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ONTOLOGY REPORT - ANNOTATIONS

Term:interleukin-8 production
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Accession:GO:0032637 term browser browse the term
Definition:The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-8 production
 narrow_synonym: interleukin-8 biosynthetic process;   interleukin-8 secretion
 alt_id: GO:0042228;   GO:0072606

show annotations for term's descendants           Sort by:
 
negative regulation of interleukin-8 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 ISO (PMID:22056994) RGD PMID:22056994 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012 		JBrowse link
G Anxa4 annexin A4 ISO
IEA		 (PMID:22056994)
GO_REF:0000107		 RGD
Ensembl		 PMID:22056994 GO_REF:0000107 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580 		JBrowse link
G Arrb1 arrestin, beta 1 ISO (PMID:16378096) RGD PMID:16378096 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139 		JBrowse link
G Bcl3 BCL3, transcription coactivator ISO (PMID:16306601) RGD PMID:16306601 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831 		JBrowse link
G Bpi bactericidal/permeability-increasing protein ISO
IBA		 (PMID:8409400)
PMID:21873635		 RGD PMID:8409400, PMID:21873635 RGD:13792537 NCBI chr 3:154,741,627...154,768,584
Ensembl chr 3:154,741,631...154,768,640 		JBrowse link
G Cactin cactin, spliceosome C complex subunit ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:11,258,526...11,266,509
Ensembl chr 7:11,261,201...11,266,630 		JBrowse link
G Cd33 CD33 molecule ISO (PMID:15597323) RGD PMID:15597323 NCBI chr 1:98,388,811...98,403,539
Ensembl chr 1:98,398,660...98,402,968 		JBrowse link
G Elane elastase, neutrophil expressed ISO (PMID:12223522) RGD PMID:12223522 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232 		JBrowse link
G Klf4 Kruppel like factor 4 ISO (PMID:20551324) RGD PMID:20551324 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 ISO (PMID:22700971) RGD PMID:22700971 NCBI chr 3:111,767,126...111,817,103
Ensembl chr 3:111,767,161...111,818,089 		JBrowse link
G Otud7b OTU deubiquitinase 7B ISO
ISS		 (PMID:21097510)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:21097510 GO_REF:0000024 NCBI chr 2:198,231,353...198,302,220
Ensembl chr 2:198,231,291...198,300,201 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO (PMID:23991106)
(MGI:5640942|PMID:23991106)		 RGD PMID:23991106 MGI:5640942 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348 		JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains ISO (MGI:4939978|PMID:21217009) RGD PMID:21217009 MGI:4939978 NCBI chr 1:72,443,750...72,462,293
Ensembl chr 1:72,443,758...72,461,547 		JBrowse link
G Tlr6 toll-like receptor 6 ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446 		JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:17128265) RGD PMID:17128265 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked ISO (PMID:21343177) RGD PMID:21343177 NCBI chr  X:28,593,405...28,617,267
Ensembl chr  X:28,593,405...28,595,395 		JBrowse link
positive regulation of interleukin-8 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS		 (PMID:19524870)
GO_REF:0000024		 RGD
UniProt		 PMID:19524870 GO_REF:0000024 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Afap1l2 actin filament associated protein 1-like 2 ISO
IBA		 (PMID:17412687)
PMID:21873635		 RGD PMID:17412687, PMID:21873635 RGD:13792537 NCBI chr 1:277,730,760...277,827,299
Ensembl chr 1:277,730,760...277,827,269 		JBrowse link
G Apoa2 apolipoprotein A2 ISO
ISS		 (PMID:11591715)
GO_REF:0000024		 RGD
UniProt		 PMID:11591715 GO_REF:0000024 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor ISO
ISS		 (PMID:17095757)
GO_REF:0000024		 RGD
UniProt		 PMID:17095757 GO_REF:0000024 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957 		JBrowse link
G Calca calcitonin-related polypeptide alpha ISO (PMID:16904178) RGD PMID:16904178 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Camp cathelicidin antimicrobial peptide ISO (PMID:14978112) RGD PMID:14978112 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518 		JBrowse link
G Cd14 CD14 molecule ISO (PMID:15039339) RGD PMID:15039339 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd2 Cd2 molecule ISO (PMID:19109405) RGD PMID:19109405 NCBI chr 2:203,666,706...203,680,073
Ensembl chr 2:203,666,637...203,680,083 		JBrowse link
G Cd244 CD244 molecule ISO (PMID:8376943) RGD PMID:8376943 NCBI chr13:89,959,091...89,995,993
Ensembl chr13:89,975,267...89,995,974 		JBrowse link
G Cd74 CD74 molecule ISO (PMID:24569872) RGD PMID:24569872 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849 		JBrowse link
