 JBrowse link 6 157,388,370 157,409,620 RGD:14298760
positive regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DTX3L deltex E3 ubiquitin ligase 3L JBrowse link 13 137,950,266 137,961,381 RGD:14298760
G GIT1 GIT ArfGAP 1 JBrowse link 12 45,768,172 45,783,652 RGD:9068941
G HAMP hepcidin antimicrobial peptide JBrowse link 6 44,785,863 44,787,303 RGD:9068941
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 17 37,810,113 37,918,963 RGD:9068941
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 17 52,017,100 52,086,747 RGD:14298760
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYLIP myosin regulatory light chain interacting protein JBrowse link 7 12,117,240 12,137,934 RGD:14298760
G PCSK9 proprotein convertase subtilisin/kexin type 9 JBrowse link 6 157,388,370 157,409,620 RGD:9068941
Wnt receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF43 ring finger protein 43 JBrowse link 12 34,631,574 34,695,021 RGD:14298760
G ZNRF3 zinc and ring finger 3 JBrowse link 14 46,092,000 46,241,327 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      catabolic process 2177
        cellular catabolic process 1889
          receptor catabolic process 29
            G protein-coupled receptor catabolic process 2
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 6
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 8
            regulation of receptor catabolic process + 12
Path 2
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      organic substance metabolic process 9900
        macromolecule metabolic process 8603
          cellular macromolecule metabolic process 7296
            receptor metabolic process 219
              receptor catabolic process 29
                G protein-coupled receptor catabolic process 2
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 6
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 8
                regulation of receptor catabolic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.