ONTOLOGY REPORT - ANNOTATIONS |
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Term: | demethylase activity |
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Accession: | GO:0032451
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browse the term
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Definition: | Catalysis of the removal of a methyl group from a substrate. |
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GViewer not supported for the selected species.
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Alkbh4 |
alkB homolog 4, lysine demethylase |
enables |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chrNW_004936543:1,883,353...1,889,159
Ensembl chrNW_004936543:1,883,321...1,889,155
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Kdm1a |
lysine demethylase 1A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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LOC101969148 |
cytochrome P450 1A1 |
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ISO |
N-demethylation of benzphetamine, aminopyrine N-demethylation of amitriptyline, erythromycin, diazapam, imipramine, lidocaine, morphine |
RGD |
PMID:10915793 PMID:11370669 |
RGD:2306679 RGD:2306680 |
NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
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LOC101969421 |
cytochrome P450 1A2 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484
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Mmachc |
metabolism of cobalamin associated C |
enables |
IEA |
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TreeGrafter Ensembl |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936474:26,636,277...26,641,486
Ensembl chrNW_004936474:26,636,245...26,641,486
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Alkbh1 |
alkB homolog 1, histone H2A dioxygenase |
enables |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chrNW_004936488:6,459,195...6,486,756
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Alkbh2 |
alkB homolog 2, alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936769:904,129...908,130
Ensembl chrNW_004936769:904,125...906,881
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Alkbh3 |
alkB homolog 3, alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936562:4,743,595...4,777,685
Ensembl chrNW_004936562:4,741,371...4,777,727
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Alkbh4 |
alkB homolog 4, lysine demethylase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936543:1,883,353...1,889,159
Ensembl chrNW_004936543:1,883,321...1,889,155
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Fto |
FTO alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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TreeGrafter InterPro Ensembl |
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GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588
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Alkbh2 |
alkB homolog 2, alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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TreeGrafter Ensembl |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936769:904,129...908,130
Ensembl chrNW_004936769:904,125...906,881
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Alkbh3 |
alkB homolog 3, alpha-ketoglutarate dependent dioxygenase |
enables |
ISO |
(PMID:16174769) |
MGI |
PMID:16174769 |
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NCBI chrNW_004936562:4,743,595...4,777,685
Ensembl chrNW_004936562:4,741,371...4,777,727
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Kdm1a |
lysine demethylase 1A |
enables |
IEA |
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UniProt RHEA Ensembl |
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GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 |
NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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Kdm1b |
lysine demethylase 1B |
enables |
IEA |
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Ensembl UniProt |
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GO_REF:0000107 GO_REF:0000117 |
NCBI chrNW_004936552:3,921,217...3,964,281
Ensembl chrNW_004936552:3,921,490...3,962,648
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Jarid2 |
jumonji and AT-rich interaction domain containing 2 |
NOT|enables |
ISO |
(PMID:20064376) |
UniProt |
PMID:20064376 |
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NCBI chrNW_004936552:1,566,382...1,786,837
Ensembl chrNW_004936552:1,566,788...1,785,490
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Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936594:1,760,924...1,771,022
Ensembl chrNW_004936594:1,760,853...1,770,765
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Kdm1a |
lysine demethylase 1A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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Kdm4a |
lysine demethylase 4A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936474:25,002,527...25,056,642
Ensembl chrNW_004936474:25,002,509...25,056,642
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Kdm4b |
lysine demethylase 4B |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936588:2,908,970...3,005,625
Ensembl chrNW_004936588:2,908,899...3,005,674
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Kdm4c |
lysine demethylase 4C |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082
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Kdm6a |
lysine demethylase 6A |
enables |
IEA |
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UniProt |
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GO_REF:0000117 |
NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163
