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ONTOLOGY REPORT - ANNOTATIONS

Term:interleukin-23 production
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Accession:GO:0032627 term browser browse the term
Definition:The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-23 production
 narrow_synonym: interleukin-23 biosynthetic process;   interleukin-23 secretion
 alt_id: GO:0042240;   GO:0072621


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negative regulation of interleukin-23 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rac1 Rac family small GTPase 1 involved_in ISO
IEA		 (PMID:16982892)
GO_REF:0000107		 RGD
Ensembl		 PMID:16982892 GO_REF:0000107 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3773594|PMID:18203139)		 Ensembl
RGD		 PMID:18203139 GO_REF:0000107 MGI:3773594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of interleukin-23 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:20027291) RGD PMID:20027291 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:20027291) RGD PMID:20027291 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il17a interleukin 17A involved_in ISO
IEA		 (PMID:21145111)
GO_REF:0000107		 RGD
Ensembl		 PMID:21145111 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17ra interleukin 17 receptor A involved_in ISO (PMID:21145111) RGD PMID:21145111 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (MGI:3773594|PMID:18203139) RGD PMID:18203139 MGI:3773594 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA		 (MGI:3844414|PMID:19136564)
GO_REF:0000107		 RGD
Ensembl		 PMID:19136564 GO_REF:0000107 MGI:3844414 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
regulation of interleukin-23 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:3795336|PMID:18368049) RGD PMID:18368049 MGI:3795336 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    multicellular organismal process 8951
      cytokine production 865
        interleukin-23 production 9
          negative regulation of interleukin-23 production 2
          positive regulation of interleukin-23 production 6
          regulation of interleukin-23 production + 9
Path 2
Term Annotations click to browse term
  biological_process 20091
    metabolic process 12359
      organic substance metabolic process 11881
        macromolecule metabolic process 10222
          gene expression 6697
            cytokine production 865
              interleukin-23 production 9
                negative regulation of interleukin-23 production 2
                positive regulation of interleukin-23 production 6
                regulation of interleukin-23 production + 9
paths to the root