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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation


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receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link NW_004955451 16,616,595 16,625,731 RGD:9068941
G Capn1 calpain 1 JBrowse link NW_004955422 20,006,448 20,026,984 RGD:9068941
G Cdk5 cyclin dependent kinase 5 JBrowse link NW_004955491 5,491,744 5,497,280 RGD:9068941
G Kif16b kinesin family member 16B JBrowse link NW_004955415 25,449,734 25,740,697 RGD:9068941
G Lgmn legumain JBrowse link NW_004955438 14,905,856 14,938,722 RGD:9068941
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link NW_004955409 183,645 281,252 RGD:9068941
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 JBrowse link NW_004955501 7,604,934 7,681,947 RGD:9068941
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 JBrowse link NW_004955423 7,393,186 7,414,199 RGD:9068941
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link NW_004955460 14,774,545 14,860,783 RGD:9068941
G Snx25 sorting nexin 25 JBrowse link NW_004955403 23,678,301 23,787,256 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Uvrag UV radiation resistance associated JBrowse link NW_004955414 15,733,116 16,043,555 RGD:9068941
G protein-coupled receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gprasp1 G protein-coupled receptor associated sorting protein 1 JBrowse link NW_004955548 132,373 137,817 RGD:9068941
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link NW_004955464 4,424,583 4,439,805 RGD:9068941
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link NW_004955450 14,545,586 14,574,161 RGD:9068941
G Furin furin, paired basic amino acid cleaving enzyme JBrowse link NW_004955416 14,915,031 14,947,634 RGD:9068941
negative regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtmr2 myotubularin related protein 2 JBrowse link NW_004955412 693,743 764,377 RGD:9068941
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link NW_004955513 5,035,879 5,051,140 RGD:9068941
G Apoe apolipoprotein E JBrowse link NW_004955555 1,998,170 2,002,003 RGD:9068941
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link NW_004955464 4,424,583 4,439,805 RGD:9068941
positive regulation of receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtx3l deltex E3 ubiquitin ligase 3L JBrowse link NW_004955427 21,806,170 21,812,701 RGD:9068941
G Git1 GIT ArfGAP 1 JBrowse link NW_004955481 3,671,728 3,681,279 RGD:9068941
G Hamp hepcidin antimicrobial peptide JBrowse link NW_004955468 4,576,080 4,577,591 RGD:9068941
G Itch itchy E3 ubiquitin protein ligase JBrowse link NW_004955422 26,810,829 26,918,517 RGD:9068941
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 JBrowse link NW_004955445 7,754,313 7,819,229 RGD:9068941
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mylip myosin regulatory light chain interacting protein JBrowse link NW_004955483 9,725,343 9,745,041 RGD:9068941
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link NW_004955464 4,424,583 4,439,805 RGD:9068941
Wnt receptor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf43 ring finger protein 43 JBrowse link NW_004955451 4,604,985 4,680,762 RGD:9068941
G Znrf3 zinc and ring finger 3 JBrowse link NW_004955455 3,066,957 3,289,836 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11826
    metabolic process 7570
      catabolic process 1621
        cellular catabolic process 1416
          receptor catabolic process 27
            G protein-coupled receptor catabolic process 1
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 6
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 8
            regulation of receptor catabolic process + 12
Path 2
Term Annotations click to browse term
  biological_process 11826
    metabolic process 7570
      organic substance metabolic process 7273
        macromolecule metabolic process 6317
          cellular macromolecule metabolic process 5458
            receptor metabolic process 201
              receptor catabolic process 27
                G protein-coupled receptor catabolic process 1
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 6
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 8
                regulation of receptor catabolic process + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.