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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of type I interferon production
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Accession:GO:0032479 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms:exact_synonym: regulation of type I IFN production



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regulation of type I interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO MGI:1328317 (MGI:5699498|PMID:26371324) RGD PMID:26371324 MGI:5699498 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Irf8 interferon regulatory factor 8 involved_in ISO (MGI:3654212|PMID:12461077) RGD PMID:12461077 MGI:3654212 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO
ISS
(PMID:27019227)
GO_REF:0000024
RGD
UniProt
PMID:27019227 GO_REF:0000024 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Rnf26 ring finger protein 26 involved_in ISO (PMID:25254379) RGD PMID:25254379 NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:25636800) RGD PMID:25636800 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:2442261|MGI:3052754 (MGI:4848004|PMID:20871604), (MGI:5523362|PMID:24154727), (MGI:5699498|PMID:26371324) RGD PMID:20871604 PMID:24154727 PMID:26371324 MGI:4848004 MGI:5523362 MGI:5699498 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
negative regulation of interferon-alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:26492563) RGD PMID:26492563 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:5568884 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nmi N-myc (and STAT) interactor acts_upstream_of_or_within ISO (MGI:5546557|PMID:23956435) RGD PMID:23956435 MGI:5546557 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISO (PMID:26231120) RGD PMID:26231120 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (MGI:5569198|PMID:24670807) RGD PMID:24670807 MGI:5569198 NCBI chr 9:76,677,403...76,688,035
Ensembl chr 9:76,677,404...76,687,986
JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829
JBrowse link
G Crebbp CREB binding protein involved_in ISO (MGI:2151262|PMID:11583620) RGD PMID:11583620 MGI:2151262 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (MGI:3828224|PMID:18851954) RGD PMID:18851954 MGI:3828224 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Mir26b microRNA 26b acts_upstream_of ISO (PMID:26222045) RGD PMID:26222045 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:5568884 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5141085 (MGI:5050761|PMID:21703540)
Ensembl
RGD
PMID:21703540 GO_REF:0000107 MGI:5050761 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484
JBrowse link
G Nmi N-myc (and STAT) interactor acts_upstream_of_or_within ISO (MGI:5546557|PMID:23956435) RGD PMID:23956435 MGI:5546557 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in ISS
ISO
GO_REF:0000024
(PMID:22750291)
UniProt
RGD
PMID:22750291 GO_REF:0000024 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISO (PMID:26231120) RGD PMID:26231120 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:19158675) RGD PMID:19158675 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit involved_in ISO (PMID:22065573) RGD PMID:22065573 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit involved_in ISO (PMID:22065573) RGD PMID:22065573 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO (MGI:5306204|PMID:22079989) RGD PMID:22079989 MGI:5306204 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977
JBrowse link
G Traip TRAF-interacting protein involved_in ISO (MGI:5619447|PMID:22945920) RGD PMID:22945920 MGI:5619447 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:16260628) RGD PMID:16260628 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
negative regulation of type I interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
JBrowse link
G Atg12 autophagy related 12 involved_in ISO (MGI:3722754|PMID:17709747) RGD PMID:17709747 MGI:3722754 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA
(MGI:3722754|PMID:17709747)
GO_REF:0000107
RGD
Ensembl
PMID:17709747 GO_REF:0000107 MGI:3722754 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Banf1 BAF nuclear assembly factor 1 involved_in ISO
ISS
(PMID:32792394)
GO_REF:0000024
RGD
UniProt
PMID:32792394 GO_REF:0000024 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188
JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:21525357)
(MGI:5318004|PMID:21525357)
RGD PMID:21525357 MGI:5318004 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Gpatch3 G patch domain containing 3 involved_in IBA
ISO
PMID:21873635
(PMID:28414768)
RGD PMID:28414768 PMID:21873635 RGD:13792537 NCBI chr 5:145,798,069...145,809,250
Ensembl chr 5:145,800,111...145,809,250
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains involved_in ISO (PMID:29802199) RGD PMID:29802199 NCBI chr20:5,809,931...5,876,231
