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ONTOLOGY REPORT - ANNOTATIONS

Term:demethylase activity
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Accession:GO:0032451 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a substrate.


show annotations for term's descendants           Sort by:
demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH4 alkB homolog 4, lysine demethylase enables IBA GO_Central GO_REF:0000033 NCBI chr 7:102,456,238...102,464,863
Ensembl chr 7:102,456,238...102,464,863 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 enables ISO
IEA		 N-demethylation of benzphetamine, aminopyrine
N-demethylation of amitriptyline, erythromycin, diazapam, imipramine, lidocaine, morphine		 RGD
Ensembl		 PMID:10915793 PMID:11370669 GO_REF:0000107 RGD:2306679 RGD:2306680 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 enables IDA (PMID:2813353) UniProt PMID:2813353 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 ISO RGD PMID:12971802 RGD:5129544 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G KDM1A lysine demethylase 1A enables IMP (PMID:17805299) BHF-UCL PMID:17805299 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G MMACHC metabolism of cobalamin associated C enables IDA
IBA		 (PMID:19801555) UniProt
GO_Central		 PMID:19801555 GO_REF:0000033 NCBI chr 1:45,500,300...45,513,382
Ensembl chr 1:45,500,300...45,513,382 		JBrowse link
broad specificity oxidative DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH1 alkB homolog 1, histone H2A dioxygenase enables IEA
IBA
IDA		 (PMID:18603530), (PMID:30017583), (PMID:30392959) Ensembl
GO_Central
UniProt
RHEA		 PMID:18603530 PMID:30017583 PMID:30392959 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr14:77,672,404...77,708,023
Ensembl chr14:77,672,404...77,708,023 		JBrowse link
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase enables IEA
IBA
IDA		 (PMID:12486230), (PMID:16174769), (PMID:18432238), (PMID:20714506) UniProt
GO_Central
Ensembl
RHEA		 PMID:12486230 PMID:16174769 PMID:18432238 PMID:20714506 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr12:109,088,189...109,093,472
Ensembl chr12:109,088,188...109,093,631 		JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase enables IEA
IDA
IMP		 (PMID:12486230), (PMID:16174769), (PMID:16858410), (PMID:20714506)
(PMID:22055184)		 RHEA
UniProt		 PMID:12486230 PMID:16174769 PMID:16858410 PMID:20714506 PMID:22055184 GO_REF:0000116 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274 		JBrowse link
G ALKBH4 alkB homolog 4, lysine demethylase enables IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:102,456,238...102,464,863
Ensembl chr 7:102,456,238...102,464,863 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase enables IEA
IBA
IDA		 (PMID:18775698), (PMID:20376003) InterPro
GO_Central
UniProt
Ensembl		 PMID:18775698 PMID:20376003 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
cytosine C-5 DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase enables IEA
IBA
IDA		 (PMID:18432238) Ensembl
GO_Central
UniProt		 PMID:18432238 GO_REF:0000033 GO_REF:0000107 NCBI chr12:109,088,189...109,093,472
Ensembl chr12:109,088,188...109,093,631 		JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase enables ISO (PMID:16174769) MGI PMID:16174769 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274 		JBrowse link
DNA N6-methyladenine demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH1 alkB homolog 1, histone H2A dioxygenase enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr14:77,672,404...77,708,023
Ensembl chr14:77,672,404...77,708,023 		JBrowse link
G ALKBH4 alkB homolog 4, lysine demethylase enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 7:102,456,238...102,464,863
Ensembl chr 7:102,456,238...102,464,863 		JBrowse link
FAD-dependent H3K4me/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1A lysine demethylase 1A enables IEA
IBA
