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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of interleukin-17 production
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Accession:GO:0032660 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
Synonyms:exact_synonym: regulation of CTLA-8 production;   regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion;   regulation of IL-17 production
 narrow_synonym: regulation of interleukin-17 biosynthetic process;   regulation of interleukin-17 secretion
 alt_id: GO:0045378;   GO:1905076



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negative regulation of interleukin-17 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5810834|PMID:27214549)
Ensembl
RGD
PMID:27214549 GO_REF:0000107 MGI:5810834 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 acts_upstream_of ISO (PMID:24038088) RGD PMID:24038088 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Foxp3 forkhead box P3 involved_in ISO (PMID:18368049)
(MGI:3795336|PMID:18368049)
RGD PMID:18368049 MGI:3795336 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18501882) RGD PMID:18501882 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha involved_in ISO UniProtKB:P35951 (MGI:5581894|PMID:22927332) RGD PMID:22927332 MGI:5581894 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Il36rn interleukin 36 receptor antagonist involved_in ISO (PMID:23147407) RGD PMID:23147407 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Mir125a microRNA 125a IMP RGD PMID:30972208 RGD:26884458 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir136 microRNA 136 involved_in ISO (PMID:30233690) RGD PMID:30233690 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177
JBrowse link
G Mir146b microRNA 146b involved_in ISO (PMID:30362152) RGD PMID:30362152 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:25962782) RGD PMID:25962782 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir20a microRNA 20a acts_upstream_of ISO (PMID:28972028) RGD PMID:28972028 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir383 microRNA 383 involved_in ISO (PMID:31648164) RGD PMID:31648164 NCBI chr16:54,040,340...54,040,413
Ensembl chr16:54,040,340...54,040,413
JBrowse link
G Mirlet7f-1 microRNA let7f-1 involved_in ISO (PMID:21508257) RGD PMID:21508257 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226
JBrowse link
G Mirlet7f2 microRNA let-7f-2 involved_in ISO (PMID:21508257) RGD PMID:21508257 NCBI chr  X:20,980,632...20,980,714
Ensembl chr  X:20,980,632...20,980,714
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(MGI:3818191|PMID:19015308)
UniProt
RGD
PMID:19015308 GO_REF:0000024 MGI:3818191 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Otud5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO MGI:1918040|MGI:2386448|MGI:5752247 (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr  X:14,626,173...14,659,331
Ensembl chr  X:14,626,164...14,659,573
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Prnp prion protein involved_in ISO (MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:4943618 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:3795336|PMID:18368049) RGD PMID:18368049 MGI:3795336 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (MGI:3611539|PMID:16239543) RGD PMID:16239543 MGI:3611539 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3773594|PMID:18203139), (MGI:4421230|PMID:20051628)
Ensembl
RGD
PMID:18203139 PMID:20051628 GO_REF:0000107 MGI:3773594 MGI:4421230 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18501882) RGD PMID:18501882 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:3706236 (MGI:5518492|PMID:24042119) RGD PMID:24042119 MGI:5518492 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 acts_upstream_of_or_within ISO MGI:1859615 (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
positive regulation of interleukin-17 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (MGI:5780752|PMID:27022145) RGD PMID:27022145 MGI:5780752 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISS
ISO
GO_REF:0000024
(PMID:26961233)
UniProt
RGD
PMID:26961233 GO_REF:0000024 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
JBrowse link
G Ccn1 cellular communication network factor 1 IMP RGD PMID:27653023 RGD:150429754 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16482511), (PMID:16751425), (PMID:17888176)
(PMID:16751425), (PMID:17888176)
RGD PMID:16482511 PMID:16751425 PMID:17888176 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il15 interleukin 15 involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA
(PMID:16482511)
GO_REF:0000107
RGD
Ensembl
PMID:16482511 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il2 interleukin 2 involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21 interleukin 21 involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:16482511), (PMID:16751425), (PMID:17888176)
(PMID:16751425), (PMID:17888176)
RGD PMID:16482511 PMID:16751425 PMID:17888176 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:6294413|PMID:25362566) RGD PMID:25362566 MGI:6294413 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ly9 lymphocyte antigen 9 involved_in ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:84,081,283...84,100,757
Ensembl chr13:84,079,458...84,100,823
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (MGI:3773594|PMID:18203139) RGD PMID:18203139 MGI:3773594 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:17919942) RGD PMID:17919942 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA
(PMID:21242261)
GO_REF:0000107
RGD
Ensembl
PMID:21242261 GO_REF:0000107 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Osm oncostatin M involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Phb1 prohibitin 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:31899195)
UniProt
RGD
PMID:31899195 GO_REF:0000024 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Prkcq protein kinase C, theta involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:3769226|PMID:16493044)
Ensembl
UniProt
RGD
PMID:16493044 GO_REF:0000024 GO_REF:0000107 MGI:3769226 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Rftn1 raftlin lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) RGD PMID:19414744 MGI:3850290 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
JBrowse link
G Slc7a5 solute carrier family 7 member 5 acts_upstream_of ISO (PMID:24038088) RGD PMID:24038088 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in IMP PMID:28284343 UniProt PMID:28284343 RGD:14397556 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:18453574)
GO_REF:0000024
(MGI:3851279|PMID:19501566)
RGD
UniProt
PMID:18453574 PMID:19501566 GO_REF:0000024 MGI:3851279 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5449456|PMID:23105140) RGD PMID:23105140 MGI:5449456 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
JBrowse link
positive regulation of interleukin-17A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    regulation of biological process 13160
      regulation of multicellular organismal process 3162
        regulation of cytokine production 857
          regulation of interleukin-17 production 50
            negative regulation of interleukin-17 production + 27
            positive regulation of interleukin-17 production + 25
            regulation of interleukin-17A production + 1
Path 2
Term Annotations click to browse term
  biological_process 20099
    metabolic process 12353
      organic substance metabolic process 11873
        macromolecule metabolic process 10218
          gene expression 6704
            cytokine production 864
              regulation of cytokine production 857
                regulation of interleukin-17 production 50
                  negative regulation of interleukin-17 production + 27
                  positive regulation of interleukin-17 production + 25
                  regulation of interleukin-17A production + 1
paths to the root