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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-2 production
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Accession:GO:0032623 term browser browse the term
Definition:The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-2 production


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interleukin-2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd247 CD247 antigen JBrowse link 1 165,779,952 165,871,153 RGD:2290270
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide JBrowse link 1 171,229,572 171,234,349 RGD:2290270
G Oscar osteoclast associated receptor JBrowse link 7 3,609,813 3,616,157 RGD:2290270
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 JBrowse link 1 74,375,014 74,386,057 RGD:2290270
G Stoml2 stomatin (Epb7.2)-like 2 JBrowse link 4 43,027,690 43,031,976 RGD:2290270
interleukin-2 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1rap interleukin 1 receptor accessory protein JBrowse link 16 26,581,509 26,730,128 RGD:2290270
G Pawr PRKC, apoptosis, WT1, regulator JBrowse link 10 108,332,189 108,414,391 RGD:2290270
interleukin-2 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card11 caspase recruitment domain family, member 11 JBrowse link 5 140,872,999 141,000,596 RGD:2290270
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 19 55,067,635 55,127,319 RGD:2290270
negative regulation of interleukin-2 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd276 CD276 antigen JBrowse link 9 58,524,300 58,555,033 RGD:2290270
G Foxp3 forkhead box P3 JBrowse link X 7,579,676 7,595,243 RGD:2290270
G Lag3 lymphocyte-activation gene 3 JBrowse link 6 124,904,359 124,912,434 RGD:2290270
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:2290270
negative regulation of interleukin-2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 JBrowse link 7 25,461,702 25,477,647 RGD:2290270
G Foxp3 forkhead box P3 JBrowse link X 7,579,676 7,595,243 RGD:2290270
G Gata3 GATA binding protein 3 JBrowse link 2 9,857,078 9,887,953 RGD:2290270
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 11 46,454,931 46,481,255 RGD:2290270
G Hdac7 histone deacetylase 7 JBrowse link 15 97,792,661 97,844,502 RGD:2290270
G Homer2 homer scaffolding protein 2 JBrowse link 7 81,600,481 81,706,925 RGD:2290270
G Homer3 homer scaffolding protein 3 JBrowse link 8 70,282,880 70,294,361 RGD:2290270
G Il20rb interleukin 20 receptor beta JBrowse link 9 100,457,719 100,486,473 RGD:2290270
G Kat5 K(lysine) acetyltransferase 5 JBrowse link 19 5,603,014 5,611,556 RGD:2290270
G Nav3 neuron navigator 3 JBrowse link 10 109,681,260 110,455,722 RGD:2290270
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 8 88,647,315 88,688,474 RGD:2290270
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:2290270
G Prnp prion protein JBrowse link 2 131,909,928 131,938,436 RGD:2290270
G Sftpd surfactant associated protein D JBrowse link 14 41,172,212 41,185,198 RGD:2290270
G Tbx21 T-box 21 JBrowse link 11 97,098,007 97,115,331 RGD:2290270
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 JBrowse link 10 19,000,910 19,015,410 RGD:2290270
G Vsig4 V-set and immunoglobulin domain containing 4 JBrowse link X 96,247,201 96,293,438 RGD:2290270
G Xcl1 chemokine (C motif) ligand 1 JBrowse link 1 164,931,644 164,935,522 RGD:2290270
negative regulation of interleukin-2 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 antigen JBrowse link 1 194,938,821 194,961,292 RGD:2290270
G Ezr ezrin JBrowse link 17 6,738,131 6,782,780 RGD:2290270
G Trim27 tripartite motif-containing 27 JBrowse link 13 21,179,450 21,194,723 RGD:2290270
positive regulation of interleukin-2 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card11 caspase recruitment domain family, member 11 JBrowse link 5 140,872,999 141,000,596 RGD:2290270
