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ONTOLOGY REPORT - ANNOTATIONS

Term:demethylase activity
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Accession:GO:0032451 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a substrate.


show annotations for term's descendants           Sort by:
demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh4 alkB homolog 4, lysine demethylase enables IBA GO_Central GO_REF:0000033 NCBI chr 5:136,164,999...136,170,654
Ensembl chr 5:136,165,000...136,170,469 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 enables ISO
IEA		 N-demethylation of amitriptyline, erythromycin, diazapam, imipramine, lidocaine, morphine
N-demethylation of benzphetamine, aminopyrine		 RGD
Ensembl
GO_Central		 PMID:10915793 PMID:11370669 GO_REF:0000096 GO_REF:0000107 RGD:2306679 RGD:2306680 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 enables ISO GO_Central GO_REF:0000096 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 enables ISO GO_Central GO_REF:0000096 NCBI chr 5:145,373,119...145,406,550
Ensembl chr 5:145,373,119...145,406,533 		JBrowse link
G Cyp3a41a cytochrome P450, family 3, subfamily a, polypeptide 41A enables ISO GO_Central GO_REF:0000096 NCBI chr 5:145,630,859...145,656,946
Ensembl chr 5:145,630,859...145,656,946 		JBrowse link
G Cyp3a41b cytochrome P450, family 3, subfamily a, polypeptide 41B enables ISO GO_Central GO_REF:0000096 NCBI chr 5:145,495,474...145,521,542
Ensembl chr 5:145,495,474...145,521,540 		JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 enables ISO GO_Central GO_REF:0000096 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A enables ISO GO_Central GO_REF:0000119 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Mmachc methylmalonic aciduria cblC type, with homocystinuria enables IBA
ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:116,559,631...116,565,582
Ensembl chr 4:116,559,476...116,565,603 		JBrowse link
broad specificity oxidative DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables ISO
IBA
ISS
IDA		 (PMID:27027282) GO_Central
UniProt		 PMID:27027282 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr12:87,474,847...87,490,609
Ensembl chr12:87,472,610...87,490,787 		JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase enables ISO
IBA
IMP
IDA
ISS		 (PMID:18519673)
(PMID:16174769)		 GO_Central
UniProt		 PMID:16174769 PMID:18519673 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:114,261,987...114,268,782
Ensembl chr 5:114,261,987...114,266,279 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables IDA
ISS
ISO		 (PMID:16174769) UniProt
GO_Central		 PMID:16174769 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152 		JBrowse link
G Alkbh4 alkB homolog 4, lysine demethylase enables IDA (PMID:30982744) UniProt PMID:30982744 NCBI chr 5:136,164,999...136,170,654
Ensembl chr 5:136,165,000...136,170,469 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase enables IBA
IDA
ISO		 (PMID:18775698) GO_Central
BHF-UCL		 PMID:18775698 GO_REF:0000033 GO_REF:0000119 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
cytosine C-5 DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase enables IDA
IBA
ISS
ISO		 (PMID:16174769) MGI
GO_Central
UniProt		 PMID:16174769 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:114,261,987...114,268,782
Ensembl chr 5:114,261,987...114,266,279 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables IDA (PMID:16174769) MGI PMID:16174769 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152 		JBrowse link
DNA N6-methyladenine demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr12:87,474,847...87,490,609
Ensembl chr12:87,472,610...87,490,787 		JBrowse link
G Alkbh4 alkB homolog 4, lysine demethylase enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 5:136,164,999...136,170,654
Ensembl chr 5:136,165,000...136,170,469 		JBrowse link
FAD-dependent H3K4me/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine (K)-specific demethylase 1A enables IDA
IBA
IEA
ISO
ISS		 (PMID:24843136) MGI
GO_Central
UniProt
RHEA		 PMID:24843136 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117 GO_REF:0000119 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm1b lysine (K)-specific demethylase 1B enables IDA
ISO		 (PMID:19407342), (PMID:19727073) MGI
GO_Central		 PMID:19407342 PMID:19727073 GO_REF:0000119 NCBI chr13:47,196,849...47,238,085
