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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation


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receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1, autophagy related JBrowse link 11 101,288,258 101,302,286 RGD:2290270
G Capn1 calpain 1 JBrowse link 19 5,988,545 6,015,825 RGD:2290270
G Cdk5 cyclin-dependent kinase 5 JBrowse link 5 24,407,597 24,423,587 RGD:2290270
G Kif16b kinesin family member 16B JBrowse link 2 142,618,340 142,901,609 RGD:2290270
G Lgmn legumain JBrowse link 12 102,394,082 102,439,728 RGD:2290270
G Mvb12a multivesicular body subunit 12A JBrowse link 8 71,542,907 71,548,026 RGD:2290270
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 JBrowse link 9 72,662,331 72,749,851 RGD:2290270
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 JBrowse link 9 105,642,995 105,687,655 RGD:2290270
G Sh3glb1 SH3-domain GRB2-like B1 (endophilin) JBrowse link 3 144,683,665 144,720,408 RGD:2290270
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 5 144,876,495 144,965,899 RGD:2290270
G Snx25 sorting nexin 25 JBrowse link 8 46,033,261 46,152,441 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Uvrag UV radiation resistance associated gene JBrowse link 7 98,886,742 99,141,167 RGD:2290270
G protein-coupled receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn2 beclin 2 JBrowse link 1 175,920,329 175,922,225 RGD:2290270
G Gprasp1 G protein-coupled receptor associated sorting protein 1 JBrowse link X 135,742,692 135,803,468 RGD:2290270
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 4 106,442,334 106,464,325 RGD:2290270
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 9 69,453,683 69,491,792 RGD:2290270
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 7 80,389,194 80,405,441 RGD:2290270
negative regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtmr2 myotubularin related protein 2 JBrowse link 9 13,747,260 13,808,896 RGD:2290270
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 JBrowse link 2 25,428,599 25,448,544 RGD:2290270
G Apoe apolipoprotein E JBrowse link 7 19,696,244 19,701,310 RGD:2290270
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 4 106,442,334 106,464,325 RGD:2290270
positive regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtx3l deltex 3-like, E3 ubiquitin ligase JBrowse link 16 35,926,515 35,939,027 RGD:2290270
G Git1 GIT ArfGAP 1 JBrowse link 11 77,493,288 77,507,774 RGD:2290270
G Hamp hepcidin antimicrobial peptide JBrowse link 7 30,942,368 30,944,029 RGD:9068941
G Itch itchy, E3 ubiquitin protein ligase JBrowse link 2 155,133,481 155,226,855 RGD:2290270
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 2 167,930,750 167,979,385 RGD:2290270
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mylip myosin regulatory light chain interacting protein JBrowse link 13 45,389,742 45,411,940 RGD:2290270
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 4 106,442,334 106,464,325 RGD:2290270
Wnt receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf43 ring finger protein 43 JBrowse link 11 87,663,087 87,735,539 RGD:2290270
G Znrf3 zinc and ring finger 3 JBrowse link 11 5,276,329 5,444,847 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23159
    metabolic process 10977
      catabolic process 2383
        cellular catabolic process 2057
          receptor catabolic process 29
            G protein-coupled receptor catabolic process 2
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 6
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 8
            regulation of receptor catabolic process + 12
Path 2
Term Annotations click to browse term
  biological_process 23159
    metabolic process 10977
      organic substance metabolic process 10447
        macromolecule metabolic process 8970
          cellular macromolecule metabolic process 7432
            receptor metabolic process 218
              receptor catabolic process 29
                G protein-coupled receptor catabolic process 2
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 6
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 8
                regulation of receptor catabolic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.