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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-23 production
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Accession:GO:0032627 term browser browse the term
Definition:The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-23 production
 narrow_synonym: interleukin-23 biosynthetic process;   interleukin-23 secretion
 alt_id: GO:0042240;   GO:0072621



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negative regulation of interleukin-23 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rac1 Rac family small GTPase 1 involved_in ISO
IEA
(PMID:16982892)
GO_REF:0000107
RGD
Ensembl
PMID:16982892 GO_REF:0000107 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3773594|PMID:18203139)
Ensembl
RGD
PMID:18203139 GO_REF:0000107 MGI:3773594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
positive regulation of interleukin-23 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:3844414|PMID:19136564) RGD PMID:19136564 MGI:3844414 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:20027291) RGD PMID:20027291 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:20027291) RGD PMID:20027291 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il17a interleukin 17A involved_in ISO
IEA
(PMID:21145111)
GO_REF:0000107
RGD
Ensembl
PMID:21145111 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17ra interleukin 17 receptor A involved_in ISO (PMID:21145111) RGD PMID:21145111 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (MGI:3773594|PMID:18203139) RGD PMID:18203139 MGI:3773594 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA
(MGI:3844414|PMID:19136564)
GO_REF:0000107
RGD
Ensembl
PMID:19136564 GO_REF:0000107 MGI:3844414 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
regulation of interleukin-23 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:3795336|PMID:18368049) RGD PMID:18368049 MGI:3795336 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    multicellular organismal process 8887
      cytokine production 913
        interleukin-23 production 10
          negative regulation of interleukin-23 production 2
          positive regulation of interleukin-23 production 7
          regulation of interleukin-23 production + 10
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      organic substance metabolic process 11221
        macromolecule metabolic process 9473
          macromolecule biosynthetic process 7370
            gene expression 6922
              cytokine production 913
                interleukin-23 production 10
                  negative regulation of interleukin-23 production 2
                  positive regulation of interleukin-23 production 7
                  regulation of interleukin-23 production + 10
paths to the root