Ensembl chr13:47,196,975...47,238,755 		JBrowse link
FAD-dependent histone H3K9me/H3K9me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr lysine demethylase and nuclear receptor corepressor enables IEA UniProt GO_REF:0000003 NCBI chr14:70,789,644...70,810,988
Ensembl chr14:70,789,652...70,810,988 		JBrowse link
G Kdm3a lysine (K)-specific demethylase 3A enables IEA UniProt GO_REF:0000003 NCBI chr 6:71,565,954...71,609,963
Ensembl chr 6:71,565,956...71,609,974 		JBrowse link
G Kdm3b KDM3B lysine (K)-specific demethylase 3B enables IEA UniProt GO_REF:0000003 NCBI chr18:34,910,061...34,972,423
Ensembl chr18:34,910,100...34,971,713 		JBrowse link
G Phf8 PHD finger protein 8 enables IEA UniProt GO_REF:0000003 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
histone demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxl19 F-box and leucine-rich repeat protein 19 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:127,343,059...127,368,655
Ensembl chr 7:127,343,715...127,368,655 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 NOT|enables IBA
IDA		 (PMID:20064376) GO_Central
UniProt		 PMID:20064376 GO_REF:0000033 NCBI chr13:44,881,817...45,075,119
Ensembl chr13:44,882,950...45,075,119 		JBrowse link
G Jmjd6 jumonji domain containing 6 enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A enables ISO
ISS		 GO_Central
BHF-UCL		 GO_REF:0000024 GO_REF:0000119 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm2a lysine (K)-specific demethylase 2A enables IBA GO_Central GO_REF:0000033 NCBI chr19:4,366,172...4,448,749
Ensembl chr19:4,364,447...4,448,313 		JBrowse link
G Kdm2b lysine (K)-specific demethylase 2B enables TAS
IBA		 (PMID:21220025) BHF-UCL
GO_Central		 PMID:21220025 GO_REF:0000033 NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886 		JBrowse link
G Kdm4a lysine (K)-specific demethylase 4A enables IDA (PMID:19144645) MGI PMID:19144645 NCBI chr 4:117,994,154...118,037,216
Ensembl chr 4:117,994,154...118,037,240 		JBrowse link
G Kdm4b lysine (K)-specific demethylase 4B enables IDA (PMID:19144645) MGI PMID:19144645 NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870 		JBrowse link
G Kdm4c lysine (K)-specific demethylase 4C enables IDA
ISO		 (PMID:19144645) MGI
GO_Central		 PMID:19144645 GO_REF:0000119 NCBI chr 4:74,160,734...74,324,101
Ensembl chr 4:74,160,734...74,324,097 		JBrowse link
G Kdm4d lysine (K)-specific demethylase 4D enables IDA (PMID:19144645) MGI PMID:19144645 NCBI chr 9:14,373,844...14,411,818
Ensembl chr 9:14,373,844...14,411,778 		JBrowse link
G Kdm4dl lysine (K)-specific demethylase 4D-like enables IDA (PMID:23451023) MGI PMID:23451023 NCBI chr 9:14,362,311...14,363,318
Ensembl chr 9:14,362,132...14,363,318 		JBrowse link
G Kdm7a lysine (K)-specific demethylase 7A enables IBA GO_Central GO_REF:0000033 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723 		JBrowse link
G Phf2 PHD finger protein 2 NOT|enables ISO
IBA		 (PMID:21167174) UniProt
GO_Central		 PMID:21167174 GO_REF:0000033 NCBI chr13:48,955,226...49,024,361
Ensembl chr13:48,955,226...49,024,595 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO
IBA
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
histone H3K27me2/H3K27me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm6a lysine (K)-specific demethylase 6A enables IDA
IBA		 (PMID:22949634) MGI
GO_Central		 PMID:22949634 GO_REF:0000033 NCBI chr  X:18,027,101...18,147,061
Ensembl chr  X:18,028,814...18,146,175 		JBrowse link
G Kdm6b KDM1 lysine (K)-specific demethylase 6B enables IMP
IBA
IDA
ISO		 (PMID:17928865), (PMID:18716661)
(PMID:23856522)		 MGI
GO_Central
BHF-UCL		 PMID:17928865 PMID:18716661 PMID:23856522 GO_REF:0000033 GO_REF:0000119 NCBI chr11:69,289,334...69,311,188
Ensembl chr11:69,289,334...69,304,501 		JBrowse link
G Kdm7a lysine (K)-specific demethylase 7A enables ISO
IMP		 (PMID:20194436) GO_Central
UniProt		 PMID:20194436 GO_REF:0000119 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723 		JBrowse link
G Phf8 PHD finger protein 8 enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables IEA
IBA		 RHEA
GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  Y:1,085,187...1,245,787
Ensembl chr  Y:1,096,861...1,245,759 		JBrowse link
histone H3K36 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm2a lysine (K)-specific demethylase 2A enables ISO MGI GO_REF:0000008 GO_REF:0000119 NCBI chr19:4,366,172...4,448,749
