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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of chemokine production
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Accession:GO:0032682 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.
Synonyms:exact_synonym: down regulation of chemokine production;   downregulation of chemokine production
 narrow_synonym: inhibition of chemokine production;   negative regulation of chemokine biosynthetic process;   negative regulation of chemokine secretion
 alt_id: GO:0045079;   GO:0090198


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negative regulation of chemokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELANE elastase, neutrophil expressed involved_in ISO (PMID:12223522) UniProt PMID:12223522 NCBI chr19:276,499...280,598 JBrowse link
G EPHA2 EPH receptor A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19443703) Ensembl
MGI		 PMID:19443703 GO_REF:0000107 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12925700) MGI PMID:12925700 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) ARUK-UCL PMID:19380766 NCBI chr19:51,606,681...51,612,751 JBrowse link
G LOC100977210 galectin-9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G LOC103785028 polycomb protein SUZ12 ISO RGD PMID:23192652 RGD:9586745 NCBI chr17:24,790,921...24,853,790 JBrowse link
G SIGIRR single Ig and TIR domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:403,733...415,024
Ensembl chr11:442,468...448,959 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16891306) Ensembl
MGI		 PMID:16891306 GO_REF:0000107 NCBI chr11:113,862,537...113,869,447
Ensembl chr11:117,792,700...117,799,269 		JBrowse link
negative regulation of chemokine (C-C motif) ligand 4 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962 		JBrowse link
negative regulation of chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,543,522...110,578,463
Ensembl chr12:113,928,202...113,959,654
Ensembl chr12:113,928,202...113,959,654 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:110,935,649...110,960,019
Ensembl chr 5:116,734,092...116,734,799 		JBrowse link
negative regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLF4 KLF transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797 		JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 involved_in ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr15:46,493,139...46,760,271
Ensembl chr15:64,761,394...65,029,655 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,511,984...110,525,343
Ensembl chr12:113,896,760...113,921,814 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,543,522...110,578,463
Ensembl chr12:113,928,202...113,959,654
Ensembl chr12:113,928,202...113,959,654 		JBrowse link
negative regulation of chemokine (C-X-C motif) ligand 9 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,543,522...110,578,463
Ensembl chr12:113,928,202...113,959,654
Ensembl chr12:113,928,202...113,959,654 		JBrowse link
negative regulation of IP-10 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) ARUK-UCL PMID:19380766 NCBI chr19:51,606,681...51,612,751 JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,511,984...110,525,343
Ensembl chr12:113,896,760...113,921,814 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,543,522...110,578,463
Ensembl chr12:113,928,202...113,959,654
Ensembl chr12:113,928,202...113,959,654 		JBrowse link
negative regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,175,858...2,191,056
Ensembl chr16:3,353,666...3,368,970 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106 		JBrowse link
negative regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOD apolipoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:192,852,887...192,868,233
Ensembl chr 3:203,152,476...203,168,060 		JBrowse link
G C1QTNF3 C1q and TNF related 3 involved_in ISO (PMID:20739398) UniProt PMID:20739398 NCBI chr 5:76,292,679...76,325,064
Ensembl chr 5:81,687,891...81,742,003 		JBrowse link
G ERBIN erbb2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:47,929,305...48,081,381
Ensembl chr 5:49,589,418...49,676,689 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G LOC100982539 signal transducer CD24 involved_in ISO (MGI:5913663|PMID:19264983) UniProt PMID:19264983 MGI:5913663 NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (MGI:5659826|PMID:24255059) BHF-UCL PMID:24255059 MGI:5659826 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    multicellular organismal process 7188
      negative regulation of multicellular organismal process 1227
        negative regulation of cytokine production 314
          negative regulation of chemokine production 25
            negative regulation of IP-10 production 3
            negative regulation of chemokine (C-C motif) ligand 1 production 0
            negative regulation of chemokine (C-C motif) ligand 20 production 0
            negative regulation of chemokine (C-C motif) ligand 4 production 1
            negative regulation of chemokine (C-C motif) ligand 5 production 5
            negative regulation of chemokine (C-C motif) ligand 6 production 0
            negative regulation of chemokine (C-X-C motif) ligand 1 production 0
            negative regulation of chemokine (C-X-C motif) ligand 2 production 4
            negative regulation of chemokine (C-X-C motif) ligand 9 production 1
            negative regulation of fractalkine production 0
            negative regulation of macrophage inflammatory protein 1 alpha production 3
            negative regulation of macrophage inflammatory protein-1 gamma production 0
            negative regulation of monocyte chemotactic protein-1 production 7
Path 2
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological process 10982
        regulation of metabolic process 6061
          regulation of biosynthetic process 4939
            regulation of cellular biosynthetic process 4889
              regulation of macromolecule biosynthetic process 4751
                regulation of gene expression 4632
                  regulation of cytokine production 799
                    negative regulation of cytokine production 314
                      negative regulation of chemokine production 25
                        negative regulation of IP-10 production 3
                        negative regulation of chemokine (C-C motif) ligand 1 production 0
                        negative regulation of chemokine (C-C motif) ligand 20 production 0
                        negative regulation of chemokine (C-C motif) ligand 4 production 1
                        negative regulation of chemokine (C-C motif) ligand 5 production 5
                        negative regulation of chemokine (C-C motif) ligand 6 production 0
                        negative regulation of chemokine (C-X-C motif) ligand 1 production 0
                        negative regulation of chemokine (C-X-C motif) ligand 2 production 4
                        negative regulation of chemokine (C-X-C motif) ligand 9 production 1
                        negative regulation of fractalkine production 0
                        negative regulation of macrophage inflammatory protein 1 alpha production 3
                        negative regulation of macrophage inflammatory protein-1 gamma production 0
                        negative regulation of monocyte chemotactic protein-1 production 7
paths to the root