G Clec7a C-type lectin domain containing 7A ISO (PMID:25251945) RGD PMID:25251945 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20829347)		 Ensembl
UniProt
RGD		 PMID:20829347 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Ddx58 DEXD/H-box helicase 58 ISO (PMID:24409285) RGD PMID:24409285 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772 		JBrowse link
G Elane elastase, neutrophil expressed ISO (PMID:14730209) RGD PMID:14730209 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232 		JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO
IEA
ISS		 (PMID:17404307)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17404307 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO
ISS		 (PMID:15155775), (PMID:17404307), (PMID:18622013), (PMID:19865078)
GO_REF:0000024		 RGD
UniProt		 PMID:15155775 PMID:17404307 PMID:18622013 PMID:19865078 GO_REF:0000024 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275 		JBrowse link
G F3 coagulation factor III, tissue factor ISO
IEA		 (PMID:22556343)
GO_REF:0000107		 RGD
Ensembl		 PMID:22556343 GO_REF:0000107 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Fadd Fas associated via death domain ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628 		JBrowse link
G Fcna ficolin A ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272 		JBrowse link
G Fcnb ficolin B ISO (PMID:21037097) RGD PMID:21037097 NCBI chr 3:6,617,816...6,626,193
Ensembl chr 3:6,617,751...6,626,284 		JBrowse link
G Ffar2 free fatty acid receptor 2 ISO
ISS		 (PMID:21037097)
GO_REF:0000024		 RGD
UniProt		 PMID:21037097 GO_REF:0000024 NCBI chr 1:89,268,197...89,271,942
Ensembl chr 1:89,268,938...89,269,930 		JBrowse link
G Gdf2 growth differentiation factor 2 ISO (PMID:19366699) RGD PMID:19366699 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239 		JBrowse link
G Hmgb1 high mobility group box 1 IDA
ISO		 PMID:10952726
(PMID:26961863)		 RGD PMID:26961863, PMID:10952726 RGD:10054071 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Hyal2 hyaluronidase 2 ISO
IEA
ISS		 (PMID:19443707)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19443707 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:116,324,062...116,328,978
Ensembl chr 8:116,324,040...116,328,978 		JBrowse link
G Il17d interleukin 17D ISO (PMID:12097364) RGD PMID:12097364 NCBI chr15:37,790,211...37,807,653
Ensembl chr15:37,790,141...37,807,660 		JBrowse link
G Il18 interleukin 18 IDA RGD PMID:18547159 RGD:4889457 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1b interleukin 1 beta IEA
ISO		 GO_REF:0000107
(PMID:19524870)		 Ensembl
RGD		 PMID:19524870 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 ISO RNAcentral:URS00004E0808_9606 (PMID:31886314) RGD PMID:31886314 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 ISO UniProtKB:Q04206 (PMID:21343296) RGD PMID:21343296 NCBI chr 2:210,034,095...210,039,451
Ensembl chr 2:210,034,095...210,039,451 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO
IEA		 (PMID:8409400)
GO_REF:0000107		 RGD
Ensembl		 PMID:8409400 GO_REF:0000107 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464 		JBrowse link
G Lgals9 galectin 9 ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201 		JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO (PMID:20219467) RGD PMID:20219467 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 ISO (PMID:22672233) RGD PMID:22672233 NCBI chr 1:173,521,412...173,528,969
Ensembl chr 1:173,520,413...173,528,943 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO
IEA		 (PMID:15653568)
GO_REF:0000107		 RGD
Ensembl		 PMID:15653568 GO_REF:0000107 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (PMID:24790089) RGD PMID:24790089 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492 		JBrowse link
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS		 (PMID:21097510)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:21097510 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724 		JBrowse link
G Pla2g1b phospholipase A2 group IB ISO (PMID:15528384) RGD PMID:15528384 NCBI chr12:46,879,346...46,890,234
Ensembl chr12:46,879,343...46,889,082 		JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:72,395,194...72,401,254
Ensembl chr 3:72,395,218...72,401,318 		JBrowse link
G Prkd2 protein kinase D2 ISO
ISS		 (PMID:16928771)
GO_REF:0000024		 RGD
UniProt		 PMID:16928771 GO_REF:0000024 NCBI chr 1:78,767,911...78,796,223
Ensembl chr 1:78,767,911...78,796,231 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:15944932 RGD:10003098 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448 		JBrowse link