IDA		 (PMID:20228790), (PMID:27292636) RHEA
GO_Central
UniProt		 PMID:20228790 PMID:27292636 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G KDM1B lysine demethylase 1B enables IEA
IBA
IDA		 (PMID:23260659), (PMID:23266887), (PMID:23357850), (PMID:30970244) Ensembl
GO_Central
UniProt
RHEA		 PMID:23260659 PMID:23266887 PMID:23357850 PMID:30970244 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 NCBI chr 6:18,155,422...18,223,854
Ensembl chr 6:18,155,329...18,223,854 		JBrowse link
FAD-dependent histone H3K9me/H3K9me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HR HR lysine demethylase and nuclear receptor corepressor enables IEA UniProt GO_REF:0000003 NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384 		JBrowse link
G KDM3A lysine demethylase 3A enables IEA UniProt GO_REF:0000003 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KDM3B lysine demethylase 3B enables IEA UniProt GO_REF:0000003 NCBI chr 5:138,352,685...138,437,027
Ensembl chr 5:138,352,685...138,437,028 		JBrowse link
G PHF8 PHD finger protein 8 enables IEA UniProt GO_REF:0000003 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
histone demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXL19 F-box and leucine rich repeat protein 19 enables IBA GO_Central GO_REF:0000033 NCBI chr16:30,922,851...30,948,783
Ensembl chr16:30,923,055...30,948,783 		JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 NOT|enables ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:15,246,069...15,522,042
Ensembl chr 6:15,246,069...15,522,042 		JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables TAS
IDA		 (PMID:24498420) Reactome
UniProt		 PMID:24498420 Reactome:R-HSA-4754176 Reactome:R-HSA-5661122 Reactome:R-HSA-5661124 Reactome:R-HSA-5661125 NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799 		JBrowse link
G KDM1A lysine demethylase 1A enables TAS
IDA
EXP		 (PMID:19497860)
(PMID:16079795), (PMID:18066052)		 Reactome
BHF-UCL		 PMID:16079795 PMID:18066052 PMID:19497860 Reactome:R-HSA-3214912 Reactome:R-HSA-5661123 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G KDM1B lysine demethylase 1B enables TAS Reactome Reactome:R-HSA-3214912 Reactome:R-HSA-5661123 NCBI chr 6:18,155,422...18,223,854
Ensembl chr 6:18,155,329...18,223,854 		JBrowse link
G KDM2A lysine demethylase 2A enables TAS
IBA		 Reactome
GO_Central		 GO_REF:0000033 Reactome:R-HSA-4722133 Reactome:R-HSA-5661114 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082 		JBrowse link
G KDM2B lysine demethylase 2B enables TAS
IBA		 (PMID:21220025) Reactome
GO_Central		 PMID:21220025 GO_REF:0000033 Reactome:R-HSA-4722133 Reactome:R-HSA-5661114 NCBI chr12:121,408,461...121,582,279
Ensembl chr12:121,429,096...121,582,279 		JBrowse link
G KDM4A lysine demethylase 4A enables TAS
IEA		 Reactome
Ensembl		 GO_REF:0000107 Reactome:R-HSA-4722133 Reactome:R-HSA-4724279 Reactome:R-HSA-5661114 Reactome:R-HSA-5661120 NCBI chr 1:43,650,149...43,705,518
Ensembl chr 1:43,650,149...43,705,518 		JBrowse link
G KDM4B lysine demethylase 4B enables TAS
IEA		 Reactome
Ensembl		 GO_REF:0000107 Reactome:R-HSA-4724279 Reactome:R-HSA-5661120 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,611 		JBrowse link
G KDM4C lysine demethylase 4C enables EXP
TAS
IEA		 (PMID:18066052) Reactome
Ensembl		 PMID:18066052 GO_REF:0000107 Reactome:R-HSA-4724279 Reactome:R-HSA-5661120 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648 		JBrowse link
G KDM4D lysine demethylase 4D enables TAS
IEA		 Reactome
Ensembl		 GO_REF:0000107 Reactome:R-HSA-4724279 Reactome:R-HSA-5661120 NCBI chr11:94,973,709...94,999,519
Ensembl chr11:94,973,709...94,999,519 		JBrowse link
G KDM5A lysine demethylase 5A enables TAS Reactome Reactome:R-HSA-4754181 Reactome:R-HSA-5661116 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KDM5B lysine demethylase 5B enables TAS Reactome Reactome:R-HSA-4754181 Reactome:R-HSA-5661116 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487 		JBrowse link