Ensembl chr19:4,364,447...4,448,313 		JBrowse link
G Kdm2b lysine (K)-specific demethylase 2B enables IDA
ISS
ISO		 (PMID:21540074) MGI
UniProt
GO_Central		 PMID:21540074 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886 		JBrowse link
G Kdm4a lysine (K)-specific demethylase 4A enables ISO
IBA		 GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr 4:117,994,154...118,037,216
Ensembl chr 4:117,994,154...118,037,240 		JBrowse link
G Kdm4b lysine (K)-specific demethylase 4B enables IMP
ISO
IDA		 (PMID:16738407) MGI
GO_Central		 PMID:16738407 GO_REF:0000119 NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870 		JBrowse link
G Kdm4c lysine (K)-specific demethylase 4C enables IEA
IBA
ISO		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:74,160,734...74,324,101
Ensembl chr 4:74,160,734...74,324,097 		JBrowse link
G Kdm7a lysine (K)-specific demethylase 7A enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723 		JBrowse link
G Kdm8 lysine (K)-specific demethylase 8 enables IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 7:125,043,788...125,062,823
Ensembl chr 7:125,043,848...125,061,441 		JBrowse link
G Phf8 PHD finger protein 8 enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IBA
IDA		 (PMID:19927124) GO_Central
UniProt		 PMID:19927124 GO_REF:0000033 NCBI chr12:83,997,382...83,999,727
Ensembl chr12:83,997,382...83,999,725 		JBrowse link
G Riox2 ribosomal oxygenase 2 enables IBA GO_Central GO_REF:0000033 NCBI chr16:59,292,116...59,312,895
Ensembl chr16:59,292,138...59,312,824 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables IMP (PMID:22192413) MGI PMID:22192413 NCBI chr  Y:1,085,187...1,245,787
Ensembl chr  Y:1,096,861...1,245,759 		JBrowse link
histone H3K36me/H3K36me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm2a lysine (K)-specific demethylase 2A enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr19:4,366,172...4,448,749
Ensembl chr19:4,364,447...4,448,313 		JBrowse link
G Kdm2b lysine (K)-specific demethylase 2B enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886 		JBrowse link
G Phf8 PHD finger protein 8 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr12:83,997,382...83,999,727
Ensembl chr12:83,997,382...83,999,725 		JBrowse link
histone H3K36me2/H3K36me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm4a lysine (K)-specific demethylase 4A enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 4:117,994,154...118,037,216
Ensembl chr 4:117,994,154...118,037,240 		JBrowse link
histone H3K4 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine (K)-specific demethylase 1A enables IMP
ISO
ISS		 (PMID:24217620) MGI
GO_Central
UniProt		 PMID:24217620 GO_REF:0000024 GO_REF:0000119 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm1b lysine (K)-specific demethylase 1B enables IDA (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chr13:47,196,849...47,238,085
Ensembl chr13:47,196,975...47,238,755 		JBrowse link
G Kdm5a lysine demethylase 5A enables IMP (PMID:18483221) MGI PMID:18483221 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535 		JBrowse link
G Kdm5b lysine demethylase 5B enables IDA
ISO		 (PMID:17320160) MGI
GO_Central		 PMID:17320160 GO_REF:0000119 NCBI chr 1:134,487,916...134,560,621
Ensembl chr 1:134,487,909...134,563,023 		JBrowse link
G Kdm5c lysine demethylase 5C enables IDA
ISO		 (PMID:23246292) MGI
GO_Central		 PMID:23246292 GO_REF:0000008 GO_REF:0000119 NCBI chr  X:151,015,698...151,062,098
Ensembl chr  X:151,016,016...151,057,531 		JBrowse link
G Kdm5d lysine demethylase 5D enables ISO MGI GO_REF:0000008 NCBI chr  Y:897,566...946,316
Ensembl chr  Y:897,788...956,786 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IBA GO_Central GO_REF:0000033 NCBI chr12:83,997,382...83,999,727
Ensembl chr12:83,997,382...83,999,725 		JBrowse link
G Riox2 ribosomal oxygenase 2 enables IBA GO_Central GO_REF:0000033 NCBI chr16:59,292,116...59,312,895
Ensembl chr16:59,292,138...59,312,824 		JBrowse link
histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine (K)-specific demethylase 1B NOT|enables IDA (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chr13:47,196,849...47,238,085
Ensembl chr13:47,196,975...47,238,755 		JBrowse link
G Kdm5a lysine demethylase 5A enables IEA
IBA
ISO		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000119 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535 		JBrowse link