G Pycard PYD and CARD domain containing ISO (PMID:16982856) RGD PMID:16982856 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO UniProtKB:O43504 (PMID:21343296) RGD PMID:21343296 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO (PMID:16127453) RGD PMID:16127453 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904 		JBrowse link
G Serpine1 serpin family E member 1 ISO
IEA		 (PMID:19916862)
GO_REF:0000107		 RGD
Ensembl		 PMID:19916862 GO_REF:0000107 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RNAcentral:URS00004E0808_9606|UniProtKB:P05231 (PMID:31886314) RGD PMID:31886314 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Syk spleen associated tyrosine kinase ISO
IEA		 (PMID:25251945)
GO_REF:0000107		 RGD
Ensembl		 PMID:25251945 GO_REF:0000107 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
G Tirap TIR domain containing adaptor protein ISO (PMID:16301656)
(MGI:3713420|PMID:16301656)		 RGD PMID:16301656 MGI:3713420 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224 		JBrowse link
G Tlr1 toll-like receptor 1 ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991 		JBrowse link
G Tlr2 toll-like receptor 2 ISO ComplexPortal:CPX-1134 (PMID:17128265), (PMID:19740627), (PMID:22198949) RGD PMID:17128265 PMID:19740627 PMID:22198949 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr3 toll-like receptor 3 ISO (PMID:17128265) RGD PMID:17128265 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214 		JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO		 GO_REF:0000107
(PMID:17951129), (PMID:19740627), (PMID:21329689)		 Ensembl
RGD		 PMID:17951129 PMID:19740627 PMID:21329689 GO_REF:0000107 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tlr5 toll-like receptor 5 ISO (PMID:17128265) RGD PMID:17128265 NCBI chr13:101,364,784...101,385,764
Ensembl chr13:101,381,510...101,385,764 		JBrowse link
G Tlr7 toll-like receptor 7 ISO (PMID:16188996), (PMID:19740627) RGD PMID:16188996 PMID:19740627 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957 		JBrowse link
G Tlr8 toll-like receptor 8 ISO (PMID:16188996) RGD PMID:16188996 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803 		JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:17128265), (PMID:19740627), (PMID:24409285) RGD PMID:17128265 PMID:19740627 PMID:24409285 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171 		JBrowse link
G Tnf tumor necrosis factor ISO RNAcentral:URS00004DA9DB_9606 (PMID:20551324), (PMID:23608026), (PMID:24790089), (PMID:31824476) RGD PMID:20551324 PMID:23608026 PMID:24790089 PMID:31824476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO		 GO_REF:0000107
(MGI:5009385|PMID:18174455)		 Ensembl
RGD		 PMID:18174455 GO_REF:0000107 MGI:5009385 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
G Zfp580 zinc finger protein 580 ISO (PMID:21830064) RGD PMID:21830064 NCBI chr 1:72,338,468...72,340,636
Ensembl chr 1:72,338,877...72,339,395 		JBrowse link
regulation of interleukin-8 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar2 complement component 5a receptor 2 ISO
ISS		 (PMID:22496247)
GO_REF:0000024		 RGD
UniProt		 PMID:22496247 GO_REF:0000024 NCBI chr 1:78,165,155...78,183,426
Ensembl chr 1:78,166,810...78,180,216 		JBrowse link
G Crp C-reactive protein ISO
ISS		 (PMID:21037097)
GO_REF:0000024		 RGD
UniProt		 PMID:21037097 GO_REF:0000024 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Il17f interleukin 17F ISO
IEA		 (PMID:11574464)
GO_REF:0000107		 RGD
Ensembl		 PMID:11574464 GO_REF:0000107 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO (PMID:12100025) RGD PMID:12100025 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692 		JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains ISO (MGI:4939978|PMID:21217009) RGD PMID:21217009 MGI:4939978 NCBI chr 1:72,443,750...72,462,293
Ensembl chr 1:72,443,758...72,461,547 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    multicellular organismal process 9040
      cytokine production 740
        interleukin-8 production 80
          negative regulation of interleukin-8 production 17
          positive regulation of interleukin-8 production 61
          regulation of interleukin-8 production + 80
Path 2
Term Annotations click to browse term
  biological_process 20044
    metabolic process 12101
      organic substance metabolic process 11622
        macromolecule metabolic process 10033
          gene expression 6358
            cytokine production 740
              interleukin-8 production 80
                negative regulation of interleukin-8 production 17
                positive regulation of interleukin-8 production 61
                regulation of interleukin-8 production + 80
paths to the root