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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor catabolic process
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Accession:GO:0032801 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms:exact_synonym: receptor breakdown;   receptor catabolism;   receptor degradation



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receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 involved_in ISO (PMID:20643123) RGD PMID:20643123 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Capn1 calpain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3720432|PMID:17529984)
Ensembl
RGD
PMID:17529984 GO_REF:0000107 MGI:3720432 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Cdk5 cyclin-dependent kinase 5 acts_upstream_of_or_within ISO MGI:3720892|MGI:3720937 (MGI:3720432|PMID:17529984) RGD PMID:17529984 MGI:3720432 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Kif16b kinesin family member 16B involved_in ISO (PMID:15882625) RGD PMID:15882625 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
JBrowse link
G Lgmn legumain involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5008720|PMID:21292981)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21292981 GO_REF:0000024 GO_REF:0000107 MGI:5008720 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
JBrowse link
G Mvb12a multivesicular body subunit 12A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,252,227...18,257,111
Ensembl chr16:18,252,222...18,257,539
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:18544533)
Ensembl
RGD
PMID:18544533 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 involved_in ISO (PMID:20643123) RGD PMID:20643123 NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO
IEA
(PMID:20643123)
GO_REF:0000107
RGD
Ensembl
PMID:20643123 GO_REF:0000107 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:12151385) RGD PMID:12151385 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196)
(MGI:5545984|PMID:21266196)
RGD PMID:21266196 MGI:5545984 NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:17878231)
GO_REF:0000024
RGD
UniProt
PMID:17878231 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Uvrag UV radiation resistance associated involved_in ISO (PMID:20643123) RGD PMID:20643123 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136
JBrowse link
G protein-coupled receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn2 beclin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:23954414)
UniProtKB:Q5JY77 (PMID:23954414)
MGI:5550535 (MGI:5528919|PMID:23954414)
RGD PMID:23954414 MGI:5528919 NCBI chr13:87,843,528...87,892,343
Ensembl chr13:87,844,531...87,845,787
JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
UniProtKB:A8MW95 (PMID:23954414)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23954414 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:98,765,581...98,772,685
Ensembl chr  X:98,709,841...98,772,851
JBrowse link
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO
ISS
(PMID:16912035), (PMID:18197702)
PMID:12552133
GO_REF:0000024
RGD
UniProt
PMID:16912035 PMID:18197702 PMID:12552133 GO_REF:0000024, RGD:629554 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
RGD PMID:22848640 MGI:5446858 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA
(PMID:16912035)
GO_REF:0000107
RGD
Ensembl
PMID:16912035 GO_REF:0000107 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
negative regulation of receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:15950758)
GO_REF:0000107
RGD
Ensembl
PMID:15950758 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
positive regulation of receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:24790097) RGD PMID:24790097 NCBI chr11:64,814,926...64,824,538
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Git1 GIT ArfGAP 1 IMP RGD PMID:18523162 RGD:13513208 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116) RGD PMID:15514116 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:24790097) RGD PMID:24790097 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:4460047|PMID:20519653) RGD PMID:20519653 MGI:4460047 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:22045810) RGD PMID:22045810 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylip myosin regulatory light chain interacting protein involved_in ISO (MGI:3849777|PMID:19520913) RGD PMID:19520913 MGI:3849777 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO MGI:3577021 (MGI:3576461|PMID:15805190), (MGI:3583861|PMID:15741654) RGD PMID:15741654 PMID:15805190 MGI:3576461 MGI:3583861 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
Wnt receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf43 ring finger protein 43 involved_in IBA
ISO
PMID:21873635
(PMID:22895187)
RGD PMID:22895187 PMID:21873635 RGD:13792537 NCBI chr10:72,461,508...72,535,977
Ensembl chr10:72,464,348...72,536,977
JBrowse link
G Znrf3 zinc and ring finger 3 involved_in ISO (PMID:22575959) RGD PMID:22575959 NCBI chr14:80,157,854...80,313,456 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      catabolic process 2568
        cellular catabolic process 2206
          receptor catabolic process 30
            G protein-coupled receptor catabolic process 2
            Wnt receptor catabolic process 2
            low-density lipoprotein particle receptor catabolic process + 6
            negative regulation of receptor catabolic process + 3
            neurotransmitter receptor catabolic process 0
            positive regulation of receptor catabolic process + 9
            regulation of receptor catabolic process + 13
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        macromolecule metabolic process 9812
          cellular macromolecule metabolic process 8208
            receptor metabolic process 199
              receptor catabolic process 30
                G protein-coupled receptor catabolic process 2
                Wnt receptor catabolic process 2
                low-density lipoprotein particle receptor catabolic process + 6
                negative regulation of receptor catabolic process + 3
                neurotransmitter receptor catabolic process 0
                positive regulation of receptor catabolic process + 9
                regulation of receptor catabolic process + 13
paths to the root