G Kdm5b lysine demethylase 5B enables ISO
IBA
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:134,487,916...134,560,621
Ensembl chr 1:134,487,909...134,563,023 		JBrowse link
G Kdm5c lysine demethylase 5C enables IEA
IBA		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  X:151,015,698...151,062,098
Ensembl chr  X:151,016,016...151,057,531 		JBrowse link
G Kdm5d lysine demethylase 5D enables IEA
IBA		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  Y:897,566...946,316
Ensembl chr  Y:897,788...956,786 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IDA (PMID:19927124) UniProt PMID:19927124 NCBI chr12:83,997,382...83,999,727
Ensembl chr12:83,997,382...83,999,725 		JBrowse link
histone H3K9 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr lysine demethylase and nuclear receptor corepressor enables IBA GO_Central GO_REF:0000033 NCBI chr14:70,789,644...70,810,988
Ensembl chr14:70,789,652...70,810,988 		JBrowse link
G Jmjd1c jumonji domain containing 1C enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:66,932,189...67,092,105
Ensembl chr10:66,931,904...67,092,105 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A enables ISS
ISO
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm3a lysine (K)-specific demethylase 3A enables IMP
IBA
ISO
IDA		 (PMID:17943087)
(PMID:17938240), (PMID:17991879)
(PMID:17991879)		 MGI
GO_Central		 PMID:17938240 PMID:17943087 PMID:17991879 GO_REF:0000033 GO_REF:0000119 NCBI chr 6:71,565,954...71,609,963
Ensembl chr 6:71,565,956...71,609,974 		JBrowse link
G Kdm3b KDM3B lysine (K)-specific demethylase 3B enables IBA GO_Central GO_REF:0000033 NCBI chr18:34,910,061...34,972,423
Ensembl chr18:34,910,100...34,971,713 		JBrowse link
G Kdm4a lysine (K)-specific demethylase 4A enables IDA
IBA		 (PMID:16738407) MGI
GO_Central		 PMID:16738407 GO_REF:0000033 NCBI chr 4:117,994,154...118,037,216
Ensembl chr 4:117,994,154...118,037,240 		JBrowse link
G Kdm4b lysine (K)-specific demethylase 4B enables IMP
IBA
ISO
IDA		 (PMID:16738407) MGI
GO_Central		 PMID:16738407 GO_REF:0000033 GO_REF:0000119 NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870 		JBrowse link
G Kdm4c lysine (K)-specific demethylase 4C enables IMP
IBA
ISO
ISS
IDA		 (PMID:17938240)
(PMID:16738407)		 MGI
GO_Central
UniProt		 PMID:16738407 PMID:17938240 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:74,160,734...74,324,101
Ensembl chr 4:74,160,734...74,324,097 		JBrowse link
G Kdm4d lysine (K)-specific demethylase 4D enables IMP
IBA
ISO
IDA		 (PMID:21293030)
(PMID:16738407)
(PMID:24550317)		 MGI
GO_Central		 PMID:16738407 PMID:21293030 PMID:24550317 GO_REF:0000033 GO_REF:0000119 NCBI chr 9:14,373,844...14,411,818
Ensembl chr 9:14,373,844...14,411,778 		JBrowse link
G Kdm7a lysine (K)-specific demethylase 7A enables IMP
ISO		 (PMID:20194436) UniProt
GO_Central		 PMID:20194436 GO_REF:0000119 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723 		JBrowse link
G Phf2 PHD finger protein 2 enables ISS
TAS
ISO		 (PMID:20129925) UniProt
GO_Central		 PMID:20129925 GO_REF:0000024 GO_REF:0000119 NCBI chr13:48,955,226...49,024,361
Ensembl chr13:48,955,226...49,024,595 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
histone H3K9me/H3K9me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr lysine demethylase and nuclear receptor corepressor enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr14:70,789,644...70,810,988
Ensembl chr14:70,789,652...70,810,988 		JBrowse link
G Kdm3a lysine (K)-specific demethylase 3A enables IEA
ISO		 UniProt
RHEA
GO_Central		 GO_REF:0000003 GO_REF:0000116 GO_REF:0000119 NCBI chr 6:71,565,954...71,609,963
Ensembl chr 6:71,565,956...71,609,974 		JBrowse link
G Kdm3b KDM3B lysine (K)-specific demethylase 3B enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr18:34,910,061...34,972,423
Ensembl chr18:34,910,100...34,971,713 		JBrowse link
G Kdm7a lysine (K)-specific demethylase 7A enables IEA RHEA GO_REF:0000116 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723 		JBrowse link
G Phf8 PHD finger protein 8 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
histone H3K9me2/H3K9me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine (K)-specific demethylase 1A enables IMP (PMID:20833138) BHF-UCL PMID:20833138 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm4a lysine (K)-specific demethylase 4A enables IEA