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Nmi N-myc (and STAT) interactor acts_upstream_of_or_within ISO MGI:1859212 (MGI:5546557|PMID:23956435) RGD PMID:23956435 MGI:5546557 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO
IEA
ISS
(PMID:26471729)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO MGI:5441750 (MGI:5441107|PMID:23042151) RGD PMID:23042151 MGI:5441107 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857
JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO (PMID:17460044), (PMID:26471729) RGD PMID:17460044 PMID:26471729 NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:22079989)
Ensembl
RGD
PMID:22079989 GO_REF:0000107 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO
ISS
(PMID:26471729)
GO_REF:0000024
RGD
UniProt
PMID:26471729 GO_REF:0000024 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
JBrowse link
positive regulation of interferon-alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO (PMID:24784232)
(MGI:5583923|PMID:24784232)
RGD PMID:24784232 MGI:5583923 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Ddx58 DEXD/H-box helicase 58 involved_in ISO (PMID:19576794), (PMID:19609254), (PMID:21957149) RGD PMID:19576794 PMID:19609254 PMID:21957149 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:20696886) RGD PMID:20696886 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:3628823 (MGI:4452060|PMID:20457904) RGD PMID:20457904 MGI:4452060 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17164250)
(MGI:3708392|PMID:17164250)
PMID:21873635
RGD PMID:17164250 PMID:21873635 MGI:3708392, RGD:13792537 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO (PMID:19656871), (PMID:21957149) RGD PMID:19656871 PMID:21957149 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (MGI:4365354|PMID:18562536) RGD PMID:18562536 MGI:4365354 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:16127453), (PMID:19609254), (PMID:21957149)
MGI:6430641 (MGI:6370296|PMID:31390091)
GO_REF:0000024
RGD
UniProt
PMID:16127453 PMID:19609254 PMID:21957149 PMID:31390091 GO_REF:0000024 MGI:6370296 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO
GO_REF:0000107
(MGI:5583923|PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Nmb neuromedin B involved_in ISO (MGI:6435299|PMID:31601264) RGD PMID:31601264 MGI:6435299 NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
JBrowse link
G Nmbr neuromedin B receptor involved_in ISO
IEA
(PMID:31601264)
GO_REF:0000107
RGD
Ensembl
PMID:31601264 GO_REF:0000107 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:5562517 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:4456948|PMID:15356140)
Ensembl
RGD
PMID:15356140 GO_REF:0000107 MGI:4456948 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO (PMID:16286015)
(MGI:3042320|PMID:14976261)
RGD PMID:14976261 PMID:16286015 MGI:3042320 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 acts_upstream_of_or_within ISO MGI:5795738 (MGI:6370296|PMID:31390091) RGD PMID:31390091 MGI:6370296 NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,151...67,062,406
Ensembl chr 4:67,012,185...67,062,428
JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:27980081), (PMID:31575075) RGD PMID:27980081 PMID:31575075 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Ddx58 DEXD/H-box helicase 58 involved_in ISO
IBA
(PMID:17079289), (PMID:19211564), (PMID:19609254), (PMID:19631370), (PMID:21957149)
PMID:21873635
(MGI:5318026|PMID:17942531)
(PMID:17079289), (PMID:19609254), (PMID:19631370), (PMID:21957149)
RGD PMID:17079289 PMID:17942531 PMID:19211564 PMID:19609254 PMID:19631370 More... MGI:5318026, RGD:13792537 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hmgb2 high mobility group box 2 involved_in ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
ISS
(PMID:20628368)
GO_REF:0000024
RGD
UniProt
PMID:20628368 GO_REF:0000024 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in IBA
ISO
PMID:21873635
(PMID:17600090), (PMID:19211564), (PMID:19656871), (PMID:21957149), (PMID:33727702)
(PMID:17600090), (PMID:19656871), (PMID:21957149), (PMID:33727702)
RGD PMID:17600090 PMID:19211564 PMID:19656871 PMID:21957149 PMID:33727702 More... RGD:13792537 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 involved_in ISO (MGI:5619426|PMID:24598055) RGD PMID:24598055 MGI:5619426 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979
JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISO
ISS
(PMID:21389130)
GO_REF:0000024
RGD
UniProt
PMID:21389130 GO_REF:0000024 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (MGI:4365354|PMID:18562536) RGD PMID:18562536 MGI:4365354 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:22065573) RGD PMID:22065573 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:33727702) RGD PMID:33727702 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:16127453), (PMID:19609254), (PMID:19631370), (PMID:20628368), (PMID:21957149)