G KDM5C lysine demethylase 5C enables TAS Reactome Reactome:R-HSA-4754181 Reactome:R-HSA-5661116 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,176,277...53,225,422 		JBrowse link
G KDM5D lysine demethylase 5D enables TAS Reactome Reactome:R-HSA-4754181 Reactome:R-HSA-5661116 NCBI chr  Y:19,703,865...19,744,726
Ensembl chr  Y:19,703,865...19,744,939 		JBrowse link
G KDM6A lysine demethylase 6A enables TAS
IEA		 Reactome
UniProt		 GO_REF:0000117 Reactome:R-HSA-4754187 Reactome:R-HSA-5661121 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779 		JBrowse link
G KDM6B lysine demethylase 6B enables TAS
IEA		 Reactome
UniProt		 GO_REF:0000117 Reactome:R-HSA-4754187 Reactome:R-HSA-5661121 NCBI chr17:7,834,217...7,854,796
Ensembl chr17:7,834,217...7,854,796 		JBrowse link
G KDM7A lysine demethylase 7A enables TAS
IBA		 Reactome
GO_Central		 GO_REF:0000033 Reactome:R-HSA-4754187 Reactome:R-HSA-5661121 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G PHF2 PHD finger protein 2 NOT|enables IDA (PMID:21167174) UniProt PMID:21167174 NCBI chr 9:93,576,584...93,679,587
Ensembl chr 9:93,576,584...93,679,587 		JBrowse link
G PHF8 PHD finger protein 8 enables TAS
IBA
IDA		 (PMID:19843542) Reactome
GO_Central
UniProt		 PMID:19843542 GO_REF:0000033 Reactome:R-HSA-5423117 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
G RIOX2 ribosomal oxygenase 2 enables TAS Reactome Reactome:R-HSA-4724279 Reactome:R-HSA-5661120 NCBI chr 3:97,941,818...97,972,431
Ensembl chr 3:97,941,818...97,972,457 		JBrowse link
G UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables TAS
IEA		 Reactome
UniProt		 GO_REF:0000117 Reactome:R-HSA-4754187 Reactome:R-HSA-5661121 NCBI chr  Y:13,233,895...13,480,670
Ensembl chr  Y:13,234,577...13,480,673 		JBrowse link
histone H3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM2A lysine demethylase 2A enables IEA UniProt GO_REF:0000117 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082 		JBrowse link
G KDM2B lysine demethylase 2B enables IEA UniProt GO_REF:0000117 NCBI chr12:121,408,461...121,582,279
Ensembl chr12:121,429,096...121,582,279 		JBrowse link
G KDM4B lysine demethylase 4B enables IEA UniProt GO_REF:0000117 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,611 		JBrowse link
G KDM4C lysine demethylase 4C enables IEA UniProt GO_REF:0000117 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648 		JBrowse link
G KDM5A lysine demethylase 5A enables IEA UniProt GO_REF:0000117 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KDM5B lysine demethylase 5B enables IEA UniProt GO_REF:0000117 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487 		JBrowse link
G KDM5C lysine demethylase 5C enables IEA UniProt GO_REF:0000117 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,176,277...53,225,422 		JBrowse link
G KDM5D lysine demethylase 5D enables IEA UniProt GO_REF:0000117 NCBI chr  Y:19,703,865...19,744,726
Ensembl chr  Y:19,703,865...19,744,939 		JBrowse link
G KDM7A lysine demethylase 7A enables IEA UniProt GO_REF:0000117 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G PHF8 PHD finger protein 8 enables IEA UniProt GO_REF:0000117 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
histone H3K27me2/H3K27me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM6A lysine demethylase 6A enables IEA
IBA		 RHEA
GO_Central
Ensembl
UniProt		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779 		JBrowse link
G KDM6B lysine demethylase 6B enables IEA
IBA
IMP		 (PMID:28262558) Ensembl
GO_Central
UniProt
RHEA		 PMID:28262558 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr17:7,834,217...7,854,796
Ensembl chr17:7,834,217...7,854,796 		JBrowse link
G KDM7A lysine demethylase 7A enables IEA
IDA		 (PMID:20023638), (PMID:20194436), (PMID:20622853) Ensembl