ISO		 RHEA
UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000116 GO_REF:0000119 NCBI chr 4:117,994,154...118,037,216
Ensembl chr 4:117,994,154...118,037,240 		JBrowse link
G Kdm4b lysine (K)-specific demethylase 4B enables IEA
ISO		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000116 GO_REF:0000119 NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870 		JBrowse link
G Kdm4c lysine (K)-specific demethylase 4C enables
contributes_to		 IEA
ISO		 UniProt
RHEA
GO_Central		 GO_REF:0000003 GO_REF:0000116 GO_REF:0000119 NCBI chr 4:74,160,734...74,324,101
Ensembl chr 4:74,160,734...74,324,097 		JBrowse link
G Kdm4d lysine (K)-specific demethylase 4D enables IEA
ISO		 RHEA
GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000116 GO_REF:0000119 NCBI chr 9:14,373,844...14,411,818
Ensembl chr 9:14,373,844...14,411,778 		JBrowse link
histone H3R2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6 enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275 		JBrowse link
histone H4K20 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm7a lysine (K)-specific demethylase 7A enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723 		JBrowse link
G Phf2 PHD finger protein 2 enables IMP (PMID:22921934) UniProt PMID:22921934 NCBI chr13:48,955,226...49,024,361
Ensembl chr13:48,955,226...49,024,595 		JBrowse link
G Phf8 PHD finger protein 8 enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:150,303,621...150,416,855
Ensembl chr  X:150,303,668...150,416,855 		JBrowse link
G Rsbn1 rosbin, round spermatid basic protein 1 enables IDA (PMID:28867287) FlyBase PMID:28867287 NCBI chr 3:103,821,412...103,873,952
Ensembl chr 3:103,821,436...103,873,952 		JBrowse link
histone H4R3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6 enables IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275 		JBrowse link
mRNA N1-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152 		JBrowse link
mRNA N6-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh5 alkB homolog 5, RNA demethylase enables ISO
IMP
ISS		 (PMID:29279410), (PMID:35939687), (PMID:36859428) GO_Central
UniProt		 PMID:29279410 PMID:35939687 PMID:36859428 GO_REF:0000024 GO_REF:0000119 NCBI chr11:60,428,509...60,449,338
Ensembl chr11:60,427,207...60,449,338 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase enables IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
oxidative RNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr12:87,474,847...87,490,609
Ensembl chr12:87,472,610...87,490,787 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables IDA
ISO		 (PMID:16174769) UniProt
GO_Central		 PMID:16174769 GO_REF:0000119 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152 		JBrowse link
G Alkbh5 alkB homolog 5, RNA demethylase enables IBA GO_Central GO_REF:0000033 NCBI chr11:60,428,509...60,449,338
Ensembl chr11:60,427,207...60,449,338 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase enables IDA
ISO		 (PMID:18775698) BHF-UCL
GO_Central		 PMID:18775698 GO_REF:0000119 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
G Jmjd6 jumonji domain containing 6 enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275 		JBrowse link
protein demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6 enables ISO GO_Central GO_REF:0000119 NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IDA
ISO		 (PMID:35210392) UniProt
GO_Central		 PMID:35210392 GO_REF:0000119 NCBI chr12:83,997,382...83,999,727
Ensembl chr12:83,997,382...83,999,725 		JBrowse link
sterol 14-demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 enables ISO
ISS
TAS		 (PMID:10864439) RGD
GO_Central
UniProt
MGI		 PMID:7581240 PMID:7665087 PMID:10864439 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 RGD:1298863 RGD:2316902 NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746 		JBrowse link
tRNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr12:87,474,847...87,490,609
Ensembl chr12:87,472,610...87,490,787 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28792
    catalytic activity 5722
      demethylase activity 45
        DNA demethylase activity + 5
        methylselenol demethylase activity 0
        oxidative RNA demethylase activity + 5
        protein demethylase activity + 30
        sterol 14-demethylase activity 1
        vanillate monooxygenase activity 0
paths to the root