MGI:6430641 (MGI:6370296|PMID:31390091)
UniProt
RGD
PMID:16127453 PMID:19609254 PMID:19631370 PMID:20628368 PMID:21957149 More... GO_REF:0000024 MGI:6370296 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30822544) RGD PMID:30822544 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in ISO
IEA
(PMID:30822544)
GO_REF:0000107
RGD
Ensembl
PMID:30822544 GO_REF:0000107 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA
(PMID:30822544)
GO_REF:0000107
RGD
Ensembl
PMID:30822544 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
JBrowse link
G Polr3a RNA polymerase III subunit A involved_in ISO (PMID:19609254) RGD PMID:19609254 NCBI chr16:49,178...88,178
Ensembl chr16:49,521...88,172
JBrowse link
G Polr3b RNA polymerase III subunit B involved_in ISO (PMID:19609254) RGD PMID:19609254 NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598
JBrowse link
G Polr3c RNA polymerase III subunit C involved_in ISS
ISO
GO_REF:0000024
(PMID:19609254)
UniProt
RGD
PMID:19609254 GO_REF:0000024 NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208
JBrowse link
G Polr3d RNA polymerase III subunit D involved_in ISO (PMID:19631370) RGD PMID:19631370 NCBI chr15:45,511,587...45,516,256
Ensembl chr15:45,511,589...45,516,353
JBrowse link
G Polr3f RNA polymerase III subunit F involved_in ISO (PMID:19631370) RGD PMID:19631370 NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837
JBrowse link
G Polr3g RNA polymerase III subunit G involved_in ISO (PMID:19609254), (PMID:19631370) RGD PMID:19609254 PMID:19631370 NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:5562517 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:24807708) RGD PMID:24807708 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
JBrowse link
G Rnf135 ring finger protein 135 involved_in ISS
ISO
GO_REF:0000024
(PMID:19017631)
UniProt
RGD
PMID:19017631 GO_REF:0000024 NCBI chr10:65,170,560...65,189,791
Ensembl chr10:65,170,560...65,262,804
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19433799), (PMID:21074459), (PMID:25254379)
(MGI:3849536|PMID:19433799), (MGI:4365649|PMID:19776740)
UniProt
RGD
PMID:19433799 PMID:19776740 PMID:21074459 PMID:25254379 GO_REF:0000024 MGI:3849536 MGI:4365649 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:16127453)
MGI:3046789 (MGI:3530402|PMID:15661922)
RGD PMID:15661922 PMID:16127453 MGI:3530402 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794|MGI:3029019 (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135) RGD PMID:12855817 PMID:12872135 MGI:2669022 MGI:2670551 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (MGI:4456948|PMID:15356140) RGD PMID:15356140 MGI:4456948 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:12054664), (PMID:16286015)
(MGI:4456948|PMID:15356140)
RGD PMID:12054664 PMID:15356140 PMID:16286015 MGI:4456948 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4456948|PMID:15356140)
MGI:1860885 (MGI:3530402|PMID:15661922)
Ensembl
RGD
PMID:15356140 PMID:15661922 GO_REF:0000107 MGI:3530402 MGI:4456948 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:16286015)
(MGI:4456948|PMID:15356140)
RGD PMID:15356140 PMID:16286015 MGI:4456948 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in ISO
IEA
ISS
(PMID:20628368)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 acts_upstream_of_or_within ISO MGI:5795738 (MGI:6370296|PMID:31390091) RGD PMID:31390091 MGI:6370296 NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673
JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (MGI:4849871|PMID:21074459) RGD PMID:21074459 MGI:4849871 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 involved_in ISO (MGI:5619432|PMID:23776228) RGD PMID:23776228 MGI:5619432 NCBI chr11:57,052,129...57,823,679
Ensembl chr11:57,072,880...57,510,210
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,151...67,062,406
Ensembl chr 4:67,012,185...67,062,428
JBrowse link
positive regulation of type I interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in IBA
ISO
PMID:21873635
(MGI:5300392|PMID:22078883)
RGD PMID:22078883 PMID:21873635 MGI:5300392, RGD:13792537 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in IBA
ISO
PMID:21873635
(PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:28738408), (PMID:32792394), (PMID:33230297), (PMID:33406424)
(MGI:5908326|PMID:24077100), (MGI:5909141|PMID:28759889), (MGI:5909142|PMID:28759028)
RGD PMID:24077100 PMID:26046437 PMID:28363908 PMID:28738408 PMID:28759028 More... MGI:5908326 MGI:5909141 MGI:5909142, RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (MGI:6120210|PMID:24037184) RGD PMID:24037184 MGI:6120210 NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567
JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (MGI:4421606|PMID:20080593) RGD PMID:20080593 MGI:4421606 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 involved_in ISO (PMID:30510222), (PMID:30804210) RGD PMID:30510222 PMID:30804210 NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISS
ISO
GO_REF:0000024
(PMID:27387501)
UniProt
RGD
PMID:27387501 GO_REF:0000024 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Garin5a golgi associated RAB2 interactor 5A involved_in ISO (MGI:6709519|PMID:28930687) RGD PMID:28930687 MGI:6709519 NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3691368|PMID:17018642)
UniProt
RGD
PMID:17018642 GO_REF:0000024 MGI:3691368 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:25636800) RGD PMID:25636800 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:32433612) RGD PMID:32433612 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within ISO MGI:1928368 (MGI:5546557|PMID:23956435) RGD PMID:23956435 MGI:5546557 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Mavs mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO MGI:3654145 (MGI:3807296|PMID:18780793) RGD PMID:18780793 MGI:3807296 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5300392|PMID:22078883)
Ensembl
RGD
PMID:22078883 GO_REF:0000107 MGI:5300392 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:26046437)
UniProt
RGD
PMID:26046437 GO_REF:0000024 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Rab2b RAB2B, member RAS oncogene family involved_in ISO (MGI:6709519|PMID:28930687) RGD PMID:28930687 MGI:6709519 NCBI chr15:24,968,364...24,988,990
Ensembl chr15:24,968,803...24,989,113
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IBA
ISO
IDA
PMID:21873635
(MGI:5787716|PMID:26669264), (MGI:5881983|PMID:27324217), (MGI:6195680|PMID:29973723)
(PMID:22394562), (PMID:23747010), (PMID:26669264), (PMID:29694889), (PMID:29973723), (PMID:30842659)
(PMID:22394562), (PMID:23747010), (PMID:26669264), (PMID:29694889), (PMID:30842659)
RGD PMID:22394562 PMID:23747010 PMID:26669264 PMID:27324217 PMID:29694889 More... MGI:5787716 MGI:5881983 MGI:6195680, RGD:13792537, RGD:11344949 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO
GO_REF:0000107
(MGI:5300392|PMID:22078883)
Ensembl
RGD
PMID:22078883 GO_REF:0000107 MGI:5300392 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794 (MGI:2670551|PMID:12872135) RGD PMID:12872135 MGI:2670551 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (MGI:3774796|PMID:18207576) RGD PMID:18207576 MGI:3774796 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:4868308|PMID:21102435)
PMID:21873635
RGD PMID:21102435 PMID:21873635 MGI:4868308, RGD:13792537 NCBI chr 4:67,012,151...67,062,406
Ensembl chr 4:67,012,185...67,062,428
JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA
(MGI:6209107|PMID:30135424)
PMID:21873635
RGD PMID:30135424 PMID:21873635 MGI:6209107, RGD:13792537 NCBI chr 3:140,872,460...140,875,851
Ensembl chr 3:140,872,460...140,882,408
JBrowse link
regulation of interferon-beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf216 ring finger protein 216 involved_in ISO (PMID:19893624) RGD PMID:19893624 NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (MGI:4942245|PMID:14630816) RGD PMID:14630816 MGI:4942245 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO (MGI:4839450|PMID:16306937) RGD PMID:16306937 MGI:4839450 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Trim38 tripartite motif containing 38 acts_upstream_of_or_within ISO (MGI:5441682|PMID:22539786) RGD PMID:22539786 MGI:5441682 NCBI chr17:41,351,857...41,365,021 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    regulation of biological process 13160
      regulation of multicellular organismal process 3162
        regulation of cytokine production 857
          regulation of type I interferon production 102
            negative regulation of type I interferon production + 30
            positive regulation of type I interferon production + 66
            regulation of interferon-alpha production + 30
            regulation of interferon-beta production + 62
Path 2
Term Annotations click to browse term
  biological_process 20099
    metabolic process 12353
      organic substance metabolic process 11873
        macromolecule metabolic process 10218
          gene expression 6704
            cytokine production 864
              regulation of cytokine production 857
                regulation of type I interferon production 102
                  negative regulation of type I interferon production + 30
                  positive regulation of type I interferon production + 66
                  regulation of interferon-alpha production + 30
                  regulation of interferon-beta production + 62
paths to the root