UniProt		 PMID:20023638 PMID:20194436 PMID:20622853 GO_REF:0000107 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G PHF8 PHD finger protein 8 enables IDA (PMID:20622853), (PMID:20622854) UniProt PMID:20622853 PMID:20622854 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
G UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables IEA
IBA		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  Y:13,233,895...13,480,670
Ensembl chr  Y:13,234,577...13,480,673 		JBrowse link
histone H3K36 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM2A lysine demethylase 2A enables IMP (PMID:20417597), (PMID:21187428), (PMID:28262558) UniProt PMID:20417597 PMID:21187428 PMID:28262558 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082 		JBrowse link
G KDM2B lysine demethylase 2B enables IDA
IEA		 (PMID:26237645) UniProt
Ensembl		 PMID:26237645 GO_REF:0000107 NCBI chr12:121,408,461...121,582,279
Ensembl chr12:121,429,096...121,582,279 		JBrowse link
G KDM4A lysine demethylase 4A enables IDA
IBA		 (PMID:16024779), (PMID:21914792) UniProt
GO_Central		 PMID:16024779 PMID:21914792 GO_REF:0000033 NCBI chr 1:43,650,149...43,705,518
Ensembl chr 1:43,650,149...43,705,518 		JBrowse link
G KDM4B lysine demethylase 4B enables IDA
IEA		 (PMID:21914792) UniProt
Ensembl		 PMID:21914792 GO_REF:0000107 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,611 		JBrowse link
G KDM4C lysine demethylase 4C enables IDA
IBA		 (PMID:21914792) UniProt
GO_Central		 PMID:21914792 GO_REF:0000033 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648 		JBrowse link
G KDM7A lysine demethylase 7A enables IDA (PMID:20622853) UniProt PMID:20622853 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G KDM8 lysine demethylase 8 enables IDA
IBA		 (PMID:20457893) UniProt
GO_Central		 PMID:20457893 GO_REF:0000033 NCBI chr16:27,203,526...27,221,768
Ensembl chr16:27,203,508...27,221,768 		JBrowse link
G PHF8 PHD finger protein 8 enables IDA (PMID:20208542), (PMID:20622853) UniProt PMID:20208542 PMID:20622853 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
G RIOX1 ribosomal oxygenase 1 enables IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:73,490,933...73,493,394
Ensembl chr14:73,490,933...73,493,394 		JBrowse link
G RIOX2 ribosomal oxygenase 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:97,941,818...97,972,431
Ensembl chr 3:97,941,818...97,972,457 		JBrowse link
G UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables ISO (PMID:22192413) MGI PMID:22192413 NCBI chr  Y:13,233,895...13,480,670
Ensembl chr  Y:13,234,577...13,480,673 		JBrowse link
histone H3K36me/H3K36me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM2A lysine demethylase 2A enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082 		JBrowse link
G KDM2B lysine demethylase 2B enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr12:121,408,461...121,582,279
Ensembl chr12:121,429,096...121,582,279 		JBrowse link
G PHF8 PHD finger protein 8 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
G RIOX1 ribosomal oxygenase 1 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr14:73,490,933...73,493,394
Ensembl chr14:73,490,933...73,493,394 		JBrowse link
histone H3K36me2/H3K36me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM4A lysine demethylase 4A enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:43,650,149...43,705,518
Ensembl chr 1:43,650,149...43,705,518 		JBrowse link
histone H3K4 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1A lysine demethylase 1A enables IDA (PMID:15620353), (PMID:24217620), (PMID:27292636) UniProt PMID:15620353 PMID:24217620 PMID:27292636 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G KDM1B lysine demethylase 1B enables IEA Ensembl GO_REF:0000107 NCBI chr 6:18,155,422...18,223,854
Ensembl chr 6:18,155,329...18,223,854 		JBrowse link
G KDM5A lysine demethylase 5A enables IEA Ensembl GO_REF:0000107 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KDM5B lysine demethylase 5B enables IEA
IMP
IDA		 (PMID:24952722), (PMID:27214403), (PMID:28262558)
