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Term:activin responsive factor complex
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Accession:GO:0032444 term browser browse the term
Definition:A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.
Comment:Note that this term should not be confused with any of the molecular function and biological process terms that refer to the small GTPase ARF (ADP-ribosylation factor).
Synonyms:exact_synonym: ARF complex

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activin responsive factor complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxh1 forkhead box H1 ISO
(MGI:MGI:1321467|PMID:9858566), (MGI:MGI:1328655|PMID:10349617)
RGD PMID:9389648, PMID:9858566, PMID:10349617, PMID:21873635 MGI:MGI:1321467, MGI:MGI:1328655, RGD:13792537 NCBI chr 7:117,730,307...117,733,076
Ensembl chr 7:117,730,307...117,732,387
JBrowse link
G Smad2 SMAD family member 2 ISO (PMID:9389648) RGD PMID:9389648 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad4 SMAD family member 4 ISO
PMID:9389648 GO_REF:0000107 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link

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  cellular_component 20609
    protein-containing complex 6093
      transcription regulator complex 434
        RNA polymerase II transcription regulator complex 162
          activin responsive factor complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.