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Kdm6b |
lysine demethylase 6B |
enables |
IEA |
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UniProt |
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GO_REF:0000117 |
NCBI chrNW_004936595:1,077,318...1,099,082
Ensembl chrNW_004936595:1,089,544...1,097,595
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LOC101967900 |
lysine-specific demethylase 4D |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936674:53,200...73,042
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Phf2 |
PHD finger protein 2 |
NOT|enables |
ISO |
(PMID:21167174) |
UniProt |
PMID:21167174 |
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NCBI chrNW_004936487:2,912,114...2,956,429
Ensembl chrNW_004936487:2,912,112...2,954,525
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Phf8 |
PHD finger protein 8 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936751:850,630...935,382
Ensembl chrNW_004936751:850,237...934,586
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Kdm6a |
lysine demethylase 6A |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163
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Kdm6b |
lysine demethylase 6B |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936595:1,077,318...1,099,082
Ensembl chrNW_004936595:1,089,544...1,097,595
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Kdm7a |
lysine demethylase 7A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936592:4,250,658...4,305,838
Ensembl chrNW_004936592:4,257,113...4,298,903
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Phf8 |
PHD finger protein 8 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936751:850,630...935,382
Ensembl chrNW_004936751:850,237...934,586
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Kdm2a |
lysine demethylase 2A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936599:2,466,427...2,576,623
Ensembl chrNW_004936599:2,466,214...2,576,623
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Kdm2b |
lysine demethylase 2B |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936558:2,771,420...2,897,694
Ensembl chrNW_004936558:2,771,420...2,897,292
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Kdm4a |
lysine demethylase 4A |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936474:25,002,527...25,056,642
Ensembl chrNW_004936474:25,002,509...25,056,642
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Kdm4b |
lysine demethylase 4B |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936588:2,908,970...3,005,625
Ensembl chrNW_004936588:2,908,899...3,005,674
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Kdm4c |
lysine demethylase 4C |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082
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Kdm7a |
lysine demethylase 7A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936592:4,250,658...4,305,838
Ensembl chrNW_004936592:4,257,113...4,298,903
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Kdm8 |
lysine demethylase 8 |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936501:10,932,541...10,955,772
Ensembl chrNW_004936501:10,933,671...10,951,707
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Phf8 |
PHD finger protein 8 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936751:850,630...935,382
Ensembl chrNW_004936751:850,237...934,586
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Riox1 |
ribosomal oxygenase 1 |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936488:2,766,406...2,768,551
Ensembl chrNW_004936488:2,766,451...2,768,408
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Riox2 |
ribosomal oxygenase 2 |
enables |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chrNW_004936666:3,226,800...3,262,193
Ensembl chrNW_004936666:3,229,174...3,262,193
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Kdm2b |
lysine demethylase 2B |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chrNW_004936558:2,771,420...2,897,694
Ensembl chrNW_004936558:2,771,420...2,897,292
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Riox1 |
ribosomal oxygenase 1 |
enables |
IEA |
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UniProt RHEA |
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GO_REF:0000003 GO_REF:0000116 |
NCBI chrNW_004936488:2,766,406...2,768,551
Ensembl chrNW_004936488:2,766,451...2,768,408
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Kdm1a |
lysine demethylase 1A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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Kdm1b |
lysine demethylase 1B |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936552:3,921,217...3,964,281
Ensembl chrNW_004936552:3,921,490...3,962,648
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Kdm5a |
lysine demethylase 5A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936606:486,424...570,546
Ensembl chrNW_004936606:485,655...570,739
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Kdm5b |
lysine demethylase 5B |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936567:1,782,056...1,860,861
Ensembl chrNW_004936567:1,781,995...1,863,461
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Kdm5c |
lysine demethylase 5C |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966
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Riox1 |
ribosomal oxygenase 1 |
enables |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chrNW_004936488:2,766,406...2,768,551
Ensembl chrNW_004936488:2,766,451...2,768,408
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Riox2 |
ribosomal oxygenase 2 |
enables |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chrNW_004936666:3,226,800...3,262,193
Ensembl chrNW_004936666:3,229,174...3,262,193