(PMID:18048344)		 Ensembl
UniProt
CACAO		 PMID:18048344 PMID:24952722 PMID:27214403 PMID:28262558 GO_REF:0000107 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487 		JBrowse link
G KDM5C lysine demethylase 5C enables IMP
IEA
IDA		 (PMID:28262558)
(PMID:17320160), (PMID:18078810)		 UniProt
Ensembl
MGI		 PMID:17320160 PMID:18078810 PMID:28262558 GO_REF:0000107 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,176,277...53,225,422 		JBrowse link
G KDM5D lysine demethylase 5D enables IDA (PMID:17320160) MGI PMID:17320160 NCBI chr  Y:19,703,865...19,744,726
Ensembl chr  Y:19,703,865...19,744,939 		JBrowse link
G RIOX1 ribosomal oxygenase 1 enables IBA GO_Central GO_REF:0000033 NCBI chr14:73,490,933...73,493,394
Ensembl chr14:73,490,933...73,493,394 		JBrowse link
G RIOX2 ribosomal oxygenase 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:97,941,818...97,972,431
Ensembl chr 3:97,941,818...97,972,457 		JBrowse link
histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1B lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chr 6:18,155,422...18,223,854
Ensembl chr 6:18,155,329...18,223,854 		JBrowse link
G KDM5A lysine demethylase 5A enables IDA
IBA
IEA		 (PMID:18270511) CAFA
GO_Central
UniProt
RHEA		 PMID:18270511 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KDM5B lysine demethylase 5B enables IEA
IBA
IMP
IDA		 (PMID:20403335)
(PMID:20228790)		 RHEA
GO_Central
CAFA
UniProt		 PMID:20228790 PMID:20403335 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487 		JBrowse link
G KDM5C lysine demethylase 5C enables IEA
IBA		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,176,277...53,225,422 		JBrowse link
G KDM5D lysine demethylase 5D enables IEA
IBA		 UniProt
GO_Central
RHEA		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  Y:19,703,865...19,744,726
Ensembl chr  Y:19,703,865...19,744,939 		JBrowse link
G RIOX1 ribosomal oxygenase 1 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:73,490,933...73,493,394
Ensembl chr14:73,490,933...73,493,394 		JBrowse link
histone H3K9 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HR HR lysine demethylase and nuclear receptor corepressor enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384 		JBrowse link
G JMJD1C jumonji domain containing 1C enables TAS
IBA
IEA		 Reactome
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-997263 NCBI chr10:63,167,225...63,521,890
Ensembl chr10:63,167,221...63,521,850 		JBrowse link
G KDM1A lysine demethylase 1A enables IDA
TAS		 (PMID:16079795), (PMID:20228790) UniProt
Reactome		 PMID:16079795 PMID:20228790 Reactome:R-HSA-9011985 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G KDM3A lysine demethylase 3A enables IMP
IBA
IEA		 (PMID:28262558) UniProt
GO_Central
Ensembl
InterPro		 PMID:28262558 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KDM3B lysine demethylase 3B enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:138,352,685...138,437,027
Ensembl chr 5:138,352,685...138,437,028 		JBrowse link
G KDM4A lysine demethylase 4A enables IEA
IBA		 Ensembl
GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:43,650,149...43,705,518
Ensembl chr 1:43,650,149...43,705,518 		JBrowse link
G KDM4B lysine demethylase 4B enables IEA
IBA
TAS
IMP		 (PMID:28262558) Ensembl
GO_Central
UniProt
Reactome		 PMID:28262558 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 Reactome:R-HSA-9011949 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,611 		JBrowse link
G KDM4C lysine demethylase 4C enables IDA
IBA
IMP
IEA		 (PMID:18066052)
(PMID:28262558)		 UniProt
GO_Central
Ensembl		 PMID:18066052 PMID:28262558 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648 		JBrowse link
G KDM4D lysine demethylase 4D enables IEA
IBA
IDA		 (PMID:25124442) Ensembl
GO_Central
WB		 PMID:25124442 GO_REF:0000033 GO_REF:0000107 NCBI chr11:94,973,709...94,999,519
Ensembl chr11:94,973,709...94,999,519 		JBrowse link
