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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of interleukin-2 production
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Accession:GO:0032743 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.
Synonyms:exact_synonym: positive regulation of IL-2 production;   up regulation of interleukin-2 production;   upregulation of interleukin-2 production
 narrow_synonym: activation of interleukin-2 production;   positive regulation of interleukin-2 biosynthetic process;   positive regulation of interleukin-2 secretion;   stimulation of interleukin-2 production
 alt_id: GO:0045086;   GO:1900042


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positive regulation of interleukin-2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87860 (PMID:18025176) RGD PMID:18025176 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87859 (PMID:18025176) RGD PMID:18025176 NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Anxa1 annexin A1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17008549)
GO_REF:0000107
GO_REF:0000118		 UniProt
RGD
Ensembl
TreeGrafter		 PMID:17008549 GO_REF:0000024 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Btnl2 butyrophilin-like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16751379)		 Ensembl
RGD		 PMID:16751379 GO_REF:0000107 NCBI chr20:4,490,169...4,504,002
Ensembl chr20:4,489,517...4,503,341 		JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in
acts_upstream_of_or_within		 ISO (PMID:12154360)
MGI:3039682 (PMID:12867038)		 RGD PMID:12154360 PMID:12867038 NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO MGI:4462559|MGI:5547539 (PMID:24097820) RGD PMID:24097820 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3699670|PMID:14662900)		 BHF-UCL
RGD		 PMID:14662900 GO_REF:0000024 MGI:3699670 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO (PMID:10201995), (PMID:11754812), (PMID:14557411), (PMID:7538697) RGD PMID:7538697 PMID:10201995 PMID:11754812 PMID:14557411 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Cd276 Cd276 molecule acts_upstream_of_or_within ISO (PMID:16751379) RGD PMID:16751379 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd28 Cd28 molecule involved_in
acts_upstream_of_or_within		 ISO
ISS
IEA		 (PMID:3875683)
GO_REF:0000024
GO_REF:0000107
MGI:1857150 (PMID:7688139)		 RGD
UniProt
Ensembl		 PMID:3875683 PMID:7688139 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:12874832) RGD PMID:12874832 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cd83 CD83 molecule acts_upstream_of_or_within ISO MGI:3055293 (PMID:15322158) RGD PMID:15322158 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19358895)
(MGI:3844414|PMID:19136564)		 RGD PMID:19136564 PMID:19358895 MGI:3844414 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Defb25 defensin beta 25 involved_in ISO (PMID:24955228) RGD PMID:24955228 NCBI chr 3:141,098,813...141,099,752
Ensembl chr 3:141,098,856...141,099,696 		JBrowse link
G Glmn glomulin, FKBP associated protein involved_in
acts_upstream_of_or_within		 ISO (PMID:12604780) RGD PMID:12604780 NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Il1a interleukin 1 alpha involved_in
acts_upstream_of		 ISO
IEA
IMP		 (PMID:2989698)
GO_REF:0000107
PMID:31172560		 RGD
Ensembl		 PMID:2989698 PMID:31172560 GO_REF:0000107, RGD:15023467 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:2989698) RGD PMID:2989698 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Irf4 interferon regulatory factor 4 involved_in ISO (PMID:12374808) RGD PMID:12374808 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO
IEA		 (PMID:17404263)
GO_REF:0000107		 RGD
Ensembl		 PMID:17404263 GO_REF:0000107 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO
IEA		 (PMID:17404263)
GO_REF:0000107		 RGD
Ensembl		 PMID:17404263 GO_REF:0000107 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA		 (MGI:3844414|PMID:19136564)
GO_REF:0000107		 RGD
Ensembl		 PMID:19136564 GO_REF:0000107 MGI:3844414 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pnp purine nucleoside phosphorylase involved_in ISO (PMID:16930574) RGD PMID:16930574 NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986 		JBrowse link
G Prkcq protein kinase C, theta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2664379 (PMID:12867038)		 Ensembl
RGD		 PMID:12867038 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4849903|PMID:20819079)		 UniProt
RGD		 PMID:20819079 GO_REF:0000024 MGI:4849903 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:P05480 (MGI:3530407|PMID:15661907) RGD PMID:15661907 MGI:3530407 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098) RGD PMID:11894098 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISO
IEA		 (PMID:17377532)
(MGI:3710039|PMID:17377532)
GO_REF:0000107		 RGD
Ensembl		 PMID:17377532 GO_REF:0000107 MGI:3710039 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (PMID:16227612) RGD PMID:16227612 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (PMID:10072077) RGD PMID:10072077 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103036 (PMID:10072077)		 Ensembl
RGD		 PMID:10072077 GO_REF:0000107 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stoml2 stomatin like 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5438519|PMID:23028053)		 UniProt
RGD		 PMID:23028053 GO_REF:0000024 MGI:5438519 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920 		JBrowse link
G Tnfsf4 TNF superfamily member 4 IDA RGD PMID:9790919 RGD:634509 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:15125833)
GO_REF:0000107		 RGD
Ensembl		 PMID:15125833 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 acts_upstream_of_or_within ISO (PMID:16751379) RGD PMID:16751379 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    multicellular organismal process 8921
      positive regulation of multicellular organismal process 1893
        positive regulation of cytokine production 537
          positive regulation of interleukin-2 production 39
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of metabolic process 6641
          regulation of biosynthetic process 5478
            regulation of cellular biosynthetic process 5386
              regulation of macromolecule biosynthetic process 5286
                regulation of gene expression 5170
                  regulation of cytokine production 910
                    positive regulation of cytokine production 537
                      positive regulation of interleukin-2 production 39
paths to the root