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Kdm1b |
lysine demethylase 1B |
NOT|enables |
ISO |
(PMID:19407342), (PMID:19727073) |
UniProt |
PMID:19407342 PMID:19727073 |
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NCBI chrNW_004936552:3,921,217...3,964,281
Ensembl chrNW_004936552:3,921,490...3,962,648
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Kdm5a |
lysine demethylase 5A |
enables |
IEA |
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UniProt TreeGrafter Ensembl |
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GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936606:486,424...570,546
Ensembl chrNW_004936606:485,655...570,739
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Kdm5b |
lysine demethylase 5B |
enables |
IEA |
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TreeGrafter Ensembl UniProt |
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GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936567:1,782,056...1,860,861
Ensembl chrNW_004936567:1,781,995...1,863,461
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Kdm5c |
lysine demethylase 5C |
enables |
IEA |
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UniProt TreeGrafter |
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GO_REF:0000003 GO_REF:0000118 |
NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966
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Riox1 |
ribosomal oxygenase 1 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936488:2,766,406...2,768,551
Ensembl chrNW_004936488:2,766,451...2,768,408
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Hr |
HR lysine demethylase and nuclear receptor corepressor |
enables |
IEA |
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InterPro TreeGrafter |
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GO_REF:0000002 GO_REF:0000118 |
NCBI chrNW_004936555:5,936,431...5,954,852
Ensembl chrNW_004936555:5,936,220...5,954,974
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Jmjd1c |
jumonji domain containing 1C |
enables |
IEA |
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InterPro TreeGrafter |
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GO_REF:0000002 GO_REF:0000118 |
NCBI chrNW_004936753:1,413,935...1,645,974
Ensembl chrNW_004936753:1,414,240...1,645,161
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Kdm1a |
lysine demethylase 1A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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Kdm3a |
lysine demethylase 3A |
enables |
IEA |
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InterPro TreeGrafter Ensembl |
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GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936712:1,053,210...1,097,845
Ensembl chrNW_004936712:1,053,210...1,096,961
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Kdm3b |
lysine demethylase 3B |
enables |
IEA |
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InterPro TreeGrafter |
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GO_REF:0000002 GO_REF:0000118 |
NCBI chrNW_004936531:7,517,810...7,600,319
Ensembl chrNW_004936531:7,516,125...7,600,347
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Kdm4a |
lysine demethylase 4A |
enables |
IEA |
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Ensembl TreeGrafter UniProt |
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GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 |
NCBI chrNW_004936474:25,002,527...25,056,642
Ensembl chrNW_004936474:25,002,509...25,056,642
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G |
Kdm4b |
lysine demethylase 4B |
enables |
IEA |
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Ensembl UniProt TreeGrafter |
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GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 |
NCBI chrNW_004936588:2,908,970...3,005,625
Ensembl chrNW_004936588:2,908,899...3,005,674
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G |
Kdm4c |
lysine demethylase 4C |
enables |
IEA |
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Ensembl UniProt TreeGrafter |
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GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 |
NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082
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G |
Kdm7a |
lysine demethylase 7A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936592:4,250,658...4,305,838
Ensembl chrNW_004936592:4,257,113...4,298,903
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G |
LOC101967900 |
lysine-specific demethylase 4D |
enables |
IEA |
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TreeGrafter Ensembl |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936674:53,200...73,042
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G |
Phf2 |
PHD finger protein 2 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936487:2,912,114...2,956,429
Ensembl chrNW_004936487:2,912,112...2,954,525
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G |
Phf8 |
PHD finger protein 8 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936751:850,630...935,382
Ensembl chrNW_004936751:850,237...934,586
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G |
Kdm3a |
lysine demethylase 3A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936712:1,053,210...1,097,845
Ensembl chrNW_004936712:1,053,210...1,096,961
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Kdm1a |
lysine demethylase 1A |
enables |
ISO |
(PMID:20833138) |
BHF-UCL |
PMID:20833138 |
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NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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G |