G KDM4E lysine demethylase 4E enables IBA GO_Central GO_REF:0000033 NCBI chr11:95,025,258...95,027,596
Ensembl chr11:95,025,258...95,027,596 		JBrowse link
G KDM4F lysine demethylase 4F enables IBA GO_Central GO_REF:0000033 NCBI chr11:95,049,422...95,051,338
Ensembl chr11:95,048,142...95,051,338 		JBrowse link
G KDM7A lysine demethylase 7A enables IEA
IDA		 (PMID:20023638), (PMID:20194436), (PMID:20622853) Ensembl
UniProt		 PMID:20023638 PMID:20194436 PMID:20622853 GO_REF:0000107 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G PHF2 PHD finger protein 2 enables IDA (PMID:21532585) UniProt PMID:21532585 NCBI chr 9:93,576,584...93,679,587
Ensembl chr 9:93,576,584...93,679,587 		JBrowse link
G PHF8 PHD finger protein 8 enables IDA (PMID:20023638), (PMID:20208542), (PMID:20346720), (PMID:20622853), (PMID:20622854) UniProt PMID:20023638 PMID:20208542 PMID:20346720 PMID:20622853 PMID:20622854 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
histone H3K9me/H3K9me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HR HR lysine demethylase and nuclear receptor corepressor enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384 		JBrowse link
G KDM3A lysine demethylase 3A enables IEA
IDA		 (PMID:16603237) UniProt
FlyBase
RHEA		 PMID:16603237 GO_REF:0000003 GO_REF:0000116 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KDM3B lysine demethylase 3B enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 5:138,352,685...138,437,027
Ensembl chr 5:138,352,685...138,437,028 		JBrowse link
G KDM7A lysine demethylase 7A enables IEA RHEA GO_REF:0000116 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G PHF8 PHD finger protein 8 enables IEA RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
histone H3K9me2/H3K9me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1A lysine demethylase 1A enables ISO (PMID:20833138) BHF-UCL PMID:20833138 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G KDM4A lysine demethylase 4A enables IEA
IMP		 (PMID:21914792) RHEA
UniProt		 PMID:21914792 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:43,650,149...43,705,518
Ensembl chr 1:43,650,149...43,705,518 		JBrowse link
G KDM4B lysine demethylase 4B enables IEA
IDA		 (PMID:21914792) RHEA
UniProt		 PMID:21914792 GO_REF:0000003 GO_REF:0000116 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,611 		JBrowse link
G KDM4C lysine demethylase 4C enables IEA
IMP
IDA		 (PMID:17277772)
(PMID:21914792)		 UniProt
BHF-UCL
RHEA		 PMID:17277772 PMID:21914792 GO_REF:0000003 GO_REF:0000116 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648 		JBrowse link
G KDM4D lysine demethylase 4D enables IEA
IDA		 (PMID:21914792) RHEA
UniProt		 PMID:21914792 GO_REF:0000003 GO_REF:0000116 NCBI chr11:94,973,709...94,999,519
Ensembl chr11:94,973,709...94,999,519 		JBrowse link
G KDM4E lysine demethylase 4E enables IEA
IDA		 (PMID:21914792) RHEA
UniProt		 PMID:21914792 GO_REF:0000003 GO_REF:0000116 NCBI chr11:95,025,258...95,027,596
Ensembl chr11:95,025,258...95,027,596 		JBrowse link
histone H3R2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables IDA (PMID:17947579) UniProt PMID:17947579 NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799 		JBrowse link
histone H4K20 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM7A lysine demethylase 7A enables IDA (PMID:20622853) UniProt PMID:20622853 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983 		JBrowse link
G PHF2 PHD finger protein 2 enables ISS UniProt GO_REF:0000024 NCBI chr 9:93,576,584...93,679,587
Ensembl chr 9:93,576,584...93,679,587 		JBrowse link
G PHF8 PHD finger protein 8 enables IDA (PMID:20622853) UniProt PMID:20622853 NCBI chr  X:53,936,680...54,048,936
Ensembl chr  X:53,936,676...54,048,958 		JBrowse link
G RSBN1 round spermatid basic protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:113,761,832...113,812,476
Ensembl chr 1:113,761,832...113,812,476 		JBrowse link
