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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of interleukin-17 production
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Accession:GO:0032660 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
Synonyms:exact_synonym: regulation of CTLA-8 production;   regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion;   regulation of IL-17 production
 narrow_synonym: regulation of interleukin-17 biosynthetic process;   regulation of interleukin-17 secretion
 alt_id: GO:0045378;   GO:1905076


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negative regulation of interleukin-17 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5810834|PMID:27214549)		 Ensembl
RGD		 PMID:27214549 GO_REF:0000107 MGI:5810834 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:24038088)
GO_REF:0000107		 RGD
Ensembl		 PMID:24038088 GO_REF:0000107 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO (PMID:18368049)
(MGI:3795336|PMID:18368049)		 RGD PMID:18368049 MGI:3795336 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18501882) RGD PMID:18501882 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:16482511)
GO_REF:0000107		 RGD
Ensembl		 PMID:16482511 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha involved_in ISO UniProtKB:P35951 (MGI:5581894|PMID:22927332) RGD PMID:22927332 MGI:5581894 NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Il36rn interleukin 36 receptor antagonist involved_in ISO (PMID:23147407) RGD PMID:23147407 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Mir125a microRNA 125a IMP RGD PMID:30972208 RGD:26884458 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir136 microRNA 136 involved_in ISO (PMID:30233690) RGD PMID:30233690 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir146b microRNA 146b involved_in ISO (PMID:30362152) RGD PMID:30362152 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:25962782) RGD PMID:25962782 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir20a microRNA 20a acts_upstream_of ISO (PMID:28972028) RGD PMID:28972028 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir383 microRNA 383 involved_in ISO (PMID:31648164) RGD PMID:31648164 NCBI chr16:54,040,340...54,040,413
Ensembl chr16:54,040,340...54,040,413 		JBrowse link
G Mirlet7f-1 microRNA let7f-1 involved_in ISO (PMID:21508257) RGD PMID:21508257 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226 		JBrowse link
G Mirlet7f2 microRNA let-7f-2 involved_in ISO (PMID:21508257) RGD PMID:21508257 NCBI chr  X:20,980,632...20,980,714
Ensembl chr  X:20,980,632...20,980,714 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO		 GO_REF:0000024
(MGI:3818191|PMID:19015308)		 UniProt
RGD		 PMID:19015308 GO_REF:0000024 MGI:3818191 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Otud5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO MGI:1918040|MGI:2386448|MGI:5752247 (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr  X:14,626,173...14,659,331
Ensembl chr  X:14,626,164...14,659,573 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Prnp prion protein involved_in ISO (MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:4943618 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:3795336|PMID:18368049) RGD PMID:18368049 MGI:3795336 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (MGI:3611539|PMID:16239543) RGD PMID:16239543 MGI:3611539 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3773594|PMID:18203139), (MGI:4421230|PMID:20051628)		 Ensembl
RGD		 PMID:18203139 PMID:20051628 GO_REF:0000107 MGI:3773594 MGI:4421230 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18501882) RGD PMID:18501882 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:3706236 (MGI:5518492|PMID:24042119) RGD PMID:24042119 MGI:5518492 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 acts_upstream_of_or_within ISO MGI:1859615 (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr 7:69,115,216...69,224,843
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
positive regulation of interleukin-17 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (MGI:5780752|PMID:27022145) RGD PMID:27022145 MGI:5780752 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26961233)		 UniProt
RGD		 PMID:26961233 GO_REF:0000024 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccn1 cellular communication network factor 1 IMP RGD PMID:27653023 RGD:150429754 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16482511), (PMID:16751425), (PMID:17888176) RGD PMID:16482511 PMID:16751425 PMID:17888176 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 involved_in ISO
IEA		 (PMID:16482511)
GO_REF:0000107		 RGD
Ensembl		 PMID:16482511 GO_REF:0000107 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA		 (PMID:16482511)
GO_REF:0000107		 RGD
Ensembl		 PMID:16482511 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il2 interleukin 2 involved_in ISO (PMID:16482511) RGD PMID:16482511 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il21 interleukin 21 involved_in ISO
IEA		 (PMID:16482511)
GO_REF:0000107		 RGD
Ensembl		 PMID:16482511 GO_REF:0000107 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:16482511), (PMID:16751425), (PMID:17888176) RGD PMID:16482511 PMID:16751425 PMID:17888176 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:6294413|PMID:25362566) RGD PMID:25362566 MGI:6294413 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ly9 lymphocyte antigen 9 involved_in ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:84,079,345...84,100,783
Ensembl chr13:84,079,458...84,100,823 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (MGI:3773594|PMID:18203139) RGD PMID:18203139 MGI:3773594 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:17919942) RGD PMID:17919942 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA		 (PMID:21242261)
GO_REF:0000107		 RGD
Ensembl		 PMID:21242261 GO_REF:0000107 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Osm oncostatin M acts_upstream_of ISO (PMID:28972028) RGD PMID:28972028 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Phb1 prohibitin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:31899195)		 UniProt
RGD		 PMID:31899195 GO_REF:0000024 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Prkcq protein kinase C, theta involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3769226|PMID:16493044)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16493044 GO_REF:0000024 GO_REF:0000107 MGI:3769226 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) RGD PMID:19414744 MGI:3850290 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 acts_upstream_of ISO (PMID:24038088) RGD PMID:24038088 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in IMP PMID:28284343 UniProt PMID:28284343 RGD:14397556 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:18453574)
(MGI:3851279|PMID:19501566)
GO_REF:0000024		 RGD
UniProt		 PMID:18453574 PMID:19501566 GO_REF:0000024 MGI:3851279 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5449456|PMID:23105140) RGD PMID:23105140 MGI:5449456 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
positive regulation of interleukin-17A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    multicellular organismal process 9177
      regulation of multicellular organismal process 3336
        regulation of cytokine production 899
          regulation of interleukin-17 production 50
            negative regulation of interleukin-17 production + 27
            positive regulation of interleukin-17 production + 25
            regulation of interleukin-17A production + 1
Path 2
Term Annotations click to browse term
  biological_process 19553
    biological regulation 13187
      regulation of biological process 12813
        regulation of cellular process 12294
          regulation of cellular metabolic process 5918
            regulation of cellular biosynthetic process 5196
              regulation of macromolecule biosynthetic process 5050
                regulation of gene expression 4936
                  regulation of cytokine production 899
                    regulation of interleukin-17 production 50
                      negative regulation of interleukin-17 production + 27
                      positive regulation of interleukin-17 production + 25
                      regulation of interleukin-17A production + 1
paths to the root