Kdm4a |
lysine demethylase 4A |
enables |
IEA |
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UniProt Ensembl |
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GO_REF:0000003 GO_REF:0000107 |
NCBI chrNW_004936474:25,002,527...25,056,642
Ensembl chrNW_004936474:25,002,509...25,056,642
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G |
Kdm4b |
lysine demethylase 4B |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chrNW_004936588:2,908,970...3,005,625
Ensembl chrNW_004936588:2,908,899...3,005,674
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G |
Kdm4c |
lysine demethylase 4C |
enables |
IEA |
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UniProt Ensembl |
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GO_REF:0000003 GO_REF:0000107 |
NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082
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G |
LOC101967900 |
lysine-specific demethylase 4D |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936674:53,200...73,042
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G |
Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936594:1,760,924...1,771,022
Ensembl chrNW_004936594:1,760,853...1,770,765
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G |
Kdm7a |
lysine demethylase 7A |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936592:4,250,658...4,305,838
Ensembl chrNW_004936592:4,257,113...4,298,903
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G |
Phf2 |
PHD finger protein 2 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936487:2,912,114...2,956,429
Ensembl chrNW_004936487:2,912,112...2,954,525
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G |
Phf8 |
PHD finger protein 8 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936751:850,630...935,382
Ensembl chrNW_004936751:850,237...934,586
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Rsbn1 |
round spermatid basic protein 1 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936690:2,130,226...2,178,796
Ensembl chrNW_004936690:2,130,206...2,178,737
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Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
enables |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936594:1,760,924...1,771,022
Ensembl chrNW_004936594:1,760,853...1,770,765
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Alkbh3 |
alkB homolog 3, alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936562:4,743,595...4,777,685
Ensembl chrNW_004936562:4,741,371...4,777,727
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Alkbh5 |
alkB homolog 5, RNA demethylase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936741:1,729,707...1,756,108
Ensembl chrNW_004936741:1,729,679...1,757,419
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Fto |
FTO alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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TreeGrafter Ensembl UniProt |
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GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 |
NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588
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Alkbh1 |
alkB homolog 1, histone H2A dioxygenase |
enables |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chrNW_004936488:6,459,195...6,486,756
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Alkbh3 |
alkB homolog 3, alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936562:4,743,595...4,777,685
Ensembl chrNW_004936562:4,741,371...4,777,727
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Alkbh5 |
alkB homolog 5, RNA demethylase |
enables |
IEA |
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TreeGrafter InterPro |
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GO_REF:0000002 GO_REF:0000118 |
NCBI chrNW_004936741:1,729,707...1,756,108
Ensembl chrNW_004936741:1,729,679...1,757,419
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Fto |
FTO alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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InterPro Ensembl |
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GO_REF:0000002 GO_REF:0000107 |
NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588
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G |
Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936594:1,760,924...1,771,022
Ensembl chrNW_004936594:1,760,853...1,770,765
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G |
Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936594:1,760,924...1,771,022
Ensembl chrNW_004936594:1,760,853...1,770,765
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Riox1 |
ribosomal oxygenase 1 |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936488:2,766,406...2,768,551
Ensembl chrNW_004936488:2,766,451...2,768,408
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LOC101955024 |
lanosterol 14-alpha demethylase |
enables |
ISO IEA |
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RGD Ensembl |
PMID:7581240 PMID:7665087 |
GO_REF:0000107 RGD:1298863 RGD:2316902 |
NCBI chrNW_004936621:2,209,255...2,232,404
Ensembl chrNW_004936621:2,209,199...2,232,531
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Alkbh1 |
alkB homolog 1, histone H2A dioxygenase |
enables |
ISO |
(PMID:27745969) |
UniProt |
PMID:27745969 |
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NCBI chrNW_004936488:6,459,195...6,486,756
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G |
Fto |
FTO alpha-ketoglutarate dependent dioxygenase |
enables |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588
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Term paths to the root
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