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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphoprotein phosphatase activity
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Accession:GO:0032515 term browser browse the term
Definition:Any process that stops or reduces the activity of a phosphoprotein phosphatase.
Synonyms:exact_synonym: down regulation of phosphoprotein phosphatase activity;   downregulation of phosphoprotein phosphatase activity
 narrow_synonym: down regulation of calcineurin activity;   down regulation of protein phosphatase type 2A activity;   down regulation of protein phosphatase type 2B activity;   downregulation of calcineurin activity;   downregulation of protein phosphatase type 2A activity;   downregulation of protein phosphatase type 2B activity;   inhibition of calcineurin activity;   inhibition of phosphoprotein phosphatase activity;   inhibition of protein phosphatase type 2A activity;   inhibition of protein phosphatase type 2B activity;   negative regulation of calcineurin activity;   negative regulation of protein phosphatase type 2A activity;   negative regulation of protein phosphatase type 2B activity
 related_synonym: down regulation of protein phosphatase 2 activity;   down regulation of protein phosphatase 3 activity;   downregulation of protein phosphatase 2 activity;   downregulation of protein phosphatase 3 activity;   inhibition of protein phosphatase 2 activity;   inhibition of protein phosphatase 3 activity;   negative regulation of protein phosphatase 2 activity;   regulation of protein phosphatase 3 activity
 alt_id: GO:0032513;   GO:0034048


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negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in IBA
ISO
PMID:21873635
(PMID:24157919)
RGD PMID:24157919, PMID:21873635 RGD:13792537 NCBI chr10:16,259,728...16,266,069
Ensembl chr10:16,259,728...16,266,061
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:73,738,137...73,792,935
Ensembl chr14:73,738,137...73,791,656
JBrowse link
G Cmya5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:22,646,694...22,744,536
Ensembl chr 2:22,646,712...22,744,407
JBrowse link
G Cry2 cryptochrome circadian regulator 2 involved_in ISO
IEA
(PMID:9383998)
GO_REF:0000107
RGD
Ensembl
PMID:9383998 GO_REF:0000107 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like involved_in ISO (PMID:20538976) RGD PMID:20538976 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Ppia peptidylprolyl isomerase A IDA RGD PMID:19832699 RGD:7247324 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:2,094,931...2,098,438
Ensembl chr20:2,094,931...2,098,433
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:11564868) RGD PMID:11564868 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B involved_in ISO (PMID:10807923) RGD PMID:10807923 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IDA
IMP
RGD PMID:12016225, PMID:10585469 RGD:625568, RGD:9999389 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:18715871)
RGD PMID:18715871, PMID:21873635 RGD:13792537 NCBI chr 6:127,400,585...127,497,280
Ensembl chr 6:127,400,585...127,497,280
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) RGD PMID:16916641 NCBI chr 3:8,982,122...9,012,585
Ensembl chr 3:8,982,122...9,012,585
JBrowse link
G Rgn regucalcin IMP RGD PMID:10922512 RGD:9590172 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO (PMID:24709986) RGD PMID:24709986 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO (PMID:17384681) RGD PMID:17384681 NCBI chr13:83,478,966...83,504,448
Ensembl chr13:83,478,974...83,504,494
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
ISO
GO_REF:0000107
(PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Mprip myosin phosphatase Rho interacting protein IMP RGD PMID:17661354 RGD:9685557 NCBI chr10:46,018,397...46,133,580
Ensembl chr10:46,018,659...46,133,571
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(PMID:16417406)
UniProt
RGD
PMID:16417406 GO_REF:0000024 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
UniProtKB:O75116 (PMID:25816133)
GO_REF:0000107
RGD
Ensembl
PMID:25816133 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D involved_in ISO
ISS
(PMID:12974676)
GO_REF:0000024
RGD
UniProt
PMID:12974676 GO_REF:0000024 NCBI chr 3:111,022,920...111,037,166
Ensembl chr 3:111,022,923...111,037,425
JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11500506 RGD:13508599 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:24846175) RGD PMID:24846175 NCBI chr13:43,850,744...44,157,860
Ensembl chr13:43,850,751...44,157,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of molecular function 3070
        regulation of catalytic activity 2372
          regulation of hydrolase activity 1077
            regulation of phosphatase activity 87
              negative regulation of phosphatase activity 39
                negative regulation of phosphoprotein phosphatase activity 26
                  negative regulation of myosin-light-chain-phosphatase activity 6
                  negative regulation of protein serine/threonine phosphatase activity 1
                  negative regulation of protein tyrosine phosphatase activity 2
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of metabolic process 6744
          regulation of cellular metabolic process 5950
            regulation of phosphorus metabolic process 1476
              regulation of phosphate metabolic process 1475
                regulation of dephosphorylation 134
                  regulation of protein dephosphorylation 94
                    regulation of phosphoprotein phosphatase activity 58
                      negative regulation of phosphoprotein phosphatase activity 26
                        negative regulation of myosin-light-chain-phosphatase activity 6
                        negative regulation of protein serine/threonine phosphatase activity 1
                        negative regulation of protein tyrosine phosphatase activity 2
paths to the root