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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K9 demethylase activity
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Accession:GO:0032454 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein.
Synonyms:exact_synonym: histone H3-K49 demethylase activity;   histone H3-methyl-lysine-9 demethylase activity;   histone demethylase activity (H3-K9 specific)
 xref: reactome:R-HSA-9011949 "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers";   reactome:R-HSA-9011985 "KDM1A demethylates H3 on MYC and BCL genes in response to estrogen";   reactome:R-HSA-997263 "JMJD1C demethylates H3K9 mono- and di-methylation"


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histone H3K9 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr HR, lysine demethylase and nuclear receptor corepressor enables IEA
IBA		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033		 InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313 		JBrowse link
G Jmjd1c jumonji domain containing 1C enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122 		JBrowse link
G Kdm1a lysine demethylase 1A enables ISO (PMID:16079795), (PMID:20228790) RGD PMID:16079795 PMID:20228790 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm3a lysine demethylase 3A enables ISO
IBA
IEA		 (PMID:28262558)
MGI:3764891 (PMID:17938240), (PMID:17943087), (PMID:17991879)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000002		 RGD
GO_Central
TreeGrafter
InterPro		 PMID:17938240 PMID:17943087 PMID:17991879 PMID:28262558 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdm3b lysine demethylase 3B enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628 		JBrowse link
G Kdm4a lysine demethylase 4A enables IBA
ISO		 GO_REF:0000033
(PMID:16738407)		 GO_Central
RGD		 PMID:16738407 GO_REF:0000033 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B enables ISO
IBA		 (PMID:28262558)
(PMID:16738407)
GO_REF:0000033		 RGD
GO_Central		 PMID:16738407 PMID:28262558 GO_REF:0000033 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm4c lysine demethylase 4C enables ISO
IBA		 (PMID:18066052), (PMID:28262558)
(PMID:16738407), (PMID:17938240)
GO_REF:0000033		 RGD
GO_Central		 PMID:16738407 PMID:17938240 PMID:18066052 PMID:28262558 GO_REF:0000033 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Kdm4d lysine demethylase 4D enables ISO
IBA		 (PMID:25124442)
MGI:5051955 (PMID:16738407), (PMID:21293030), (PMID:24550317)
GO_REF:0000033		 RGD
GO_Central		 PMID:16738407 PMID:21293030 PMID:24550317 PMID:25124442 GO_REF:0000033 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G Kdm7a lysine demethylase 7A enables ISO (PMID:20023638), (PMID:20194436), (PMID:20622853)
(MGI:4437342|PMID:20194436)		 RGD PMID:20023638 PMID:20194436 PMID:20622853 MGI:4437342 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Phf2 PHD finger protein 2 enables ISO (PMID:21532585) RGD PMID:21532585 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO (PMID:20023638), (PMID:20208542), (PMID:20346720), (PMID:20622853), (PMID:20622854) RGD PMID:20023638 PMID:20208542 PMID:20346720 PMID:20622853 PMID:20622854 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
histone H3K9me/H3K9me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr HR, lysine demethylase and nuclear receptor corepressor enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313 		JBrowse link
G Kdm3a lysine demethylase 3A enables ISO
IEA		 (PMID:16603237)
GO_REF:0000107		 RGD
Ensembl		 PMID:16603237 GO_REF:0000107 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
histone H3K9me2/H3K9me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO (MGI:4838688|PMID:20833138) RGD PMID:20833138 MGI:4838688 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm4a lysine demethylase 4A enables ISO (PMID:21914792) RGD PMID:21914792 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B enables ISO (PMID:21914792) RGD PMID:21914792 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm4c lysine demethylase 4C enables
contributes_to		 ISO (PMID:21914792)
(PMID:17277772)		 RGD PMID:17277772 PMID:21914792 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Kdm4d lysine demethylase 4D enables ISO (PMID:21914792) RGD PMID:21914792 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      demethylase activity 45
        protein demethylase activity 33
          histone demethylase activity 33
            histone H3 demethylase activity 29
              histone H3K9 demethylase activity 12
                FAD-dependent histone H3K9me/H3K9me2 demethylase activity 0
                histone H3K9me/H3K9me2 demethylase activity 2
                histone H3K9me2/H3K9me3 demethylase activity 5
paths to the root