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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of DNA-templated transcription, elongation
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Accession:GO:0032785 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
Synonyms:exact_synonym: negative regulation of DNA-dependent transcription, elongation
 broad_synonym: down regulation of RNA elongation;   downregulation of RNA elongation;   inhibition of RNA elongation;   negative regulation of transcription elongation;   negative regulation of transcriptional elongation
 related_synonym: negative transcription elongation regulator activity


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negative regulation of DNA-templated transcription, elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit involved_in ISO (PMID:9450929), (PMID:9857195) UniProt PMID:9450929 PMID:9857195 NCBI chr17:52,420,503...52,427,514 JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:36,543,998...36,575,161
Ensembl chr19:45,092,075...45,122,335 		JBrowse link
G WDR82 WD repeat domain 82 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,196,740...52,220,982
Ensembl chr 3:53,426,112...53,450,170 		JBrowse link
G ZC3H4 zinc finger CCCH-type containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:44,054,086...44,103,981
Ensembl chr19:52,582,170...52,627,715 		JBrowse link
negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10318824), (PMID:19204372) Ensembl
MGI		 PMID:10318824 PMID:19204372 GO_REF:0000107 Ensembl chr16:278,239...337,891 JBrowse link
G EAPP E2F associated phosphoprotein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15716352) MGI
Ensembl		 PMID:15716352 GO_REF:0000107 NCBI chr14:15,273,149...15,297,241
Ensembl chr14:33,462,959...33,485,186 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:14580347) HGNC-UCL PMID:14580347 NCBI chr17:12,175,544...12,180,077
Ensembl chr17:12,353,590...12,354,669 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031 		JBrowse link
G NELFA negative elongation factor complex member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21670248) Ensembl
MGI
TreeGrafter		 PMID:21670248 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:2,119,699...2,147,618
Ensembl chr 4:2,027,939...2,054,669 		JBrowse link
G NELFB negative elongation factor complex member B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:108,314,535...108,333,050
Ensembl chr 9:137,278,964...137,301,751 		JBrowse link
G NELFCD negative elongation factor complex member C/D involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:55,332,309...55,346,167
Ensembl chr20:56,693,685...56,706,458 		JBrowse link
G NELFE negative elongation factor complex member E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21670248) Ensembl
MGI
TreeGrafter		 PMID:21670248 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:31,612,924...31,619,732
Ensembl chr 6:32,499,540...32,506,382 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:69,577,778...69,618,068
Ensembl chr17:75,128,325...75,168,254 		JBrowse link
G RNF168 ring finger protein 168 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:193,814,785...193,848,620
Ensembl chr 3:203,756,589...203,790,687 		JBrowse link
G RNF8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17284610) Ensembl
MGI		 PMID:17284610 GO_REF:0000107 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:6214653|PMID:25247314), (PMID:31399344) UniProt PMID:25247314 PMID:31399344 MGI:6214653 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within ISO (PMID:21670248) MGI PMID:21670248 NCBI chr17:52,420,503...52,427,514 JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      organic substance metabolic process 9869
        macromolecule metabolic process 8341
          macromolecule biosynthetic process 6490
            RNA biosynthetic process 3180
              DNA-templated transcription elongation 90
                negative regulation of DNA-templated transcription, elongation 20
                  negative regulation of transcription elongation by RNA polymerase I 0
                  negative regulation of transcription elongation by RNA polymerase II 17
Path 2
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      organic substance metabolic process 9869
        organic cyclic compound metabolic process 5562
          nucleobase-containing compound metabolic process 5109
            nucleic acid metabolic process 4613
              RNA metabolic process 4058
                RNA biosynthetic process 3180
                  DNA-templated transcription 3152
                    DNA-templated transcription elongation 90
                      regulation of DNA-templated transcription elongation 57
                        negative regulation of DNA-templated transcription, elongation 20
                          negative regulation of transcription elongation by RNA polymerase I 0
                          negative regulation of transcription elongation by RNA polymerase II 17
paths to the root