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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of interleukin-10 production
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Accession:GO:0032693 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.
Synonyms:exact_synonym: down regulation of interleukin-10 production;   downregulation of interleukin-10 production;   negative regulation of IL-10 production
 narrow_synonym: inhibition of interleukin-10 production;   negative regulation of interleukin-10 biosynthetic process;   negative regulation of interleukin-10 secretion
 alt_id: GO:0045081;   GO:2001180


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negative regulation of interleukin-10 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase involved_in ISO RGD
MGI		 PMID:28352114 GO_REF:0000096 MGI:4417868 RGD:151665126 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
G Cd274 CD274 antigen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd84 CD84 antigen involved_in IDA (MGI:5700297|PMID:20628063) UniProt PMID:20628063 MGI:5700297 NCBI chr 1:171,667,261...171,718,288
Ensembl chr 1:171,667,265...171,718,285 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within IMP (PMID:16926417) MGI PMID:16926417 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb acts_upstream_of_or_within IMP (PMID:12385742) MGI PMID:12385742 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:16275384) MGI PMID:16275384 GO_REF:0000119 MGI:4834177 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 acts_upstream_of_or_within IMP (PMID:19234212) MGI PMID:19234212 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Il12b interleukin 12b involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Il23r interleukin 23 receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:67,399,906...67,468,838
Ensembl chr 6:67,399,916...67,468,839 		JBrowse link
G Jak3 Janus kinase 3 involved_in IMP (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lilrb4a leukocyte immunoglobulin-like receptor, subfamily B, member 4A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707 		JBrowse link
G Lilrb4b leukocyte immunoglobulin-like receptor, subfamily B, member 4B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799 		JBrowse link
G Mir106a microRNA 106a involved_in
acts_upstream_of		 ISO (PMID:19307576) ARUK-UCL PMID:19307576 NCBI chr  X:51,831,380...51,831,444
Ensembl chr  X:51,831,380...51,831,444 		JBrowse link
G Mir194-1 microRNA 194-1 acts_upstream_of
involved_in		 ISO (PMID:26147452) ARUK-UCL PMID:26147452 NCBI chr 1:185,045,516...185,045,582
Ensembl chr 1:185,045,516...185,045,582 		JBrowse link
G Mir194-2 microRNA 194-2 acts_upstream_of
involved_in		 ISO (PMID:26147452) ARUK-UCL PMID:26147452 NCBI chr19:6,314,673...6,314,758
Ensembl chr19:6,314,673...6,314,758 		JBrowse link
G Mir98 microRNA 98 involved_in
acts_upstream_of
acts_upstream_of_or_within		 ISO
IDA		 (PMID:29702181)
(PMID:29702181), (PMID:31886314)
(PMID:21609717)		 ARUK-UCL
MGI		 PMID:21609717 PMID:29702181 PMID:31886314 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317 		JBrowse link
G Mirlet7c-1 microRNA let7c-1 acts_upstream_of
involved_in		 ISO (PMID:22835429) ARUK-UCL PMID:22835429 NCBI chr16:77,396,545...77,396,638
Ensembl chr16:77,396,545...77,396,638 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:29,388,319...29,450,327
Ensembl chr19:29,388,319...29,448,561 		JBrowse link
G Prg2 proteoglycan 2, bone marrow acts_upstream_of_or_within IMP (PMID:16926417) MGI PMID:16926417 NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976 		JBrowse link
G Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 involved_in IMP (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080 		JBrowse link
G Trib2 tribbles pseudokinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:15,841,726...15,866,963
Ensembl chr12:15,841,728...15,866,923 		JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein involved_in IMP (MGI:5638298|PMID:25690660) ARUK-UCL PMID:25690660 MGI:5638298 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    multicellular organismal process 8908
      negative regulation of multicellular organismal process 1440
        negative regulation of cytokine production 420
          negative regulation of interleukin-10 production 26
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13118
      regulation of biological process 12727
        regulation of metabolic process 6597
          regulation of biosynthetic process 5426
            regulation of cellular biosynthetic process 5336
              regulation of macromolecule biosynthetic process 5219
                regulation of gene expression 5099
                  regulation of cytokine production 977
                    negative regulation of cytokine production 420
                      negative regulation of interleukin-10 production 26
paths to the root