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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of interleukin-2 production
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Accession:GO:0032743 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.
Synonyms:exact_synonym: positive regulation of IL-2 production;   up regulation of interleukin-2 production;   upregulation of interleukin-2 production
 narrow_synonym: activation of interleukin-2 production;   positive regulation of interleukin-2 biosynthetic process;   positive regulation of interleukin-2 secretion;   stimulation of interleukin-2 production
 alt_id: GO:0045086;   GO:1900042


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positive regulation of interleukin-2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18025176) Ensembl
MGI		 PMID:18025176 GO_REF:0000107 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chr 1:179,099,330...179,229,677
Ensembl chr 1:179,099,330...179,229,684 		JBrowse link
G ANXA1 annexin A1 involved_in IDA
IEA		 (PMID:17008549) UniProt
TreeGrafter		 PMID:17008549 GO_REF:0000118 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G BTNL2 butyrophilin like 2 acts_upstream_of_or_within ISO (PMID:16751379) MGI PMID:16751379 NCBI chr 6:32,393,339...32,407,181
Ensembl chr 6:32,393,339...32,407,181 		JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO
IMP		 (PMID:12867038)
(PMID:12154360)		 Ensembl
MGI
UniProt		 PMID:12154360 PMID:12867038 GO_REF:0000107 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:24097820) MGI PMID:24097820 NCBI chr16:67,645,144...67,657,569
Ensembl chr16:67,644,988...67,657,569 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:10201995), (PMID:11754812), (PMID:14557411), (PMID:7538697) MGI PMID:7538697 PMID:10201995 PMID:11754812 PMID:14557411 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:16751379) MGI PMID:16751379 NCBI chr15:73,683,944...73,714,514
Ensembl chr15:73,683,966...73,714,514 		JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:7688139)
(PMID:3875683)		 Ensembl
MGI
UniProt		 PMID:3875683 PMID:7688139 GO_REF:0000107 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12874832) Ensembl
MGI		 PMID:12874832 GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD4 CD4 molecule involved_in NAS (PMID:1901411) UniProt PMID:1901411 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799 		JBrowse link
G CD80 CD80 molecule involved_in NAS (PMID:9915850) UniProt PMID:9915850 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD83 CD83 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15322158) Ensembl
MGI		 PMID:15322158 GO_REF:0000107 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918 		JBrowse link
G CD86 CD86 molecule involved_in NAS (PMID:9915850) UniProt PMID:9915850 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IDA
ISS		 (PMID:19358895) ARUK-UCL PMID:19358895 GO_REF:0000024 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G DEFB124 defensin beta 124 involved_in IDA (PMID:24955228) UniProt PMID:24955228 NCBI chr20:31,465,471...31,475,127
Ensembl chr20:31,465,471...31,476,757 		JBrowse link
G GLMN glomulin, FKBP associated protein involved_in
acts_upstream_of_or_within		 IMP
IDA		 (PMID:12604780) UniProt
MGI		 PMID:12604780 NCBI chr 1:92,246,402...92,370,844
Ensembl chr 1:92,246,402...92,298,987 		JBrowse link
G IL1A interleukin 1 alpha involved_in
acts_upstream_of		 IEA
ISS
IMP		 (PMID:31172560)
(PMID:2989698)		 Ensembl
ARUK-UCL
BHF-UCL		 PMID:2989698 PMID:31172560 GO_REF:0000107 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta involved_in IMP (PMID:2989698) BHF-UCL PMID:2989698 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IDA (PMID:12374808) UniProt PMID:12374808 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G MALT1 MALT1 paracaspase involved_in IMP (PMID:15125833) UniProt PMID:15125833 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IMP (PMID:15125833) UniProt PMID:15125833 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G PDE4B phosphodiesterase 4B involved_in IMP (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in IMP (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PNP purine nucleoside phosphorylase involved_in IMP (PMID:16930574) UniProt PMID:16930574 NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094 		JBrowse link
G PRKCQ protein kinase C theta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12867038) Ensembl
MGI		 PMID:12867038 GO_REF:0000107 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G PRKD2 protein kinase D2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G RPS3 ribosomal protein S3 involved_in IMP (PMID:18045535) CAFA PMID:18045535 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in IMP (PMID:17377532) UniProt PMID:17377532 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:129,779,949...129,795,201
Ensembl chr  X:129,779,949...129,795,201 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 involved_in IMP (PMID:24337748) UniProt PMID:24337748 NCBI chr 2:54,456,327...54,671,446
Ensembl chr 2:54,456,327...54,671,446 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:10072077) MGI PMID:10072077 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10072077) Ensembl
MGI		 PMID:10072077 GO_REF:0000107 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
G STOML2 stomatin like 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:35,099,776...35,103,195
Ensembl chr 9:35,099,776...35,103,195 		JBrowse link
G TNFSF4 TNF superfamily member 4 ISO RGD PMID:9790919 RGD:634509 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IMP (PMID:15125833) UniProt PMID:15125833 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IMP (PMID:15125833) UniProt PMID:15125833 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G VTCN1 V-set domain containing T cell activation inhibitor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16751379) Ensembl
MGI		 PMID:16751379 GO_REF:0000107 NCBI chr 1:117,143,587...117,210,927
Ensembl chr 1:117,143,587...117,210,960 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    multicellular organismal process 8501
      positive regulation of multicellular organismal process 2009
        positive regulation of cytokine production 568
          positive regulation of interleukin-2 production 42
Path 2
Term Annotations click to browse term
  biological_process 19770
    biological regulation 13405
      regulation of biological process 13030
        regulation of metabolic process 7344
          regulation of biosynthetic process 6134
            regulation of cellular biosynthetic process 6085
              regulation of macromolecule biosynthetic process 5939
                regulation of gene expression 5819
                  regulation of cytokine production 988
                    positive regulation of cytokine production 568
                      positive regulation of interleukin-2 production 42
paths to the root