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ONTOLOGY REPORT - ANNOTATIONS


Term:low-density lipoprotein receptor particle metabolic process
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Accession:GO:0032799 term browser browse the term
Definition:The chemical reactions and pathways involving low-density lipoprotein receptors.
Synonyms:exact_synonym: LDL receptor metabolic process;   low-density lipoprotein receptor metabolic process;   low-density lipoprotein receptor metabolism



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low-density lipoprotein receptor particle metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCSK9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO (MGI:3710922|PMID:17242417) MGI PMID:17242417 MGI:3710922 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:16912035), (PMID:18197702) HGNC-UCL PMID:16912035 PMID:18197702 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
negative regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IDA (PMID:16912035) HGNC-UCL PMID:16912035 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564
JBrowse link
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G APOE apolipoprotein E involved_in IDA (PMID:15950758) BHF-UCL PMID:15950758 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYLIP myosin regulatory light chain interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,129,086...16,151,015
Ensembl chr 6:16,129,086...16,148,248
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO (MGI:3583861|PMID:15741654)
(MGI:3576461|PMID:15805190)
MGI PMID:15741654 PMID:15805190 MGI:3576461 MGI:3583861 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18605
    metabolic process 11952
      cellular metabolic process 10867
        cellular macromolecule metabolic process 8305
          receptor metabolic process 200
            low-density lipoprotein receptor particle metabolic process 6
              low-density lipoprotein particle receptor catabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 18605
    metabolic process 11952
      organic substance metabolic process 11461
        macromolecule metabolic process 9891
          cellular macromolecule metabolic process 8305
            receptor metabolic process 200
              low-density lipoprotein receptor particle metabolic process 6
                low-density lipoprotein particle receptor catabolic process + 6
paths to the root