histone H4R3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables IDA
IBA		 (PMID:17947579), (PMID:24360279) UniProt
GO_Central		 PMID:17947579 PMID:24360279 GO_REF:0000033 NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799 		JBrowse link
mRNA N1-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase enables IEA
IDA		 (PMID:26863196), (PMID:26863410) UniProt
RHEA		 PMID:26863196 PMID:26863410 GO_REF:0000003 GO_REF:0000116 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274 		JBrowse link
mRNA N6-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH5 alkB homolog 5, RNA demethylase enables IEA
IDA		 (PMID:23177736), (PMID:24616105), (PMID:34048572), (PMID:35333330), (PMID:36944332), (PMID:37257451), (PMID:37369679), (PMID:37474102) RHEA
UniProt
Ensembl		 PMID:23177736 PMID:24616105 PMID:34048572 PMID:35333330 PMID:36944332 More... GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr17:18,183,828...18,209,954
Ensembl chr17:18,183,078...18,209,954 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase enables IDA
IBA
IMP
IEA		 (PMID:25452335), (PMID:26457839), (PMID:30197295)
(PMID:26458103)		 UniProt
GO_Central
RHEA		 PMID:25452335 PMID:26457839 PMID:26458103 PMID:30197295 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
oxidative RNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH1 alkB homolog 1, histone H2A dioxygenase enables IBA
IDA		 (PMID:18603530), (PMID:31188562) GO_Central
UniProt		 PMID:18603530 PMID:31188562 GO_REF:0000033 NCBI chr14:77,672,404...77,708,023
Ensembl chr14:77,672,404...77,708,023 		JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase enables IDA (PMID:16174769) UniProt PMID:16174769 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274 		JBrowse link
G ALKBH5 alkB homolog 5, RNA demethylase enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr17:18,183,828...18,209,954
Ensembl chr17:18,183,078...18,209,954 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase enables IEA
IDA		 (PMID:18775698), (PMID:22002720), (PMID:28002401), (PMID:30197295) InterPro
UniProt
Ensembl		 PMID:18775698 PMID:22002720 PMID:28002401 PMID:30197295 GO_REF:0000002 GO_REF:0000107 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables IMP (PMID:24360279) UniProt PMID:24360279 NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799 		JBrowse link
protein demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH4 alkB homolog 4, lysine demethylase enables TAS (PMID:23673617) UniProt PMID:23673617 NCBI chr 7:102,456,238...102,464,863
Ensembl chr 7:102,456,238...102,464,863 		JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables IDA (PMID:24498420) UniProt PMID:24498420 NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799 		JBrowse link
G RIOX1 ribosomal oxygenase 1 enables IEA
IDA		 (PMID:35210392) Ensembl
UniProt		 PMID:35210392 GO_REF:0000107 NCBI chr14:73,490,933...73,493,394
Ensembl chr14:73,490,933...73,493,394 		JBrowse link
sterol 14-demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 enables ISO
IEA
IDA		 (PMID:20149798) RGD
RHEA
UniProt		 PMID:7581240 PMID:7665087 PMID:20149798 GO_REF:0000003 GO_REF:0000116 RGD:1298863 RGD:2316902 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
tRNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH1 alkB homolog 1, histone H2A dioxygenase enables IDA (PMID:27745969) UniProt PMID:27745969 NCBI chr14:77,672,404...77,708,023
Ensembl chr14:77,672,404...77,708,023 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase enables IDA (PMID:30197295) UniProt PMID:30197295 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19524
    catalytic activity 6003
      demethylase activity 42
        DNA demethylase activity + 5
        methylselenol demethylase activity 0
        oxidative RNA demethylase activity + 5
        protein demethylase activity + 32
        sterol 14-demethylase activity 1
        vanillate monooxygenase activity 0
paths to the root