G Cd1d1 CD1d1 antigen JBrowse link 3 86,995,834 87,012,358 RGD:2290270
G Cd28 CD28 antigen JBrowse link 1 60,746,388 60,773,359 RGD:2290270
G Cd3e CD3 antigen, epsilon polypeptide JBrowse link 9 44,998,735 45,009,663 RGD:2290270
G Glmn glomulin, FKBP associated protein JBrowse link 5 107,548,962 107,597,888 RGD:2290270
G Il1a interleukin 1 alpha JBrowse link 2 129,299,609 129,310,186 RGD:2290270
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:2290270
G Irf4 interferon regulatory factor 4 JBrowse link 13 30,749,233 30,766,981 RGD:2290270
G Prkcq protein kinase C, theta JBrowse link 2 11,171,905 11,301,226 RGD:2290270
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
G Stat5a signal transducer and activator of transcription 5A JBrowse link 11 100,859,351 100,885,169 RGD:2290270
G Stat5b signal transducer and activator of transcription 5B JBrowse link 11 100,780,731 100,859,004 RGD:2290270
positive regulation of interleukin-2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 19 20,373,434 20,390,671 RGD:2290270
G Ccr2 chemokine (C-C motif) receptor 2 JBrowse link 9 124,101,918 124,109,140 RGD:2290270
G Cd83 CD83 antigen JBrowse link 13 43,785,112 43,803,133 RGD:2290270
G Malt1 MALT1 paracaspase JBrowse link 18 65,430,939 65,478,888 RGD:2290270
G Pde4b phosphodiesterase 4B, cAMP specific JBrowse link 4 102,087,332 102,607,262 RGD:2290270
G Prkd2 protein kinase D2 JBrowse link 7 16,842,902 16,870,461 RGD:2290270
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 JBrowse link 4 16,122,732 16,163,678 RGD:2290270
G Rps3 ribosomal protein S3 JBrowse link 7 99,477,896 99,483,709 RGD:2290270
G Runx1 runt related transcription factor 1 JBrowse link 16 92,601,466 92,826,074 RGD:2290270
G Sash3 SAM and SH3 domain containing 3 JBrowse link X 48,146,436 48,161,565 RGD:2290270
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 JBrowse link 1 161,395,438 161,418,206 RGD:2290270
G Traf2 TNF receptor-associated factor 2 JBrowse link 2 25,517,982 25,546,940 RGD:2290270
G Traf6 TNF receptor-associated factor 6 JBrowse link 2 101,678,420 101,701,668 RGD:2290270
positive regulation of interleukin-2 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase JBrowse link 2 31,688,244 31,807,093 RGD:2290270
G Abl2 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) JBrowse link 1 156,558,590 156,649,619 RGD:2290270
G Btnl2 butyrophilin-like 2 JBrowse link 17 34,354,789 34,369,492 RGD:2290270
G Carmil2 capping protein regulator and myosin 1 linker 2 JBrowse link 8 105,686,010 105,698,195 RGD:2290270
G Cd276 CD276 antigen JBrowse link 9 58,524,300 58,555,033 RGD:2290270
G Sptbn1 spectrin beta, non-erythrocytic 1 JBrowse link 11 30,099,395 30,268,384 RGD:2290270
G Vtcn1 V-set domain containing T cell activation inhibitor 1 JBrowse link 3 100,825,459 100,896,922 RGD:2290270
regulation of interleukin-2 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card9 caspase recruitment domain family, member 9 JBrowse link 2 26,352,171 26,360,945 RGD:2290270
G Clec2i C-type lectin domain family 2, member i JBrowse link 6 128,887,582 128,898,167 RGD:2290270
G Il17f interleukin 17F JBrowse link 1 20,777,146 20,785,274 RGD:2290270

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  biological_process 23017
    multicellular organismal process 8218
      cytokine production 762
        interleukin-2 production 66
          interleukin-2 biosynthetic process + 21
          interleukin-2 secretion + 12
          negative regulation of interleukin-2 production + 25
          positive regulation of interleukin-2 production + 32
          regulation of interleukin-2 production + 58
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.