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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation


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receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BECN1 beclin 1 JBrowse link 17 42,810,132 42,824,316 RGD:2290271
G CAPN1 calpain 1 JBrowse link 11 65,181,373 65,212,006 RGD:2290271
G CDK5 cyclin dependent kinase 5 JBrowse link 7 151,053,815 151,057,897 RGD:2290271
G KIF16B kinesin family member 16B JBrowse link 20 16,272,104 16,573,457 RGD:2290271
G LGMN legumain JBrowse link 14 92,703,809 92,748,627 RGD:2290271
G MVB12A multivesicular body subunit 12A JBrowse link 19 17,405,741 17,425,332 RGD:2290271
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 15 55,826,917 55,993,612 RGD:2290271
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 JBrowse link 3 130,678,934 130,746,829 RGD:2290271
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link 1 86,704,570 86,748,184 RGD:2290271
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 7 99,027,435 99,144,118 RGD:2290271
G SNX25 sorting nexin 25 JBrowse link 4 185,204,237 185,368,020 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:2290271
G UVRAG UV radiation resistance associated JBrowse link 11 75,815,189 76,144,232 RGD:2290271
G protein-coupled receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BECN2 beclin 2 JBrowse link 1 241,957,767 241,959,062 RGD:2290271
G GPRASP1 G protein-coupled receptor associated sorting protein 1 JBrowse link X 102,651,366 102,659,083 RGD:2290271
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AP2A1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 19 49,767,001 49,807,114 RGD:2290271
G AP2A2 adaptor related protein complex 2 subunit alpha 2 JBrowse link 11 925,809 1,012,245 RGD:2290271
G AP2B1 adaptor related protein complex 2 subunit beta 1 JBrowse link 17 35,587,265 35,726,413 RGD:2290271
G AP2M1 adaptor related protein complex 2 subunit mu 1 JBrowse link 3 184,174,846 184,184,091 RGD:2290271
G AP2S1 adaptor related protein complex 2 subunit sigma 1 JBrowse link 19 46,838,136 46,850,846 RGD:2290271
G CLTA clathrin light chain A JBrowse link 9 36,190,855 36,212,062 RGD:2290271
G CLTC clathrin heavy chain JBrowse link 17 59,619,689 59,696,956 RGD:2290271
G MYLIP myosin regulatory light chain interacting protein JBrowse link 6 16,129,086 16,151,015 RGD:2290271
G PCSK9 proprotein convertase subtilisin/kexin type 9 JBrowse link 1 55,039,548 55,064,853 RGD:2290271
G VLDLR very low density lipoprotein receptor JBrowse link 9 2,621,786 2,660,056 RGD:2290271
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA2 annexin A2 JBrowse link 15 60,347,151 60,398,025 RGD:2290271
G FURIN furin, paired basic amino acid cleaving enzyme JBrowse link 15 90,868,588 90,883,457 RGD:2290271
negative regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTMR2 myotubularin related protein 2 JBrowse link 11 95,832,880 95,924,110 RGD:2290271
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA2 ATP binding cassette subfamily A member 2 JBrowse link 9 137,007,234 137,028,922 RGD:2290271
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:2290271
G PCSK9 proprotein convertase subtilisin/kexin type 9 JBrowse link 1 55,039,548 55,064,853 RGD:2290271
positive regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DTX3L deltex E3 ubiquitin ligase 3L JBrowse link 3 122,564,338 122,575,203 RGD:2290271
G GIT1 GIT ArfGAP 1 JBrowse link 17 29,573,475 29,589,648 RGD:9068941
G HAMP hepcidin antimicrobial peptide JBrowse link 19 35,282,528 35,285,143 RGD:2290271
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 20 34,363,273 34,511,773 RGD:2290271
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 50,510,321 50,585,241 RGD:2290271
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYLIP myosin regulatory light chain interacting protein JBrowse link 6 16,129,086 16,151,015 RGD:2290271
G PCSK9 proprotein convertase subtilisin/kexin type 9 JBrowse link 1 55,039,548 55,064,853 RGD:9068941
Wnt receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF43 ring finger protein 43 JBrowse link 17 58,352,500 58,418,894 RGD:2290271
G ZNRF3 zinc and ring finger 3 JBrowse link 22 28,800,657 29,057,488 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18534
    metabolic process 12192
      catabolic process 2831
        cellular catabolic process 2444
          receptor catabolic process 37
            G protein-coupled receptor catabolic process 2
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 14
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 8
            regulation of receptor catabolic process + 12
Path 2
Term Annotations click to browse term
  biological_process 18534
    metabolic process 12192
      organic substance metabolic process 11628
        macromolecule metabolic process 10094
          cellular macromolecule metabolic process 8671
            receptor metabolic process 228
              receptor catabolic process 37
                G protein-coupled receptor catabolic process 2
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 14
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 8
                regulation of receptor catabolic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.